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Introduction About BRO ZEDEX SF EXPECTORANT
BRO ZEDEX SF EXPECTORANT is a combination of Bromhexine, Guaiphenesin and Terbutaline which belongs to the group of medicines called Mucolytics, Expectorant and Beta-agonist respectively. It is used in the management of productive cough when associated with bronchospasm in conditions such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema.
Bronchitis is an inflammation in the airway of the lungs which carry air to and from lungs. Chronic obstructive pulmonary disease (COPD) is a lung disease causing obstruction in the airway. Bronchiectasis is a condition where the airways of lungs become wide allowing the accumulation of mucus deposition making it prone to infections. Emphysema is a lung disease causing shortness of breath. BRO ZEDEX SF EXPECTORANT should be used with caution in patients with high blood pressure, heart diseases such as arrhythmias, coronary insufficiency, uncontrolled diabetes mellitus, low levels of serum potassium, peptic ulcer and patients with high levels of thyroid and seizures.
Safety of BRO ZEDEX SF EXPECTORANT has not been studied in pregnancy and lactation. Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it. The most common side effects of BRO ZEDEX SF EXPECTORANT are tremors, nervousness, headache, drowsiness, vomiting, nausea, sweating, muscle cramps, hypersensitivity, rash, shortness of breath, chest discomfort, weakness, anxiety, and dry mouth. Consult your doctor if any of the above side effects worsen or persists for a longer duration.
Uses Of BRO ZEDEX SF EXPECTORANT
It is used to manage productive cough when associated with bronchospasm in conditions such as:
- bronchitis
- bronchial asthma
- chronic obstructive pulmonary disease (copd)
- bronchiectasis
- emphysema
How BRO ZEDEX SF EXPECTORANT Works
BRO ZEDEX SF EXPECTORANT is a combination of Bromhexine, Guaiphenesin and Terbutaline. Bromhexine liquifies thick, tenacious sputum. Viscosity of sputum is reduced by dissolving mucopolysaccharide fibres and also improves mucociliary clearance of secretions. Guaiphenesin increases the output of sputum and bronchial secretions by reducing adhesiveness and surface tension. By increasing the volume of bronchial secretions, it reduces the viscosity of tenacious sputum. Terbutaline is a directly acting sympathomimetic agent with selective b2 stimulant effect which helps to alleviate bronchospasm associated with cough.
How to use BRO ZEDEX SF EXPECTORANT
Take BRO ZEDEX SF EXPECTORANT as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of BRO ZEDEX SF EXPECTORANT
Common
- tremors
- nervousness
- headache
- drowsiness
- vomiting
- nausea
- sweating
- muscle cramps
- shortness of breath
- chest discomfort
- weakness
- anxiety
- dry mouth
Rare
- increased liver enzymes
- inflammation in blood vessels of skin
Stop taking BRO ZEDEX SF EXPECTORANT and contact your doctor immediately if you experience any of the following side effects:
- hypersensitivity reaction symptoms include skin rash, swelling of the face, tongue and throat that can cause great difficulty in breathing
How To Manage Side Effects
Dizziness Or Drowsiness
Sit or lie down when you feel dizzy and rest until the dizziness goes away. This can manage the possibility of losing your balance, avoid caffeine, alcohol, and tobacco, they may trigger dizziness or make it worse. Drink at least eight glass of water a day, get seven hours of sleep, and avoid stressful situations. Eat a healthful diet that consists of vegetables, fruits, and lean proteins to help manage dizziness.
Nausea And Vomiting
Drink clear or ice-cold drinks. Eat light, bland foods. Avoid fried, greasy, or sweet foods. Eat slowly and eat smaller, more frequent meals, drinking gradually larger amounts of clear liquids, avoid solid food until the vomiting episode has passed, take rest. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
Consult your doctorSafety of BRO ZEDEX SF EXPECTORANT has not been studied in pregnant women. Consult your doctor before taking it.
Breastfeeding
Consult your doctorSafety of BRO ZEDEX SF EXPECTORANT has not been studied in breastfeeding women. Consult your doctor before taking it.
Allergy
ContraindicatedDo not take BRO ZEDEX SF EXPECTORANT if you are allergic to Bromhexine, Guaiphenesin, and terbutaline or any other ingredients of this medicine.
Heart Disease
Use with CautionBRO ZEDEX SF EXPECTORANT should be used with caution in patients with high blood pressure (hypertension), heart diseases such as arrhythmias and coronary insufficiency. Consult your doctor before taking it.
Use In Pediatrics
Consult your doctorYour doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it.
Others
Before taking BRO ZEDEX SF EXPECTORANT inform your doctor if you have:
- uncontrolled diabetes mellitus
- low levels of serum potassium (hypokalaemia)
- peptic ulcer
- hyperthyroidism
- seizures
Interactions
A. Drug-Drug interactions:
Before taking BRO ZEDEX SF EXPECTORANT, inform your doctor if you are taking any of the following medicine:
- medicines used to manage inflammation (Ex. prednisolone)
- medicines used to manage breathing difficulty (Ex. caffeine, theobromine, aminophylline, theophylline)
- medicines used to manage fluid accumulation (Ex. furosemide)
- medicine used to manage severe allergic reactions (Ex. epinephrine)
Overdosage:
If you or anyone else accidentally took more of BRO ZEDEX SF EXPECTORANT, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose low blood pressure (hypotension).
Synopsis
| Drug | : | Bromhexine, Guaiphenesin, Terbutaline |
| Pharmacological Category | : | Mucolytics, Expectorant, Beta-agonist |
| Therapeutic Indication | : | Manages cough associated with bronchospasm in various conditions |
| Dosage Forms | : | Syrup, Expectorant |
More Information
- Keep BRO ZEDEX SF EXPECTORANT out of reach of children
- Store at room temperature
FAQs About BRO ZEDEX SF EXPECTORANT
Q: What is BRO ZEDEX SF EXPECTORANT used for?
A: BRO ZEDEX SF EXPECTORANT is used in the management of productive cough when associated with bronchospasm in conditions such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema.
Q: What does BRO ZEDEX SF EXPECTORANT do?
A: Bromhexine a mucolytic agent works by reducing the thickness of the sputum and promotes clearance of the secretions. Guaiphenesin is an Expectorant which promotes the sputum output. Terbutaline is a sympathomimetic agent which relives bronchospasm (narrowing of smooth muscle).
Q: What are the common side effects of BRO ZEDEX SF EXPECTORANT?
A: The most common side effects of BRO ZEDEX SF EXPECTORANT are tremor, nervousness, headache, drowsiness, vomiting, nausea, sweating, muscle cramps, hypersensitivity, rash, shortness of breath, chest discomfort, weakness, anxiety, and dry mouth.
Q: Can I take BRO ZEDEX SF EXPECTORANT for runny nose?
A: No, BRO ZEDEX SF EXPECTORANT is intended to manage productive cough associated with lung diseases causing breathing difficulties such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema Consult your doctor before taking it.
Q: Can I give BRO ZEDEX SF EXPECTORANT for my child?
A: Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it.
Q: Can we use BRO ZEDEX SF EXPECTORANT during pregnancy and breastfeeding?
A: Safety of BRO ZEDEX SF EXPECTORANT has not been studied in pregnancy and lactation. Consult your doctor before taking the medicine.
References
1. KD. Tripathi Drugs for cough and bronchial asthma Essentials of medical pharmacology. Seventh edition. 2013. page no -219, 223, 218-219.
2. Senthilraja M And Giriraj P, Reverse Phase HPLC Method For The Simultaneous Estimation Of Terbutanile Sulphate, Bromhexine HCL And Guaifenesin In Cough Syrup Asian Journal of Pharmaceutical and Clinical Research February 2011. [Accessed on 7th July 2022] https://www.researchgate.net/publication/286957596_Reverse_phase_hplc_method_for_the_simultaneous_estimation_of_terbutanile_sulphate_bromhexine_HCl_and_guaifenesin_in_cough_syrup
3. Pfizer Limited. [Revised in July 2021] [Accessed on 7th July 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=14815
4. Cachet Pharmaceuticals Pvt. Ltd U.S. Food & Drug Administration. [Accessed on 7th July 2022] https://fdaghana.gov.gh/img/smpc/Eascof-T%20Expectorant%20Liquid%20Oral%20Syrup%20(Bromhexine%20Hydrochloride,%20Terbutaline%20Sulphate%20and%20Guaifenesin).pdf
5. Torque pharmaceuticals. [Accessed on 7th July 2022] https://torex.co.in/product/torex-br-cough-syrup/
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