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Introduction About COGNISTAR 60MG INJECTION
COGNISTAR 60MG INJECTION contains Cerebroprotein Hydrolysate which belongs to group of medicines called Neurotrophic agents. It is used to manage cranial injury, aprosexia (inability to concentrate) in dementia, cerebrovascular disease that includes stroke, and Alzheimer's disease.
A cranial injury is a head injury causing trauma to the scalp, skull, or brain. It is characterised by symptoms such as leakage of blood outside the blood vessels, uncontrolled bleeding, skull fracture, brain injury, or swelling in the brain.
A stroke occurs when the blood supply to the brain or part of it is blocked. It is characterised by symptoms such as troubled speech, numbness in the body, visual disturbances, headaches, and troubled waking.
Dementia is a group of symptoms such as loss of memory and thinking/reasoning abilities. Alzheimer’s disease is a disorder that causes progressive degeneration of brain cells, resulting in brain shrinkage. It is characterised by dementia, social withdrawal, and wandering.
COGNISTAR 60MG INJECTION is not recommended for use in patients with severe renal dysfunction, status epilepticus (a life-threatening neurological disorder), or major epilepsia (a seizure that causes loss of consciousness and violent muscle contractions).
COGNISTAR 60MG INJECTION should be used with caution in patients with epilepsy (fits or seizures) and or allergic diathesis (condition causing predisposition to develop group of allergies such as hay fever, allergic rhinitis, bronchial asthma, or atopic dermatitis).
COGNISTAR 60MG INJECTION should be used with caution in pregnant and breastfeeding females only if it is clearly needed. COGNISTAR 60MG INJECTION should be used with caution in elderly patients (above 65 years). Consult your doctor before receiving it.
The common side effects associated with the use of COGNISTAR 60MG INJECTION are headache, nausea, vertigo (sensation of spinning), increased sweating, agitation, fever, and hallucinations. Consult your doctor if any of the symptoms worsen.
Uses Of COGNISTAR 60MG INJECTION
- Manage cranial injury (head injury)
- Manage cerebrovascular disease that includes stroke (lack of blood supply in the brain)
- Manage aprosexia (inability to concentrate) in dementia
- Manage Alzheimer’s disease (disease caused due to degeneration of brain cells)
How COGNISTAR 60MG INJECTION Works
COGNISTAR 60MG INJECTION helps in restoring brain functions where Cerebroprotein Hydrolysate works by protecting nerve cells from toxins and lack of oxygen. It improves the survival ability of nerve cells. It also helps in the formation of new nerve cells, increasing nutrition of brain cells, reducing inflammation of brain tissues, and blocking the release of certain chemicals that may damage brain cells.
How to use COGNISTAR 60MG INJECTION
COGNISTAR 60MG INJECTION will be given to you only by a doctor or a nurse into the vein. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of COGNISTAR 60MG INJECTION
Common
- headache
- nausea
- vertigo (sensation of spinning)
- increased sweating
- agitation
- fever
- hallucinations
- confusion
- flu like symptoms such as chills, fever, sore throat, and coughing
- anxiety
Rare
- hyperventilation (deeper and faster breathing)
- high blood pressure
- fatigue (weakness)
- tremor
- depression
- indifference
- numbness
- deranged appetite
- digestive disorders
- diarrhoea
- constipation
- vomiting
- signs of allergic reaction such as itching, focal skin vascular reaction, pains in head, neck and extremities, fever, mild back pain, shortness of breath, tremor, or shock-like appearances
Stop receiving COGNISTAR 60MG INJECTION and contact your doctor if you experience any of the following side effects:
- arrhythmia or palpitation (faster heart rate)
How To Manage Side Effects
Constipation
Try to eat more high-fibre foods, such as fresh fruit, vegetables, and cereals, and drink plenty of water. Exercise regularly or go for a daily walk or run. If this does not help, inform your doctor about receiving alternate managements for constipation.
Diarrhea
Drink lots of fluids, such as water, to keep yourself hydrated. Try to avoid receiving any medicine on your own to manage diarrhoea, and consult your doctor if the symptom gets worse.
Headache
Take rest and drink plenty of water. Avoid receiving alcohol and skipping meals. Do not strain your eyes by watching the screen for a long time. Consult your doctor if the condition persists for a long time or gets worse.
Nausea And Vomiting
Try to take COGNISTAR 60MG INJECTION with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.
Warning & Precautions
Pregnancy
Monitoring requiredCOGNISTAR 60MG INJECTION should be used cautiously in pregnant females only if it is considered clearly necessary. Consult your doctor before receiving it.
Breastfeeding
Monitoring requiredCOGNISTAR 60MG INJECTION should be used cautiously in breastfeeding mothers only if it is considered clearly necessary. Consult your doctor before receiving it.
Driving and Using Machines
Consult your doctorDo not drive or operate machines after receiving COGNISTAR 60MG INJECTION to avoid any possible risk. Consult your doctor before receiving it.
Alcohol
Consult your doctorConsult your doctor before receiving COGNISTAR 60MG INJECTION if alcohol is planned to be consumed.
Kidney
Consult your doctorCOGNISTAR 60MG INJECTION is not recommended for use in patients with severe renal dysfunction. It should be used with caution in patients with other kidney problems. Consult your doctor before receiving it.
Liver
Use with CautionCOGNISTAR 60MG INJECTION should be used with caution in patients with liver disease. Consult your doctor before taking COGNISTAR 60MG INJECTION.
Allergy
ContraindicatedCOGNISTAR 60MG INJECTION is not recommended for use if you are allergic to cerebroprotein hydrolysate, or any other ingredients of this medicine. Consult your doctor before receiving it.
Use In Pediatrics
Use with CautionCOGNISTAR 60MG INJECTION should be used with caution in children. Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Use In Geriatrics
Use with CautionCOGNISTAR 60MG INJECTION should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Others
COGNISTAR 60MG INJECTION is not recommended for use if you:
- have status epilepticus (condition in which seizure that lasts for more than five minutes or there occurs more than one seizure in five minutes)
- have major epilepsy (seizure that causes loss of consciousness and violent muscle contractions)
Before receiving COGNISTAR 60MG INJECTION, inform your doctor if you:
- allergic diathesis (condition causing predisposition to develop group of allergies such as hay fever, allergic rhinitis, bronchial asthma, or atopic dermatitis)
- convulsion (repeated and uncontrolled contraction and relaxation of muscles)
- have or ever had any seizures (epilepsy or fits)
Interactions
A. Drug-Drug Interactions:
Before receiving COGNISTAR 60MG INJECTION, inform your doctor, if you are taking any of the following medicine:
- medicines used to manage depression such as mono-amineoxidase inhibitors (MAOIs) Ex. phenelzine
Overdosage:
COGNISTAR 60MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Cerebroprotein hydrolysate |
| Pharmacological Category | : | Neurotrophic agents |
| Therapeutic Indication | : | Cranial injury, Aprosexia (inability to concentrate) in dementia, Cerebrovascular disease including stroke, Alzheimer's disease |
| Dosage Forms | : | Injection, Tablet |
More Information
- Keep the medicine out of reach of children
- Store COGNISTAR 60MG INJECTION at room temperature
FAQs About COGNISTAR 60MG INJECTION
Q: What is COGNISTAR 60MG INJECTION used for?
A: COGNISTAR 60MG INJECTION is used to manage cranial injury, aprosexia (inability to concentrate) in dementia, cerebrovascular disease that includes stroke, and Alzheimer's disease. Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Q: What happens if you take more COGNISTAR 60MG INJECTION than your required dose?
A: COGNISTAR 60MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely that you will receive an overdose. However, if you experience any unusual symptoms, consult your doctor immediately or visit the nearby hospital.
Q: What side effects are seen with COGNISTAR 60MG INJECTION?
A: The common side effects associated with the use of COGNISTAR 60MG INJECTION are headache, nausea, vertigo (sensation of spinning), increased sweating, agitation, fever, and hallucinations. Consult your doctor if any of the symptoms worsen.
Q: Who should avoid receiving COGNISTAR 60MG INJECTION?
A: COGNISTAR 60MG INJECTION is not recommended for use in patients allergic to cerebroprotein hydrolysate or with severe renal dysfunction, status epilepticus (a life-threatening neurological disorder), or major epilepsia (a seizure that causes loss of consciousness and violent muscle contractions). Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Q: Is COGNISTAR 60MG INJECTION safe to use in elderly patients?
A: COGNISTAR 60MG INJECTION should be used with caution in elderly patients (aged 65 years and above), especially in those who do not respond to anticholinesterases. Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Q: How does COGNISTAR 60MG INJECTION work?
A: COGNISTAR 60MG INJECTION helps in restoring brain functions, where Cerebroprotein Hydrolysate works by protecting nerve cells from toxins and a lack of oxygen. It improves the survival ability of nerve cells. It also helps in the formation of new nerve cells, increases the nutrition of brain cells, reduces inflammation of brain tissues, and blocks the release of certain chemicals that may damage brain cells.
Q: Can I drive while receiving alcohol?
A: Do not drive vehicles, operate machines, or do any hazardous activity after receiving COGNISTAR 60MG INJECTION to avoid any possible risk as this medicine may cause vertigo. Consult your doctor before receiving COGNISTAR 60MG INJECTION.
Q: What is the method of receiving COGNISTAR 60MG INJECTION?
A: COGNISTAR 60MG INJECTION will be given to you only by a doctor or a nurse and placed into the vein. Your doctor will determine the correct dose and duration for you depending upon your age, body weight, and disease condition.
Q: What medication’s intake should be lowered while receiving COGNISTAR 60MG INJECTION?
A: Before receiving COGNISTAR 60MG INJECTION, inform your doctor if you are taking medicines that are used to manage depression, such as monoamine oxidase inhibitors (MAOIs), such as phenelzine.
Q: Can COGNISTAR 60MG INJECTION cause flu?
A: Yes. COGNISTAR 60MG INJECTION may cause flu-like symptoms such as fever, chills, sore throat, and cough in some patients, which are generally temporary and resolve with time. However, contact your doctor if this condition worsens.
References
1. Perry B. Molinoff. Neurotransmission and the Central Nervous System. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. Twelfth Edition. 2011. Page – 375.
2. Mosam Phirke, Avinash Desousa, Nilesh Shah, Sushma Sonavane, Anup Bharati. The use of cerebroprotein hydrolysate in dementia: A case series of 25 cases seen in a tertiary general hospital. Journal of geriatric mental health. 2014. [Accessed 7th July 2022] https://www.jgmh.org/article.asp?issn=2348-9995;year=2014;volume=1;issue=2;spage=106;epage=109;aulast=Phirke
3. Fanbing Kong, Hujie Song. Progress in Treatment of Spastic Cerebral Palsy with Integrated Traditional Chinese and Western Medicine. Clausius Scientific Press. MEDS Clinical Medicine. 2021. [Accessed 7th July 2022] http://clausiuspress.com/assets/default/article/2021/11/24/article_1637736393.pdf
4. Ciplamed. CEREBROCIP Injection (Cerebroprotein hydrolysate). [Revised in August 2017] [Accessed 7th July 2022] https://www.ciplamed.com/content/cerebrocip-injection
5. Medicrit Biotech Private Limited. Cerbocin 60 MG Injection. [Accessed 7th July 2022] https://www.medicrit.co.in/product/cerbocin-60mg-injection/
Useful Diagnostic Tests
- Computerized tomography (CT) scan
- Magnetic resonance imaging (MRI)
- Positron emission tomography (PET)
- Psychiatric evaluation
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