Doctor Wonder (P) Limited

BIOMIXZAP Ear Drops 5ml

Ear Conditions
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    Introduction About BIOMIXZAP EAR DROPS

    What are BIOMIXZAP Ear Drops used for?

    BIOMIXZAP Ear Drops is an otic liquid formulated to support daily ear care. It is used for softening excess earwax, aiding in ear cleansing, and maintaining comfort in the ear canal. It is designed for regular use and also helps individuals manage ear hygiene with ease and convenience.

    Before using BIOMIXZAP Ear Drops, inform your doctor if you have any liver problems, kidney problems, mental illnesses, epilepsy or any systemic infections as a precaution. Consult your doctor before using BIOMIXZAP Ear Drops if you are pregnant or breastfeeding women.

    Always follow the directions provided by your healthcare provider or as mentioned on the product label. Gently tilt your head, apply the recommended number of drops, and allow the liquid to settle before returning to an upright position.

    If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice. If you wear soft contact lenses, remove the lens before applying BIOMIXZAP Ear Drops and wait for at least 15 minutes before reinsertion.

    BIOMIXZAP Ear Drops is suitable for individuals looking for regular ear hygiene solutions or those managing mild ear discomfort related to wax build-up. Consult a healthcare expert if unsure about usage suitability.

    BIOMIXZAP Ear Drops is generally safe and well-tolerated. It may cause very mild ear irritation or burning sensation following application which settles in few minutes. Keep in a cool, dry place away from direct sunlight. Store out of reach of children. Close the cap tightly after use.

    Uses Of BIOMIXZAP EAR DROPS

    It is used to:

    • manage ear bacteria and fungus infection
    • manage and reduce redness, swelling and itching of the ear
    • decrease the pain sensation
    • manage infection by works against the microorganisms that cause infection

    Benefits of BIOMIXZAP EAR DROPS

    • Contains a blend of ingredients to support earwax softening
    • Helpful in maintaining routine ear hygiene
    • Convenient dropper design for accurate application
    • Pack size: 5ml – ideal for individual use or travel

    How BIOMIXZAP EAR DROPS Works

    Understanding the Action of BIOMIXZAP on Earwax

    • Earwax (cerumen) is a naturally occurring substance that helps protect the ear canal by trapping dust, microorganisms, and foreign particles
    • However, when earwax accumulates excessively or becomes dry and impacted, it can lead to discomfort, reduced hearing clarity, or a feeling of fullness in the ear. This is where BIOMIXZAP Ear Drops 5ml plays a supportive role in maintaining ear canal balance
    • BIOMIXZAP Ear Drops are formulated with ingredients that help soften and break down hardened earwax, making it easier for the wax to exit the ear canal naturally
    • By helping to liquefy compacted wax, the drops assist in reducing ear congestion and improving overall ear cleanliness. This mechanism offers a gentler, non-invasive approach to managing earwax buildup, especially when used as part of a regular hygiene routine

    BIOMIXZAP Ear Drops 5ml contain a powerful combination of three active ingredients such as Neomycin Sulphate, Beclomethasone and Clotrimazole.,

    1. Neomycin Sulphate - 0.5%

    Neomycin is an aminoglycoside antibacterial agent which works by interfering with bacterial protein synthesis, thereby helping to reduce bacterial growth in the external ear canal. This ingredient supports ear hygiene by controlling the presence of common ear canal bacteria that may cause irritation or imbalance

    2. Beclomethasone Dipropionate - 0.025%

    • Beclomethasone is a corticosteroid known for its anti-inflammatory properties
    • It helps reduce swelling, redness, and discomfort in the ear canal that may arise from wax impaction or external irritation. Its presence helps maintain comfort while other ingredients work on softening and clearing wax or debris

    3. Clotrimazole - 1.0%

    • Clotrimazole is an antifungal agent that supports the control of fungal overgrowth in the ear canal, especially in humid or moist conditions
    • It helps maintain a balanced microbial environment, which is essential for individuals with recurring ear canal sensitivity or exposure to water and sweat

    How long does it take for BIOMIXZAP to work?

    The time it takes for BIOMIXZAP Ear Drops 5ml to support ear canal comfort and wax softening may vary depending on the amount and consistency of earwax, as well as individual ear conditions.

    • Initial Softening: Many users may begin to notice a softening effect within 1 to 3 days of regular use
    • Wax loosening and removal: For more compacted earwax, it may take up to 5 to 7 days of consistent application to support natural wax loosening and easier drainage
    • It is important to apply the drops exactly as directed, usually once or twice daily, and allow them to remain in the ear canal for the suggested duration (often 5–10 minutes per use) to maximize effectiveness

    How to use BIOMIXZAP EAR DROPS

    • Always follow the directions provided by your healthcare provider or as mentioned on the product label
    • Gently tilt your head, apply the recommended number of drops, and allow the liquid to settle before returning to an upright position

    Step-by-Step guide to applying ear drops

    Step 1: Before handling the ear drops, thoroughly wash your hands with soap and water to prevent introducing any germs into the ear canal

    Step 2:  If the drops feel too cold, gently warm the bottle by holding it in your hand for 1–2 minutes. This can make the application more comfortable and reduce the sensation of dizziness during use

    Step 3: Shake the Bottle. Check the product label or leaflet to see if shaking is necessary. Some formulations may need gentle mixing before use

    Step 4: Tilt your head to the side or lie down with the affected ear facing up. This position allows the drops to reach deeper into the ear canal

    Step 5: Using the dropper, gently place the recommended number of drops into the ear canal. Avoid touching the dropper tip to the ear or any other surface to keep it sterile

    Step 6: Stay in the same position for 5–10 minutes to allow the drops to penetrate and act effectively. You may gently pull the earlobe to help the drops move deeper inside

    Step 7: Use a clean tissue to wipe away any drops that may spill out. Do not insert cotton or any object into the ear canal

    Step 8: If both ears are affected, repeat the same process for the other ear, ensuring you follow hygiene precautions again

    Recommended dosage and frequency:

    The typical recommended dosage for BIOMIXZAP Ear Drops 5ml is:

    • 2 to 3 drops in the affected ear
    • Frequency: Twice daily or as advised by a registered medical practitioner
    • Duration: Follow the full course recommended, even if symptoms appear to improve earlier
    • Dosage may vary based on individual ear conditions, age, and healthcare recommendations

    Tips for Safe and Effective Application

    • Warm the bottle in your hands before use for comfort
    • Lie down or tilt your head sideways while instilling drops
    • Pull the earlobe gently to allow deeper penetration into the canal
    • Remain in position for 5–10 minutes after application
    • Clean the dropper tip with a dry tissue after use and replace the cap tightly
    • Wash hands before and after applying the drops

    Things to avoid during use

    • Do not insert cotton swabs or earbuds into the ear canal
    • Avoid touching the dropper tip to any surface to prevent contamination
    • Do not use on broken or perforated eardrums without medical supervision
    • Avoid sharing the ear drops with others, even for similar symptoms
    • Do not skip or double the dose unless advised by a healthcare provider
    • Avoid contact with eyes or mucous membranes

    Overdose

    If you or anyone else accidentally used excessive amount of BIOMIXZAP EAR DROPS, rinse your ears with warm water. If you or anyone else accidentally swallowed this medicine, consult your doctor immediately.

    Side Effects Of BIOMIXZAP EAR DROPS

    Possible Reactions to Look Out For

    BIOMIXZAP EAR DROPS is generally safe and well-tolerated. It may cause very mild ear irritation or burning sensation following application which settles in few minutes.

    When Should You Seek Medical Advice

    • persistent ear discomfort 
    • fluid discharge, bleeding, or unusual ear drainage
    • dizziness or balance issues following application
    • Itching, redness, or swelling around the ear
    • hearing changes such as muffled sounds or reduced hearing
    • burning or severe irritation after instilling the drops
    • signs of allergic reaction, like rash or facial swelling

    Warning & Precautions

    Pregnancy

    Use with Caution

    BIOMIXZAP Ear Drops should be used with caution in pregnant women.

    Breastfeeding

    Use with Caution

    BIOMIXZAP Ear Drops should be used with caution in breastfeeding women.

    Driving and Using Machines

    Use with Caution

    Do not drive or handle any heavy machinery if your ability is affected by BIOMIXZAP Ear Drops.

    Kidney

    Use with Caution

    BIOMIXZAP Ear Drops should be used with caution in patients with kidney problems.

    Liver

    Use with Caution

    BIOMIXZAP Ear Drops should be used with caution in patients with liver problems.

    Allergy

    Contraindicated

    Do not use BIOMIXZAP Ear Drops if you are allergic to Beclomethasone, Clotrimazole, Neomycin or any other ingredients of this medicine.

    Use In Pediatrics

    Contraindicated

    BIOMIXZAP Ear Drops is not recommended for use in children and adolescents (aged below 18 years).

    Use In Geriatrics

    Consult your doctor

    The safety and effectiveness of BIOMIXZAP Ear Drops have not been established in geriatric patients.

    Who should not take [GBNKEYWORD

    BIOMIXZAP Ear Drops is not recommended for use in patients with:

    • epilepsy
    • psychiatric illnesses
    • severe systemic infections

    Diet and Lifestyle Advice

    How do I clean my ears safely at home?

    1. Use Ear Drops (Like BIOMIXZAP Ear Drops 5ml)

    • Soften hardened earwax with ear drops containing ingredients like Neomycin, Clotrimazole, or Beclomethasone, as advised by a healthcare provider
    • Follow instructions carefully for proper dosage and frequency

    2. Warm Water Rinse

    • After softening wax with ear drops, you can gently rinse the ear with warm water using a soft bulb syringe (only if recommended by a doctor)
    • Tilt your head to let the water and wax drain out

    3. Wipe the Outer Ear

    • Use a clean, damp cloth to gently wipe around the outer ear
    • Avoid inserting cloth, cotton swabs, or any sharp objects into the ear canal

    Learn how to build a safe ear hygiene routine

    1. Understand that ears self-clean

    The ears naturally move wax and debris out of the canal. Avoid trying to clean deep inside the ear, as this can damage the eardrum or push wax further in

    2. Clean only the outer ear

    Use a clean, damp washcloth or cotton pad to wipe around the outer ear (auricle). This removes sweat, dirt, and residual wax without disturbing the inner ear canal

    3. Use wax-softening drops when needed

    Use drops like BIOMIXZAP Ear Drops 5ml if you notice dry, hardened wax. feeling of fullness or blocked ears, discomfort due to wax buildup

    4. Keep ears dry after bathing

    Trapped moisture can cause discomfort or ear canal imbalance. Dry your ears gently after showering or swimming using a towel and tilt your head to let water drain naturally

    5. Avoid inserting objects into the ear

    Do not use cotton swabs, bobby pins, or earbuds, sharp objects or DIY tools. These can cause micro-injuries or push wax deeper into the canal

    6. Check for symptoms that need care

    If you notice persistent itching, muffled hearing, discharge, ear discomfort

    Include practical tips like ear hygiene routines compatible with daily headphone users

    Wearing headphones or earphones for long hours can create a warm, enclosed environment inside the ears, often leading to moisture imbalance, wax buildup, and occasional discomfort. Pairing your daily tech habits with an ear-friendly hygiene routine supported by products like BIOMIXZAP Ear Drops 5ml can help maintain ear canal comfort and cleanliness

    • Include a weekly ear care routine
    • Take headphone breaks: Follow the 60/60 rule, use headphones at no more than 60% volume for no longer than 60 minutes at a time
    • Keep your headphones clean
    • Monitor for early discomfort signs

    How to keep your ears comfortable with daily headphone use: The role of BIOMIXZAP Ear Drops

    Why headphone users experience ear discomfort?

    • Trap heat and moisture in the ear canal
    • Disrupt natural wax migration
    • Cause a feeling of fullness or mild irritation
    • Contribute to excess wax build-up due to restricted airflow

    How BIOMIXZAP Ear Drops can help

    • Neomycin Sulphate – Helps support a clean environment in the ear canal
    • Beclomethasone Dipropionate – Supports relief from minor canal irritation
    • Clotrimazole – Helps rebalance ear hygiene when moisture is trapped

    Simple tips to support ear comfort

    • Use BIOMIXZAP drops once or twice weekly (or as advised by a healthcare provider)
    • Take regular headphone breaks to allow your ears to air out
    • Wipe down your headphones to avoid introducing dust or residue
    • Keep ears dry after workouts, showers, or extended listening sessions
    • Avoid inserting cotton swabs or ear-cleaning tools, which may push wax deeper

    Drug - Drug interaction

    • Avoid using multiple topical ear medications simultaneously unless instructed by a healthcare provider, as combining products may affect the way each one works
    • If you are using systemic corticosteroids, antibiotics, or antifungal medicines, always let your doctor know before adding BIOMIXZAP to your routine
    • Consult before using with hearing aids or ear devices, as residual drops may interact with device hygiene or cause buildup

    Synopsis

    Drug :   Beclomethasone, Clotrimazole, Neomycin
    Pharmacological Category :   Corticosteroids, Azole Antifungals, Aminoglycosides
    Therapeutic Indication :   Ear infections, pain and inflammation         
    Dosage Forms :   Drops, Ear drops

    More Information

    Alternatives to BIOMIXZAP Ear Drops: Suggests other products for comparison

    Product

    Key Ingredients

    Use-Case Suitability

    BIOMIXZAP

    Neomycin, Beclomethasone, Clotrimazole

    Wax softening + moisture balance + hygiene support

    SoluEar

    Surfactant-based agents

    Softening hard/dry wax

    Waxolve

    Oil-based wax solvents

    Routine use for dry ears prone to wax accumulation

    Otosol

    Antiseptic + soothing ingredients

    Mild itching and general irritation relief

    Ciplox D

    Ciprofloxacin + Dexamethasone

    Physician-directed use for inflammation/discomfort

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    • Audiovit-Z Capsule 10’s

    Why choose BIOMIXZAP Ear Drops?

    With its precision formulation and ease of application, BIOMIXZAP Ear Drops supports everyday ear care without complications. It is a go-to option for those who prioritize clean, healthy ears.

    FAQs About BIOMIXZAP EAR DROPS

    Q: What is BIOMIXZAP Ear drops used for?

    A: BIOMIXZAP Ear drops is used in the management of ear infections, pain, inflammation, itching, swelling and discomfort.

    Q: Can BIOMIXZAP cause ear irritation or allergy?

    A: Yes, BIOMIXZAP Ear Drops 5ml may cause ear irritation or allergic reactions in certain individuals, though such responses are not common.

    Q: How many drops of BIOMIXZAP should I use daily?

    A: For BIOMIXZAP Ear Drops 5ml, the recommended dosage is to gently instill a few drops into the affected ear 2 to 3 times a day. This application should be done as advised by your physician.

    Q: Can BIOMIXZAP help with earwax buildup or discomfort?

    A: BIOMIXZAP may assist in managing mild earwax-related discomfort through gentle softening and moisture support but is not a substitute for professional ear care when needed.

    Q: Should I avoid BIOMIXZAP if I have an ear infection?

    A: If you suspect an ear infection, it is important to consult a healthcare professional before using BIOMIXZAP Ear Drops 5ml.

    Q: How BIOMIXZAP EAR DROPS works?

    A: BIOMIXZAP EAR DROPS temporarily stops pain sensations, blocks the production of certain chemicals that causes inflammation and swelling and stops the activity of microbes (fungi and bacteria).

    Q: How fast BIOMIXZAP EAR DROPS acts?

    A: It takes around 30 seconds to 1 minute for BIOMIXZAP Ear drops to stop pain sensation. However, this time period may vary from person to person based on severity of pain and infection.

    Q: When will I see an improvement in my condition after using BIOMIXZAP EAR DROPS?

    A: BIOMIXZAP EAR DROPS may take around 7 days for you to notice an improvement in your condition. However, this time period may vary from person to person based on severity of pain and infection.

    Q: Who should not use BIOMIXZAP Ear drops?

    A: Before using BIOMIXZAP Ear drops, inform your doctor if you have liver problems, kidney problems, mental illnesses, epilepsy or any systemic infections as a precaution. Do not use BIOMIXZAP Ear drops, if you are allergic to any of its ingredients.

    Q: How to apply BIOMIXZAP Ear drops?

    A: Use BIOMIXZAP Ear drops as advised by your physician. It is for topical use only. Gently instill few drops of this medicine into the affected ears, 2-3 times a day. Wash your hands before and after application. Do not touch the tip of the container with your fingers, to avoid contamination. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice.

    Q: What precautions must be followed while using BIOMIXZAP Ear drops?

    A: Use BIOMIXZAP Ear drops exactly as instructed by your physician. Misuse or overuse of this medicine may lead to unwanted side effects. If there is no improvement in your condition even after using this medicine for 7 days, consult your doctor for advice. If you wear soft contact lenses, remove the lens before applying BIOMIXZAP Ear drops and wait for at least 15 minutes before reinsertion. Before using BIOMIXZAP Ear drops inform your doctor if you have any liver problems, kidney problems, mental illnesses, epilepsy or any systemic infections as a precaution.

    Q: Is BIOMIXZAP Ear drops safe?

    A: BIOMIXZAP Ear drops is generally safe and well-tolerated. It may cause very mild ear irritation or burning sensation following application which vanishes in few minutes.

    Q: Can BIOMIXZAP Ear drops be used in children?

    A: BIOMIXZAP Ear drops is not recommended for use in children and adolescents (aged below 18 years).

    Q: What if I miss a dose of BIOMIXZAP Ear drops?

    A: If you missed a dose of BIOMIXZAP Ear drops, apply it as soon as you remember. However, if it is time for next dose, skip the missed dose and use the regular dose. Do not use a double dose to compensate the missed dose.

    Q: Can I stop using BIOMIXZAP Ear drops once my symptoms subside?

    A: No. Do not stop using BIOMIXZAP Ear drops without consulting your doctor as it may make your symptoms to re-appear. Therefore, use this medicine consistently for the duration instructed by your doctor to achieve better results.

    References

    1. KD. Tripathi. Essential of Medical Pharmacology. 7th Edition. Drugs acting on peripheral nervous system. Antifungal agents. Aminoglycoside Antibiotics. Drugs Acting on Skin and Mucous Membrane. Page – 366, 743, 750, 787, 792, & 895.

    2. Efficacy and Safety for the Combination of Neomycin, Beclomethasone, Clotrimazole and Lignocaine for the Treatment of Otitis Media with Perforation and Otitis Externa: Post-Marketing Surveillance Study. International Journal of Medical Science and clinical inventions. July 2021. [Accessed on 30th May 2025]  

    3. Otiflox Ear Drops. Centuar Pharma. [Revised in January 2021] [Accessed on 30th May 2025]  

    4. Doctor wonder private Limited. [Accessed on 30th May 2025]  

    Useful Diagnostic Tests

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Purvi Raghuvanshi - MBBS, ENT
    Last updated on 31 May 2025 | 06:46 PM(IST)
    Lab updated