Brufit OD Tablet 10'S

Introduction About BRUFIT OD TABLET

BRUFIT OD TABLET contains Flupirtine which belongs to a group of medicines called Nonopioid, Non-NSAID analgesics. It is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).  

BRUFIT OD TABLET is not recommended for use in patients with liver problems. Before taking BRUFIT OD TABLET, inform your doctor if you have kidney disease, myasthenia gravis, had or have a history of tinnitus (ringing in the ears) or if you are allergic to Flupirtine. BRUFIT OD TABLET is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor.

BRUFIT OD TABLET is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary and it should be used with caution in elderly patients, especially in patients with kidney problems. The most common side effects of taking BRUFIT OD TABLET are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, constipation and diarrhea. Consult your doctor if any of the side effects worsen.

Uses Of BRUFIT OD TABLET

• Manage acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles)

How BRUFIT OD TABLET Works

BRUFIT OD TABLET works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage and hence it is useful in providing relief from pain, including that is associated with muscle tension.

How to use BRUFIT OD TABLET

Take BRUFIT OD TABLET as advised by your physician. Swallow the medicine with a glass of water and do not chew or crush the medicine. Your doctor will decide the correct dose and duration for you depending upon your age and body weight.

Side Effects Of BRUFIT OD TABLET

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly. If the symptom does not improve, consult your doctor.

Diarrhea

Drink lot of fluids, such as water to keep yourself hydrated. Avoid eating high-fat or spicy foods. Try to avoid taking any medicine on your own to manage diarrhea and consult your doctor if the symptom gets worse.

Dry Mouth

Sip water regularly and other sugar free liquids. Do not use mouthwashes that contain alcohol because they can make your mouth dry, use mouthwash that is used only for dry mouth. Limit your caffeine intake. Avoid smoking or using tobacco products. Consult your doctor if the symptom does not improve.

Headache

Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.

Nausea And Vomiting

Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Inform your doctor if the symptom does not improve.

Warning & Precautions

Pregnancy

Monitoring required

BRUFIT OD TABLET is not recommended during pregnancy unless considered clearly necessary. Consult your doctor before taking BRUFIT OD TABLET.

Breastfeeding

Monitoring required

BRUFIT OD TABLET is not recommended in breastfeeding women unless considered clearly necessary. Consult your doctor before taking BRUFIT OD TABLET.

Driving and Using Machines

Use with Caution

Do not drive or operate any machines if you feel dizzy or sleepy after taking BRUFIT OD TABLET.

Alcohol

Consult your doctor

Avoid consuming alcohol while taking BRUFIT OD TABLET as it may increase the risk of liver problems.

Kidney

Use with Caution

BRUFIT OD TABLET should be used with caution in patients with kidney diseases. Consult your doctor for advice before taking BRUFIT OD TABLET.

Liver

Contraindicated

BRUFIT OD TABLET is not recommended for use in patients with liver problems. Consult your doctor for advice before taking BRUFIT OD TABLET.

Allergy

Contraindicated

BRUFIT OD TABLET is not recommended for use if you are allergic to flupirtine.

Use In Pediatrics

Contraindicated

BRUFIT OD TABLET is not recommended for use in children and adolescents (below 18 years of age) unless deemed necessary. Consult your child’s doctor for advice.

Use In Geriatrics

Use with Caution

BRUFIT OD TABLET should be used with caution in elderly patients, especially in patients with any kidney problems. Consult your doctor for advice before taking BRUFIT OD TABLET.

Interactions

A. Drug-Drug interactions:

Before taking BRUFIT OD TABLET, inform your doctor, if you are taking any of the following medicines:

• Medicines that manage or manages blood clot (Ex. warfarin, dicumarol)
• Paracetamol (used to reduce fever and inflammation)
• Carbamazepine (used to manage epilepsy)
• Diazepam (used to manage anxiety and alcohol withdrawal)

Overdosage:

If you or anyone else accidentally takes too much of BRUFIT OD TABLET, consult your doctor immediately or visit the nearby hospital.  

Synopsis

More Information

FAQs About BRUFIT OD TABLET

Q: What is BRUFIT OD TABLET used for?

A: BRUFIT OD TABLET is used in the management of acute and chronic pain (such as primary headache, tumor pain, menstrual cramps, pain after traumatologic/orthopaedic operations and injuries and painful increased muscle tone of the posture and motor muscles).

Q: What common side effects are seen with BRUFIT OD TABLET?

A: The most common side effects of taking [GBNKEYWORD are fatigue, dizziness, heartburn, nausea, vomiting, dry mouth, diarrhoea, constipation, diarrhea, stomach upset, bloating and pain, loss of appetite, tremor, headache, increased sweating, sleep problems and restlessness. Consult your doctor if any of the side effects worsen.

Q: How does BRUFIT OD TABLET work?

A: BRUFIT OD TABLET works by managing the transmission of pain signals by blocking neuronal excitability and reducing the calcium influx into the cells that is responsible for the sense of pain and inflammation produced at the site of injury and damage, and hence it is useful in providing relief from pain, including that is associated with muscle tension.

Q: Can BRUFIT OD TABLET be used in pregnant women?

A: BRUFIT OD TABLET is not recommended for use in pregnant women unless clearly advised by the doctor. Consult your doctor before taking BRUFIT OD TABLET if you are pregnant or planning to get pregnant.

Q: Is BRUFIT OD TABLET safe to use in patients with kidney diseases?

A: BRUFIT OD TABLET should be used with caution in patients with kidney diseases. Your doctor may regularly monitor your kidney function before and during management with BRUFIT OD TABLET to manage the risk of kidney damage. Consult your doctor for advice before taking BRUFIT OD TABLET.

References

1. KD. Tripathi. Opioid Analgesics and Antagonists. Essentials of medical pharmacology. Seventh edition. 2013. Page – 469- 486.

2. Harish S, Bhuvana K, Bengalorkar GM, Kumar T. Flupirtine: Clinical pharmacology. Journal of Anaesthesiology and Clinical Pharmacology. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339720/

3. Singal R, Gupta P, Jain N, Gupta S. Role of flupirtine in the treatment of pain - chemistry and its effects. Journal of Clinical medicine. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. June 2012. [Accessed on 21st June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557425/

4. Kim Lawson. Pharmacology and clinical applications of flupirtine: Current and future options. World Journal of Pharmacology. January 2019. [Accessed on 21st June 2022] https://www.wjgnet.com/2220-3192/full/v8/i1/1.htm

Useful Diagnostic Tests

• Liver function test
• Kidney function test

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)

Last updated on 01 Aug 2024 | 04:58 PM(IST)