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Introduction About COLDIMIX DS SUSPENSION
COLDIMIX DS SUSPENSION contains Chlorpheniramine maleate, Paracetamol, phenylephrine, and Sodium citrate which belong to the group of medicines called antihistamines, analgesics, nasal decongestants, and mucolytics respectively. It is used in children to manage and relieve symptoms of the common cold, cough, hay fever(seasonal allergy) and other respiratory conditions.
Symptoms of these diseases include a runny or blocked nose, sore throat, tonsillitis, sinus congestion, headache, fever, sinusitis, watering and itching of the eyes, sneezing, and middle ear infection (otitis media). COLDIMIX DS SUSPENSION is also used for the management of minor pains such as migraines, tooth pain, muscle aches, etc.
Before taking COLDIMIX DS SUSPENSION, inform your doctor if you are pregnant, breastfeeding, or have diseases like liver and kidney diseases, alcohol dependence, intolerance to any sugars, heart diseases, diabetes, thyroid disease, fit, closed-angle glaucoma (an eye disease with increased pressure inside the eyes that may lead to loss of vision), trouble urinating due to an enlarged prostate gland, etc.
COLDIMIX DS SUSPENSION is not recommended for use in patients with severe hypertension and asthma. COLDIMIX DS SUSPENSION should be used with caution in pregnant and breastfeeding women. COLDIMIX DS SUSPENSION should not be used in children under the age of four.
The most common side effects of taking COLDIMIX DS SUSPENSION include nausea, weakness, sedation, shaking, anxiety, difficulty sleeping, anxiety, tremor, etc. Consult your doctor if any of the symptoms are worsening.
Uses Of COLDIMIX DS SUSPENSION
Manages the symptoms of:
- common cold and hay fever (symptoms include includes red, itchy, watery eyes, sneezing, itchy nose, or throat, running nose or blocked nose, throat pain, dry cough etc.)
- cough
- sinusitis
- tonsilitis
- middle ear infection
- minor aches and pain such as tooth pain, back pain, mild arthritis (inflammation of joints), migraine
How COLDIMIX DS SUSPENSION Works
COLDIMIX DS SUSPENSION contains chlorpheniramine, paracetamol, phenylephrine, and sodium citrate. Chlorpheniramine is an antihistamine that blocks the effect of histamines (chemicals produced by the body in response to allergens) and manages the release of allergy-causing chemicals that are responsible for the symptoms of itching in the eyes, watery eyes, sneezing, running, or a blocked nose.
Paracetamol blocks chemical messengers in the brain that regulate pain and heat, thus helping to relieve fever and pain. Phenylephrine is a nasal decongestant that helps to increase sinus cavity drainage and relieve nasal congestion.
Sodium citrate is added to cough syrup as a mucolytic, which thins and loosens mucus, making it easier to cough out. Thus, COLDIMIX DS SUSPENSION helps to relieve the symptoms of a cold, cough, pain, and aches.
How to use COLDIMIX DS SUSPENSION
Take COLDIMIX DS SUSPENSION as advised by your physician. Shake well before use. COLDIMIX DS SUSPENSION is generally taken after food. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of COLDIMIX DS SUSPENSION
Rare
Stop taking COLDIMIX DS SUSPENSION and contact your doctor immediately if you have:
- swelling on face, lips, mouth, and throat with difficulty in swallowing, and breathing accompanied by rashes or hives in body
- becoming tired, getting cold often, bleeding more than usual
- redness of the skin with rashes and blisters
- nervousness, dizziness, or sleeplessness
- symptoms do not improve within 7 days or are accompanied by fever
Warning & Precautions
Pregnancy
Use with CautionCOLDIMIX DS SUSPENSION should be used with caution if you are pregnant or might be pregnant. A lower dose is generally recommended to use in pregnancy. Consult your doctor before taking it.
Breastfeeding
Use with CautionCOLDIMIX DS SUSPENSION should be used with caution if you are breastfeeding as there is a chance for COLDIMIX DS SUSPENSION to pass through breast milk. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Driving and Using Machines
Use with CautionDo not drive and operate any machines while taking COLDIMIX DS SUSPENSION as it can make you feel dizzier and drowsier. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Alcohol
ContraindicatedDo not consume alcohol while taking COLDIMIX DS SUSPENSION to avoid unwanted side effects. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Kidney
Use with CautionCOLDIMIX DS SUSPENSION should be used with caution in patients with kidney diseases. (Difficulty to pass urine) Consult your doctor before taking it.
Liver
ContraindicatedCOLDIMIX DS SUSPENSION is not recommended for patients diagnosed with serious liver diseases. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take COLDIMIX DS SUSPENSION if you are allergic to chlorpheniramine maleate, paracetamol, phenylephrine, or sodium citrate. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Lungs
Consult your doctorCOLDIMIX DS SUSPENSION is not recommended to be used in patients suffering from asthma. COLDIMIX DS SUSPENSION should be used with caution in patients suffering from other breathing problems like bronchitis, and bronchiectasis. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Heart Disease
Consult your doctorCOLDIMIX DS SUSPENSION is not recommended to take in patients suffering from increased blood pressure. COLDIMIX DS SUSPENSION should be used with caution in patients having heart diseases, consult your doctor before taking COLDIMIX DS SUSPENSION.
Use In Pediatrics
ContraindicatedCOLDIMIX DS SUSPENSION is not recommended to use take in children below 4 years of age. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Use In Geriatrics
Use with CautionCOLDIMIX DS SUSPENSION should be used with caution in elderly people as they are at a higher risk of getting side effects.
Others
COLDIMIX DS SUSPENSION is not recommended to take if you are having:
- sugar intolerance
- fits
Before taking COLDIMIX DS SUSPENSION inform your doctor if you have:
- allergy to any food or medicine
- diabetes
- closed-angle glaucoma
- thyroid diseases
- trouble in urinating due to enlarged prostate
- intestinal obstruction
- porphyria(blood disorder)
- sodium-restricted diet
Interactions
A. Drug-Drug interactions:
Before using COLDIMIX DS SUSPENSION inform your doctor if you are taking the following medicines:
- medicines used to manage psychiatric problems (ex. monoamine oxidase inhibitors such as tranylcypromine, isocarboxazid etc)
- medicines used to manage depression (ex. tricyclic antidepressants such as nortriptyline, desipramine etc)
- medicines used to manage high blood pressure(ex. methyldopa, reserpine, veratrum alkaloids )
- medicines that contain paracetamol as an ingredient (ex. medinol, disprol )
- medicine used to manage nausea and vomiting(ex. domperidone, metoclopramide)
- medicine used to manage blood clotting(ex. warfarin)
- medicines used to manage fits(ex.phenytoin, carbamazepine)
- medicines used to manage cholesterol(ex.cholestyramine)
- medicines used to manage pregnancy(ex. ethinylestradiol, norgestimate etc )
- medicines used to get sleep and relaxation (ex. clonazepam, triazolam, zolpidem etc)
- medicines used to relieve pain (ex. tramadol, methadone etc)
- medicines used to manage allergy (ex. antihistamines like diphenhydramine, cetirizine etc)
- medicine used to manage heart problems (ex. atropine)
Overdosage:
If you or anyone else accidentally took too more of this medicine, consult your doctor immediately. Symptoms include excitement, depression, restlessness, coma, respiratory disturbances etc.
Synopsis
| Drug | : | Chlorpheniramine maleate, Paracetamol, Phenylephrine, Sodium citrate |
| Pharmacological Category | : | Antihistamines, Analgesics, Nasal decongestants, Mucolytics |
| Therapeutic Indication | : | Used to manage symptoms of cold, cough, hay fever, sinusitis, tonsillitis, middle ear infection, minor pain and aches |
| Dosage Forms | : | Syrup |
More Information
- Keep COLDIMIX DS SUSPENSION out of reach of children
- Store COLDIMIX DS SUSPENSION at room temperature
FAQs About COLDIMIX DS SUSPENSION
Q: What is COLDIMIX DS SUSPENSION used for?
A: COLDIMIX DS SUSPENSION is used in children to manage and relieve symptoms of the common cold, cough, hay fever (seasonal allergy), and other respiratory conditions. Runny nose or blocked nose, sore throat, tonsillitis, sinus congestion, headache, fever, sinusitis, watering and itching in eyes, sneezing, and middle ear infection (otitis media) are all symptoms of these diseases.COLDIMIX DS SUSPENSION is also used for the management of minor pains such as migraines, tooth pain, muscle aches, etc. consult a doctor before taking COLDIMIX DS SUSPENSION.
Q: What are the most common side effects of taking COLDIMIX DS SUSPENSION?
A: The most common side effects of taking COLDIMIX DS SUSPENSION include nausea, weakness, sedation, shaking, anxiety, difficulty sleeping, anxiety, tremor, etc. Consult your doctor if any of the symptoms are worsening.
Q: How does COLDIMIX DS SUSPENSION work?
A: COLDIMIX DS SUSPENSION contains chlorpheniramine, paracetamol, phenylephrine, and sodium citrate. Chlorpheniramine is an antihistamine that blocks the effect of histamines (chemicals produced by the body in response to allergens) and manages the release of allergy-causing chemicals that are responsible for the symptoms of itching in the eyes, watery eyes, sneezing, running, or a blocked nose.
Paracetamol blocks chemical messengers in the brain that regulate pain and heat, thus helping to relieve fever and pain. Phenylephrine is a nasal decongestant that helps to increase sinus cavity drainage and relieve nasal congestion.
Sodium citrate is added to cough syrup as a mucolytic, which thins and loosens mucus, making it easier to cough out. Thus, COLDIMIX DS SUSPENSION helps to relieve the symptoms of a cold, cough, pain, and aches. Consult a doctor before taking COLDIMIX DS SUSPENSION.
Q: Can I consume alcohol while taking COLDIMIX DS SUSPENSION?
A: Do not consume alcohol while taking COLDIMIX DS SUSPENSION to avoid unwanted side effects. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Q: Can I drive a car or bike while taking COLDIMIX DS SUSPENSION?
A: Do not drive a car or bike while taking COLDIMIX DS SUSPENSION as it may make you dizzy and drowsier. Consult your doctor before taking COLDIMIX DS SUSPENSION.
Q: How do I take COLDIMIX DS SUSPENSION?
A: Take COLDIMIX DS SUSPENSION as advised by your physician. Shake well before use. COLDIMIX DS SUSPENSION is generally taken after food. Your doctor will determine the appropriate dose and duration for you based on your age, weight, and disease condition.
References
1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology.8th edition. 2019. Page – 148,223-24, 179-80.
2. Abdrhman Mahmoud Gamil. Gamil, Abdrhman Mahmoud. Development and validation of stability indicating method for determination of sodium citrate in pediatric cough syrup. Development and validation of stability indicating method for determination of sodium citrate in pediatric cough syrup. World Journal of Advanced Research and Reviews 8, no. 2 . 21st November 2020. [Accessed on 22nd August 2022] https://wjarr.com/content/development-and-validation-stability-indicating-method-determination-sodium-citrate
3. Graham, Garry G., and Kieran F. Scott. Mechanism of action of paracetamol.Graham, Garry G., and Kieran F. Scott. Mechanism of action of paracetamol. American journal of therapeutics 12, no. 1 (2005). [Accessed on 22nd August 2022] https://journals.lww.com/americantherapeutics/Abstract/2005/01000/Mechanism_of_Action_of_Paracetamol.8.aspx
4. The Boots Company PLC. Electronic Medicines Compendium (EMC) [Revised in April 2018] [Accessed on 22nd August 2022] https://www.medicines.org.uk/emc/files/pil.3866.pdf
5. Dailymed. Phenylephrine. [Revised on 1st March 2021] [Accessed on 22nd August 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4dfd46e4-b9f9-464d-aa47-e8fa9e526a5d
6. OTC Monograph final, Dailymed. Phenylephrine. [Revised in March 2022] [Accessed on 12th August 2022] https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d7d62ac1-1333-4366-884b-26537766ce38&type=display
7. Crescent manufactures. Paracetamol. [Revised in May 2019] [Accessed on 22nd August 2022] https://mhraproductsprod.blob.core.windows.net/docs/840c9bc10dfa7559674994c1b1d2ef9714000ae3
8. Sewel pharmaceuticals. Paracetamol. [Accessed on 22nd August 2022] https://www.coursehero.com/file/41098020/133-Packaging-Insertdocx/
9. Chlorpheneramine + Paracetamol + Phenylephrine + Sodium citrate. Centaur pharmaceuticals. [Revised in January 2021] [Accessed on 22nd August 2022] https://www.centaurpharma.com/downloads/2021/pediatrics/cold/Sinarest%20syrup.pdf
10. Chlorpheneramine + Paracetamol + Phenylephrine + Sodium citrate. Ronak Exim Private Limited. [Accessed on 22nd August 2022] https://fdaghana.gov.gh/img/smpc/Ronfit%20Cold-P%20Junior%20(Paracetamol+Phenylephrine%20Hcl).pdf
11. Chlorpheneramine + Paracetamol + Phenylephrine + Sodium citrate. Innovative pharma. [Accessed on 22nd August 2022] https://www.innovativepharma.in/product/mucobrex-pd-suspension/, https://www.innovativepharma.in/product/mucobrex-suspension/
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