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Introduction About DIOMINIC TABLET
DIOMINIC TABLET contains Dexchlorpheniramine which belongs to the group of medicines called Antihistamines. It is used to manage perennial, seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild uncomplicated allergic skin manifestations of urticaria and angioedema (swelling underneath skin).
Allergic rhinitis is a diagnosis associated with a group of symptoms affecting the nose caused by irritation and inflammation of the nasal membrane. These symptoms occur when you breathe in something you are allergic to, such as dust, pollen or animal dander. Symptoms are sneezing, itchiness and a blocked or runny nose.
DIOMINIC TABLET may provide relief from itching caused by skin conditions such as allergic eczema, pruritus ani, pruritus vulvae, atopic dermatitis, contact dermatitis, insect bites, dermographism and medication reactions (serum sickness).
Before taking this medicine DIOMINIC TABLET inform your doctor if you have liver, kidney or heart disease, glaucoma (increased pressure in the eye), enlargement of prostrate, hyperthyroidism or seizures.
DIOMINIC TABLET should be used in pregnant women only if clearly needed and should not be taken during last 3 months of pregnancy. It should be used with caution in breastfeeding women as it passes through breast milk. Consult with your doctor before taking DIOMINIC TABLET.
DIOMINIC TABLET is not recommended for use in children below 2 years of age. It should be used with caution in elderly patients above 60 years of age. Ask for your doctor’s advice before taking DIOMINIC TABLET.
The common side effects of taking DIOMINIC TABLET are drowsiness, headache, blurred vision and dry mouth. Consult with your doctor if any of these worsen or doesn’t improve.
Uses Of DIOMINIC TABLET
Manage:
- perennial, seasonal allergic rhinitis
- vasomotor rhinitis
- allergic conjunctivitis
- mild uncomplicated allergic skin manifestations of urticaria and angioedema
How DIOMINIC TABLET Works
DIOMINIC TABLET acts by inhibiting the effects of histamine, a naturally occurring chemical in the body which is responsible for causing the allergic symptoms.
How to use DIOMINIC TABLET
Always take this DIOMINIC TABLET as prescribed by the doctor. Swallow the medicine as a whole, do not crush or chew. Your doctor will prescribe the right dose and frequency depending on your age, body weight and severity of infection.
Side Effects Of DIOMINIC TABLET
Common
- disturbance in concentrating
- un-coordination
- dizziness
- headache
- blurred vision
- nausea, vomiting
- dry mouth
- fatigue
- drowsiness
- sedation (sleepiness)
Rare
Stop taking DIOMINIC TABLET and contact your doctor immediately if you notice any of the following side effects:
- chest pain
- sudden signs of allergy such as rash, hives, swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing
- convulsions, fits or seizures
- coma
- fast, pounding or irregular heartbeats
- tiredness, headache, dizziness, spinning sensation, with yellowing of the skin and/or eyes
- unable or difficulty passing urine, passing urine more often than usual
- hallucinations
- tingling or numbness in the hands or feet, also known as 'pins and needles'
How To Manage Side Effects
Nausea:
Take this medicine with or after meals. Stick to simple meals while taking this medicine. Avoid eating rich or spicy food. Do not take any medication on your own. Ask for your doctor’s advice if nausea doesn’t improve.
Headache:
Try to take rest and don’t involve yourself in exertive activities. Rest in a quiet and dark room. Apply a pain-relieving balm on your forehead. Ask for your doctor’s advice if headache doesn’t improve
Vomiting:
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, oily or sweet foods. Avoid carbonated drinks. Ask for your doctor’s advice if vomiting doesn’t improve.
Dizziness:
Lie or sit down immediately when you feel dizzy. If you're feeling severe episode of spinning(vertigo), lie in a dark and quite place with eyes closed. Try to avoid vehicle driving. Discuss with your doctor if the symptom worsens.
Dry mouth:
Dry mouth can be managed by chewing sugar-free gum or sucking on sugar-free hard candies to stimulate the flow of saliva. Sip water at regular intervals of time. Do not use mouthwashes that contain alcohol because they can be drying. Consult your physician for advice.
Warning & Precautions
Pregnancy
DIOMINIC TABLET should be used in pregnant women only if clearly needed and should not be taken during last 3 months of pregnancy. Consult your doctor for advice.
Breastfeeding
DIOMINIC TABLET it should be used with caution during breastfeeding as it passes through the breast milk. Consult your doctor for advice.
Driving and Using Machines
Do not drive or handle any machines if you experience drowsiness after taking DIOMINIC TABLET.
Alcohol
Do not consume alcohol while taking DIOMINIC TABLET as it may cause drowsiness.
Kidney
DIOMINIC TABLET should be used with caution in patients with kidney disease. Consult your doctor for advice.
Liver
DIOMINIC TABLET should be used with caution in patients with liver disease. Consult your doctor for advice.
Allergy
Tell your doctor if you are allergic (hypersensitive) to Dexchlorpheniramine or any other ingredients of this medicine.
Heart Disease
DIOMINIC TABLET should be used with caution in patients with heart problems. Consult your doctor for advice.
Others
Before taking DIOMINIC TABLET, tell your doctor if you have:
- narrow-angle glaucoma
- stenosing peptic ulcer
- enlarged prostate gland
- bladder neck obstruction
- pyloroduodenal obstruction
- hypertension (high blood pressure)
- hyperthyroidism
- seizure
Use in Pediatrics:
DIOMINIC TABLET is not recommended for use in children below 2 years of age. Consult with your child’s doctor before giving it to your child.
Use in Geriatrics:
DIOMINIC TABLET should be used with caution in elderly patients (above 60 years of age). The elderly may experience paradoxical excitation, dizziness, sedation, hypotension, central nervous system side effects and confusion. Consult your doctor for advice.
Interactions
A. Drug - Drug interactions:
Before taking DIOMINIC TABLET, inform your physician if you are taking any of the following medicines:
- zolpidem, triazolam, midazolam, phenobarbital (used to induce sleep)
- opioid analgesics such as tramadol, fentanyl (used to manage severe pain)
- amitriptyline, imipramine, isocarboxazid (used to manage depression)
- oral anticoagulants such as heparin (used to manage blood clot)
Overdosage:
If you or anyone else accidentally take too much of DIOMINIC TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage include central nervous system depression, apnoea, arrhythmias, cardiovascular problem, cyanosis, diminished mental alertness, sedation, convulsions, hallucinations, insomnia, tremors, ataxia, blurred vision, dizziness, hypotension and tinnitus. Symptoms of overdose in children are dry mouth, fixed dilated pupils, flushing, gastrointestinal symptoms and hyperthermia.
Synopsis
| Drug | : | Dexchlorpheniramine |
| Pharmacological Category | : | Antihistamines |
| Therapeutic Indication | : | Allergic conditions |
| Dosage Forms | : | Tablet, Syrup |
More Information
- Keep DIOMINIC TABLET out of reach of children
- Store DIOMINIC TABLET at a temperature below 25°C
FAQs About DIOMINIC TABLET
What is DIOMINIC TABLET and why is it prescribed?
DIOMINIC TABLET contains Dexchlorpheniramine which belongs to the group of medicines called Antihistamines. It is used to manage perennial, seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, mild uncomplicated allergic skin manifestations of urticaria and angioedema (swelling underneath skin).
Can DIOMINIC TABLET make me feel drowsy?
DIOMINIC TABLET may cause dizziness or drowsiness in some individuals. Do not drive or handle any machines if you experience drowsiness after taking DIOMINIC TABLET.
Is it safe to use DIOMINIC TABLET in pregnant women?
DIOMINIC TABLET should be used during the first two trimesters of pregnancy only if clearly needed. DIOMINIC TABLET is not recommended for use in the third trimester of pregnancy because newborn and premature infants may have severe reactions to antihistamines.
Should DIOMINIC TABLET be taken with food?
Take DIOMINIC TABLET as advised by your doctor. It can be taken before or after food. Try to take your dose of DIOMINIC TABLET at same time each day as it will make it easier for you to remember taking your medicine.
Can DIOMINIC TABLET be given to children?
DIOMINIC TABLET is not recommended to use in children under 2 years of age due to the risk of respiratory depression. Caution should be exercised when administering DIOMINIC TABLET to paediatric patients 2 years of age and older. Consult with your child’s doctor before giving DIOMINIC TABLET to your child.
References
1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Schwinghammer, Cecily V. DiPiro. Allergic rhinitis. Pharmacotherapy Handbook. Eighth Edition. 2011. 1655.
2. Dexchlorpheniramine. NIH National Library of Medicine, National Centre for Biotechnology Information. Pubchem. [Accessed on 3rd December 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Dexchlorpheniramine
3. J.K. Aronson. Dexchlorpheniramine. Science Direct. [Accessed on 3rd December 2022]. https://www.sciencedirect.com/topics/neuroscience/dexchlorpheniramine
4. Bayer New Zealand Limited. [Revised in February 2020] [Accessed on 3rd December 2022]. https://www.medsafe.govt.nz/profs/datasheet/p/Polaraminetabreptabsyrup.pdf
5. Bayer Australia Limited. NPS medicine wise. [Revised in November 2019] [Accessed on 3rd December 2022]. https://www.nps.org.au/medicine-finder/polaramine-tablets#full-pi
6. Yash Pharma Laboratories Pvt. Ltd. DexCPM-SR (Dexchlorpheniramine). [Accessed on 3rd December 2022]. http://yashpharma.com/product-details/dexcpm-sr/
Useful Diagnostic Tests
- Absolute Eosinophil Count
- Peripheral Smear Examination
- Total IgE
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