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Introduction About COSCOPIN BR SYRUP
COSCOPIN BR SYRUP contains Ambroxol, Ammonium chloride, Chlorpheniramine maleate, Guaifenesin, and Phenylephrine which belongs to the group of medicines called mucolytic agents, expectorants, antihistamines, expectorants, nasal decongestant respectively. It is used in adults and children above 12 years for the management of coughs and colds.
The symptoms involve a running nose, a blocked or stuffed nose, throat pain, sneezing, watering and itching eyes, sinusitis (congestion, pressure, and pain in the sinuses), etc. COSCOPIN BR SYRUP can also be used to relieve symptoms of redness, itching, and swelling of the skin associated with seasonal allergies, insect bites, and food allergies due to the presence of the chlorpheniramine ingredient in it.
Before taking COSCOPIN BR SYRUP, inform your doctor if you have sugar intolerance, kidney or liver diseases, peptic ulcers, fits, heart diseases, glaucoma, bronchitis, difficulty passing urine, an overactive thyroid gland, diabetes, blood diseases, etc. to avoid the risk of unwanted side effects.
COSCOPIN BR SYRUP is not recommended for use if you are pregnant (especially in the first trimester), breastfeeding, or if you have children below the age of 12 or who have asthma. Except for medical advice.
The most common side effects of taking COSCOPIN BR SYRUP involve nausea, vomiting, headache, drowsiness, confusion, sleepiness, dry mouth, vision disturbances, skin rashes, etc. Consult your doctor if any of the symptoms are worsening.
Uses Of COSCOPIN BR SYRUP
It is used in adults and children above 12 years for the management of:
- cough
- cold (symptoms involve blocked or running nose, throat pain, stuffed nose, sneezing, watering from eyes, itching eyes etc)
- sinusitis (pressure, pain, and congestion in the sinus)
- allergy (seasonal allergy and food allergy)
- insect bite
How COSCOPIN BR SYRUP Works
COSCOPIN BR SYRUP contains ambroxol, guaifenesin, ammonium chloride, chlorpheniramine maleate, and phenylephrine. Ambroxol is a mucolytic agent that manages the excess secretion of mucus; thus, it lowers the phlegm's viscosity and makes it thin and easy to cough out.
Guaifenesin and ammonium chloride promotes mucus clearance and facilitate coughing up and spitting out the sputum. Phenylephrine is a nasal decongestant that helps to increase sinus cavity drainage and relieve nasal congestion. As a result, [GBBKEYWORD] aids in the relief of cough and cold symptoms.
How to use COSCOPIN BR SYRUP
Take COSCOPIN BR SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of COSCOPIN BR SYRUP
Common
- nausea
- altered taste
- numbness in throat and mouth
Uncommon
- vomiting
- loose motion
- digestive problems
- stomach pain
- dry mouth
Rare
- rashes
- hives/ urticaria
- hypersensitivity reactions
- weakness
- dryness in mouth
- constipation
- running nose
Stop taking COSCOPIN BR SYRUP and contact your doctor if you experience any of the following
- swelling in lips, mouth, face, and throat with difficulty in breathing, swallowing, and talking (symptoms of angioedema)
- increased heart rate, sweating, fall in blood pressure, difficulty standing up, loss of consciousness (symptoms of anaphylactic shock)
- dryness in the throat
- skin with rashes, blisters, pain along with fever (Steven–Johnson syndrome)
- occurrence of areas with redness and swelling on the body along with fever (skin condition called acute generalized exanthematous pustulosis)
- skin reaction with sores in mouth, throat, genitals, fever, headache etc (symptoms of erythema multiforme
- painful red area that spreads quickly, skin peels without blisters, fever, headache etc (symptoms of toxic epidermal necrolysis)
- nervousness, dizziness, or sleeplessness
- symptoms are not recovering after 7 days
- lesions in the inner lining of the mouth, throat, nose, and genitals
- yellowing of eyes and skin( signs of liver problems)
- hyperactivity in children and confusion in elderly
- difficulty concentrating, irritability, depression
- chest pain, poor muscle coordination, etc
How To Manage Side Effects
Diarrhea
Keep yourself hydrated by drinking plenty of fluids and electrolytes such as ORS. Consult a doctor before taking any medication.
Dry Mouth
Drink plenty of water to make your mouth moist every time. Chew sugar-free gums. Avoid alcohol consumption and cigarette smoking. Consult your doctor if it is worsening.
Headache
Drink plenty of fluids and stay hydrated. Try to be tension free and relaxed. Take adequate sleep and rest. Avoid consumption of alcohol. Apply pain balm if required. Consult your doctor if it is getting worsened.
Nausea And Vomiting
Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Keep yourself hydrated by drinking lots of fluids.
Warning & Precautions
Pregnancy
ContraindicatedCOSCOPIN BR SYRUP is not recommended if you are pregnant (especially in the first trimester) Consult your doctor before taking it.
Breastfeeding
ContraindicatedCOSCOPIN BR SYRUP is not recommended for breastfeeding mothers. Consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate machines while taking COSCOPIN BR SYRUP as it may make you drowsy or cause altered vision, attention problems, or altered visual-motor coordination. Consult a doctor before taking COSCOPIN BR SYRUP.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking COSCOPIN BR SYRUP as it may make you sleepier. Consult a doctor before taking it.
Kidney
Use with CautionCOSCOPIN BR SYRUP should be used with caution in patients suffering from kidney failure (impaired renal function) and in patients who are having difficulty passing urine due to enlarged prostate gland. Consult a doctor before taking COSCOPIN BR SYRUP.
Liver
Use with Caution[GBBKEYWORD] should be used with caution in patients diagnosed with severe liver diseases. Consult your doctor before taking COSCOPIN BR SYRUP.
Allergy
ContraindicatedDo not take COSCOPIN BR SYRUP if you are allergic to ambroxol, ammonium chloride, guaifenesin, chlorpheniramine maleate, phenylephrine, or any other ingredients in it. Consult your doctor before taking COSCOPIN BR SYRUP.
Lungs
Use with CautionCOSCOPIN BR SYRUP should be used with caution in patients suffering from respiratory diseases that result in the risk of mucus plug formation (bronchial motor diseases) like asthma, bronchiectasis, cystic fibrosis, etc. Consult your doctor before taking it.
Heart Disease
Use with CautionCOSCOPIN BR SYRUP should be used with caution in patients suffering from heart disease and high blood pressure. Consult your doctor before taking COSCOPIN BR SYRUP.
Use In Pediatrics
ContraindicatedCOSCOPIN BR SYRUP is not recommended to use in children below 12 years of age except on doctors’ advice. Consult your doctor before taking COSCOPIN BR SYRUP.
Use In Geriatrics
ContraindicatedCOSCOPIN BR SYRUP is not recommended to use in weak elderly patients due to the experience of serious side effects such as confusion. Consult a doctor before taking COSCOPIN BR SYRUP.
Others
Before taking COSCOPIN BR SYRUP inform your doctor if you are having:
- sensitivity to any food or medicine
- sugar intolerance
- diabetes
- thyroid diseases
- sodium-restricted diet
- ulcer in the stomach or intestine
- intestinal obstructions
- fits
- blood or circulatory diseases( ex. Porphyria)
- difficulty in passing urine
- enlarged prostate gland
- glaucoma
- planning to do urine tests as interaction with COSCOPIN BR SYRUP may give a false result
Interactions
A. Drug-Drug interactions:
Before using COSCOPIN BR SYRUP inform your doctor if you are taking the following medicines:
- medicines used to manage infections (ex. amoxicillin, cefuroxime, doxycycline, erythromycin)
- medicines used to manage cough (ex. pholcodine, diphenhydramine etc.)
- medicines used to manage depression (ex. tricyclic antidepressants such as nortriptyline, desipramine etc and monoamine oxidase inhibitors such as tranylcypromine, isocarboxacid etc)
- medicine used to manage heart problems (ex. atropine)
- medicines used to manage fits (ex. phenytoin)
- medicines used to get sleep and relaxation (ex. clonazepam, triazolam, zolpidem, barbiturates, diazepam etc)
- medicines used to relieve pain (ex. tramadol, methadone, paracetamol etc)
- medicines used to manage allergy (ex. antihistamines like diphenhydramine, cetirizine etc)
- any other herbal or homoeopathic medicines
Overdosage:
If you or anyone else accidentally took too more of this medicine, consult your doctor immediately. Symptoms include nausea, vomiting, feeling sick, and stomach pain.
Synopsis
| Drug | : | Ambroxol, Ammonium chloride, Chlorpheniramine maleate, Guaiphenesin, Phenylephrine |
| Pharmacological Category | : | Mucolytics, expectorants, antihistamines, expectorants, nasal decongestants |
| Therapeutic Indication | : |
Used to manage symptoms of cough, cold, and sinusitis. It can also be used to manage symptoms of allergies and insect bites |
| Dosage Forms | : | Syrup |
More Information
- Keep COSCOPIN BR SYRUP out of reach of children
- Store COSCOPIN BR SYRUP at room temperature
FAQs About COSCOPIN BR SYRUP
Q: What is COSCOPIN BR SYRUP used for?
A: COSCOPIN BR SYRUP is used in adults and children over 12 years old for the management of cough and cold. Symptoms involve a running nose, a blocked or stuffed nose, throat pain, sneezing, watering and itching eyes, sinusitis (congestion, pressure, and pain in the sinuses), etc.
COSCOPIN BR SYRUP can also be used to relieve symptoms of redness, itching, and swelling of the skin associated with seasonal allergies, insect bites, and food allergies due to the presence of the chlorpheniramine ingredient in it. Consult a doctor before taking COSCOPIN BR SYRUP.
Q: What are the side effects of taking COSCOPIN BR SYRUP?
A: Side effects of taking COSCOPIN BR SYRUP include nausea, vomiting, headache, drowsiness, confusion, sleepiness, dry mouth, vision disturbances, numbness in the throat and mouth, loose motions, constipation, skin rashes, etc. Consult your doctor if any of the symptoms are worsening while taking COSCOPIN BR SYRUP.
Q: How does COSCOPIN BR SYRUP work?
A: COSCOPIN BR SYRUP contains ambroxol, guaifenesin, ammonium chloride, chlorpheniramine maleate, and phenylephrine. Ambroxol thinks the mucus and makes it easier to cough out. Guaifenesin and ammonium chloride promotes mucus clearance and facilitate coughing up and spitting out the sputum. Phenylephrine helps to increase sinus cavity drainage and relieve nasal congestion. Thus, [GBBKEYWORD] helps relieve the symptoms of cough and cold.
Q: Can I give COSCOPIN BR SYRUP to manage the cough for a 2-year-old baby?
A: COSCOPIN BR SYRUP is not recommended to take in children below 12 years of age except on experts’ advice. Consult a doctor before taking COSCOPIN BR SYRUP.
Q: Can I drive a car or bike while taking COSCOPIN BR SYRUP?
A: Do not drive or operate any machines while taking COSCOPIN BR SYRUP as it may make you drowsy or cause altered vision, attention problems, or altered visual-motor coordination. Consult a doctor before taking COSCOPIN BR SYRUP.
References
1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology.8th edition. 2019. Page – 238, 240,242.
2. Evan Richards. Michael j. Lopez. Christopher V Maani. Phenylephrine. Richards, Evan, Michael J. Lopez, and Christopher V. Maani. Phenylephrine. In Stat Pearls [Internet]. StatPearls Publishing, 2021. [Revised on 11th July 2022] [Accessed on 1st September 2022] https://www.ncbi.nlm.nih.gov/books/NBK534801/
3. Tashiro, Manabu, Yumiko Sakurada, Hideki Mochizuki, Etsuo Horikawa, Masahiro Maruyama, Nobuyuki Okamura, Shoichi Watanuki, Hiroyuki Arai, Masatoshi Itoh, and Kazuhiko Yanai. Effects of a sedative antihistamine, d-chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving. Tashiro, Manabu, Yumiko Sakurada, Hideki Mochizuki, Etsuo Horikawa, Masahiro Maruyama, Nobuyuki Okamura, Shoichi Watanuki, Hiroyuki Arai, Masatoshi Itoh, and Kazuhiko Yanai. Effects of a sedative antihistamine, d-chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving. Human Psychopharmacology: Clinical and Experimental 23, no. 2 (2008). [Published on 8th January 2008] [Accessed on 1st September 2022] https://onlinelibrary.wiley.com/doi/abs/10.1002/hup.909
4. The Boots Company. Electronic Medicines Compendium (EMC). [Accessed on 1st September 2022] https://www.medicines.org.uk/emc/files/pil.3866.pdf
5. Reckitt Benckiser Health Care. Electronic Medicines Compendium (EMC). [Revised in March 2012] [Accessed on 1st September 2022] https://www.medicines.org.uk/emc/files/pil.616.pdf
6. Sandoz d.d. Estonian branch. Ambroxol. [Revised in June 2016] [Accessed on 1st September 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_10403_ENG.pdf
7. LABORATORIOS CINFA, S.A. Ambroxol. [Revised in May 2016] [Accessed on 1st September 2022] https://www.cinfainternational.com/wp-content/uploads/PIL_ambroxol_HK.pdf
8. Rotapharm. Ambroxol. [Accessed on 26th August 2022] http://www.rotapharm.co.uk/wp-content/uploads/Bronolac.pdf
9. Dailymed. Phenylephrine. [Revised in March 2022] [Accessed on 1st September 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d7d62ac1-1333-4366-884b-26537766ce38&type=display
10. Drug bank. Ammonium chloride. [Accessed on 1st September 2022] https://go.drugbank.com/drugs/DB06767
Useful Diagnostic Tests
- Blood examination
- Sputum culture
- Chest x-ray
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