Choltran Sachet 5gm

Introduction About CHOLTRAN SACHET

Choltran Sachet is a bile acid-binding resin powder supplied for oral suspension. It is used under medical guidance as part of clinician-directed care plans. The sachet is designed for measured, single-serve mixing to support consistent use. It should be used only on clinician advice. Do not swallow the dry powder.

Empty the full Choltran Sachet into a glass (about 120-180 mL) of water or other non-carbonated liquid. Stir until the powder is evenly dispersed, slight settling may occur. Drink the entire mixture. Rinse the glass with a small amount of liquid and drink to ensure the full dose is consumed. Follow the dosing schedule and timing with other medicines as advised by your clinician.

Before taking Choltran Sachet, inform your doctor about your current medicines, supplements, and any digestive or liver concerns with your clinician before use. This product can influence the absorption of other oral medicines; a gap is commonly advised.

Discuss use in pregnancy or breastfeeding with your clinician. If you notice constipation, abdominal discomfort, or changes in stool pattern. Consult your doctor for advice.

Key Composition

• Cholestyramine

Uses Of CHOLTRAN SACHET

• Supports cholesterol management plans   
• Helps in bile acid related digestive concerns  
• Used as an adjunct in lipid-lowering strategies
• For specific liver and gallbladder related care needs
• Suitable for patients unable to swallow tablets

Benefits of CHOLTRAN SACHET

1. Convenient powder form – Easy to mix with water, juice, or soft foods, making it suitable for individuals who prefer alternatives to tablets or capsules.

2. Local action in the gut – Works without entering the bloodstream, reducing the risk of systemic side effects.

3. Can be part of a personalized cholesterol care plan – Often advised alongside diet and exercise for patients requiring a bile acid sequestrant.

4. May support digestive comfort in bile acid–related concerns – Binds bile acids in the intestine, aiding their removal.

5. Flexible dosing – Can be taken before or after meals, as recommended by a healthcare provider, allowing it to fit into varied lifestyles.

How CHOLTRAN SACHET Works

1. How Choltran Sachet 5 gm Works in the Body:

Choltran Sachet 5 gm contains Cholestyramine resin, a bile acid sequestrant that acts locally in the digestive tract. After mixing with a liquid or soft food, it binds to bile acids in the intestine. This binding prevents bile acids from being reabsorbed and helps remove them from the body through natural bowel movements. By altering bile acid circulation, it can support cholesterol-lowering strategies and help manage bile acid–related digestive concerns.

2. The Role of Cholestyramine Resin in Choltran Sachet:

Cholestyramine resin is a non-absorbable polymer that stays in the gastrointestinal tract. Its primary role is to trap bile acids, which are made from cholesterol, and carry them out of the body. This process encourages the liver to use more cholesterol to make new bile acids, which can help lower cholesterol levels over time when used alongside diet and lifestyle changes. The resin’s action is purely local, meaning it is not absorbed into the bloodstream which is a feature that contributes to its targeted effect and safety profile for many patients.

How to use CHOLTRAN SACHET

1. Step-by-Step Mixing Instructions:

• Empty the full contents of Choltran Sachet 5 gm into a glass.
• Add 60–180 ml (about half to three-quarters of a cup) of water, fruit juice, or other approved liquid.
• Stir well until the powder is fully dispersed — it may not dissolve completely, but should form an even suspension.
• Drink the mixture immediately after preparing it.
• Rinse the glass with a small amount of liquid, swirl, and drink to ensure you consume the full dose.

2. Tips for Easy Mixing and Better Tolerance:

• Use cool or room temperature liquids for better dispersion.
• You can mix with soft foods such as applesauce, soup, or yogurt if preferred.
• Sip slowly to avoid gulping air, which can cause bloating.
• Maintain adequate hydration throughout the day to support digestive comfort.
• Space other medicines at least 1 hour before or 4–6 hours after taking Choltran Sachet to avoid interaction.

What if I forgot to take CHOLTRAN SACHET

• Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose.
• If it is close to the next dose, skip the missed one — never double up to make up for it.
• Resume your regular dosing schedule and consult your healthcare provider if you frequently forget doses.

Overdose

If you or anyone else accidentally takes too much of Choltran Sachet 5 gm consult your doctor immediately or visit the nearby hospital.

Side Effects Of CHOLTRAN SACHET

Choltran Sachet might cause constipation in some individuals. Consult your doctor if you notice any such side effects while taking it.

How To Manage Side Effects

Constipation

• Increase daily fluid intake — Aim for at least 8–10 glasses of water unless advised otherwise.
• Add fiber-rich foods such as whole grains, fresh fruits, and vegetables to your meals.
• Stay physically active with gentle walking, stretching, or other light exercises to support bowel regularity.
• If constipation persists, speak to your healthcare provider about adjusting the dosage or timing.
• Avoid taking fibre supplements or laxatives without professional guidance, as they may affect how the medicine works.

Warning & Precautions

Pregnancy

Consult your doctor

Consult the doctor if you are pregnant women before using Choltran Sachet.

Breastfeeding

Consult your doctor

Consult the doctor if you are breastfeeding women before using Choltran Sachet.

Alcohol

Consult your doctor

Keep your alcohol intake within the recommended limits as advised by your doctor, as alcohol can increase your cholesterol level

Kidney

Use with Caution

Choltran Sachet should be used with caution if you have kidney problems.

Liver

Use with Caution

Choltran Sachet should be used with caution if you have liver problems.

Allergy

Contraindicated

Do not take Choltran Sachet if you are allergic to any of its components.

Use In Pediatrics

Contraindicated

Choltran Sachet should not be used for children below 6 years of age.

Use In Geriatrics

Use with Caution

Elderly patients using Choltran Sachet 5 gm may require additional considerations to ensure safe and effective use. As ageing can affect digestion, nutrient absorption, and hydration levels, close monitoring is important.

Who should not take [GBNKEYWORD

Choltran Sachet is not recommended for individuals with a history of:

• chronic constipation
• bowel obstruction
• severe gastrointestinal conditions

Safety Advice

• Always take Choltran Sachet as advised by your physician
• Mix the powder with milk, thin soups, fruit smoothies, sauces (Ex. apple sauce) or water, stir well and consume the mixture immediately
• Do not mix with too much hot or cold water
• Do not take it in its dry form as it may cause you to choke
• Do not take Choltran Sachet if you are allergic to any of its components
• Keep your alcohol intake within the recommended limits as advised by your doctor, as alcohol can increase your cholesterol level
• Ask your doctor before taking it during pregnancy or breast-feeding
• Choltran Sachet should not be used for children below 6 years of age
• Inform your doctor if you have bile duct being completely blocked, or a family history of high cholesterol levels
• Inform your doctor on all the medicines you use, including prescription, over-the-counter medications and herbal supplements

Mixing Guide: Liquids That Work Well with Choltran Sachet 5 gm

Diet and Lifestyle Advice

• Stay Hydrated: Aim for 6–8 glasses of water daily to help maintain smooth digestion and reduce the risk of constipation often associated with cholestyramine
• Add Fibre Gradually: Include fibre-rich foods like whole grains, fruits, and vegetables. Increasing fibre slowly can help your digestive system adjust comfortably
• Space out Other Medicines: To avoid potential interactions, take other medicines at least 1 hour before or 4–6 hours after your Choltran dose
• Limit High-Fat Meals: Opt for lean proteins, steamed or grilled foods, and healthy fats such as those from nuts, seeds, and olive oil
• Stay Active: Light exercises such as walking, yoga, or stretching can promote healthy digestion and circulation
• Mind Vitamin Intake: Ask your healthcare provider about monitoring fat-soluble vitamins (A, D, E, K) and whether supplements may be helpful

How it fits into a low-fat diet plan or post-meal routine

• For individuals advised to follow a low-fat eating plan, Choltran Sachet 5 gm can be seamlessly incorporated into daily habits. Taking it after a meal rich in healthy, low-fat options—such as steamed vegetables, grilled lean protein, and whole grains—can help align your dosage with your nutrition goals.
• Since the sachet contains cholestyramine resin, it works best when taken at a consistent time each day, often linked to post-meal routines for convenience. This approach not only supports adherence to your healthcare provider’s plan but also ensures you space it appropriately from other medicines for optimal benefit.
• Pairing Choltran with a low-fat diet rich in fresh produce, fibre, and hydration can help you maintain digestive comfort and nutrient balance. Using the sachet as part of a mealtime habit—such as preparing it right after lunch or dinner—can make it easier to remember and more convenient to fit into your day.

Drug - Drug interaction

Thyroid hormones - Absorption may be reduced; a timing gap may be advised

Fat-soluble vitamins (A, D, E, K) - Long-term use may affect vitamin uptake; discuss supplementation and timing

Other oral medicines - General practice is to separate by a gap as directed by your clinician

• warfarin
• chlorothiazide (acidic)
• phenylbutazone
• phenobarbital
• tetracycline
• penicillin G
• digitalis

Synopsis

More Information

5 Easy Ways to Mix Choltran without Clumps

Getting a smooth mix with Choltran Sachet 5 gm can make it easier to take and more pleasant to drink. Here are five simple methods patients often find helpful:

1. Start with Lukewarm Water – Use about 100–150 ml of lukewarm water, which helps the powder disperse faster.
2. Add Powder Slowly – Sprinkle the sachet contents gradually into the liquid while stirring to prevent lumps from forming.
3. Use a Shaker Bottle – A shaker with a mixing ball can break up clumps effectively and give you a smoother texture.
4. Mix with Non-Carbonated Juice – Low-acid juices like apple or grape can improve taste and texture while keeping the mix lump-free.
5. Stir, Let Sit, Then Stir Again – Allowing the mixture to stand for 1–2 minutes lets the powder absorb liquid evenly before a final stir.

Pharmacist’s Tip: Reducing Clumping During Mixing

When preparing Choltran Sachet 5 gm, adding the powder to a small amount of lukewarm water or non-carbonated beverage first and stirring gently can help reduce clumping. Once fully dispersed, you can top up with more liquid if desired. Avoid adding the entire sachet directly to a full glass at once, as this may cause uneven mixing. Using a shaker bottle or a spoon with a wide bowl can also make the process smoother and more comfortable to drink.

Travel-Ready Sachets & Portability Advantage

The single-use Choltran Sachet 5 gm format makes it easy to carry and use on the go. Whether travelling for work or leisure, these pre-measured sachets fit easily into a handbag or travel pouch, allowing you to maintain your prescribed schedule without hassle. Since no refrigeration is required, they are particularly convenient for long journeys or locations with limited storage facilities.

FAQs About CHOLTRAN SACHET

References

1. Neon Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised on Feb 2024] [Accessed on 12th August 2025]

2. Pharmascience Inc. [Revised on 8th April 2024] [Accessed on 12th August 2025]

3. Sterisindia. [Accessed on 12th August 2025]

Author Details

Written By Dr. Karthikeyan Rajagopal - M.Pharm (Pharmacology)

Reviewed For Accuracy By Dr. Venkatesh Poludasu - MBBS

Last updated on 14 Aug 2025 | 03:28 PM(IST)