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Introduction About BIOSOL ORAL DROPS
BIOSOL ORAL DROPS contains Betamethasone, which belongs to the group of medicines called Corticosteroids. It is used to manage bronchial asthma, severe hypersensitivity reactions, anaphylaxis, autoimmune diseases (connective tissue disorders, rheumatoid arthritis, bullous pemphigoid, idiopathic thrombocytopenic purpura, etc.), inflammatory diseases of kidneys (minimal change nephrotic syndrome, acute interstitial nephritis), inflammatory diseases of intestine (ulcerative colitis, Crohn’s disease), sarcoidosis, rheumatic carditis, haemolytic anaemia (autoimmune), certain cancers, and immunosuppression in transplantation.
BIOSOL ORAL DROPS is not recommended to use in patients having infections in which management with antibiotics is not started and live virus immunization. Before taking BIOSOL ORAL DROPS, inform your doctor if you have liver, heart, or lung diseases, chickenpox or shingles, osteoporosis, high blood pressure, epilepsy, glaucoma (increased pressure within the eye), tuberculosis, peptic ulcers, or diabetes.
BIOSOL ORAL DROPS should be used with caution among women who are pregnant or breastfeeding. BIOSOL ORAL DROPS should be used with caution in children, adolescents, and elderly patients. Contact your doctor if feel any unusual symptoms while taking BIOSOL ORAL DROPS.
Uses Of BIOSOL ORAL DROPS
Manage:
- bronchial asthma
- severe hypersensitivity reactions, anaphylaxis
- autoimmune diseases (connective tissue disorders, rheumatoid arthritis, bullous pemphigoid, idiopathic thrombocytopenic purpura, etc.)
- inflammatory diseases of kidneys (minimal change nephrotic syndrome, acute interstitial nephritis)
- inflammatory diseases of intestine (ulcerative colitis, Crohn’s disease)
- sarcoidosis
- rheumatic carditis
- haemolytic anaemia (autoimmune)
- certain cancers (malignant lymphoma, multiple myeloma)
- immunosuppression in transplantation
How BIOSOL ORAL DROPS Works
BIOSOL ORAL DROPS inhibits certain chemical pathways in the body which reduces the formation of substances (arachidonic acid) that causes pain. It also enhances anti-inflammatory genes like interleukin 10. Therefore, helping in reducing pain and inflammation.
How to use BIOSOL ORAL DROPS
Take BIOSOL ORAL DROPS as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, weight, and health condition.
Side Effects Of BIOSOL ORAL DROPS
Rare
Stop taking BIOSOL ORAL DROPS and contact your physician immediately if you experience any of the following side effects:
- unusual symptoms or worsening of the existing condition
Warning & Precautions
Pregnancy
BIOSOL ORAL DROPS should be used with caution in pregnant women only if advised by the doctor as there is lack of data. Consult your doctor before taking BIOSOL ORAL DROPS.
Breastfeeding
BIOSOL ORAL DROPS should be used with caution in breastfeeding women under careful observation of the doctor as it passes through breast milk. Consult your doctor before taking it.
Liver
BIOSOL ORAL DROPS should be taken with caution in patients with liver diseases. Consult your doctor before taking BIOSOL ORAL DROPS.
Allergy
Do not take BIOSOL ORAL DROPS if you are allergic to Betamethasone or any of the other ingredients of this medicine.
Lungs
BIOSOL ORAL DROPS should be taken with caution in patients with lung diseases such as asthma. Consult your doctor before taking BIOSOL ORAL DROPS.
Heart Disease
BIOSOL ORAL DROPS should be used with caution in patients with heart diseases such as congestive heart failure. Consult your doctor taking BIOSOL ORAL DROPS.
Others
BIOSOL ORAL DROPS is not recommended for use if you have:
- infections in which management with antibiotics is not started
- undergone a live vaccine immunization
Before taking BIOSOL ORAL DROPS, inform your doctor if you have:
- stomach or duodenal ulcers
- tuberculosis (TB)
- epilepsy (fits)
- glaucoma (raised eye pressure)
- osteoporosis (thinning of the bones)
- chickenpox, shingles, or measles, or having contact with a person having these
- diabetes
- underactive thyroid gland
- myasthenia gravis
- steroid psychosis (confusion and agitation following high doses of corticosteroids)
- steroid myopathy (weakness of muscles of upper and lower limbs and neck)
- high blood pressure
Use in pediatrics:
BIOSOL ORAL DROPS should be used with caution in children and adolescents. Your doctor will decide the correct dose and duration of BIOSOL ORAL DROPS depending upon your child’s age, diseases condition and body weight. Consult your child’s doctor before taking BIOSOL ORAL DROPS.
Use in geriatrics:
BIOSOL ORAL DROPS should be used with caution in elderly patients as it may cause side effects serious consequences of the common side effects such as osteoporosis, hypertension, diabetes, susceptibility to infection and thinning of the skin. Consult your doctor before taking BIOSOL ORAL DROPS.
Interactions
A. Drug-Drug interactions:
Before taking BIOSOL ORAL DROPS, inform your doctor if you are taking any of the following medicine:
- medicines used for myasthenia gravis (Ex. pyridostigmine)
- medicines used to manage pain and inflammation such as non-steroidal anti-inflammatory drugs (Ex. ibuprofen), salicylates (Ex. aspirin)
- medicines used for thinning of the blood (Ex. warfarin)
- medicines used to manage tuberculosis (Ex. rifampicin, rifabutin)
- medicines used to manage epilepsy (Ex. carbamazepine, phenytoin)
- medicines used to manage HIV (Ex. ritonavir, cobicistat)
- medicines used as oral contraceptives (pills) (Ex. estradiol)
- medicines used to manage fungal infections (Ex. itraconazole)
- radiopaque dye used in Xray of gall bladder (Ex. cholecystography x-ray media)
- medicines used to manage hypotension (low blood pressure) (Ex. ephedrine)
Overdosage:
If you or anyone else accidentally take too much of BIOSOL ORAL DROPS, consult your doctor immediately or visit the nearby hospital. In cases of chronic overdosage, symptoms of hypercortisolism (extra cortisol in body) may occur such as thinning of skin, easy bruising, weight gain, and rounding of face.
Synopsis
| Drug | : |
Betamethasone |
| Pharmacological Category | : |
Corticosteroids |
| Therapeutic Indication | : |
Inflammation-related diseases like |
| Dosage Forms | : |
Tablet, Gel, Cream, Ointment, Lotion, Oil, Oral drops, Eye/Ear drops, Injection |
More Information
- Keep BIOSOL ORAL DROPS out of reach of children
- Store BIOSOL ORAL DROPS at a temperature, not more than 30°C
FAQs About BIOSOL ORAL DROPS
What if I forget to take a dose of BIOSOL ORAL DROPS?
If you forget a dose of BIOSOL ORAL DROPS, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed dose as this may increase the chances of developing side effects.
Is it safe to use BIOSOL ORAL DROPS in pregnancy and breastfeeding?
BIOSOL ORAL DROPS should be used with caution among women who are pregnant or breastfeeding. Consult your doctor before taking BIOSOL ORAL DROPS.
When BIOSOL ORAL DROPS is not recommended?
BIOSOL ORAL DROPS is not recommended to use in patients having infections in which management with antibiotics is not started. Consult your doctor before taking BIOSOL ORAL DROPS.
Is it safe to use BIOSOL ORAL DROPS in patients having diabetes?
BIOSOL ORAL DROPS is a corticosteroid which has tendency to inhibit glucose utilization and reduce glucose uptake which may worsen the condition of diabetes. Consult your doctor before using it.
Can I stop taking BIOSOL ORAL DROPS on my own?
It is very important to keep taking BIOSOL ORAL DROPS till the time your doctor has prescribed it to you. Do not stop taking it on your own even if you feel better as corticosteroids must be stopped gradually. Ask for your doctor’s advise if you wish to discontinue the use of BIOSOL ORAL DROPS due to any reason.
What precautions shall I take while on management with BIOSOL ORAL DROPS?
While getting managed with BIOSOL ORAL DROPS, keep away from patients having chicken pox or shingles and even tell your doctor beforehand if you yourself had them. Contact your doctor if you feel you got in touch with someone having these as taking BIOSOL ORAL DROPS may worsen the condition.
Is BIOSOL ORAL DROPS a steroid?
Yes. BIOSOL ORAL DROPS is potent steroid which inhibits certain chemical pathways in the body which reduces the formation of substances (arachidonic acid) that causes pain. It also enhances anti-inflammatory genes like interleukin 10. Therefore, helping in reducing pain and inflammation.
References
1. KD Tripathi. Corticosteroids. Drugs Essentials of medical pharmacology. Seventh edition. 2013. Page – 289.
2. Komal Gaur and Barna Ganguly. Effect of Single Dose Betamethasone Administration in Pregnancy on Maternal and Newborn Parameters. Journal of Clinical and Diagnostic Research. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2017 [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483699/
3. Peter T Daley-Yates, Alison C Price, Jonathan R Sisson, Adrian Pereira, and Nigel Dallow. Beclomethasone dipropionate: absolute bioavailability, pharmacokinetics and metabolism following intravenous, oral, intranasal and inhaled administration in man. NIH National Library of Medicine, National center for biotechnology information. Pubmed Central. May 2001 [Accessed on 18th August 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2014471/
4. Betamethasone. NIH National Library of Medicine, National center for biotechnology information. Pubchem. [Revised in August 2022] [Accessed on 18th August 2022] https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone
5. GlaxoSmithKline Pharmaceuticals Limited. Betnesol oral drops [Revised in January 2022] [Accessed on 19th August 2022] https://india-pharma.gsk.com/media/6344/betnesol-oral-drops.pdf
Useful Diagnostic Tests
- Absolute Eosinophil Count
- Peripheral Smear Examination
- Total IgE
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