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Introduction About CARVDOL 12.5 TABLET
CARVDOL 12.5 TABLET is a cardiac medicine used in the management of hypertension, angina and congestive heart failure. It contains a medicine called Carvedilol which is a beta-blocker that works by improving heart functions and reduces strain of the heart.
Take this medicine at the same time each day as directed by your physician. Swallow the medicine with a glass of water after meals. Do not stop taking CARVDOL 12.5 TABLET without consulting your doctor.
Before taking CARVDOL 12.5 TABLET, inform your doctor if you have asthma or breathing difficulties, severely low blood pressure, liver problems, kidney problems, diabetes, thyroid problems, poor blood circulation in the body, cold hands and feet, phaeochromocytoma or problems in adrenal gland. Do not take CARVDOL 12.5 TABLET without consulting your doctor if you are pregnant or breastfeeding.
The most common side effects of taking CARVDOL 12.5 TABLET are dizziness, headache, tiredness, weakness, low blood pressure, diarrhea, stomach pains, constipation, tingling and numbness, fluid retention, weight gain or increased blood sugar and cholesterol levels. Consult your doctor if any of these side effect worsens or experience severe chest pains, low sugar levels or passing less urine with swelling in hands, feet and body parts.
Uses Of CARVDOL 12.5 TABLET
CARVDOL 12.5 TABLET is used in the management of the following heart conditions:
- Hypertension
- Angina
- Congestive heart failure
How CARVDOL 12.5 TABLET Works
CARVDOL 12.5 TABLET contains a medicine called Carvedilol which is a beta-blocker that works by blocking both beta and alpha receptors on blood vessels and the heart.
For hypertension, carvedilol blocks beta-1 receptors in the heart, which slows the heart rate and reduces the force of heart contractions, lowering blood pressure. It also blocks alpha-1 receptors on blood vessels, causing them to relax and widen, which further reduces blood pressure.
For angina (chest pain), carvedilol decreases the workload on the heart by reducing the heart rate and lowering blood pressure, which helps improve oxygen supply to the heart muscle and relieves chest pain.
In heart failure, carvedilol’s effects on both beta and alpha receptors reduce strain on the heart, improve heart function over time, and help prevent worsening of symptoms by protecting the heart muscle from stress and damage.
How to use CARVDOL 12.5 TABLET
- Take CARVDOL 12.5 TABLET as advised by your physician.
- Swallow the medicines with a glass of water.
- Do not crush or chew the medicine.
- Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of CARVDOL 12.5 TABLET
Common Side Effects of CARVDOL 12.5 TABLET:
- Headache, dizziness, tiredness, weakness
- Low blood pressure especially after standing up, slow heartbeat
- Swelling of arms and legs
- Infections of upper respiratory tract or urinary tract
- Anaemia
- Fluid retention and weight gain
- Increase in cholesterol levels
- Abnormal blood sugar levels
- Feeling depressed
- Vision problems, sore or dry eyes
- Poor blood circulation in your arms and legs, tingling and pain in your fingers and a pain in your leg which gets worse when you walk
- Nausea, vomiting, diarrhea, stomach pains, indigestion, constipation
- Breathing problems
- Hair loss
- Being unable to get an erection (erectile dysfunction)
Stop taking CARVDOL 12.5 TABLET and consult your doctor immediately if you experience any of the following side effects:
- chest pain accompanied by shortness of breath, sweating and feeling sick
- decreased urination often with swelling of legs (indicates problems with kidneys)
- low blood sugar (hypoglycaemia) which may lead to seizures or unconsciousness
Warning & Precautions
Pregnancy
Monitoring requiredCARVDOL 12.5 TABLET should be used in pregnant women only if it is considered necessary by the physician.
Breastfeeding
ContraindicatedCARVDOL 12.5 TABLET is generally not recommended for use in breastfeeding women as it is not known if this medicine passes into breast milk.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsy after taking CARVDOL 12.5 TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking CARVDOL 12.5 TABLET because it might make you dizzier.
Kidney
ContraindicatedCARVDOL 12.5 TABLET is not recommended for use in patients with kidney problems.
Liver
ContraindicatedCARVDOL 12.5 TABLET is not recommended for use in patients with liver problems.
Allergy
ContraindicatedDo not take CARVDOL 12.5 TABLET if you are allergic to Carvedilol or any of the other ingredients of this medicine.
Lungs
ContraindicatedCARVDOL 12.5 TABLET is not recommended for use in patients with breathing problems such as asthma or other lung diseases.
Heart Disease
ContraindicatedCARVDOL 12.5 TABLET is not recommended for use in patients having severe heart failure, conduction defect of the heart or heart block, AV heart block grade II or III, sick sinus syndrome (sino-atrial block), slow heartbeat, cardiogenic shock, very low blood pressure, unstable heart failure, Prinzmetal’s angina (chest pain at rest).
Use In Pediatrics
ContraindicatedCARVDOL 12.5 TABLET is generally not recommended for use in children and adolescents under 18 years of age.
Use In Geriatrics
Use with CautionCARVDOL 12.5 TABLET should be used with caution in elderly patients aged above 65 years.
Others
CARVDOL 12.5 TABLET is not recommended for use if you have:
- severe hardening of arteries affecting the circulation in legs or feet
- unmanageed pheochromocytoma
- metabolic acidosis
- glucose or galactose intolerance
- receiving diltiazem or verapamil injection or infusion
Before taking CARVDOL 12.5 TABLET, inform your doctor if you have:
- diabetes
- Raynaud’s syndrome (poor circulation affecting hands, feet or lower legs causing cold hands and feet or pain)
- Raynaud’s syndrome (cold feet and hands) or peripheral vascular disease causing cold hands and feet)
- thyroid problems
- previous history of a serious allergic reaction
- desensitisation therapy
- psoriasis
- wear contact lenses (as they may cause dry eyes)
- surgery
- taking other antihypertensives like debrisoquine
Interactions
A. Drug-Drug interactions:
Before taking CARVDOL 12.5 TABLET, inform your doctor if you are taking any of the following medicine:
- antidiabetics (Ex. insulin, metformin)
- antidepressants (Ex. moclobemide, reserpine, amitriptyline, fluoxetine, paroxetine, isocarboxide, phenelzine, phenothiazines, haloperidol)
- cardiovascular agents (Ex. clonidine, doxazosin, terazosin, amiodarone, diltiazem, verapamil, amlodipine, nifedipine)
- atracurium besilate (medicines used to relax muscles and also used in anaesthesia)
- corticosteroids Ex. prednisolone
- cimetidine (medicines used to manage ulcers)
- erythromycin (used to manage infections)
- medicines used to manage cough and cold (Ex. ephedrine or pseudoephedrine)
- medicines used for migraine (Ex. clonidine, ergotamine)
- ketoconazole (antifungals)
- amylobarbitone (to induce sleep)
- prochlorperazine (antiemetics)
- cyclosporine (a medicine used after organ transplantation)
- non-steroidal anti-inflammatory drugs. Ex. ibuprofen, diclofenac
- medicines used for hormone replacement therapy (Ex. oestrogens) or contraceptive pills
- rifampicin (anti tuberculosis)
- beta-agonist bronchodilators
Overdosage:
If you or anyone else accidentally take too much of CARVDOL 12.5 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are dizziness, faintness, sick, breathlessness or wheezy, very drowsy or experience convulsions.
Synopsis
| Drug | : | Carvedilol |
| Pharmacological Category | : | Beta-blockers |
| Therapeutic Indication | : | Hypertension, Angina pectoris and Congestive heart failure |
| Dosage Forms | : | Tablet |
More Information
To know more about this medicine:
FAQs About CARVDOL 12.5 TABLET
Q: What is CARVDOL 12.5 TABLET used for?
A: CARVDOL 12.5 TABLET is a heart medicine used in the management of high blood pressure, angina (chest pain) and heart failure.
Q: Does CARVDOL 12.5 TABLET cause weight gain?
A: Yes. CARVDOL 12.5 TABLET may cause weight gain, as it may cause fluid retention in the body. Practising regular exercise can reduce this. If you experience significant weight gain with swelling of legs and arms consult your doctor immediately.
Q: What are the side effects of taking CARVDOL 12.5 TABLET?
A: The most common side effects of taking CARVDOL 12.5 TABLET are dizziness, headache, tiredness, weakness, low blood pressure, diarrhea, stomach pains, constipation, tingling and numbness, fluid retention, weight gain or increased blood sugar and cholesterol levels. Consult your doctor if any of these side effect worsens or experience severe chest pains, low sugar levels or passing less urine with swelling in hands, feet and body parts.
Q: Does CARVDOL 12.5 TABLET cause shortness of breath?
A: Yes. CARVDOL 12.5 TABLET may cause shortness of breath. If you experience any unusual symptoms like chest pain, shortness of breath, dizziness, headache, sweating etc. Stop taking CARVDOL 12.5 TABLET and Contact your doctor immediately.
Q: Does CARVDOL 12.5 TABLET cause heart palpitations?
A: Yes. CARVDOL 12.5 TABLET cause heart palpitations. If you feel any unusual symptoms like pounding, fluttering or skipped heartbeats.
Q: Can I use CARVDOL 12.5 TABLET in pregnancy?
A: CARVDOL 12.5 TABLET should be used in pregnant women only if it is considered necessary by the physician.
Q: How does CARVDOL 12.5 TABLET work?
A: CARVDOL 12.5 TABLET works by blocking Beta receptors (Beta-1 and Beta- 2) and alpha1 receptors causing relaxation of blood vessels. This makes it easier for the heart to pump blood around the body and reduces blood pressure and strain on your heart. It has also a calcium channel blockade effect in high doses, antioxidant/ free radical scavenging properties.
Q: How to take CARVDOL 12.5 TABLET?
A: Take CARVDOL 12.5 TABLET as advised by your physician. Swallow the medicines with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition
References
1. Barbara G. wells, Terry L. schwinghammer, Joseph T. dipiro, Cecily V. dipiro. Hypertension, Heart failure. Pharmacotherapy handbook. Tenth edition. 2017. Page – 120, 140.
2. KD. Tripathi. Antiadrenergic drugs and drugs for glaucoma, cardiovascular drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 151, 564.
3. KRKA, d.d. Health Products Regulatory Authority (HPRA). [Accessed on 5th November 2024] click here
4. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC). [Revised on December 2019] [Accessed on 5th November 2024] click here
5. GlaxoSmithKline. U.S. Food & Drug Administration. [Revised on February 2005] [Accessed on 5th November 2024] click here
6. Teva UK limited. Carvedilol. [Revised on October 2021] [Accessed on 5th November 2024] click here
7. Sun Pharmaceutical Industries, Inc. Carvedilol. [Revised on September 2017] [Accessed on 5th November 2024] click here
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