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COF Q Lozenges 6'S

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Introduction About COF Q LOZENGES

COF Q LOZENGES contains a combination of Amylmetacresol and Dextromethorphan which belongs to the group of medicines called Antiseptic and Antitussives respectively. It is used for the relief of acute nonproductive cough associated with sore throat.

COF Q LOZENGES should be used with caution in patients with lung problems such as asthma, emphysema and chronic bronchitis, liver problems. Consult your doctor before taking it.

COF Q LOZENGES should be used with caution in pregnant women. The safety and effectiveness of COF Q LOZENGES in breastfeeding women has not been established yet. Consult your doctor before taking it.

COF Q LOZENGES is not recommended for use in children below 12 years of age. It should be used with caution in elderly patients. The side effects of taking COF Q LOZENGES is sore tongue. Consult your doctor if any of the side effect worsens.

Uses Of COF Q LOZENGES

Manage:

  • acute nonproductive cough associated with sore throat

How COF Q LOZENGES Works

COF Q LOZENGES works by relieving the cough and sore throat where Amylmetacresol is an antiseptic works by killing the bacteria associated with mouth and throat infections. Dextromethorphan is a Cough suppressant which relieves cough by acting on the cough center in the brain.

How to use COF Q LOZENGES

Take COF Q LOZENGES as advised by your physician. Place it in your mouth and allow it to dissolve slowly. Do not chew or swallow the medicine.

Side Effects Of COF Q LOZENGES

Uncommon

  • sore tongue

Rare

Stop taking COF Q LOZENGES and contact your doctor immediately if you experience any of the following side effects:

  • difficulty in breathing, swelling of the face, neck, tongue or throat and rash (severe allergic reactions)

Warning & Precautions

Pregnancy

Use with Caution

COF Q LOZENGES should be used with caution in pregnant women. Consult your doctor before taking it.

Breastfeeding

Consult your doctor

The safety and effectiveness of COF Q LOZENGES in breastfeeding women has not been established yet. Consult your doctor before taking it.

Liver

Use with Caution

COF Q LOZENGES should be used with caution in patients with liver problems. Consult your doctor before taking it.

Allergy

Contraindicated

Do not take COF Q LOZENGES if you are allergic to Amylmetacresol or Dextromethorphan or any other ingredients of this medicine.

Lungs

Use with Caution

COF Q LOZENGES should be used with caution in patients with lung problems such as asthma, emphysema (a lung disease that causes shortness of breath) or chronic bronchitis (productive cough). Consult your doctor before taking it.

Others

Before taking COF Q LOZENGES, inform your doctor if you:

  • have diabetes
  • have intolerance to sugars

Use in Pediatrics:

COF Q LOZENGES is not recommended for use in children below 12 years of age. Consult your doctor before taking it.

Use in Geriatrics:

COF Q LOZENGES should be used with caution in elderly patients. Consult your doctor before taking it.

Interactions

A. Drug - Drug interactions:

Before taking COF Q LOZENGES, inform your doctor if you are taking any of the following medicine:

  • monoamine oxidase inhibitors (medicines used to manage depression) (Ex. selegiline, phenelzine, isocarboxazid)

Overdosage:

If you or anyone else accidentally take too much of COF Q LOZENGES, consult your doctor immediately or visit the nearby hospital.

Synopsis

Drug :   Amylmetacresol, Dextromethorphan
Pharmacological Category :   Antiseptic, Antitussives
Therapeutic Indication :   Acute nonproductive cough associated with sore throat
Dosage Forms :   Lozenges

More Information

  • Keep COF Q LOZENGES out of reach of children
  • Store below 30°C

FAQs About COF Q LOZENGES

Q: How often can I take COF Q LOZENGES?

A: COF Q LOZENGES should be used for the relief of acute nonproductive cough associated with pain in adults, the elderly and children 12 years of age and above. Dissolve two lozenges in the mouth, one after the other, every 4 hours as needed and do not exceed the recommended daily dose. Contact your doctor if symptoms persist.

Q: How to take COF Q LOZENGES?

A: Take COF Q LOZENGES as advised by your physician. Place it in your mouth and allow it to dissolve slowly. Do not chew or swallow the medicine.

Q: Is COF Q LOZENGES safe to use?

A: Yes. COF Q LOZENGES is safe to use in adults, the elderly and children aged 12 years and above. This medicine may cause sore tongue and it should be used with caution in patients with asthma, emphysema, chronic bronchitis and liver disease. Consult your doctor for advice.

Q: How COF Q LOZENGES relives sore throat?

A: COF Q LOZENGES works by relieving the cough and sore throat where Amylmetacresol is an antiseptic works by killing the bacteria associated with mouth and throat infections. Dextromethorphan is a Cough suppressant which relieves cough by acting on the cough center in the brain.

Q: Can COF Q LOZENGES be used in children?

A: COF Q LOZENGES is not recommended for use in children below 12 years of age. It should be used with caution in children aged 12 years and above. Consult your doctor for advice before taking this medicine.

Q: Can COF Q LOZENGES be used in pregnancy?

A: COF Q LOZENGES should be used with caution in pregnant women. Inform your doctor if you are pregnant or planning for pregnancy before taking it. If you become pregnant while taking COF Q LOZENGES, contact your doctor.

References

1. KD Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Eighth Edition. 2019. Page –239.

2. Derek Matthews, Robert Atkinson and Adrian Shephard. Spectrum of bactericidal action of amylmetacresol/2,4-dichlorobenzyl alcohol lozenges against oropharyngeal organisms implicated in pharyngitis. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. November 2018. [Accessed on 2nd August 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276617/

3. Bridgette Martinak, Ramy A. Bolis, Jeffrey Ryne Black, Rachel E. Fargason and Badari Birur. Dextromethorphan in Cough Syrup: The Poor Man’s Psychosis. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. September 2017. [Accessed on 2nd August 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601090/

4. Bethesda (MD). Dextromethorphan. NIH National Library of Medicine, National Center for Biotechnology Information. PubChem Compound Summary. 2004. [Accessed on 2nd August 2022]. https://pubchem.ncbi.nlm.nih.gov/compound/Dextromethorphan

5. The Boots Company. Electronic Medicines Compendium (EMC). [Revised in November 2016] [Accessed on 2nd August 2022]. https://www.medicines.org.uk/emc/files/pil.9078.pdf

6. TusQ-D Cough lozenges (Amylmetacresol + Dextromethorphan). Blue cross laboratories Ltd. [Accessed on 2nd August 2022].  https://bluecrosslabs.com/product/dry-cough-tusq-d-cough-lozenges-available-in-orange-honey-lemon/#4

7. Strepsils Dry Cough Lozenges (Dextromethorphan). Reckitt Benckiser. [Accessed on 2nd August 2022]. https://www.strepsils.com.ph/products/sore-throat-with-cough/dry-cough/, https://www.strepsils.com.ph/faqs/#faq-8

8. Throsils - D+ (Amylmetacresol + Dextromethorphan). Cibanova. [Accessed on 2nd August 2022]. https://www.cibanova.com/cough_lozenges.html

9. MIMS. Amylmetacresol. [Accessed on 2nd August 2022]. https://www.mims.com/malaysia/drug/info/amylmetacresol?mtype=generic

10. Bethesda (MD). Dextromethorphan. National Institute of Health: National Library of Medicine. Medline Plus. January 2022. [Accessed on 2nd August 2022]. https://medlineplus.gov/druginfo/meds/a682492.html

Author Details

Written By Dr. N. Sai Swaroop - Pharm.D
Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)
Last updated on 04 Feb 2023 | 01:53 PM(IST)
Lab updated