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Introduction About BREVIPIL ORAL SOLUTION
BREVIPIL ORAL SOLUTION is used to manage epilepsy. It contains Brivaracetam which belongs to the group of medicines called Anti-epileptics. It works by attaching itself to specific sites (SV2A) on the nerve cells’ suppresses the abnormal activity of the nerve cells in the brain and manages the spread of electrical signals that cause seizures.
BREVIPIL ORAL SOLUTION should be used with caution if you have liver problems. It is not recommended to take if you are pregnant, as the effects of this medicine on pregnancy and the unborn baby are not known. It is not recommended to breast-feed the baby while taking the medicine as it may passes into breast milk. BREVIPIL ORAL SOLUTION is not recommended for use in children under 2 years of age.
The most common side effects of taking BREVIPIL ORAL SOLUTION are feeling sleepy or dizzy, flu, feeling very tired, convulsion (a feeling of spinning), feeling and being sick and constipation, depression, anxiety, not being able to sleep, irritability, infection of nose and throat and decreased appetite or restlessness and hyperactivity (in children). Contact your doctor if any of the symptoms get worse or persist.
Uses Of BREVIPIL ORAL SOLUTION
- Used in the management of epilepsy
How BREVIPIL ORAL SOLUTION Works
Brivaracetam works by attaching itself to specific sites (SV2A) on the nerve cells’ suppresses the abnormal activity of the nerve cells in the brain and manages the spread of electrical signals that cause seizures.
How to use BREVIPIL ORAL SOLUTION
- Take BREVIPIL ORAL SOLUTION as advised by your physician
- Shake well before use
- Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition
Side Effects Of BREVIPIL ORAL SOLUTION
Common side effects of BREVIPIL ORAL SOLUTION:
- feeling sleepy or dizziness
- flu
- feeling very tired (fatigue)
- convulsion, a feeling of spinning (vertigo)
- feeling and being sick
- constipation
- anxiety not being able to sleep (insomnia)
- irritability
- infection of the nose and throat, cough
- decreased appetite
- restlessness and hyperactivity (in children)
- loss of touch with reality and/or abnormal thinking (psychotic disorder)
- being aggressive
- nervous excitement (agitation)
- self-harming thoughts
- decrease in white blood cells
Warning & Precautions
Pregnancy
ContraindicatedIt is not recommended to take if you are pregnant, as the effects of this medicine on pregnancy and the unborn baby are not known.
Breastfeeding
ContraindicatedIt is not recommended to breast-feed the baby while taking the medicine as it may passes into breast milk.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel sleepy, dizzy, or tired while taking the medicine.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking the medicine.
Liver
Use with CautionBREVIPIL ORAL SOLUTION should be used with caution if you have liver problems.
Allergy
ContraindicatedDo not take BREVIPIL ORAL SOLUTION if you are allergic to Brivaracetam or any other ingredients of this medicine.
Use In Pediatrics
ContraindicatedBREVIPIL ORAL SOLUTION is not recommended for use in children under 2 years of age.
Use In Geriatrics
Use with CautionBREVIPIL ORAL SOLUTION should be used with caution in elderly patients (aged 65 years and above).
Others
Before taking BREVIPIL ORAL SOLUTION, inform your doctor if you have:
- depression, self-harming thoughts or any unusual changes in mood and behaviour
Interactions
A. Drug-Drug interactions:
Before taking BREVIPIL ORAL SOLUTION, inform your doctor if you are taking any of the following medicines:
- Antibiotics (Ex. rifampicin)
- Antidepression (Ex. St John’s wort)
- Anticonvulsants (Ex. carbamazepine, phenytoin)
Overdosage:
If you or anyone else accidentally takes too much of BREVIPIL ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Brivaracetam |
| Pharmacological Category | : | Anti-epileptics |
| Therapeutic Indication | : | Epilepsy |
| Dosage Forms | : | Tablet, Injection, Oral solution, syrup |
FAQs About BREVIPIL ORAL SOLUTION
Q: Can BREVIPIL ORAL SOLUTION be given to children at 2 years?
A: It is used in children from 2 years of age. This medicine is not recommended for children below 2 years of age.
Q: How to take BREVIPIL ORAL SOLUTION?
A: Take BREVIPIL ORAL SOLUTION as advised by your physician. Shake well before use. It can be taken as such or can be diluted with water before taking. It can be taken with or without food.
Q: What are the precautions to be taken if BREVIPIL ORAL SOLUTION is taken in excess?
A: If you or anyone else accidentally take too much of BREVIPIL ORAL SOLUTION, consult your doctor immediately or visit the nearby hospital.
Q: How do BREVIPIL ORAL SOLUTION act?
A: Brivaracetam works by attaching itself to specific sites (SV2A) on the surfaces of nerve cells which suppresses the abnormal activity of the nerve cells in the brain and manages the spread of electrical signals that cause seizures.
Q: Will BREVIPIL ORAL SOLUTION affect my ability to drive or use the machine?
A: Do not drive or operate machinery until you know how BREVIPIL ORAL SOLUTION affects you. BREVIPIL ORAL SOLUTION may cause drowsiness, tiredness, dizziness, and problems with your balance and coordination.
Q: Who should not take BREVIPIL ORAL SOLUTION?
A: Do not take BREVIPIL ORAL SOLUTION if you are allergic to brivaracetam or any other ingredients of this medicine.
Q: What are the most common side effects of BREVIPIL ORAL SOLUTION?
A: The most common side effects of taking BREVIPIL ORAL SOLUTION are feeling sleepy or dizzy, flu, feeling very tired, convulsion (a feeling of spinning), feeling and being sick and constipation, depression, anxiety, not being able to sleep, irritability, infection of nose and throat and decreased appetite or restlessness and hyperactivity (in children). Contact your doctor if any of the symptoms worsen.
References
1. Misty D. Smith, Cameron S. Metcalf, and Karen S. Wilcox. Pharmacotherapy of the Epilepsies. Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 13th Edition. New York McGraw Hill Medical 2018 Page – 303-326.
2. Felix Zahnert, Kristina Krause, Ilka Immisch, Lena Habermehl, Iris Gorny, Izabella Chmielewska, Leona Möller, Anna M. Weyand, Peter M. Mross, Jan Wagner, Katja Menzler and Susanne Knake. Brivaracetam in the Treatment of Patients with Epilepsy - First Clinical Experiences. Journal of Frontiers in neurology. February 2018. [Accessed on 2nd May 2022] click here
3. Farbod Khaleghi, and Eric C. Nemec. A Novel Adjunctive Therapy for Partial-Onset Seizures. February 2017. [Accessed on 2nd May 2022] click here
4. UCB Pharma limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on 2nd May 2022] click here
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