CEKOZEF S 1.5 Injection 20ml
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Introduction About CEKOZEF S 1.5 INJECTION
CEKOZEF S 1.5 INJECTION contains Cefoperazone which belongs to the group of medicines called Antibiotics. It is used to manage bacterial infections of the respiratory tract, urinary tract, genital tract, skin and soft tissues, stomach, biliary tract, blood and the brain. It can also be used prophylactically to manage bacterial infections following surgical or diagnostic procedures.
CEKOZEF S 1.5 INJECTION should be under careful medical supervision. Therapy with CEKOZEF S 1.5 INJECTION should be continued for the stipulated duration as instructed by the doctor to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control.
Before receiving CEKOZEF S 1.5 INJECTION inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any stomach problems (diarrhea, colitis) or if are weak or malnourished as a precaution.
Talk to your doctor before receiving CEKOZEF S 1.5 INJECTION if you are pregnant or breastfeeding. Avoid consumption of alcohol while receiving CEKOZEF S 1.5 INJECTION as it may lead to unwanted reactions.
The most common side effects of receiving CEKOZEF S 1.5 INJECTION are pain and swelling at the site of injection, diarrhea, vomiting and anemia. Consult your doctor if any of these side effect worsens.
Uses Of CEKOZEF S 1.5 INJECTION
It is used to manage bacterial infections such as:
- Blood infections (such as bacteraemia or sepsis including sepsis in new-borns)
- Urinary tract infections (such as cystitis and pyelonephritis)
- Genital tract infections (Ex. gonorrhoea, endometriosis, pelvic inflammation)
- Skin and soft tissue infections (such as abscesses, furunculosis, impetigo, erysipelas)
- Stomach and biliary tract infections (such as peritonitis, cholecystitis, intra-abdominal abscess)
- Respiratory tract infections (Ex. pneumonia, cystic fibrosis, chronic bronchitis)
- Bone and joint infections (Ex. septic arthritis)
- Brain infections (Ex. meningitis and ventriculitis)
- Heart infections (Ex. endocarditis)
- Post-surgical infections
How CEKOZEF S 1.5 INJECTION Works
CEKOZEF S 1.5 INJECTION is a powerful antibacterial agent. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis. Unlike other antibiotics, it can also remain unaffected by the toxic proteins produced by the bacteria (such as beta lactamases). As a result, it destroys the susceptible bacteria and manages it from further growth and multiplication which will reduce the severity of the infection.
How to use CEKOZEF S 1.5 INJECTION
CEKOZEF S 1.5 INJECTION will be given to you only by a doctor or a nurse into a vein (intravenously) or into the muscle (intramuscularly).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
Side Effects Of CEKOZEF S 1.5 INJECTION
Common
- injection site reactions (pain, inflammation and swelling)
- skin rash, itching
- diarrhoea, vomiting
- anemia (low RBC in blood)
- low WBC and platelet count in blood
- positive coombs test (a blood test)
- increased liver enzymes
Uncommon
- fever
Rare
Contact your doctor if you notice any of the following symptoms after receiving CEKOZEF S 1.5 INJECTION:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- severe uncontrollable watery diarrhoea, feeling weak and fever
- increased bleeding tendency
How To Manage Side Effects
Vomiting:
Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if you experience severe vomiting.
Diarrhea:
Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens, contact your doctor immediately.
Skin rash:
Avoid hot showers because hot water can irritate your skin further. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Consult your doctor if your skin rash worsens.
Injection site reactions:
Place an ice pack at the site of injection. Do not move the affected area. Consult your doctor if the symptom worsens.
Warning & Precautions
Pregnancy
CEKOZEF S 1.5 INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor for advice before receiving it.
Breastfeeding
CEKOZEF S 1.5 INJECTION should be used with caution among breastfeeding women. Therefore, consult your doctor before receiving it.
Driving and Using Machines
Do not drive and operate any heavy tools or machines if your ability is affected by CEKOZEF S 1.5 INJECTION.
Alcohol
Avoid consumption of alcohol while receiving CEKOZEF S 1.5 INJECTION as it may cause unpleasant reactions.
Kidney
CEKOZEF S 1.5 INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
Liver
CEKOZEF S 1.5 INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.
Allergy
Talk to your doctor before receiving CEKOZEF S 1.5 INJECTION if you are allergic to Cefoperazone or to any other beta-lactam antibiotics (Ex. amoxicillin)
Others
Before receiving CEKOZEF S 1.5 INJECTION inform your doctor if you:
- have severe persistent diarrhea
- are malnourished
- are an alcoholic
- are receiving nutrients through IV fluids instead of oral foods
- have any stomach problems (such as colitis)
- are going to have any blood tests (such as Coombs test)
- are going to have any urine tests (such as urine glucose tests)
Use in paediatrics:
The safety and effectiveness of CEKOZEF S 1.5 INJECTION have not been established in children and adolescents (aged below 18 years). Therefore, consult your doctor for advice.
Use in geriatrics:
CEKOZEF S 1.5 INJECTION should be used with caution in the elderly patients. Therefore, consult your doctor for advice before receiving it.
Interactions
A. Drug – Drug interactions
Before receiving CEKOZEF S 1.5 INJECTION inform your doctor if you are taking the following medicines such as:
- aminoglycoside antibiotics (used to manage bacterial infections) Ex. gentamycin, streptomycin
- alcohol containing medicines (such as cough syrups)
Overdosage
CEKOZEF S 1.5 INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual side effects.
Synopsis
| Drug | : | Cefoperazone |
| Pharmacological Category | : | Cephalosporins |
| Therapeutic Indication | : | Bacterial Infections |
| Dosage Forms | : | Injection |
More Information
- keep CEKOZEF S 1.5 INJECTION out of reach of children
- store CEKOZEF S 1.5 INJECTION at room temperature
FAQs About CEKOZEF S 1.5 INJECTION
What is the use of CEKOZEF S 1.5 INJECTION?
CEKOZEF S 1.5 INJECTION is used to manage bacterial infections of the respiratory tract, urinary tract, genital tract, skin and soft tissues, stomach, biliary tract, blood and the brain. It can also be used prophylactically to manage bacterial infections following surgical or diagnostic procedures.
How CEKOZEF S 1.5 INJECTION works in my body?
CEKOZEF S 1.5 INJECTION is a bactericidal agent. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis that is essential for the bacterial cell to survive. This action destroys the susceptible bacteria, manage their further growth and multiplication and reduce the severity of the infection.
Can CEKOZEF S 1.5 INJECTION be used in patients with kidney problems?
CEKOZEF S 1.5 INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
How CEKOZEF S 1.5 INJECTION is administered?
CEKOZEF S 1.5 INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously) or into the muscles (intramuscularly).
For how long should I take CEKOZEF S 1.5 INJECTION?
Take CEKOZEF S 1.5 INJECTION for the stipulated duration as prescribed by your doctor. Do not skip the medicine or stop receiving it on your own as it may cause the infection to become severe.
Can CEKOZEF S 1.5 INJECTION be given to pregnant women?
CEKOZEF S 1.5 INJECTION should be used in pregnant women only if it is considered necessary by the physician. Therefore, consult your doctor for advice before receiving it.
What precautions should I follow while receiving CEKOZEF S 1.5 INJECTION?
Before receiving CEKOZEF S 1.5 INJECTION inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any stomach problems (diarrhea, colitis) or if are weak or malnourished as a precaution. Talk to your doctor before receiving CEKOZEF S 1.5 INJECTION if you are pregnant or breastfeeding. Avoid consumption of alcohol while receiving CEKOZEF S 1.5 INJECTION are it may lead to unwanted reactions.
What are the common side effects of receiving CEKOZEF S 1.5 INJECTION?
The most common side effects of receiving CEKOZEF S 1.5 INJECTION are pain and swelling at the site of injection, diarrhea, vomiting and anemia. Consult your doctor if any of these side effect worsens.
Can I stop receiving CEKOZEF S 1.5 INJECTION once my symptoms subside?
Do not stop receiving CEKOZEF S 1.5 INJECTION once your symptoms subside. It is important to take the full course of CEKOZEF S 1.5 INJECTION to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.
Can the use of CEKOZEF S 1.5 INJECTION cause diarrhea?
CEKOZEF S 1.5 INJECTION may cause diarrhea in some individuals. If you experience diarrhea, drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens contact your doctor immediately.
What kind of infections that CEKOZEF S 1.5 INJECTION can manage?
CEKOZEF S 1.5 INJECTION is an antibiotic. It is used to manage infections caused by bacteria. It kills harmful bacteria by binding to the bacterial cell and interfering with cell wall synthesis. It can manage bacterial infections of the respiratory tract, urinary tract, genital tract, stomach, brain, blood and skin or soft tissues.
Is CEKOZEF S 1.5 INJECTION a steroid?
No. CEKOZEF S 1.5 INJECTION is an antibiotic and not a steroid medicine.
Can CEKOZEF S 1.5 INJECTION manage viral infections?
No. CEKOZEF S 1.5 INJECTION cannot manage viral infections. It manages only bacterial infections. It acts by killing the susceptible bacteria which are responsible for causing infections, and therefore not effective against any viral infections.
References
1. KD. Tripathi. Beta-lactam Antibiotics. Essentials of Medical Pharmacology. 7th edition. 2013. Page – 728.
2. R N Brogden, A Carmine, R C Heel, P A Morley, T M Speight, G S Avery. Cefoperazone: A review of its in vitro antimicrobial activity, pharmacological properties and therapeutic efficacy. NIH. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. December 1981. [Accessed on 3rd December 2022] https://pubmed.ncbi.nlm.nih.gov/6459224/
3. Pfizer Inc. U.S. Food and Drug Administration. [Revised in March 2015]. [Accessed on 3rd December 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
4. Pfizer Inc. Cefoperazone Sodium. [Revised in February 2017]. [Accessed on 3rd December 2022] https://www.pfizerpro.com.my/sites/default/files/lpd_cefoperazone_sodium_-_cefobid_-_mys_-_english.pdf
5. Leeford Healthcare Ltd. Cefaprex 1g Injection. [Accessed on 3rd December 2022] https://www.leeford.in/product/1447/cefaprex-1-g
Useful Diagnostic Tests
- Complete Blood Count
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