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Introduction About COFFDRYL SYRUP
COFFDRYL SYRUP is a combination of Ammonium Chloride, Diphenhydramine, Menthol, and Sodium Citrate which belongs to the group of medicines called Cough and Cold preparations. It is used to relieve allergy indications such as colds, hay fever, sneezing, coughing, itching, watery red eyes, runny and blocked nose.
COFFDRYL SYRUP is not recommended for use in patients with porphyria, persistent chronic cough (cough occurs with smoking, asthma, emphysema, or when the cough is accompanied by excessive secretions), epilepsy, glaucoma, and difficult urination. COFFDRYL SYRUP should be used with caution in patients with lung, heart, or liver diseases.
COFFDRYL SYRUP is not recommended for use among women who are pregnant and breastfeeding unless considered clearly necessary. Contact your doctor before taking. COFFDRYL SYRUP is not recommended for use in new born or premature infants and in children under 6 years of age. Contact your doctor before taking.
COFFDRYL SYRUP should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking. The most common side effects of taking COFFDRYL SYRUP are slight dry mouth, dizziness, headache, nausea, vomiting, and gastrointestinal discomfort. Contact your physician in case of worsening of the above symptoms.
Uses Of COFFDRYL SYRUP
It is used to relieve allergy symptoms such as:
- cold
- hay fever
- sneezing
- coughing
- itching
- watery red eyes
- runny or blocked nose
How COFFDRYL SYRUP Works
COFFDRYL SYRUP helps to manage cough, where Ammonium chloride is an expectorant that works by decreasing the stickiness of airway secretions and helps in their removal from the airways. Diphenhydramine is an antihistaminic that relieves allergy symptoms like watery eyes, sneezing, and a runny nose. Menthol is a demulcent and soothing agent that helps to give the sensation of breathing easier and reduces cough by acting on the cold receptors present in the nose and throat. Sodium Citrate belongs to Mucolytic, thins and loosens phlegm in the nose, trachea and lungs helps to make coughing easier.
How to use COFFDRYL SYRUP
Take COFFDRYL SYRUP as advised by your physician. Shake well before use. Your physician will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Side Effects Of COFFDRYL SYRUP
Common
- dry mouth
- dizziness
- headache
- nausea, vomiting
- gastrointestinal discomfort
Rare
- low blood pressure
- muscle spasms
- confusion
- depression
- disturbed sleep
- tremors
- convulsions
- irregular heartbeat or palpitations
- allergic reactions
- blood disorders
Stop taking COFFDRYL SYRUP and contact your physician immediately if you experience any of the following side effects:
- spontaneous bruising or bleeding (may be signs of a blood disorder)
How To Manage Side Effects

Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid operating any machines or driving while you are feeling dizzy. Do not consume alcohol, as it increases dizziness. Contact your doctor if dizziness or drowsiness did not improve.

Nausea And Vomiting
Take this medicine with, or just after food. Eat simple meals and avoid oily or spicy foods. Contact your doctor if the nausea or vomiting did not improve.
Warning & Precautions

Pregnancy
Monitoring requiredCOFFDRYL SYRUP is not recommended for use in pregnancy unless considered clearly necessary. Contact your doctor before taking.

Breastfeeding
Use with CautionCOFFDRYL SYRUP should be used with caution in breastfeeding women as it is not known whether it may pass through breast milk. Contact your doctor before taking.

Driving and Using Machines
Use with CautionDo not drive or operate machines if you feel drowsiness after taking COFFDRYL SYRUP.

Alcohol
ContraindicatedAvoid alcohol consumption while taking COFFDRYL SYRUP as it may lead to unwanted effects.

Liver
Use with CautionCOFFDRYL SYRUP should be used with caution in patients with liver dysfunction. Contact your doctor before taking.

Allergy
ContraindicatedDo not use COFFDRYL SYRUP if you are allergic to Ammonium Chloride, Diphenhydramine, Menthol, Sodium Citrate, or any other ingredients of the medicine.

Lungs
Use with CautionCOFFDRYL SYRUP should be used with caution in patients with lung diseases. Contact your doctor before taking.

Heart Disease
Use with CautionCOFFDRYL SYRUP should be used with caution in patients with heart rhythm problems. Contact your doctor before taking.

Use In Pediatrics
Consult your doctorCOFFDRYL SYRUP is not recommended to use in new born and premature infants and in children below 6 years of age and it should be used with caution in children above 6 years of age. Contact your doctor before taking.

Use In Geriatrics
Use with CautionCOFFDRYL SYRUP should be used with caution in elderly patients aged 65 years or above. Contact your doctor before taking.
Others
COFFDRYL SYRUP is not recommended for use if you have:
- porphyria
- persistent chronic cough (cough occurs with smoking, asthma, emphysema, or when the cough is accompanied by excessive secretions)
- epilepsy
- glaucoma
- difficult urination
Before taking COFFDRYL SYRUP, inform your doctor if you have:
- stenosing peptic ulcer
- pyloroduodenal obstruction
- symptomatic prostatic hypertrophy or bladder-neck obstruction
- hyperthyroidism
Interactions
A. Drug-Drug interactions:
Before taking COFFDRYL SYRUP, inform your physician if you are taking any of the following medicine:
- monoamine oxidase (MAO) inhibitors Ex. estazolam, zolpidem (medicines used as sedatives and hypnotics)
- diazepam, alprazolam (medicines used as tranquilizers)
- ephedrine (medicine used to manage nasal congestion, diabetic swelling, and other conditions)
Overdosage:
If you or anyone else accidentally takes too much of COFFDRYL SYRUP, consult your doctor immediately or visit the nearby hospital.
Synopsis
Drug | : | Ammonium Chloride, Diphenhydramine, Menthol, Sodium Citrate |
Pharmacological Category | : | Expectorant, Antihistaminic, Demulcent or Soothing agent, Mucolytics |
Therapeutic Indication | : | Cough |
Dosage Forms | : | Syrup, Expectorant, Liquid |
More Information
- Keep COFFDRYL SYRUP out of the sight and reach of children
- Store COFFDRYL SYRUP below 25°C
FAQs About COFFDRYL SYRUP
Q: For what conditions COFFDRYL SYRUP is used?
A: COFFDRYL SYRUP used to relieve allergy symptoms such as colds, hay fever, sneezing, coughing, itching, watery red eyes, and runny or blocked nose.
Q: Can I use COFFDRYL SYRUP in children?
A: COFFDRYL SYRUP is not recommended to use in new born and premature infants and in children below 6 years of age and it should be used with caution in children above 6 years of age. Contact your doctor before taking.
Q: Does COFFDRYL SYRUP cause dizziness?
A: Yes. COFFDRYL SYRUP may cause dizziness. Avoid operating any machines or driving while you are feeling dizzy. Do not consume alcohol, as it increases dizziness. Contact your doctor if the dizziness did not improve.
Q: Is it safe to use COFFDRYL SYRUP in pregnant and breastfeeding women?
A; COFFDRYL SYRUP is not recommended for use among women who are pregnant and breastfeeding unless considered clearly necessary. Contact your doctor before taking.
Q: When to seek medical emergency?
A: Stop taking COFFDRYL SYRUP and contact your physician immediately if you experience spontaneous bruising or bleeding (which may be signs of a blood disorder) and accidentally take too much of COFFDRYL SYRUP.
References
1. K.D. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 218, 220, 221.
2. Peter V. Dicpinigaitis, Sean Dhar, Amber Johnson, Yvonne Gayle, John Brew, and Wilson Caparros-Wanderley. Inhibition of cough reflex sensitivity by diphenhydramine during acute viral respiratory tract infection. International Journal of Clinical Pharmacy. February 2015. [Accessed on 22nd August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409637/
3. Wellona Pharma. Family cough medicines. [Accessed on 22nd August 2022] https://wellonapharma.com/product/finished/diphenhydramine-ammonium-chloride-sodium-citrate-and-menthol-syrup
4. DM Pharma. Darcet Syrup. [Accessed on 22nd August 2022] http://dmpharma.co.in/DARCET%20Syrup.html
5. MIMS. Sunex syrup. [Accessed on 22nd August 2022] https://www.mims.com/malaysia/drug/info/sunex?type=full
6. Dailymed.com. Silphen syrup. [Revised in August 2020] [Accessed on 22nd August 2022] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d18e22f2-8cda-4862-b437-e83648a5108a
7. Laleham Health and Beauty Limited. Unicough Oral Solution. [Revised in September 2015] [Accessed on 22nd August 2022] https://www.boots.com/wcsstore/ExtendedSitesCatalogAssetStore/Product_PatientLeaflets/A00000545-10210894.P-10210894_-_Unicough_-_PIL.pdf