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Macleods Pharmaceuticals Pvt Ltd

BIO D3 Fem Capsule 10'S

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    Introduction About BIO D3 FEM CAPSULE

    BIO D3 FEM CAPSULE is a combination of Calcitriol, Calcium Carbonate, Magnesium Oxide, Menaquinone, and Soy Isoflavones, which belong to the group of medicines called Vitamins, Minerals, and Nutrients, respectively. It is used to manage post-menopausal osteoporosis and to reduce the risk of osteoporosis in women.

    Menopause is the time that marks the natural end of reproductive age for a woman, along with the cessation of the menstrual cycle and a decline in reproductive hormone levels in the body. It is characterized by symptoms such as bone loss (postmenopausal osteoporosis), irregularity in periods, vaginal dryness, hot flashes, chills, night sweats, and sleep problems.

    Osteoporosis is a condition that causes the thinning and weakening of bones because of the excessive absorption of calcium from the bones. It is characterized by symptoms such as bleeding gums, weak grip strength, brittle fingernails, loss of height, frequent fractures, and neck and back pain.

    BIO D3 FEM CAPSULE is not recommended for use if you have high levels of calcium in your blood, have metastatic calcification (extra deposits of calcium in your body), or are not well because of high levels of vitamin D in your body.

    BIO D3 FEM CAPSULE should be used with caution in patients with kidney disease or non-alcoholic fatty liver disease. BIO D3 FEM CAPSULE should be used with caution by pregnant and breastfeeding women. It should be used with caution in children (under 12 years of age) and elderly patients (aged 65 or older). Consult your doctor before taking it.

    The common side effects associated with the use of BIO D3 FEM CAPSULE are diarrhea, constipation, an upset stomach, and abdominal pain. Contact your doctor or a nearby hospital if any of the conditions worsen.

    Uses Of BIO D3 FEM CAPSULE

    • To manage post-menopausal osteoporosis

    How BIO D3 FEM CAPSULE Works

    BIO D3 FEM CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body.

    Magnesium oxide reduces the activity of bone-resorbing cells and improves the activity of bone-depositing cells. Vitamin K activates the calcium-binding actions of two proteins (the matrix GLA protein and osteocalcin), which helps in enhancing calcium absorption in the body, thereby increasing mass and strength. Soy isoflavones mimic the actions of estrogen, which is a hormone needed for calcium deposition in the bones, thereby reversing bone loss.

    How to use BIO D3 FEM CAPSULE

    Take BIO D3 FEM CAPSULE as advised by your physician. Swallow the medicine with a glass of water with food. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

    Side Effects Of BIO D3 FEM CAPSULE

    Common

    • diarrhoea
    • constipation
    • upset stomach
    • abdominal pain

    Rare

    • signs of changes in kidney function, such as nausea, vomiting, and abdominal pain
    • signs of an increase in blood calcium levels, such as loss of appetite, weight loss, nausea, vomiting, headache, sluggishness, drowsiness, and weakness
    • signs of very high levels of blood calcium levels, such as high fever, feeling thirsty, dehydration, passing more water than normal, wetting the bed, constipation, stomach pain, blockage of the bowel, an uneven heartbeat, infections in the bladder, and stoppage of normal growth

    Stop taking BIO D3 FEM CAPSULE and contact your doctor if you experience any of the following side effects:

    • signs of severe allergic reactions such as itchy skin, skin rashes, and reddening of the skin
    • itchy welts
    • dizziness or light-headedness
    • mood or mental changes
    • unusual tiredness
    • weakness
    • nausea, and vomiting

    How To Manage Side Effects

    Constipation

    Try to eat more high-fiber foods, such as fresh fruit, vegetables, and cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor about receiving alternate managements for constipation.

    Indigestion

    Avoid taking tea, coffee, cola, or alcohol. If you are overweight, try to lose weight. Try doing regular exercises. Stay hydrated and avoid fasting.

    Nausea And Vomiting

    Try to take BIO D3 FEM CAPSULE with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom gets worse.

    Warning & Precautions

    Pregnancy

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution if you are pregnant, think you are pregnant, or plan to get pregnant. Consult and inform your doctor before taking it.

    Breastfeeding

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in breastfeeding women as it passes through the milk. Consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    BIO D3 FEM CAPSULE is not likely to affect your being able to drive or use any tools or machines.

    Kidney

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in patients with kidney problems, such as chronic kidney disease. Consult your doctor for advice before taking it.

    Liver

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in patients with non-alcoholic fatty liver disease. Consult your doctor before taking it.

    Allergy

    Contraindicated

    BIO D3 FEM CAPSULE is not recommended for use if you are allergic to calcitriol, calcium carbonate, magnesium oxide, menaquinone, soy isoflavones, or any of the other ingredients of this medicine. Consult your doctor before taking it.

    Heart Disease

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in patients with heart problems such as chronic kidney disease. Consult your doctor for advice before taking it.

    Use In Pediatrics

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in children (below 4 years). Consult your doctor before taking it.

    Use In Geriatrics

    Use with Caution

    BIO D3 FEM CAPSULE should be used with caution in elderly patients (above 70 years). Consult your doctor before taking it.

    Others

    BIO D3 FEM CAPSULE is not recommended for use if you:

    • have high blood calcium levels
    • have metastatic calcification (extra deposits of calcium in your body)
    • are not well because of high levels of vitamin D in your body

    Before taking BIO D3 FEM CAPSULE, inform your doctor if you:

    • are immobilized due to an operation or any other reason
    • have an intestinal disease
    • have high blood pressure
    • are on low-salt, low-sugar, or another special diet

    Interactions

    A. Drug-Drug Interactions:

    Before taking BIO D3 FEM CAPSULE, inform your doctor if you are taking any of the following medicines:

    • other medicines containing vitamin D
    • diuretics or water tablets (medicines used to manage high blood pressure) Ex. bendroflumethiazide, chlortalidone, indapamide.
    • digoxin or digitoxin (a medicine used to manage heart diseases)
    • medicines containing magnesium, such as antacids (medicines used to manage indigestion) Ex. magnesium hydroxide
    • laxatives (medicines used to manage constipation) Ex. bisacodyl
    • corticosteroids (medicines used to manage pain and inflammation) Ex. hydrocortisone, prednisolone, and dexamethasone
    • medicines used to manage high levels of blood cholesterol, such as ion-exchange resins Ex. cholestyramine
    • phosphate (a medicine used to manage certain urinary tract infections)
    • anticoagulants (medicines used to delay blood clotting time) Ex. warfarin, aspirin
    • medicines used to manage ulcers Ex. cimetidine, ranitidine

    B. Drug-Food Interactions:

    Avoid eating food that is rich in vitamin D (dairy products like milk and cheese) or has added vitamin D while taking BIO D3 FEM CAPSULE. Consult your doctor before taking it.

    Overdosage:

    If you or anyone else accidentally takes too much of BIO D3 FEM CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are loss of appetite, weight loss, nausea, vomiting, constipation, headache, sluggishness, drowsiness, weakness, loss of consciousness, difficulty breathing, seizure, or collapse.

    Synopsis

    Drug :   Calcitriol, Calcium Carbonate, Magnesium Oxide, Menaquinone, Soy Isoflavones
    Pharmacological Category :   Vitamins, minerals, and nutrients
    Therapeutic Indication :   Post-menopausal osteoporosis and reduce the risk of osteoporosis        
    Dosage Forms :   Capsule, softgel capsule

    More Information

    • Keep the medicine out of the reach of children
    • Store BIO D3 FEM CAPSULE at room temperature

    FAQs About BIO D3 FEM CAPSULE

    Q: What is BIO D3 FEM CAPSULE used for?

    A: BIO D3 FEM CAPSULE is used to manage post-menopausal osteoporosis and reduce the risk of osteoporosis in women. Osteoporosis is a condition that causes the thinning and weakening of bones because of the excessive absorption of calcium from the bones. Consult your doctor before taking BIO D3 FEM CAPSULE.

    Q: What happens if you take more BIO D3 FEM CAPSULE than your required dose?

    A: If you or anyone else accidentally takes too much BIO D3 FEM CAPSULE, consult your doctor immediately or visit the nearby hospital. Symptoms of overdosage are loss of appetite, weight loss, nausea, vomiting, constipation, headache, sluggishness, drowsiness, weakness, loss of consciousness, difficulty breathing, seizure, or collapse.

    Q: What side effects are seen with BIO D3 FEM CAPSULE?

    A: The common side effects associated with the use of BIO D3 FEM CAPSULE are constipation, indigestion, nausea, and vomiting. Contact your doctor or a nearby hospital if any of the conditions worsen.

    Q: Who should avoid taking BIO D3 FEM CAPSULE?

    A: BIO D3 FEM CAPSULE is not recommended for use if you are allergic to calcitriol, calcium carbonate, magnesium oxide, or any other metabolite of vitamin D such as alfacalcidol and cholecalciferol. It is also not recommended for use if you have high levels of calcium in your blood, have metastatic calcification (extra deposits of calcium in your body), or are not well because of high levels of vitamin D in your body. Consult your doctor before taking BIO D3 FEM CAPSULE.

    Q: Is BIO D3 FEM CAPSULE safe to use in children or elderly patients?

    A: BIO D3 FEM CAPSULE should be used with caution in children (aged below 12 years) and elderly patients (aged above 70 years). Consult your doctor before taking BIO D3 FEM CAPSULE.

    Q: How does BIO D3 FEM CAPSULE work?

    A: BIO D3 FEM CAPSULE helps in managing bone weakening, where calcitriol plays a very important role in aiding the absorption of calcium by acting on certain gut cells to increase the production of calcium transport proteins, whereas calcium carbonate acts by directly increasing the calcium stores in the body. Magnesium oxide reduces the activity of bone-resorbing cells and improves the activity of bone-depositing cells. Vitamin K activates the calcium-binding actions of two proteins (the matrix GLA protein and osteocalcin), which helps in enhancing calcium absorption in the body, thereby increasing bone mass and strength. Soy isoflavones mimic the actions of estrogen, which is a hormone needed for calcium deposition in the bones, thereby reversing bone loss.

    Q: Is BIO D3 FEM CAPSULE safe for use by pregnant and breastfeeding women?

    A: BIO D3 FEM CAPSULE should be used with caution if you are pregnant, think you are pregnant, or plan to get pregnant. It should also be used with caution by breastfeeding women. Consult your doctor before taking BIO D3 FEM CAPSULE.

    Q: Is BIO D3 FEM CAPSULE safe to use in liver patients?

    A: BIO D3 FEM CAPSULE should be used with caution in patients with non-alcoholic fatty liver disease (abnormally increased lipid levels in liver tissues unrelated to alcoholism). Consult your doctor before taking BIO D3 FEM CAPSULE.

    Q: Is BIO D3 FEM CAPSULE safe to use in kidney patients?

    A: BIO D3 FEM CAPSULE should be used with caution in patients with kidney diseases (diseases involving the kidneys resulting in impaired removal of toxins from the body). Consult your doctor for advice before taking BIO D3 FEM CAPSULE.

    Q: What if I forget to take my BIO D3 FEM CAPSULE dose?

    A: If you forgot to take your BIO D3 FEM CAPSULE dose, take it as early as possible. Do not double up the dose to make up for the forgotten one. Consult your doctor before taking BIO D3 FEM CAPSULE.

    References

    1. KD Tripathi. Drugs Affecting Calcium Balance. Essentials of Medical Pharmacology. Seventh Edition. 2013. Page-341.

    2. Mitra Hariri, Sara Zohdi. Effect of Vitamin D on Non-Alcoholic Fatty Liver Disease: A Systematic Review of Randomized Controlled Clinical Trials. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. January 2019. [Assessed on 12th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360993/

    3. Meghan Meehan, Sue Penckofer. The Role of Vitamin D in the Aging Adult. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. December 2014. [Assessed on 12th February 2024] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399494/

    4. Atnahs Pharma UK Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Assessed on 12th February 2024] https://www.medicines.org.uk/emc/files/pil.11802.pdf

    5. Dailymed. CALCIUM CARBONATE 500 MG. [Revised in October 2021] [Assessed on 12th February 2024] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=322f1b54-abe9-11a7-e054-00144ff8d46c

    6. MedlinePlus. Magnesium Oxide. [Revised in October 2015] [Assessed on 12th February 2024] https://medlineplus.gov/druginfo/meds/a601074.html

    7. Macleods Pharmaceuticals Ltd. BIO D3 FEM. [Assessed on 12th February 2024] https://www.macleodspharma.com/products/

    8. Leeford. GEOMAX D3 FEM. [Assessed on 12th February 2024] https://www.leeford.in/product/500/geomax-d3-fem

    Useful Diagnostic Tests

    • Calcium
    • Vitamin D 1,25 Dihydroxy
    • Extended Arthritis Care
    • Comprehensive Arthritis Care
    • Basic Bone Care
    • Advance Bone Care
    • Comprehensive Bone Care
    • Esr Automated
    • Basic Arthritis Care Plan
    • Bone Strength Package
    • Arthritis Profile-Basic
    • Arthritis Profile-Advanced
    • Kidney Function Test (KFT)
    • Serum Electrolytes/ Electrolytes Profile
    • Pth-Intact Molecule Parathyroid Hormone

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 13 Feb 2024 | 05:53 PM(IST)
    Lab updated