Dec 100mg Tablet 10'S

INTRODUCTION

DEC 100MG TABLET is a combination of Chlorpheniramine and Diethylcarbamazine which belongs to the group of medicines called Antiallergics and Filaricides respectively. It is indicated in the treatment of filariasis, tropical pulmonary eosinophilia and loa-loa (eye worm).  

Filariasis is a parasitic disease which affects the lymphatic system of the body and tropical pulmonary eosinophilia a clinical manifestation of filariasis in which these parasites reach the lung tissues.

Prior to the treatment with DEC 100MG TABLET your doctor might ask you to undergo several diagnostic tests to understand the existing condition.

DEC 100MG TABLET is not recommended for use in patients having heart or kidney disease and have a history of river blindness (onchocerciasis) involving the eyes. DEC 100MG TABLET should be used with caution in patients having liver or lung diseases, epilepsy, very high blood pressure and increased pressure in the eye.

DEC 100MG TABLET is not recommended for use in pregnant and breast-feeding women. Caution must be exercised while using the medicine in children and not recommended for use in elderly patients especially those with heart or kidney disease.

The most common side effects of taking DEC 100MG TABLET are nausea, dry mouth, headache, dizziness or tiredness. Ask for your doctor’s advice if any of these worsen or doesn’t improve.

USES OF DEC 100MG TABLET

Treats,

• filariasis
• tropical pulmonary eosinophilia
• loa-loa

HOW DEC 100MG TABLET WORKS

DEC 100MG TABLET helps in treating parasitic infections where Chlorpheniramine is an H1 Antihistamine which acts by blocking certain chemical substances in the body called histamine which is responsible for allergic symptoms. Diethylcarbamazine is a Filaricide which is thought to destroy the microfilariae (parasites) and also activate the immune system to further kill the parasites.

DIRECTIONS FOR USE

Take DEC 100MG TABLET as advised by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, condition and body weight.

SIDE EFFECTS OF DEC 100MG TABLET

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Take this medicine with or just after a meal or a snack and stick to simple meals and do not eat oil rich, fried or spicy food. Consult your doctor if the symptom does not improve.

Headache:

Try to take rest and don’t involve yourself in exertive activities. Apply a pain-relieving balm on your forehead if necessary.  Consult your doctor if the symptom does not improve.

Dry mouth:

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

WARNING & PRECAUTIONS

PREGNANCY

DEC 100MG TABLET is not recommended for use in pregnant women as it is not known if DEC 100MG TABLET affects the developing baby. Consult your doctor before taking it.

BREASTFEEDING

DEC 100MG TABLET is not recommended for use in breastfeeding women as it is not known if DEC 100MG TABLET passes through mother’s milk. Consult your doctor before taking it.

DRIVING AND USING MACHINES

Do not drive or operate any machines if you feel drowsy and sleepy after taking DEC 100MG TABLET.

ALCOHOL

Avoid the use of alcohol while taking DEC 100MG TABLET as it may cause drowsiness and increased effects of alcohol.

KIDNEY

DEC 100MG TABLET is not recommended for use in patients with kidney problems. Consult your doctor before taking it.  

LIVER

DEC 100MG TABLET should be used with caution in patients having liver disease. Consult your doctor before taking it.

ALLERGY

Do not take DEC 100MG TABLET if you are allergic to Chlorpheniramine or Diethylcarbamazine.

LUNGS

DEC 100MG TABLET should be used with caution in patients having asthma or other chest diseases. Consult your doctor before taking it.

HEART DISEASE

DEC 100MG TABLET is not recommended for use in patients with heart problems. Consult your doctor before taking it.

INTERACTIONS

A. Drug – Drug Interactions:

Before taking DEC 100MG TABLET, inform your doctor if you are taking any of the following medicines:

• monoamine oxidase inhibitors (MAOIs) such as isocarboxazid (used to treat depression)
• alprazolam, clonazepam (used to treat anxiety)
• psychotropic drugs such as escitalopram, sertraline (change the perception or behaviour)
• atropine (used to dilate the pupils, treat low heart rate in emergencies)
• phenytoin (used to treat epilepsy)

Overdosage:

If you or anyone else accidentally take too much of DEC 100MG TABLET, consult your doctor immediately or visit the nearby hospital. The symptoms of overdosage are nausea, vomiting, headache, vertigo, drowsiness and convulsions (fits).

SYNOPSIS

MORE INFORMATION

• Keep DEC 100MG TABLET out of reach of children
• Store at room temperature

FAQs ABOUT DEC 100MG TABLET

What is DEC 100MG TABLET and why is it prescribed?

DEC 100MG TABLET is a combination of Chlorpheniramine and Diethylcarbamazine which belongs to the group of medicines called Antiallergics and Filaricides respectively. It is indicated in the treatment of filariasis, tropical pulmonary eosinophilia and loa-loa (eye worm).

Can DEC 100MG TABLET impair my ability to drive?

DEC 100MG TABLET can cause drowsiness. Do not drive or operate any machines if you feel drowsy and sleepy after taking DEC 100MG TABLET. You can resume with activities as soon as you feel normal again.

Is DEC 100MG TABLET safe for children?

DEC 100MG TABLET is not recommended for use in children under 2 years of age. It should be used with caution in children as they may experience more side effects relating to the nervous system (such as mind, nerves, muscles and the senses). Consult your child’s doctor for advice.

Can DEC 100MG TABLET be given to pregnant and breast-feeding women?

DEC 100MG TABLET is not recommended for use in pregnant and breast-feeding women as it is not known if DEC 100MG TABLET affects the developing baby or passes through the breast milk. Consult with your doctor before taking it.

Who should not take DEC 100MG TABLET?

DEC 100MG TABLET is not recommended for use in patients having heart or kidney disease and have a history of river blindness (onchocerciasis) involving the eyes. Ask for your doctor’s advice before taking this medicine.

REFERENCES

1. K.D. Tripathi. Respiratory System Drugs, Antimicrobial Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 220 & 690.

2. Chlorpheniramine. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Accessed on 6th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Chlorpheniramine

3. Diethylcarbamazine. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Accessed on 6th July 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Diethylcarbamazine

4. Torrent Pharmaceuticals. Unicarbazan Forte (Diethylcarbamazine Citrate and Chlorpheniramine Maleate) Tablets. [Revised in July 2019] [Accessed on 6th July 2022] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2826.pdf

5. Finecure Pharmaceuticals Ltd. Flary Forte (Diethylcarbamazine Citrate and Chlorpheniramine Maleate) Tablets. [Accessed on 6th July 2022] https://www.finecurepharma.com/product/flary-forte/

6. Sapco Laboratories (P) ltd. Dicar Forte (Diethylcarbamazine Citrate and Chlorpheniramine Maleate) Tablets. [Accessed on 6th July 2022] http://www.sapcolaboratories.com/productsearch.asp

USEFUL DIAGNOSTIC TESTS

• Blood smear

AUTHOR DETAILS

Written By Dr. R. Dinesh John Rajkumar, Pharm.D
Last updated on 12 Dec 2022 | 06:20 PM(IST)