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Introduction About COVATIL 250MG INJECTION
COVATIL 250MG INJECTION is an antibiotic medicine used in the management of various bacterial infections such as infections of the respiratory tract, throat infections, skin infections, ear infections, sinus infections, lung infections, urinary tract infections, gynecological infections, blood infections, etc. It can also be used as a prophylactic therapy for reducing infection risks post-surgery.
It contains a medicine called Cefuroxime which is a powerful antibiotic agent that works by killing the susceptible organism that causes infection.
COVATIL 250MG INJECTION should be used under medical supervision. Usually, it is prescribed for 7-10 days to attain better control on infection. Therefore, do not stop taking this medicine or skip doses, as it may make this medicine less effective.
Before receiving COVATIL 250MG INJECTION, inform your doctor if you have kidney problems. You must also inform your doctor if you are allergic to any antibiotics, have fungal infections, previously experienced anaemia or diarrhoea after taking antibiotics, scheduled for any blood tests, or if you are pregnant or breastfeeding.
The most common side effect of receiving this medicine is pain at the injection site, swelling and redness. Consult your doctor immediately if any of the above symptoms worsen.
Uses Of COVATIL 250MG INJECTION
COVATIL 250MG INJECTION is used in the management of severe bacterial infections such as:
- Respiratory tract infections (such as bronchitis, infected bronchiectasis, bacterial pneumonia)
- Ear, nose and throat infections (such as sinusitis, tonsillitis, pharyngitis and otitis media)
- Urinary tract infections
- Skin and soft tissue infections, Wound infections
- Bone and joint infections
- Gynaecological infections
- Blood infections
- Infection of outer covering of the brain
- Post surgical infections
How COVATIL 250MG INJECTION Works
COVATIL 250MG INJECTION contains Cefuroxime which is a second-generation cephalosporin that interferes with the synthesis of the bacterial cell wall by binding to specific binding proteins located inside the bacterial cell wall. This leads to breaking down the cell wall of the bacteria and reducing its stability, thus causing cell damage, and eventually causing bacterial elimination.
How to use COVATIL 250MG INJECTION
COVATIL 250MG INJECTION will be given to you only by a doctor or nurse by intramuscularly (into a muscle) or intravenously (into the vein). Your doctor will administer the correct dose for you depending upon your age, body weight and severity of infection.
Side Effects Of COVATIL 250MG INJECTION
Common Side Effects of COVATIL 250MG INJECTION:
- pain (injection site), swelling and redness along a vein
- increase in liver enzyme
- changes in white blood cells (neutropenia or eosinophilia)
- low levels of red blood cells (anemia)
- high temperature
- sore throat
- skin rashes, urticaria (itchy red wheals), pruritus (bumpy rash)
- gastrointestinal disturbances
- diarrhoea, nausea
- increase in bilirubin (a substance produced by the liver)
- positive coomb’s test
Stop receiving COVATIL 250MG INJECTION and consult your doctor immediately if you experience any of the following side effects
- fungal infections
- severe diarrhoea (Pseudomembranous colitis), causing severe diarrhoea, usually with blood and mucus, stomach pain, and fever
Warning & Precautions
Pregnancy
Consult your doctorThe safety of Cefuroxime during pregnancy has not been clearly established. Therefore, your doctor will advise you to use COVATIL 250MG INJECTION after analysing the risks and benefits of the therapy.
Breastfeeding
Use with CautionCOVATIL 250MG INJECTION should be used with caution during breastfeeding as it may pass into the breast milk.
Driving and Using Machines
Use with CautionDo not drive or operate heavy machines if you feel dizziness after receiving COVATIL 250MG INJECTION.
Kidney
Use with CautionCOVATIL 250MG INJECTION should be used with caution in patients with a history of kidney problems.
Liver
Use with CautionCOVATIL 250MG INJECTION should be used with caution in patients with a history of liver problems.
Allergy
ContraindicatedDo not receive COVATIL 250MG INJECTION if you are allergic (hypersensitive) to Cefuroxime, cephalosporin, penicillin, monobactams, carbapenems or to any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedCOVATIL 250MG INJECTION should be used in children aged below 18 years only if advised by the physician. Your doctor will administer the right dose depends on your child’s age, body weight and severity of the infection.
Use In Geriatrics
Use with CautionCOVATIL 250MG INJECTION should be used with caution in elderly patients suffering kidney problems. Consult your doctor before receiving.
Others
COVATIL 250MG INJECTION is not recommended if you have:
- severe persistent diarrhoea along with sickness
Before receiving COVATIL 250MG INJECTION inform your doctor if you:
- have gastrointestinal disorder (diarrhoea)
- have fungal infection
Interactions
A. Drug-Drug interactions:
Before receiving COVATIL 250MG INJECTION, inform your doctor if you are receiving any of the following medicine:
- Other antibiotics (Ex. gentamycin)
- Diuretics (Ex. furosemide)
- Anti-gout agents (Ex. probenecid)
- Oral anticoagulants (Ex. warfarin)
- Birth control pills (Ex. ethinyl estradiol)
Overdosage:
It is unlikely to receive overdose since it will be administered by the doctor or nurse. If you experience any unusual side effects, consult your doctor immediately.
Synopsis
| Drug | : |
Cefuroxime |
| Pharmacological Category | : |
Cephalosporin Antibiotics |
| Therapeutic Indication | : |
Manages Bacterial infections |
| Dosage Forms | : |
Tablet, Injection, Capsule, Syrup, Dry Suspension, Drops, Dispersible tablet |
More Information
Storage
- Keep out of reach of children
- Store at room temperature
FAQs About COVATIL 250MG INJECTION
Q: What is COVATIL 250MG INJECTION used for?
A: It is used to manage bacterial infections such as lower respiratory tract infections, meningitis, septicemia, abdominal infections, urinary tract infections, skin and soft tissue infections, ear, nose and throat infections, obstetric and gynecological infections, bone, joint infections and gonorrhea. COVATIL 250MG INJECTION is also used to manage infections, before and after surgery.
Q: Can I take oral contraceptive pills while receiving COVATIL 250MG INJECTION?
A: No, COVATIL 250MG INJECTION may interact with birth control pills and lowers its efficiency. So, you should tell your doctor if you are using any birth control pills.
Q: Can COVATIL 250MG INJECTION be given to breastfeeding mothers?
A: COVATIL 250MG INJECTION should be used with caution as it may pass into the breast milk. Consult your doctor before receiving. It should only be given if the expected benefits outweigh any potential risk to the baby.
Q: Can COVATIL 250MG INJECTION cause diarrhoea?
A: Yes, COVATIL 250MG INJECTION may cause serious diarrhea during or after use. Usually, discontinuation of medicine can subside diarrhea. However, if diarrhea persists or if there is blood in the stool then immediately consult your doctor.
Q: In what condition COVATIL 250MG INJECTION should be avoided?
A: Before receiving COVATIL 250MG INJECTION tell your doctor if you have a history of serious anaphylactic reaction to cefuroxime or any other cephalosporin antibiotics.
References
1. KD Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. Seventh Edition,2013. Page - 727.
2. Gold B, Rodriguez WJ. Cefuroxime: mechanisms of action, antimicrobial activity, pharmacokinetics, clinical applications, adverse reactions and therapeutic indications. National Library of Medicine. PubMed Central (PMC). [Accessed on 7th September 2022] click here
3. GlaxoSmithKline Manufacturing S.P.A. [Revised in July 2014] [Accessed on 7th September 2022] click here
4. Acs Dobfar S.P.A. The Electronic Medicines Compendium (Emc). [Revised in May 2022] [Accessed on 7th September 2022] click here
5. Villerton Invest SA. The Electronic Medicines Compendium (emc). [Revised in May 2021] [Accessed on 7th September 2022] click here
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6. Hikma Pharmaceuticals USA Inc. [Revised in May 2021] [Accessed on 7th September 2022] click here
7. Acs Dobfar Spa. [Revised in May 2021] [Accessed on 7th September 2022] click here
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