Dilzem CD 90mg Capsule 10'S

Introduction About DILZEM CD 90MG CAPSULE

Dilzem CD 90mg capsule is a calcium channel blocker widely used to manage cardiovascular conditions such as hypertension (high blood pressure), angina (heart-related chest pain), and certain types of irregular heart rhythms (arrhythmias). By relaxing and widening blood vessels, it improves blood flow and reduces the workload on the heart, which helps lower blood pressure and ease chest pain. The medication plays a crucial role in preventing complications related to high blood pressure, like strokes or heart attacks, and supports overall heart health.

It is ideal for patients diagnosed with high blood pressure or angina who require a medication to control their symptoms in conjunction with lifestyle changes such as a healthy diet and regular exercise. It may also be prescribed for patients experiencing abnormal heart rhythms. It is not typically recommended for people with heart block, severe heart failure, or those allergic to diltiazem. Pregnant or breastfeeding women should use this medication only under strict medical supervision due to limited safety data.

The capsule should be taken once daily at the same time, with or without food, as prescribed by a healthcare professional. It must be swallowed whole without crushing or chewing to maintain its extended-release mechanism. Patients are advised not to stop the medication abruptly, as this may worsen their condition. Consistency in dosing supports stable heart function and optimal blood pressure control.

Important precautions include monitoring for side effects such as dizziness, headache, nausea, or swelling, which usually improve over time but should be reported if persistent. Patients should avoid alcohol as it can increase side effects like dizziness or low blood pressure. Those with liver or kidney issues should inform their doctor for careful dose adjustments. Use during pregnancy and breastfeeding requires medical consultation. Following these directions and cautionary advice helps ensure the safe and effective use of Dilzem CD 90mg capsule for cardiovascular support.

Uses Of DILZEM CD 90MG CAPSULE

• Manage hypertension (high blood pressure)
• Manage angina (chest pain)

Benefits of DILZEM CD 90MG CAPSULE

Dilzem CD 90mg for Cardiovascular Support

Dilzem CD 90mg capsule supports cardiovascular health by relaxing blood vessels and improving blood flow throughout the body. It reduces the pressure against which the heart pumps, making it easier for the heart to work efficiently. This helps to maintain a healthier blood pressure level and reduces strain on the heart, promoting overall cardiovascular wellness. The medication’s ability to relax vascular smooth muscle also helps prevent episodes of vessel constriction, allowing better oxygen supply to tissues.

Dilzem CD 90mg for Angina Support

Dilzem CD 90mg is often prescribed to support individuals experiencing angina, a type of chest discomfort caused by reduced blood flow to the heart muscle. By dilating the coronary arteries, it enhances oxygen delivery to the heart tissue and decreases the heart’s oxygen demand by slowing the heart rate and lowering blood pressure. These effects help improve exercise capacity and reduce the frequency and severity of angina episodes, thereby supporting a more active lifestyle.

Dilzem CD 90mg for Heart Rhythm Regulation

In certain heart rhythm disturbances, Dilzem CD 90mg helps regulate and normalize the heartbeat. It acts on the cardiac conduction system, particularly by slowing conduction through the atrioventricular node, which helps control rapid or irregular heartbeats. This rhythm regulation reduces the workload on the heart and prevents symptoms like palpitations or dizziness associated with arrhythmias.

Dilzem CD 90mg for Blood pressure Regulation

Dilzem CD 90mg serves as an effective capsule for managing high blood pressure (hypertension). By relaxing the smooth muscles in artery walls, it lowers peripheral vascular resistance and decreases blood pressure. This not only supports heart function, but also reduces risks associated with prolonged high blood pressure such as stroke, heart attack, and kidney disease, helping maintain safer and healthier blood pressure levels.

How DILZEM CD 90MG CAPSULE Works

Dilzem CD 90mg Mechanism of Action

Dilzem CD 90mg works by blocking L-type calcium channels in the muscle cells of the heart and blood vessels. Calcium ions play a crucial role in muscle contraction; by limiting calcium entry, Dilzem relaxes the vascular smooth muscles, causing blood vessels to widen. This reduces the pressure against which the heart pumps, lowering blood pressure and decreasing cardiac workload. It also slows electrical conduction through the heart’s atrioventricular node, helping to regulate heart rate and rhythm. Together, these actions reduce myocardial oxygen demand and improve blood flow.

Blood Vessel Dilation Mechanism

Dilzem CD induces blood vessel dilation by relaxing the smooth muscle lining the arteries. This occurs because the drug inhibits calcium influx required for muscle contraction. As the muscles relax, the arteries widen or dilate, decreasing resistance to blood flow. The dilation allows blood to circulate more freely and reduces the load on the heart. This vasodilation effect occurs in both coronary arteries supplying the heart and systemic arteries throughout the body, contributing to lowered blood pressure and enhanced oxygen delivery.

Heart Rate Regulation by Dilzem

Dilzem CD influences heart rate by acting on the heart’s electrical conduction system, particularly the atrioventricular (AV) node. It slows down the passage of electrical impulses through the AV node, which results in a slower, more regular heartbeat. This helps control arrhythmias like supraventricular tachycardia and reduces the heart’s workload. By lowering the heart rate along with dilating blood vessels, Dilzem decreases myocardial oxygen consumption and supports better heart efficiency and patient symptoms.

How to use DILZEM CD 90MG CAPSULE

How to Take Dilzem CD 90

• Take Dilzem CD 90 exactly as prescribed by your healthcare provider.
• Usually taken once daily, often at the same time each day, such as in the morning or evening.
• Swallow the capsule whole with water; do not crush, chew, or break it.
• Can be taken with or without food but be consistent with your choice to maintain steady drug levels.
• Do not skip doses or stop taking the medication without consulting your doctor first.
• Follow doctor’s instructions on duration and any dosage adjustments needed.
• Avoid alcohol, driving, or operating heavy machinery if dizziness or drowsiness occurs.

Dilzem CD 90mg Dosage Instructions

• The typical starting dose ranges from 120 mg to 240 mg once daily depending on your condition.
• Dosage may be gradually increased by your doctor based on response, usually within 120 mg to 360 mg daily.
• For some cases, doses up to 540 mg daily may be prescribed, but only under close medical supervision.
• Extended-release capsule formulation ensures steady release over 24 hours for consistent effect.
• Dosage varies for different conditions such as hypertension, angina, or arrhythmias; follow doctor’s prescription.
• Always follow medical advice to avoid side effects and optimize therapeutic benefits.

What if I forgot to take DILZEM CD 90MG CAPSULE

• If you miss a dose of Dilzem CD 90 capsule, take it as soon as you remember.
• If it is almost time for your next scheduled dose, skip the missed dose to avoid doubling up.
• Never take two doses at the same time to make up for a missed dose.
• Resuming your regular dosing schedule is important for steady blood levels and effectiveness.
• Missing several doses in a row may reduce the medicine’s effect, so inform your doctor if this happens.
• Do not stop taking the medication abruptly without consulting your healthcare provider as this may worsen your condition.
• Always discuss any concerns or missed doses with your doctor or pharmacist for personalized advice.

Overdose

If you or someone else accidentally takes more than the recommended dose of Dilzem CD 90 mg capsule, seek medical attention immediately or visit the nearest hospital. Signs of overdose may include severe dizziness, very slow or irregular heartbeat, fainting, and difficulty breathing.

Side Effects Of DILZEM CD 90MG CAPSULE

Common side effects of Dilzem CD 90mg Capsule

• headache
• dizziness
• swelling of the fingers, ankles, feet (edema)
• constipation
•  indigestion
• stomach pain
• Flushing (feeling hot)
• Rash or Skin irritation
• Palpitations (Awareness of heartbeat)
•  nausea

When to Seek Medical Attention?

Stop taking this CAPSULE and contact your doctor immediately if you experience any of the following side effects such as:

• signs of allergic reactions (such as skin rash, swelling of the face, lips, mouth or throat which can lead to difficulty in breathing or swallowing)
• difficulty in breathing or worsening of asthma
• severe skin reactions (such as skin rash with itching and redness, blistering and peeling of skin, skin swelling and inflammation of mucous membrane, skin lesions with a pink/red ring and a pale centre which may be itchy, scaly or filled with fluid)
• fast, slow or uneven heart rate
• signs of heart failure (such as shortness of breath with chest pain and swollen ankles)
• unusual body movements, facial muscle spasms, rolling eyes, feeling shaky
• signs of liver problems (fever, tiredness, loss of appetite, stomach pain, nausea)
• signs of high blood sugar levels (such as excessive thirst, passing more urine than normal and dryness of skin or mouth)
• skin sensitivity towards sunlight
• breast enlargement in men

How To Manage Side Effects

Constipation

• Increase Fiber Intake: Eat more fruits, vegetables, whole grains, beans, and nuts which help add bulk to stool and stimulate bowel movements.
• Drink Plenty of Water: Staying hydrated softens stools and helps them pass more easily. Aim for at least 8 glasses a day.
• Regular Exercise: Physical activity stimulates intestinal function and promotes regular bowel movements. Even a daily walk can help.
• Prune Juice or Dried Prunes: These are rich in fibre and sorbitol, which can naturally relieve constipation by drawing water into the bowels.
• Olive Oil: Taking a teaspoon of olive oil on an empty stomach can act as a lubricant for the digestive system, easing stool passage.
• Warm Lemon Water: Drinking warm water mixed with fresh lemon juice in the morning can stimulate digestion and bowel movements.
• Establish a Routine: Try to have a bowel movement at the same time each day, preferably after meals, to train your body.
• Avoid Processed Foods: Limit intake of foods low in fibre such as fast food, processed snacks, and excessive dairy which may worsen constipation.
• Probiotic Foods: Yogurt, kefir, and fermented foods like sauerkraut contain beneficial bacteria that support gut health and improve stool consistency.

Warning & Precautions

Pregnancy

Contraindicated

It is not recommended for pregnant women or for those who suspect they may be pregnant. Always consult your doctor before using this medicine. 

Breastfeeding

Contraindicated

Since this can pass into breast milk, it is generally not advised for breastfeeding mothers. Seek medical advice before use.

Driving and Using Machines

Use with Caution

If you experience dizziness or fatigue after taking this capsule, avoid driving, using machinery, or performing tasks that require alertness.

Alcohol

Contraindicated

Do not consume alcohol while taking this medication, as it may increase dizziness and reduce alertness.

Kidney

Use with Caution

Patients with kidney problems should use with caution. Consult your doctor before starting the treatment.

Liver

Use with Caution

Caution is required in patients with liver disorders. Always take medical advice before using this medicine.

Allergy

Contraindicated

Do not take this if you are allergic to diltiazem or any of its ingredients.

Lungs

Use with Caution

Patients with a history of asthma should use this medicine carefully and only under medical supervision.

Heart Disease

Consult your doctor

It is not advised for people with serious heart problems, such as a very slow or irregular heartbeat or heart failure. It should also be used with caution in those with a history of low blood pressure, heart failure, a slow heart rate, or shortness of breath. Always consult your doctor before starting treatment. 

Use In Pediatrics

Contraindicated

This is generally not recommended for individuals below 18 years of age. Always consult your doctor before its use in this age group.

Use In Geriatrics

Use with Caution

Elderly patients (65 years and above) should take this with caution, as they may be more sensitive to its effects. Consult your doctor before starting treatment.

Other Warnings for DILZEM CD 90MG CAPSULE

Before taking this medicine, inform your doctor if you:

• have any surgery in the upcoming days
• have depression
• have any mental illness that causes mood changes
• have any stomach problems
• have diabetes
• have porphyria (an inherited blood disorder)

Who should not take [GBNKEYWORD

It is not recommended for use if you:

• have problems in blood circulation especially to the lungs

Safety Advice

• Always take Dilzem CD 90 mg capsule exactly as prescribed by your doctor.
• Take the medicine at the same time every day to maintain consistent blood levels.
• Monitor your blood pressure and heart rate regularly as advised by your healthcare provider.
• Inform your doctor if you have a history of low blood pressure, heart rhythm disorders, or heart failure before starting this medicine.
• Avoid sudden discontinuation; stop the medication only under medical supervision to prevent blood pressure spikes.
• Use caution if you are elderly or have liver or kidney problems, as dose adjustments may be required.
• Limit caffeine intake, as they can interfere with the effectiveness of the medicine.
• Check with your doctor before combining it with other blood pressure, heart, or anti-arrhythmic medications to avoid drug interactions.
• Report unusual symptoms like extreme dizziness, slow heartbeat, swelling in feet, or difficulty breathing immediately to your doctor.

Diet and Lifestyle Advice

• Follow a balanced, low-salt diet to support better blood pressure management.
• Include fresh fruits, vegetables, whole grains, and lean proteins in your meals.
• Limit foods high in saturated fats and cholesterol, such as fried or processed foods, to support heart health.
• Avoid excessive caffeine as they can affect blood pressure and heart rhythm.
• Stay hydrated by drinking enough water unless otherwise advised by your doctor.
• Engage in regular physical activity such as walking, yoga, or light exercises for at least 30 minutes a day, if approved by your physician.
• Maintain a healthy weight to enhance the effectiveness of your medication and reduce strain on your heart.
• Practice stress management techniques like meditation, breathing exercises, or mindfulness to help control blood pressure.
• Avoid smoking or tobacco products, as they increase the risk of heart-related complications.
• Keep a consistent medication routine along with healthy habits to maintain stable blood pressure levels.
• Monitor your blood pressure and pulse at home if recommended and share the readings with your doctor during follow-up visits.
• Limit high-sodium packaged foods and opt for freshly cooked, low-salt meals whenever possible.

1. Dilzem CD 90mg and Diltiazem 90mg SR tablets:

2. Dilzem CD 90 mg vs Dicard 90 mg SR tablets for hypertension:

Drug - Drug interaction

1. Beta-Blockers (e.g., Metoprolol, Atenolol, Propranolol)

• Interaction: Can increase the risk of slow heart rate (bradycardia) and low blood pressure due to overlapping effects on the heart.
• Management: Use with caution and under close medical supervision. Doctor may adjust doses and monitor heart rate regularly.

2. Other Calcium Channel Blockers (e.g., Amlodipine)

• Interaction: Increased blood concentration of these drugs can cause exaggerated effects like excessive lowering of blood pressure or heart rate.
• Management: Monitor for side effects such as dizziness or swelling; dose adjustments might be needed.

3. Digoxin

• Interaction: Dilzem may increase digoxin levels, which can lead to toxic effects.
• Management: Regular monitoring of digoxin blood levels and symptoms of toxicity is advised. Dose adjustment may be necessary.

4. Cyclosporine

• Interaction: Dilzem can raise cyclosporine blood levels, increasing toxicity risk.
• Management: Frequent blood tests to monitor cyclosporine levels; doctors may reduce cyclosporine dose.

5. Carbamazepine

• Interaction: Carbamazepine can reduce the effectiveness of Dilzem by increasing its metabolism.
• Management: Dosages might need adjustment; always inform the doctor if using carbamazepine.

6. Benzodiazepines (e.g., Diazepam, Clonazepam)

• Interaction: Levels of benzodiazepines can be increased, causing enhanced sedation or drowsiness.
• Management: Use caution with sedative effects; monitor patient closely.

7. Statins (e.g., Atorvastatin, Lovastatin)

• Interaction: Dilzem can increase statin blood levels, raising the risk of muscle-related side effects.
• Management: Monitor for muscle pain or weakness; dose modifications may be necessary.

8. Rifampin

• Interaction: Rifampin may decrease Dilzem blood levels, reducing its effectiveness.
• Management: Dose adjustments might be required; doctor will monitor response.

9. Ivabradine and Quinidine

• Interaction: Combining with Dilzem may increase the risk of abnormal heart rhythms.
• Management: Careful monitoring and ECG evaluations by healthcare provider recommended.

10. Flibanserin and Lomitapide

• Interaction: Levels can be significantly increased, potentially causing serious side effects.
• Management: Concurrent use generally contraindicated; alternative therapies should be considered.

Drug - Food interaction

1. Grapefruit and Grapefruit Juice

• Interaction: Grapefruit juice can increase blood levels of Dilzem CD by inhibiting its metabolism. This may lead to increased side effects like dizziness, low blood pressure, or heart rhythm problems.
• Management: Avoid consuming grapefruit products while taking Dilzem CD 90mg. Consult your healthcare provider for alternatives or advice.

2. Caffeine

• Interaction: No direct interaction, but caffeine-containing products can raise heart rate or blood pressure, which might counteract Dilzem's effects.
• Management: Moderate caffeine intake is generally safe; consult a doctor for personalized advice.

3. High-Fat Meals

• Interaction: High-fat meals may alter the absorption rate of the medication slightly but are not known to cause major issues.
• Management: Maintain a balanced diet; take the capsule consistently at the same time daily to maintain steady medicine levels.

4. Other Foods or Dietary Supplements

• Interaction: Some herbal supplements such as St. John's Wort may affect metabolism of medications like Dilzem CD.
• Management: Always inform your healthcare provider about any supplements or herbal products to avoid unexpected interactions.

Synopsis

More Information

FAQs About DILZEM CD 90MG CAPSULE

References

1. KD. Tripathi. Antihypertensive, Anti-arrhythmic, Antianginal. Essentials of medical pharmacology. Seventh edition. 2013. Page – 546, 548. 

2. Luis Rodríguez Padial, Gonzalo Barón-Esquivias, Antonio Hernández Madrid, Domingo Marzal Martín, Vicente Pallarés-Carratalá and Alejandro de la Sierra. Clinical Experience with Diltiazem in the Treatment of Cardiovascular Diseases. NCBI; PMC US National Library of Medicine, National Institute of Health. [Revised in June 2016]. [Accessed on 1st September 2025] 

4. Bausch Health US LLC. Cardizem – Diltiazem Hydrochloride Tablet, coated. Dailymed.com. NIH. U.S. National Library of Medicine. [Revised in 20th April 2025]. [Accessed on 1st September 2025] 

5. DILTIAZEM HYDROCHLORIDE TABLETS IP 80MG (CARDISEC) TAJ PHARMA. [Accessed on 2nd November 2022] 

Useful Diagnostic Tests

• Kidney function test
• Liver function test

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Thamada Manikanta Praveen - MBBS, MD (General Medicine)

Last updated on 02 Sep 2025 | 01:06 PM(IST)