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Zydus Healthcare Limited

Codeine Sulphate Tablet 10'S

Pain relief
MRP ₹64.00 (Inclusive of all taxes)
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    Introduction About CODEINE SULPHATE TABLET

    CODEINE SULPHATE TABLET contains Codeine which belongs to the group of medicines called Opioids. It is used to provide relief from cough and pain. It can also be used to manage the symptoms of persistent diarrhea.

    Before taking CODEINE SULPHATE TABLET inform your doctor if you have any previous history of drug abuse, addiction or developed withdrawal symptoms after stopping an opioid medication.

    You must also inform your doctor if you have any liver problems, kidney problems, low blood pressure, breathing difficulties (Ex. asthma), bowel inflammation, fits, any mental illnesses, muscle problems, thyroid problems, or any surgery in the gut or urinary tract as a precaution.

    Take CODEINE SULPHATE TABLET only for the duration recommended by your doctor. Do not overuse or misuse this medicine as it may make you feel getting addicted to it. While undergoing therapy with CODEINE SULPHATE TABLET, inform your doctor if you suddenly couldn’t notice any improvement in your condition. This is because, your body might have become tolerant to this medicine, and you may need a higher dose to see the desired result.

    Do not take CODEINE SULPHATE TABLET without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of taking CODEINE SULPHATE TABLET are dizziness, drowsiness, tiredness, mood changes, nightmares, restlessness, constipation, dry mouth, constricted pupils, fast heart rate and decrease in sex drive. Consult your doctor if any of these side effect troubles you.

    Uses Of CODEINE SULPHATE TABLET

    • Relieves cough
    • Manage moderate pain that is not relieved by other pain killers
    • Manages the symptoms of persistent diarrhea

    How CODEINE SULPHATE TABLET Works

    CODEINE SULPHATE TABLET is an opioid medication. It works by changing the way your brain responds to pain. It interrupts the transmission of pain signals between the affected regions and the brain. It reduces cough by suppressing the activity of certain parts of the brain that triggers cough reflexes.

    How to use CODEINE SULPHATE TABLET

    Take CODEINE SULPHATE TABLET as advised by your physician. It can be taken with or without meals. Swallow the medicine with a glass of water. Do not crush or chew the medicine.

    Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and health condition. Do not take this medicine for more than 3 days continuously without consulting your doctor.

    Side Effects Of CODEINE SULPHATE TABLET

    Common

    • dizziness, drowsiness, tiredness
    • confusion
    • mood changes, nightmares, depression, restlessness
    • headache
    • hallucinations (seeing, feeling or hearing things that are not real)
    • nausea, vomiting, constipation, dry mouth, stomach pain
    • low body temperature
    • blurred or double vision, constricted pupils
    • fast heart rate, low blood pressure
    • malaise (general discomfort)
    • pain or difficulty in passing urine
    • abnormal muscle movements and rigidity
    • decrease in sex drive

    Stop taking CODEINE SULPHATE TABLET and contact your doctor immediately if you experience any of the following side effects such as:

    • signs of allergic reaction (such as skin rash, itching, redness, sweating, flushed face, swelling of the face, lips, tongue, and/or throat which can lead to difficulty in breathing)
    • increased pressure in the head
    • fits
    • exacerbation of previous pain
    • slow or shallow breathing, confusion, sleepiness, nausea, vomiting, small pupils, constipation and lack of appetite

    How To Manage Side Effects

    Diarrhea

    Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens, contact your doctor.

    Dizziness Or Drowsiness

    Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy or drowsy. Do not consume excessive alcohol, as it could aggravate your sleepiness. Consult your doctor if your condition worsens.

    Dry Mouth

    Drink plenty of water and fruit juices. Consume foods which has high water and fiber content. Artificial saliva can also be used in extreme dryness of mouth. If your condition worsens, contact your doctor.

    Headache

    Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

    Warning & Precautions

    Pregnancy

    Risky

    CODEINE SULPHATE TABLET should not be used in pregnant women unless considered necessary by the physician. Your doctor will prescribe this medicine after evaluating the benefits of the therapy to the mother and the potential risks to the foetus. Therefore, consult your doctor before taking it.

    Breastfeeding

    Contraindicated

    CODEINE SULPHATE TABLET may pass through breast milk. Therefore, it should not be used in breastfeeding women. Consult your doctor for advice.

    Driving and Using Machines

    Contraindicated

    CODEINE SULPHATE TABLET may cause drowsiness, hallucination, blurred vision, confusion, fits or dizziness. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by CODEINE SULPHATE TABLET.

    Alcohol

    Consult your doctor

    Avoid consumption of alcohol while taking CODEINE SULPHATE TABLET as it might make you feel sleepy.

    Kidney

    Use with Caution

    CODEINE SULPHATE TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.

    Liver

    Consult your doctor

    CODEINE SULPHATE TABLET is not recommended for use in patients with liver failure. It should be used with caution in patients with other liver problems, gall stones or gall bladder problems. Therefore, consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take CODEINE SULPHATE TABLET if you are allergic to Codeine.

    Lungs

    Contraindicated

    CODEINE SULPHATE TABLET is not recommended for use in patients with chronic lung disease, breathing problems or an active asthma attack. Therefore, consult your doctor before taking it.

    Heart Disease

    Use with Caution

    CODEINE SULPHATE TABLET should be used with caution in patients with an irregular heartbeat or low blood pressure. Therefore, consult your doctor before taking it.

    Use In Pediatrics

    Consult your doctor

    CODEINE SULPHATE TABLET can be used in children and adolescents (aged 12 years or above) if prescribed by the physician. It is not recommended for use in children aged below 12 years. It is also not suitable for use in children with compromised respiratory function and in children who have undergone removal of tonsils or adenoids. Therefore, consult your doctor for advice.

    Use In Geriatrics

    Use with Caution

    CODEINE SULPHATE TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.

    Others

    CODEINE SULPHATE TABLET is not recommended for use if you:

    • suffered a head injury or raised pressure in the skull (symptoms include painful eyes, vision changes, headache behind the eyes)
    • drink a lot of alcohol (alcoholism)
    • suffer from diarrhea associated with severe bowel inflammation
    • are at risk of having a blockage in your intestines

    Before taking CODEINE SULPHATE TABLET, inform your doctor if you:

    • have a history of drug abuse (opioids, alcohol, etc.)
    • previously suffered withdrawal symptoms (such as anxiety, agitation, shaking or sweating) after stopping the use of opioid medicines
    • have any mental illnesses
    • have fits
    • have recently undergone any surgery in your gut or in urinary system
    • are in shock (sudden loss of blood circulation)
    • have thyroid dysfunction
    • have an enlarged prostate
    • have any acute stomach conditions or inflammations that can cause bloody diarrhea
    • suffer from severe muscle weakness
    • have problems with your adrenal glands (such as Addison’s disease)
    • have phaeochromocytoma (tumour on top of adrenal glands)

    Interactions

    A. Drug-Drug interactions

    Before taking CODEINE SULPHATE TABLET, inform your doctor if you are taking any of the following medicines:

    • medicines used to manage depression such as mono-amine oxidase inhibitors (Ex. phenelzine, moclobemide, selegiline or isocarboxazid) or tricyclic antidepressants (such as amitriptyline, nortriptyline)
    • phenobarbitone (a medicine used to control of fits)
    • medicines used to reduce anxiety and to induce sleep (such as alprazolam, midazolam, clonazepam, lorazepam, nitrazepam, diazepam, temazepam)
    • medicines used for diarrhoea (Ex. loperamide, kaolin)
    • medicines used to manage hypertension (such as atenolol, propranolol, amlodipine, telmisartan, olmesartan etc.)
    • cimetidine (a medicine used to manage stomach ulcers)
    • ciprofloxacin (a medicine used to manage bacterial infection)
    • metoclopramide or domperidone (used to manage nausea and vomiting)
    • mexiletine or quinidine (used to manage irregular heartbeats)
    • medicines used to manage HIV infection (such as ritonavir)
    • medicines to manage allergic conditions (such as cetirizine, levocetirizine)
    • atropine (a medicine used to restore heart rate and control body secretions and muscle movements)
    • chlorpromazine (used to manage mental illnesses)
    • anaesthetics (used to cause numbness or loss of consciousness) such as lidocaine, sevoflurane, halothane
    • opioid antagonists (such as buprenorphine, naltrexone, naloxone) used to reverse the effects of opioids

    B. Drug - Food interactions:

    CODEINE SULPHATE TABLET can be taken with or without meals.

    Overdosage:

    If you or anyone else accidentally took more CODEINE SULPHATE TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose may include nausea, vomiting, depression, low blood pressure, constricted pupils, fast heart rate and slow breathing.

    Synopsis

    Drug :   Codeine
    Pharmacological Category :   Natural Opium Alkaloids
    Therapeutic Indication :   Cough suppressants   
    Dosage Forms :   Tablet, Syrup, Linctus

    More Information

    • Keep CODEINE SULPHATE TABLET out of reach of children
    • Store CODEINE SULPHATE TABLET at room temperature

    FAQs About CODEINE SULPHATE TABLET

    Q: What is the use of CODEINE SULPHATE TABLET?

    A: CODEINE SULPHATE TABLET is used to provide relief from cough and pain. It can also be used to manage the symptoms of persistent diarrhea.

    Q: Is CODEINE SULPHATE TABLET addictive in nature?

    A: Yes. CODEINE SULPHATE TABLET is addictive in nature. Therefore, take this medicine only for the duration recommended by your doctor. Do not overuse or misuse this medicine as it may make you feel getting addicted to it.

    Q: What are the withdrawal symptoms caused by the prolong usage of CODEINE SULPHATE TABLET?

    A: Stopping the use of CODEINE SULPHATE TABLET after a prolong period can cause withdrawal symptoms such as restlessness, problems in falling asleep, irritability, agitation, anxiety, palpitations, high blood pressure, nausea, vomiting, diarrhoea, shaking, shivering or sweating.

    Q: Can CODEINE SULPHATE TABLET be used in children?

    A: CODEINE SULPHATE TABLET can be used in children and adolescents (aged 12 years or above) if prescribed by the physician. It is not recommended for use in children aged below 12 years. It is also not suitable for use in children with compromised respiratory function and in children who have undergone removal of tonsils or adenoids. Therefore, consult your doctor for advice.

    Q: Can CODEINE SULPHATE TABLET cause headaches? 

    A: Yes. Headache is one of the most common side effects of taking CODEINE SULPHATE TABLET. In case of you are experiencing a headache after taking CODEINE SULPHATE TABLET, try to rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol. Consult your doctor if headache persists for a long time.

    Q: Who can use CODEINE SULPHATE TABLET?

    A: CODEINE SULPHATE TABLET is suitable for use in both adults and in children (aged 12 years or above).

    Q: How CODEINE SULPHATE TABLET works?

    A: CODEINE SULPHATE TABLET is an opioid medication. It works by changing the way your brain responds to pain. It interrupts the transmission of pain signals between the affected regions and the brain. It reduces cough by suppressing the activity of certain parts of the brain that triggers cough reflexes. 

    Q: What is the best time to take CODEINE SULPHATE TABLET?

    A: CODEINE SULPHATE TABLET can be taken with or without meals. Your doctor will decide the correct dose, time of administration and duration of therapy for you depending upon your age, body weight and health condition

    Q: What to do if I forgot to take a dose of CODEINE SULPHATE TABLET?

    A: If you have missed a dose of CODEINE SULPHATE TABLET, take it as soon as you remember. However, if it is time for the next dose of CODEINE SULPHATE TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of CODEINE SULPHATE TABLET to compensate the missed ones.

    Q: Can I consume alcohol while taking CODEINE SULPHATE TABLET?

    A: Avoid consumption of alcohol while taking CODEINE SULPHATE TABLET as it might make you feel sleepy.

    Q: Can I drive after taking CODEINE SULPHATE TABLET?

    A: CODEINE SULPHATE TABLET may cause drowsiness, hallucination, blurred vision, confusion, fits or dizziness. Therefore, do not drive or operate any heavy tools or machines if your ability is affected by CODEINE SULPHATE TABLET.

    Q: Can the use of CODEINE SULPHATE TABLET affect the liver?

    A: Yes. CODEINE SULPHATE TABLET may affect the way your liver work. Therefore, it should be used with caution in patients with liver problems. Consult your doctor before taking it.

    Q: Can CODEINE SULPHATE TABLET be taken during pregnancy?

    A: CODEINE SULPHATE TABLET should not be used in pregnant women unless considered necessary by the physician. Your doctor will prescribe this medicine after evaluating the benefits of the therapy to the mother and the potential risks to the foetus. Therefore, consult your doctor before taking it.

    Q: Can CODEINE SULPHATE TABLET make my child feel sleepy?

    A: CODEINE SULPHATE TABLET may cause sleepiness or drowsiness in few children, although not everybody gets them. This is quite normal and does not need to worry about. Avoid unnecessary distractions in children and try to make them stay relaxed. Avoid taking them outdoors unnecessarily. Avoid giving them concomitant medicines that can make them drowsier like cough syrups or sedatives. If this symptom bothers you, contact your doctor for advice.

    References

    1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Opioid Analgesics and Antagonists. Essentials of Medical Pharmacology. seventh edition. 2013. Page – 220 & 474.

    2. Basil V. Peechakara; Jack G. Tharp; Mohit Gupta. Codeine. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. February 2023. [Accessed on 28th March 2023] https://www.ncbi.nlm.nih.gov/books/NBK526029/#:~:text=Codeine%20is%20the%20most%20commonly,are%20pain%20and%20dry%20cough.&text=Codeine%20plays%20a%20role%20in%20the%20treatment%20of%20mild%20to%20moderate%20pain.

    3. Sun Pharmaceutical Industries Europe B.V. Codeine Phosphate Tablet 15 and 30mg. Electronic Medicines Compendium (EMC). [Revised in June 2021]. [Accessed on 28th March 2023] https://www.medicines.org.uk/emc/files/pil.2616.pdf

    4. Codeine. MedlinePlus. NIH. National Library of Medicine. American Society of Health-System Pharmacists. December 2020. [Accessed on 28th March 2023] https://medlineplus.gov/druginfo/meds/a682065.html

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 31 Mar 2023 | 10:37 AM(IST)
    Lab updated