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COLDNIL DS Suspension 60ml

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    Introduction About COLDNIL DS SUSPENSION

    COLDNIL DS SUSPENSION is used to relieve common cold symptoms such as blocked nose, runny nose, fever, watery eyes, sneezing, allergic rhinitis, and nasal congestion.

    It contains a combination of medicines called Cetirizine, Paracetamol, and Phenylephrine, which belong to the group of medicines called Anti-allergic, Analgesic & Antipyretic, Nasal, and decongestant, respectively.

    Cetirizine works by blocking histamine receptors in the body, reducing allergy symptoms like sneezing and itching. Paracetamol reduces pain and fever by inhibiting an enzyme in the brain that produces prostaglandins, which are chemicals that cause inflammation and pain. Phenylephrine acts as a decongestant by constricting blood vessels in the nasal passages, which helps to reduce swelling and congestion.

    The common cold is a viral infection that affects the nose and throat. Fever is generally increased body temperature in response to an infection. Avoid alcohol consumption while taking this medicine, as it leads to excessive drowsiness.

    Before taking COLDNIL DS SUSPENSION, inform your doctor if you have liver problems, kidney problems, convulsions, diabetes, or thyroid problems. It should be used with caution in pregnant women, and it is not recommended to use in breastfeeding women.

    The most common side effects of COLDNIL DS SUSPENSION are nausea, vomiting, sleepiness, and dizziness. Consult your doctor for advice if any of the above symptoms worsen.

    Uses Of COLDNIL DS SUSPENSION

    It is used to relieve common cold symptoms such as:

    • blocked nose
    • runny nose
    • fever
    • watery eyes
    • sneezing
    • allergic rhinitis
    • nasal congestion

    How COLDNIL DS SUSPENSION Works

    COLDNIL DS SUSPENSION is a combination of Cetirizine, Paracetamol, and Phenylephrine, where Cetirizine is an H1 receptor antagonist that works by blocking the action of a chemical messenger (histamine) responsible for runny nose, watery eyes, and sneezing. It also has anti-inflammatory action. Paracetamol is an analgesic and antipyretic that acts by inhibiting the synthesis of prostaglandins (chemicals that cause inflammation, pain, and fever), which helps in reducing pain and fever. Phenylephrine is a nasal decongestant that acts by narrowing the small blood vessels, providing temporary relief from congestion or stuffiness in the nose.

    How to use COLDNIL DS SUSPENSION

    • Take COLDNIL DS SUSPENSION as advised by your physician.
    • Shake well before use.
    • The dose and duration for you will be decided by your physician depending on your age, body weight, and disease condition.

    Side Effects Of COLDNIL DS SUSPENSION

    COMMON

    • nausea, vomiting
    • sleepiness
    • dizziness

    Warning & Precautions

    Pregnancy

    Use with Caution

    COLDNIL DS SUSPENSION should be used with caution in pregnant women. 

    Breastfeeding

    Contraindicated

    COLDNIL DS SUSPENSION is not recommended to use in breastfeeding women. 

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machines if you feel sleepy or drowsy after taking COLDNIL DS SUSPENSION.

    Alcohol

    Consult your doctor

    Avoid alcohol consumption while using COLDNIL DS SUSPENSION, as it leads to excessive drowsiness.

    Kidney

    Use with Caution

    COLDNIL DS SUSPENSION should be used with caution in patients with kidney problems. 

    Liver

    Use with Caution

    COLDNIL DS SUSPENSION should be used with caution in patients with liver problems. 

    Allergy

    Contraindicated

    Do not take COLDNIL DS SUSPENSION if you are allergic to cetirizine, paracetamol, and phenylephrine, or to any other ingredients of this medicine.

    Use In Pediatrics

    Use with Caution

    COLDNIL DS SUSPENSION should be used with caution in children and adolescents (2 years of age and above). 

    Use In Geriatrics

    Use with Caution

    COLDNIL DS SUSPENSION should be used with caution in elderly patients.

    Others

    Before taking COLDNIL DS SUSPENSION, inform your doctor if you have:

    • diabetes
    • thyroid problems
    • convulsions

    Interactions

    A. Drug-Drug interactions:

    Before taking COLDNIL DS SUSPENSION, inform your doctor if you are taking any of the following medicine:

    • medicines used to manage depression (Ex. isocarboxazid, phenelzine)
    • medicines used for colds, coughs, and sleeping (Ex. chlorpheniramine, diazepam, and opioids)
    • medicines used to manage epilepsy (Ex. phenobarbital, phenytoin, sodium valproate, primidone, and carbamazepine)
    • medicines used to manage HIV infections (Ex. zidovudine)
    • warfarin (a medicine used to manage blood clotting)
    • medicines used to manage nausea and vomiting (Ex. domperidone and metoclopramide)

    Overdosage:

    If you or anyone else accidentally takes too much of COLDNIL DS SUSPENSION or if you or a child accidentally swallow this medicine, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Cetirizine, Paracetamol, Phenylephrine
    Pharmacological Category :  

    Anti-allergic, Analgesic & Antipyretic, Nasal Decongestant

    Therapeutic Indication :   Relieves common cold symptoms
    Dosage Forms :   Tablet, Syrup, Suspension, Drops

    More Information

    Common Cold: A viral infection of the upper respiratory tract that causes symptoms like a blocked nose, runny nose, sneezing, sore throat, and mild fever.

    Allergic Rhinitis: Inflammation of the nasal passages triggered by allergens like pollen or dust, leading to symptoms such as sneezing, runny nose, itchy eyes, and nasal congestion.

    Nasal Congestion: Swelling of the nasal passages often caused by colds, allergies, or infections, resulting in difficulty breathing through the nose.

    Some lifestyle changes that will help the cold:

    FAQs About COLDNIL DS SUSPENSION

    Q: Does COLDNIL DS SUSPENSION cause drowsiness?

    A: Yes, the most common side effect of COLDNIL DS SUSPENSION is drowsiness. Caution should be exercised while driving or operating heavy machines. Do not drive or handle heavy machines if you experience side effects like dizziness or drowsiness while taking COLDNIL DS SUSPENSION. Consult your healthcare professional if the drowsiness does not improve.

    Q: Can I consume alcohol along with COLDNIL DS SUSPENSION?

    A: No, it is not advisable to drink alcohol while taking COLDNIL DS SUSPENSION. Consuming alcohol along with COLDNIL DS SUSPENSION may aggravate the symptoms of COLDNIL DS SUSPENSION and cause severe liver damage, dizziness, and drowsiness. Consult your doctor before using it.

    Q: Can we use COLDNIL DS SUSPENSION during pregnancy and breastfeeding?

    A: COLDNIL DS SUSPENSION should be used with caution in pregnant women, and it is not recommended for use in breastfeeding women. Consult your doctor before using it.

    Q: Is COLDNIL DS SUSPENSION an antibiotic?

    A: No, COLDNIL DS SUSPENSION is not an antibiotic. COLDNIL DS SUSPENSION is a combination of cetirizine, paracetamol, and phenylephrine, which belong to the group of medicines called anti-allergic, analgesic, antipyretic, and decongestant, respectively. It is used to relieve symptoms of the common cold, such as a blocked nose, runny nose, fever, headache, watery eyes and sneezing, allergic rhinitis, and nasal congestion. It does not manage bacterial infections.

    Q: What precautions are to be taken if I forget to take COLDNIL DS SUSPENSION?

    A: Before taking COLDNIL DS SUSPENSION, inform your doctor if you have diabetes, thyroid problems, fits, or occlusive vascular disease (Raynaud’s phenomenon).

    Q: What should I do if I forget to take a dose of COLDNIL DS SUSPENSION?

    A: If you forget to take a dose of COLDNIL DS SUSPENSION, take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and take the usual prescribed dose. Do not take a double dose for the missed dose.

    Q: Can I stop taking COLDNIL DS SUSPENSION if I feel better?

    A: Do not stop taking COLDNIL DS SUSPENSION, even though you feel better. Your symptoms may recur if you stop taking COLDNIL DS SUSPENSION. Inform your doctor before stopping it.

    Q: Can COLDNIL DS SUSPENSION cause diarrhea?

    A: Yes, COLDNIL DS SUSPENSION can cause diarrhea in some individuals. Drink lots of fluids, such as water or fruit juice, to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.

    Q: Can I take COLDNIL DS SUSPENSION during kidney disease?

    A: COLDNIL DS SUSPENSION should be used with caution in patients with kidney problems. Consult your doctor before taking it.

    Q: Can I take COLDNIL DS SUSPENSION during liver disease?

    A: COLDNIL DS SUSPENSION is not recommended in patients with severe hepatic dysfunction. It should be used with caution in patients with mild to moderate liver problems. Consult your doctor before taking it.

    Q: What are the side effects of taking COLDNIL DS SUSPENSION?

    A: The most common side effects of taking COLDNIL DS SUSPENSION are nausea, vomiting, fatigue, dry mouth, headache, abdominal pain, drowsiness, dizziness, and diarrhea. Consult your doctor if any of the side effects worsen.

    Q: Who should not take COLDNIL DS SUSPENSION?

    A: COLDNIL DS SUSPENSION is not recommended for use if you have severe liver disease, are allergic to cetirizine, paracetamol, and phenylephrine, or have coronary artery disease and severe hypertension. Consult your doctor before taking it.

    Q: How does COLDNIL DS SUSPENSION work?

    A: COLDNIL DS SUSPENSION is a combination of Cetirizine, Paracetamol, and Phenylephrine, where Cetirizine is an H1 receptor antagonist that works by blocking the action of a chemical messenger (histamine) responsible for runny noses, watery eyes, and sneezing. Paracetamol is an analgesic and antipyretic that acts by inhibiting the synthesis of prostaglandins (chemicals that cause inflammation, pain, and fever), which helps in reducing pain and fever. Phenylephrine is a nasal decongestant that acts by narrowing the small blood vessels, providing temporary relief from congestion or stuffiness in the nose.

    References

    1. KD. Tripathi Autacoids and Related Drugs, Adrenergic System and Drugs, Nonsteroidal Anti-inflammatory Drugs, and Antipyretic-Analgesics Essentials of Medical Pharmacology. Seventh edition. 2013. Pages-166, 135, 192.

    2. Aasim Naqvi; Valerie Gerriets. Cetirizine. NIH. National Library of Medicine. National Center for Biotechnology Information. Stat Pearls. November 2022. [Accessed on 10th October 2024] click here

    3. Samir S Ayoub. Paracetamol (acetaminophen): A familiar drug with an unexplained mechanism of action. The Journal of Temperature. February 2021. [Accessed on 10th October 2024] click here

    4. Evan Richards; Michael J. Lopez; Christopher V. Maani. Phenylephrine. NIH. National Library of Medicine. National Center for Biotechnology Information. Stat Pearls. July 2022. [Accessed on 10th October 2024] click here

    5. Phenylephrine. NIH. National Library of Medicine. [Accessed on 10th October 2024] click here

    6. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2022] [Accessed on 10th October 2024] click here

    7. Pinewood Laboratories Ltd. Electronic Medicines Compendium (EMC). [Revised in October 2020] [Accessed on 10th October 2024] click here

    8. Leeford. Cetirizine, Paracetamol, and Phenylephrine. [Accessed on 10th October 2024] click here

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    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)
    Last updated on 17 Oct 2024 | 03:11 PM(IST)
    Lab updated