INTRODUCTION ABOUT CASPOGIN 50MG INJECTION

CASPOGIN 50MG INJECTION contains Caspofungin which belongs to the group of medicines called Antifungal Drugs. It is used to manage serious fungal infections of the blood, heart, brain, eyes, bones, nose, sinuses, lungs and other parts of the body (such as invasive candidiasis, invasive aspergillosis, etc.).

It can also be used to manage fungal infections during high-risk conditions such as after a surgery or chemotherapy and in patients who recently underwent an organ transplantation or having a weak immune system. It may be given to patients to reduce fever and chills that is suspected to be a fungal infection when management with antibiotics is not working appropriately.

CASPOGIN 50MG INJECTION should be used under careful medical supervision. It is suitable for use both in adults and in children. Talk to your doctor before receiving CASPOGIN 50MG INJECTION if you have any liver problems or taking immunosuppressants (such as ciclosporin or tacrolimus) as a precaution.

Inform your doctor before receiving CASPOGIN 50MG INJECTION if you are pregnant, think you may be pregnant or planning to become pregnant. CASPOGIN 50MG INJECTION is not recommended for use in breastfeeding women.

The most common side effects of receiving CASPOGIN 50MG INJECTION are pain, swelling, irritation and redness at the site of injection, headache, fast heartbeat, flushing, fever, chills, shortness of breath, joint pain, leg pain, back pain, changes in taste, constipation and dry mouth. Consult your doctor if any of these side effect worsens.

USES OF CASPOGIN 50MG INJECTION

Manage and manages serious fungal infections (such as invasive candidiasis, invasive aspergillosis, etc.)

HOW CASPOGIN 50MG INJECTION WORKS

CASPOGIN 50MG INJECTION is an antifungal medication. It acts by disrupting the fungal cell wall by blocking the actions of certain cellular proteins (beta-glucan) which is essential for the fungal cell to maintain the rigid cell structure. As a result, it makes the fungal cells weak and fragile and eventually destroys them, thereby reducing the severity of infection and managing it from spreading further.

DIRECTIONS FOR USE

CASPOGIN 50MG INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously). Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of infection.

SIDE EFFECTS OF CASPOGIN 50MG INJECTION

COMMON

headache
fast heartbeat
flushing, low blood pressure
increased liver enzymes
skin rash, itching and redness, sweating
injection site reactions (pain, inflammation, itching, redness, swelling)
fever, chills
low RBC, WBC count in blood
low blood albumin levels
low potassium levels in the blood
shortness of breath
nausea, vomiting, diarrhoea
joint pain

UNCOMMON

loss of appetite, swelling of body parts
high blood sugar levels
changes in blood calcium levels (high or low)
low blood magnesium levels
increase in acid level in the blood
nervousness, disorientation, lack of sleep
dizziness, numbness, shakiness, sleepiness
changes in taste
blurred vision, watery eyes, swollen eyelids, yellow eyes
abnormal heart rate (fast or slow)
high blood pressure, pain, redness and swelling of legs
shortness of breath, chest tightness
nasal congestion, cough, throat pain
stomach pain, bloating, constipation, difficulty in swallowing, swollen abdomen
dry mouth
back pain, pain in arms or legs, bone pain, muscle pain, muscle weakness
liver problems or kidney problems
tiredness

RARE

Contact your doctor immediately if you experience any of the following side effects:

severe allergic reaction (such as skin rash, itching, swelling of the face, tongue, throat with difficulty in breathing or swallowing)
cough and breathing difficulties
severe skin reactions with blisters and peeling of skin

HOW TO MANAGE SIDE EFFECTS

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Stick to simple meals and avoid oil rich or spicy foods. Consult your doctor if nausea worsens.

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

There is no proper information regarding the use of CASPOGIN 50MG INJECTION in pregnant women. Therefore, it should be used in pregnant women only if considered necessary by the physician.

BREASTFEEDING

Contraindicated

CASPOGIN 50MG INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.

DRIVING AND USING MACHINES

Use with Caution

Do not drive or operate any heavy tools or machines if your ability is affected by CASPOGIN 50MG INJECTION.

LIVER

Use with Caution

CASPOGIN 50MG INJECTION should be used with caution in patients with liver problems. Therefore, consult your doctor before receiving it.

ALLERGY

Contraindicated

Tell your doctor before receiving CASPOGIN 50MG INJECTION if you are allergic to Caspofungin or to any other ingredients of this medicine.

OTHERS

Use in pediatrics:

CASPOGIN 50MG INJECTION should be used with caution in children and adolescents (aged below 18 years). Therefore, consult your doctor before receiving it.

Use in geriatrics:

CASPOGIN 50MG INJECTION can be used with caution in elderly patients. Therefore, consult your doctor before receiving it.

INTERACTIONS

A. Drug-Drug interactions:

Before receiving CASPOGIN 50MG INJECTION, inform your doctor if you are taking any of the following medicines:

cyclosporin or tacrolimus (medicines used to manage rejection of organ transplant or cause immune system suppression)
efavirenz or nevirapine (used to manage HIV)
phenytoin or carbamazepine (medicines used to manage seizures)
dexamethasone (steroid medicine used to manage inflammations)
rifampicin (an antibiotic used to manage tuberculosis)

Overdosage:

CASPOGIN 50MG INJECTION will be given to you only by a doctor or nurse in a hospital, and so it is unlikely to receive an overdose. However, if you are worried that you may have been given too much of CASPOGIN 50MG INJECTION, Contact your doctor immediately.

SYNOPSIS

Drug	:	Caspofungin
Pharmacological Category	:	Echinocandins
Therapeutic Indication	:	Fungal infections
Dosage Forms	:	Injection

MORE INFORMATION

Keep CASPOGIN 50MG INJECTION out of reach of children
Store CASPOGIN 50MG INJECTION in a refrigerator between 2-8°C

FAQs ABOUT CASPOGIN 50MG INJECTION

Q: What is CASPOGIN 50MG INJECTION used for?

A: CASPOGIN 50MG INJECTION is used to manage serious fungal infections of the blood, heart, brain, eyes, bones, nose, sinuses, lungs and other parts of the body (such as invasive candidiasis, invasive aspergillosis, etc.). It can also be used to manage fungal infections during high-risk conditions such as after a surgery or chemotherapy and in patients who recently underwent an organ transplantation or having a weak immune system.

Q: Is CASPOGIN 50MG INJECTION an antibiotic?

A: No. CASPOGIN 50MG INJECTION is an antifungal medicine that acts by making the fungal cells fragile and terminating their growth. Thereby it stops the spread of infection and allows the natural defense mechanism of the body a time to totally eradicate the infection.

Q: Does CASPOGIN 50MG INJECTION affect liver?

A: CASPOGIN 50MG INJECTION may unusually cause decreased bile flow, enlarged liver, liver disorder or injury, and yellowing of the skin and whites of the eyes. Therefore, caution should be taken if you have ever had liver problems. Therefore, consult your doctor before receiving it.

Q: What are the side effects of CASPOGIN 50MG INJECTION?

A: The most common side effects of receiving CASPOGIN 50MG INJECTION are pain, swelling, irritation and redness at the site of injection, headache, fast heartbeat, flushing, fever, chills, shortness of breath, joint pain, leg pain, back pain, changes in taste, constipation and dry mouth. Consult your doctor if any of these side effect worsens.

Q: Can a person taking CASPOGIN 50MG INJECTION breastfeed?

A: CASPOGIN 50MG INJECTION is not recommended for use in breastfeeding women. Therefore, consult your doctor before receiving it.

Q: How long should I receive CASPOGIN 50MG INJECTION?

A: You need to receive therapy with CASPOGIN 50MG INJECTION for the stipulated duration prescribed by your doctor. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.

Q: Is CASPOGIN 50MG INJECTION safe?

A: CASPOGIN 50MG INJECTION is safe at doses prescribed by the physician. Therefore, do not alter the dose of CASPOGIN 50MG INJECTION without consulting your doctor.

Q: Can I stop receiving CASPOGIN 50MG INJECTION without consulting your doctor?

A: No. You should not stop receiving CASPOGIN 50MG INJECTION without consulting your doctor as it may reduce its effectiveness. Therefore, receive CASPOGIN 50MG INJECTION for the stipulated duration recommended by your doctor to achieve maximum results.

REFERENCES

1. KD. Tripathi. Antifungal Drugs. Essentials of medical pharmacology. Eighth edition. 2013. Page – 841.

2. Laurena N. Dongmo Fotsing; Tushar Bajaj. Caspofungin. StatPearls. National Library of Medicine. National center for biotechnology information. October 2022. [Accessed on 30th January 2023] https://www.ncbi.nlm.nih.gov/books/NBK545140/

3. Staci A Pacetti, Steven P Gelone. Caspofungin acetate for treatment of invasive fungal infections. National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2003. [Accessed on 30th January 2023] https://pubmed.ncbi.nlm.nih.gov/12503942/

4. FAREVA Mirabel. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 30th January 2023] https://www.medicines.org.uk/emc/files/pil.2226.pdf

5. Pharmadox healthcare Ltd. Electronic Medicines Compendium (EMC). [Revised in November 2022] [Accessed on 30th January 2023] https://www.medicines.org.uk/emc/files/pil.2722.pdf

6. Gufic Biosciences Limited. Cipla Ltd. [Revised in October 2021]. [Accessed on 30th January 2023] https://ciplamed-library.com/content/caspogin-injection

7. Merck Sharp & Dohme B. V. European Medicines Agency. [Revised in September 2011]. [Accessed on 30th January 2023] https://www.ema.europa.eu/en/documents/product-information/cancidas-epar-product-information_en.pdf

USEFUL DIAGNOSTIC TESTS

Antigen Testing
Serological Testing
PCR-Based Assays

AUTHOR DETAILS

Written By Srilekha. R - B.Pharm

Last updated on 01 Feb 2023 | 11:01 AM(IST)

Caspogin 50mg Injection 10ml

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