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Introduction About DILZEM SR TABLET
DILZEM SR TABLET contains Diltiazem which belongs to the group of medicines called Calcium Channel Blockers. It is used to manage angina and hypertension. It also manages you from getting chest pain in future.
During management with DILZEM SR TABLET your doctor will constantly monitor your kidney functions, blood pressure and blood sugar levels to avoid the risk of unwanted side effects. Avoid eating grapefruit or drinking grapefruit juice while taking DILZEM SR TABLET as it may severely decrease your blood pressure.
Before taking DILZEM SR TABLET inform your doctor if you have any liver, kidney or heart problems apart from angina and hypertension. You must also inform your doctor if you have diabetes, asthma, stomach problems or any form of mental illness as a precaution.
DILZEM SR TABLET is not suitable for use in pregnant women as it may cause serious harm to the growing baby. It is also not recommended for use in patients with heart failure, severe low blood pressure, problems in blood circulation or if you are a breastfeeding woman.
The most common side effects of taking DILZEM SR TABLET are nausea, indigestion, constipation, dizziness and swollen ankles. Contact your doctor if any of these side effect worsens.
Uses Of DILZEM SR TABLET
- Manage hypertension (high blood pressure)
- Manage and manages angina (chest pain)
How DILZEM SR TABLET Works
DILZEM SR TABLET is a calcium channel blocker. It relaxes the blood vessels by blocking the entry of certain ions (calcium ions) within them that causes narrowing. This allows blood to flow more smoothly across the blood vessels. It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.
How to use DILZEM SR TABLET
Take DILZEM SR TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not chew or crush the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not stop taking DILZEM SR TABLET without consulting your doctor.
Side Effects Of DILZEM SR TABLET
Common
- headache, dizziness
- swelling of the fingers, ankles, feet (edema)
- constipation, indigestion, stomach pain, nausea
Uncommon
- feeling dizzy while standing up or changing posture
Rare
- dry mouth
- lumpy, red, itchy skin
Stop taking DILZEM SR TABLET and contact your doctor immediately if you experience any of the following side effects such as:
- signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
- difficulty in breathing or worsening of asthma
- severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane, skin lesions with a pink/red ring and a pale center which may be itchy, scaly or filled with fluid)
- fast, slow or uneven heart rate
- signs of heart failure (such as shortness of breath with chest pain and swollen ankles)
- unusual body movements, facial muscle spasms, rolling eyes, feeling shaky
- signs of liver problems (fever, tiredness, loss of appetite, stomach pain, nausea)
- signs of high blood sugar levels (such as excessive thirst, passing more urine than normal and dryness of skin or mouth)
- skin sensitivity towards sunlight
- breast enlargement in men
How To Manage Side Effects
Constipation
Try to eat more fiber rich foods such as fresh fruit, vegetables and cereals. Drink plenty of water and exercise regularly. If this does not help, consult your doctor for advice.
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take DILZEM SR TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedDILZEM SR TABLET is not recommended for use in pregnant women and in women who think that they might be pregnant. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedDILZEM SR TABLET may pass through breast milk. Therefore, it is not recommended for use in breastfeeding women. However, consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if you experience dizziness or tiredness after taking DILZEM SR TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking DILZEM SR TABLET as it may make you feel dizzier.
Kidney
Use with CautionDILZEM SR TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
Use with CautionDILZEM SR TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take DILZEM SR TABLET if you are allergic to Diltiazem.
Lungs
Use with CautionDILZEM SR TABLET should be used with caution in patients with a previous history of asthma. Therefore, consult your doctor before taking it.
Heart Disease
Consult your doctorDILZEM SR TABLET is not recommended for use in patients with serious heart problems (such as having a very slow or uneven heartbeat or heart failure). It should be used with caution in patients with a previous history of heart failure, shortness of breath, slow heartbeat or low blood pressure. Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedDILZEM SR TABLET is generally not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.
Use In Geriatrics
Use with CautionDILZEM SR TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.
Others
DILZEM SR TABLET is not recommended for use if you:
- have problems in blood circulation especially to the lungs
Before taking DILZEM SR TABLET, inform your doctor if you:
- have any surgery in the upcoming days
- have depression
- have any mental illness that causes mood changes
- have any stomach problems
- have diabetes
- have porphyria (an inherited blood disorder)
Interactions
A. Drug-Drug Interactions:
Before taking DILZEM SR TABLET, inform your doctor, if you are taking any of the following medicines such as:
- digoxin, amiodarone, ivabradine (medicines used to manage abnormal heart rhythm)
- dantrolene (a medicine used to manage muscle spasms)
- lomitapide (a medicine used to control blood cholesterol levels)
- asunaprevir (a medicine used to manage Hepatitis C infection)
- medicines used to manage high blood pressure (such as doxazosin, tamsulosin, atenolol, propranolol or acebutolol)
- medicines used to manage angina (such as glyceryl trinitrate or isosorbide trinitrate)
- medicines used to manage high blood cholesterol levels (Ex. simvastatin, fluvastatin and atorvastatin)
- ciclosporin (a medicine used to suppress the body's immune function)
- phenytoin, carbamazepine (medicines used to manage epilepsy)
- medicines used to manage blood clots (Ex. aspirin, clopidogrel)
- iodinated contrast media (used during X-rays)
- theophylline (a medicine used to manage asthma)
- lithium (a medicine used to manage mental problems)
- benzodiazepines (medicines used to manage anxiety) Ex. midazolam, triazolam
- methylprednisolone (a steroid medicine used to manage allergies and inflammation)
- cilostazol (a medicine used to manage leg cramps)
- rifampicin (a medicine used to manage tuberculosis)
- cimetidine, ranitidine (medicines used for stomach ulcers)
B. Drug-Food Interactions:
Avoid drinking grapefruit juice while taking DILZEM SR TABLET as it may increase the risk of side effects.
Overdosage:
If you or anyone else accidentally took more DILZEM SR TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include severe hypotension (low blood pressure) leading to dizziness, fainting, slow heartbeat and changes in heart rhythm.
Synopsis
| Drug | : | Diltiazem |
| Pharmacological Category | : | Calcium channel blocker |
| Therapeutic Indication | : | Hypertension, Angina |
| Dosage Forms | : | Tablet, Capsule, Injection, Topical gel |
More Information
Storage
- Keep DILZEM SR TABLET out of reach of children
- Store DILZEM SR TABLET at room temperature
FAQs About DILZEM SR TABLET
Q: What DILZEM SR TABLET is used for?
A: DILZEM SR TABLET is used to manage angina and hypertension. It also manages you from getting chest pain in future.
Q: How DILZEM SR TABLET works on my body?
A: DILZEM SR TABLET is a calcium channel blocker. It relaxes the blood vessels by blocking the entry of certain ions (calcium ions) within them that causes narrowing. This allows blood to flow more smoothly across the blood vessels. It also reduces the strain on the heart and helps the heart to pump blood more efficiently with less pressure.
Q: What are the side effects of DILZEM SR TABLET?
A: The most common side effects of taking DILZEM SR TABLET are nausea, indigestion, constipation, dizziness and swollen ankles. Contact your doctor if any of these side effect worsens.
Q: Is DILZEM SR TABLET safe to use in children?
A: DILZEM SR TABLET is generally not recommended for use in children and adolescents (aged below 18 years). However, consult your doctor before taking it.
Q: Can DILZEM SR TABLET be taken by pregnant women?
A: DILZEM SR TABLET is not recommended for use in pregnant women or in women who might be expecting to get pregnant as it may cause serious harm to the growing baby. However, consult your doctor for advice.
Q: What to do if I forgot to take a dose of DILZEM SR TABLET?
A: If you forgot to take a dose of DILZEM SR TABLET, take it as soon as you remember. However, if it is time for the next dose of DILZEM SR TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of DILZEM SR TABLET to compensate the missed ones.
Q: Will taking a higher dose of DILZEM SR TABLET be more effective?
A: No, taking a higher dose of DILZEM SR TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can DILZEM SR TABLET cause constipation?
A: Yes. Constipation is a common side effect of using DILZEM SR TABLET. Eat plenty of fiber rich foods such as fresh fruits, vegetables, cereals as well as drink plenty of water and exercise more regularly when taking this medicine. Contact your doctor if this side effect bothers you.
Q: Can DILZEM SR TABLET cause dry mouth?
A: DILZEM SR TABLET rarely causes dryness of mouth. Contact your doctor if this side effect bothers you.
Q: What happens when I stop taking DILZEM SR TABLET?
A: Do not stop taking DILZEM SR TABLET without consulting your doctor as your blood pressure may raise once again. Make sure to take DILZEM SR TABLET for the stipulated duration recommended by your doctor to achieve maximum results.
Q: What is the best time to take DILZEM SR TABLET?
A: DILZEM SR TABLET can be taken with or without meals. Your doctor will decide the best time for you to take DILZEM SR TABLET based on your age, body weight and disease condition.
Q: Can I take DILZEM SR TABLET daily?
A: Take DILZEM SR TABLET as advised by your physician. Your doctor will evaluate your health condition and suggests whether can you take DILZEM SR TABLET every day or not.
Q: Is DILZEM SR TABLET safe to use in diabetic patients?
A: DILZEM SR TABLET may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking DILZEM SR TABLET as a precaution. Your doctor will closely monitor you blood sugar levels to avoid the risk of side effects.
Q: Can I stop taking DILZEM SR TABLET once my symptoms subside?
A: No. Do not stop taking DILZEM SR TABLET without consulting your doctor. As hypertension is a chronic condition, long term management may be necessary to control its symptoms. Therefore, take DILZEM SR TABLET as advised by your doctor for the stipulated duration. Stopping the therapy abruptly may increase your blood pressure once again.
Q: What precautions should be followed while taking DILZEM SR TABLET?
A: Before taking DILZEM SR TABLET inform your doctor if you have any liver, kidney or heart problems apart from angina and hypertension. You must also inform your doctor if you have diabetes, asthma, stomach problems or any form of mental illness as a precaution. Inform your doctor before taking DILZEM SR TABLET if you are pregnant or breastfeeding. Avoid drinking alcohol or grapefruit juice while taking DILZEM SR TABLET. Regularly visit your doctor and take all the necessary blood test recommended by your doctor without fail.
References
1. KD. Tripathi. Antihypertensive, Anti-arrhythmic, Antianginal. Essentials of medical pharmacology. Seventh edition. 2013. Page-546, 548.
2. Luis Rodríguez Padial, Gonzalo Barón-Esquivias, Antonio Hernández Madrid, Domingo Marzal Martín, Vicente Pallarés-Carratalá and Alejandro de la Sierra. Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2016. [Accessed on 2nd August 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4906086/
3. Sanofi Winthrop Industries. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 2nd August 2024] https://www.medicines.org.uk/emc/files/pil.4969.pdf
4. Bard Pharmaceuticals Limited. Electronic Medicines Compendium (EMC). [Revised in November 2020] [Accessed on 2nd August 2024] https://www.medicines.org.uk/emc/files/pil.1012.pdf
5. Sanofi Winthrop Industries. Electronic Medicines Compendium (EMC). [Revised in August 2021] [Accessed on 2nd August 2024] https://www.medicines.org.uk/emc/files/pil.1465.pdf
6. Accord. Electronic Medicines Compendium (EMC). [Revised in April 2022] [Accessed on 2nd August 2024] https://www.medicines.org.uk/emc/files/pil.5774.pdf
7. Bausch Health US LLC. Cardizem – Diltiazem Hydrochloride Tablet, coated. Dailymed.com. NIH. U.S. National Library of Medicine. [Revised in June 2020]. [Accessed on 2nd August 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f3e7ecef-f360-4987-a4f5-933214130ab2
8. DILTIAZEM HYDROCHLORIDE TABLETS IP 80MG (CARDISEC) TAJ PHARMA. [Accessed on 2nd August 2024] https://tajpharma.in/portfolio-item/diltiazem-hydrochloride-tablets-ip-80mg-cardisec-taj-pharma/
Useful Diagnostic Tests
- Kidney function test
- Liver function test
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