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Introduction About DELCON 2/5MG SYRUP

DELCON 2/5MG SYRUP is a combination of Phenylephrine and Chlorpheniramine which belongs to the group of medicines called Nasal decongestants and Antihistamines respectively. It is used to relieve nasal and sinus congestion, allergic symptoms of the nose or throat due to upper respiratory tract allergies, sinus pain and headache. Also, it is used adjunctly with antibacterials to manage sinusitis (inflammation of the tissue lining the sinuses), tonsillitis (inflammation of the tonsils) and otitis media (middle ear infection).

Before giving DELCON 2/5MG SYRUP to your child, inform child’s doctor if your child has kidney, liver or heart problems, diabetes, fits or severely raised blood pressure. DELCON 2/5MG SYRUP is not recommended for use in pregnant or breast-feeding women and elderly patients as it is used only in children.

The most common side effects of DELCON 2/5MG SYRUP are nausea, vomiting, dry mouth, dizziness and tiredness. Consult your child’s doctor if any of the side effects worsen.

Uses Of DELCON 2/5MG SYRUP

It is used to:

relieve nasal and sinus congestion
relieves allergic symptoms of the nose or throat due to upper respiratory tract allergies
relieves sinus pain and headache
adjunctly with antibacterials to manage sinusitis, tonsillitis and otitis media

How DELCON 2/5MG SYRUP Works

DELCON 2/5MG SYRUP relieves cold symptoms where Phenylephrine decreases nasal congestion by acting on α1-adrenergic receptors in the small vessels of the nasal mucosa to produce constriction, resulting in decreased swelling and increased drainage of the sinus cavities and Chlorpheniramine binds to the histamine H1 receptor and blocks its action, resulting in temporary relief of the negative symptoms (runny nose, sneezing, watery and itchy eyes) brought on by histamine.

How to use DELCON 2/5MG SYRUP

Give DELCON 2/5MG SYRUP to your child as advised by the physician. Shake well before use. Use a measuring cup to properly measure the dose. Your child’s doctor will decide the correct dose and duration of DELCON 2/5MG SYRUP for your child depending upon child’s age, body weight and disease condition.

Side Effects Of DELCON 2/5MG SYRUP

Common

drowsiness
sedation
disturbance in concentrating, un-coordination, dizziness, headache
blurred vision
nausea or vomiting
dry mouth
tiredness

Rare

fear, anxiety, restlessness
tremor, weakness
painful urination

Stop giving DELCON 2/5MG SYRUP to your child and contact doctor immediately if your child experiences any of the following side effects:

develop rash, hives, itching, red or swollen or blistered or peeling skin; wheezing, tightness in the chest or throat, trouble breathing, swallowing or talking, unusual hoarseness or swelling of the mouth, face lips, tongue or throat

How To Manage Side Effects

Dry Mouth

Tell your child to sip water regularly and other sugar free liquids. Tell your child not to use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Consult child’s doctor if the symptom does not improve.

Headache

DELCON 2/5MG SYRUP is not recommended for use in elderly patients as it is used only in children. Consult your doctor for advice.

Others

DELCON 2/5MG SYRUP is not recommended for use if your child:

has phaeochromocytoma (rare tumours that start in the inner part of the adrenal gland)
has peripheral or mesenteric vascular thrombosis (blood clots usually in legs or major veins (one or more) that drain blood from the intestine

Before giving DELCON 2/5MG SYRUP to your child, inform your physician if your child:

has diabetes
has overactive thyroid
has closed angle glaucoma
has history of fits

Interactions

A. Drug-Drug interactions:

Before giving DELCON 2/5MG SYRUP to your child, inform to child’s doctor if your child is taking or receiving any of the following medicines:

ephedrine (used to manage low blood pressure)
phenytoin (used to manage epilepsy)
digoxin (used to manage irregular heartbeat)

Overdosage:

If your child accidentally takes too much of DELCON 2/5MG SYRUP, contact your doctor immediately or visit a nearby hospital. Overdosage symptoms of DELCON 2/5MG SYRUP includes extreme sleepiness, confusion, weakness, ringing in the ears, blurred vision, large pupils, dry mouth, flushing, fever or possibly seizures.

Synopsis

Drug	:	Phenylephrine, Chlorpheniramine
Pharmacological Category	:	Nasal decongestant, Antihistamines
Therapeutic Indication	:	Relieves nasal and sinus congestion, Allergic symptoms, sinus pain, sinusitis, tonsillitis and otitis media
Dosage Forms	:	Capsule, Tablet, Syrup, Oral drops

More Information

Storage

Keep DELCON 2/5MG SYRUP out of reach of children
Store at room temperature

FAQs About DELCON 2/5MG SYRUP

Q: What if I forget to give a dose of DELCON 2/5MG SYRUP to my child?

A: If you forget to give a dose of DELCON 2/5MG SYRUP to your child, give it as soon as you remember. However, omit the missed dose if it is almost time for the next one. Do not give the medicine two times to make up for the forgotten dose.

Q: Can I stop giving DELCON 2/5MG SYRUP to my child if the symptoms subside?

A: Continue giving DELCON 2/5MG SYRUP to your child until your child’s doctor tells you to stop, unless your experience child’s any unwanted effects, worsening of the condition or any new symptoms. In such cases, contact your child’s doctor right away.

Q: What precautions do I need to follow while giving DELCON 2/5MG SYRUP to my child?

A: Before giving DELCON 2/5MG SYRUP to your child, you must inform child’s doctor about their pre-existing conditions like any kidney, liver, heart or thyroid problems, diabetes, fits or severely raised blood pressure and any other allergies. Consult your child’s doctor if your child experiences anything different.

Q: Can I give other medicines to my child along with DELCON 2/5MG SYRUP?

A: Before giving DELCON 2/5MG SYRUP to your child, inform your child’s doctor if your child is taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicines, as these might interact with each other and cause serious side effects.

Q: Can DELCON 2/5MG SYRUP be used in children with liver problems?

A: DELCON 2/5MG SYRUP should be used with caution in children with liver impairment. Child’s doctor may monitor your child’s liver function before and during management with this medicine to manage the risk of any unusual effects. Consult your child’s doctor for advice before administration of DELCON 2/5MG SYRUP to your child.

References

1. Barbara G. Wells, Joseph T. DiPiro, Terry L. Shwinghammer, Cecily V. DiPiro. Allergic Rhinitis. Pharmacotherapy Handbook. Ninth edition. Page-813.

2. KD. Tripathi. Adrenergic System and Drugs. Essentials of Medical Pharmacology. Seventh edition. 2013. Page-135.

3. Mayuresh Kiran and Lalit Pawaskar. Study of Safety and Efficacy for the Combination of Chlorpheniramine maleate and Phenylephrine in Infants suffering from Allergic Rhinitis and Associated Symptoms. International Research of Contemporary Medical Research. March 2019. [Accessed on 20th July 2022] https://www.ijcmr.com/uploads/7/7/4/6/77464738/ijcmr_2406_v1.pdf

4. PubChem Compound Summary for CID 2725, Chlorpheniramine. National Center for Biotechnology Information. June 2022. [Accessed on 20th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine#section=Mechanism-of-Action

5. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops (Phenylephrine + Chlorpheniramine). [Revised in January 2022] [Accessed on 20th July 2022] https://www.centaurpharma.com/downloads/2022/pediatrics/cold/Sinarest%20AF%20oral%20drops.pdf

6. Centaur Pharmaceuticals Pvt. Ltd. and Lab Daffodil. Sinarest AF Drops/Syrups [Accessed on 20th July 2022] https://www.centaurpharma.com/downloads/Sinarest-AF-Syr-Drops2018.pdf

7. Zuventus Healthcare Limited. Maxtra Syrup (Phenylephrine + Chlorpheniramine maleate). [Accessed on 20th July 2022] http://www.zuventus.co.in/doctor_wise_products_selected.aspx?Medi_Id=149

8. GlaxoSmithKline Consumer Healthcare. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 20th July 2022] https://www.medicines.org.uk/emc/files/pil.3928.pdf

Useful Diagnostic Tests

Nasal cytology

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)

Last updated on 13 Aug 2024 | 09:58 AM(IST)

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