Bestomax IV Injection 1'S
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Introduction About BESTOMAX IV INJECTION
BESTOMAX IV INJECTION is used in the management of various bacterial infections such as respiratory tract infections (pneumonia, acute exacerbation of chronic bronchitis), urinary tract infections (cystitis, urethritis, pyelonephritis), bone and joint infections (osteomyelitis), middle ear infections (otitis media), tonsillitis, sinusitis, skin and soft tissue infections such as cellulitis, boils, wound infections, intra-abdominal sepsis, dental infections, and infections of genital organs in females.
BESTOMAX IV INJECTION is also used as prophylaxis against various bacterial infections associated with major surgeries of the heart, joints, kidney, head and neck, stomach, biliary tract, intestine, and pelvic region. Along with management with this medicine, your doctor might order bacterial culture tests to enhance the outcomes of the management.
It contains a combination of medicines called Amoxicillin and Clavulanic acid, which belong to the group of medicines called Penicillins and Beta-Lactamase Inhibitors. It works by preventing the growth of the bacteria and thus clearing up the infection.
BESTOMAX IV INJECTION is not recommended for use in patients with severe kidney impairment who had a history of liver problems or jaundice after taking penicillin antibiotics. It should be used with caution in patients suffering from glandular fever (a viral infection causing sore throat, high fever, swelling of salivary glands, etc.), liver disease, kidney disease, who are not passing urine daily, convulsions (fits), or large intestine inflammation.
BESTOMAX IV INJECTION is not recommended for use in pregnant women unless necessary. It should be used with caution in breastfeeding women, as it may pass through breast milk. BESTOMAX IV INJECTION should be used with caution in children as it may require dose modification.
The most common side effects after receiving BESTOMAX IV INJECTION are diarrhea, thrush (fungal infection), etc. Consult your doctor immediately if any of your symptoms get worse or persist.
Uses Of BESTOMAX IV INJECTION
- Management of various bacterial infections
How BESTOMAX IV INJECTION Works
BESTOMAX IV INJECTION helps in managing bacterial infection, where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall), leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell, clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases and hence enhances the antibacterial activity of amoxicillin.
How to use BESTOMAX IV INJECTION
- This medicine will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or intravenous injection.
- Your doctor will decide the exact dose and duration of management for you depending on your age, body weight, and disease condition.
Side Effects Of BESTOMAX IV INJECTION
Common Side Effects of BESTOMAX IV INJECTION:
- diarrhoea
- thrush (candida fungal infection)
Stop receiving BESTOMAX IV INJECTION and consult your doctor immediately in case you experience:
- severe allergic reaction, which includes rashes, collapsing or fainting, swelling of the face and throat, which may cause difficulty breathing, fever, joint pain, swollen lymph nodes of the neck, armpits, and groin, and red or purple raised spots on skin due to inflammation of blood vessels
- watery diarrhea with blood or mucus, fever, and abdominal pain that occurs due to inflammation of the large intestine
Warning & Precautions
Pregnancy
Monitoring requiredBESTOMAX IV INJECTION is not recommended for use in pregnant women unless necessary.
Breastfeeding
Use with CautionBESTOMAX IV INJECTION should be used with caution in breastfeeding women as it may pass through breast milk.
Driving and Using Machines
ContraindicatedDo not drive or operate machinery after receiving BESTOMAX IV INJECTION.
Kidney
Consult your doctorBESTOMAX IV INJECTION is not recommended for use in patients with severe kidney impairment. It should be used with caution in patients suffering from kidney problems.
Liver
Consult your doctorBESTOMAX IV INJECTION is not recommended for use in patients who had a history of liver problems or jaundice after taking penicillin antibiotics. It should be used with caution in patients suffering from liver disease.
Allergy
ContraindicatedDo not receive BESTOMAX IV INJECTION if you are allergic to amoxicillin, clavulanic acid, or any other ingredients in this medicine.
Use In Pediatrics
Use with CautionBESTOMAX IV INJECTION should be used with caution in children as it may require dose modification.
Use In Geriatrics
Use with CautionBESTOMAX IV INJECTION should be used with caution in the elderly.
Others
Before receiving BESTOMAX IV INJECTION, inform your doctor if you have:
- glandular fever (viral infection causing sore throat, high fever, swelling of salivary glands, etc.)
- not been urinating regularly
- convulsions (fits)
- large intestine inflammation
- urine and blood tests
Interactions
A. Drug-Drug interactions:
Before receiving BESTOMAX IV INJECTION, inform your doctor if you are taking any of the following medicine:
- medicines used to manage gout (Ex. allopurinol, probenecid)
- medicines used to manage blood clots (Ex. warfarin)
- methotrexate (used for the management of cancer, severe psoriasis)
- medicine used to manage organ transplant rejection (Ex. mycophenolate mofetil)
- medicines used for management of pregnancy (oral contraceptives)
Overdosage:
BESTOMAX IV INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, consult your doctor or nurse immediately if you experience any unusual symptoms. Symptoms of overdose of BESTOMAX IV INJECTION are nausea, diarrhea, fits, and an upset stomach.
Synopsis
| Drug | : | Amoxicillin, Clavulanic Acid |
| Pharmacological Category | : | Penicillins and Beta-Lactamase Inhibitors |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Tablet, Capsule, Sachet, Dry Syrup, Suspension, Syrup, Drops, Injections |
FAQs About BESTOMAX IV INJECTION
Q: What are the uses of BESTOMAX IV INJECTION?
A: BESTOMAX IV INJECTION is used in adults and children for the management of various bacterial infections such as respiratory tract infections, urinary tract infections, bone and joint infections, middle ear infections, tonsillitis, sinusitis, skin and soft tissue infections, intra-abdominal sepsis, dental infections, and infections of genital organs in females. It is also used as prophylaxis against various bacterial infections associated with major surgeries.
Q: What are the side effects of BESTOMAX IV INJECTION?
A: The most common side effects after receiving BESTOMAX IV INJECTION are vomiting, diarrhea, thrush (fungal infection), etc. Consult your doctor immediately in case any of the side effects worsen.
Q: How does BESTOMAX IV INJECTION work?
A: BESTOMAX IV INJECTION helps in managing bacterial infection, where Amoxicillin works by inhibiting penicillin-binding proteins (which are involved in the synthesis of the bacterial cell wall), leading to the activation of autolytic enzymes in the bacterial cell wall. Therefore, leading to lysis of the cell wall and death of the bacterial cell, clavulanic acid inhibits the activity of bacterial enzymes known as beta-lactamases, hence enhancing the antibacterial activity of amoxicillin.
Q: Is BESTOMAX IV INJECTION safe for use in pregnant and breastfeeding women?
A: No, BESTOMAX IV INJECTION is not recommended for use in pregnant women unless necessary, and BESTOMAX IV INJECTION should be used with caution in breastfeeding women as it may pass through breastmilk. Consult your doctor before receiving BESTOMAX IV INJECTION.
Q: How BESTOMAX IV INJECTION is given?
A: This medicine will be given to you only by a doctor or a nurse into a vein as an intravenous infusion or intravenous injection. Your doctor will decide the exact dose and duration of management for you depending on your age, body weight, and disease condition.
Q: Who should avoid using BESTOMAX IV INJECTION?
A: BESTOMAX IV INJECTION is not recommended for use in patients with severe kidney impairment, a history of liver problems or jaundice after taking penicillin antibiotics, or who are allergic to amoxicillin or clavulanic acid.
Q: What precautions must be taken while using BESTOMAX IV INJECTION?
A: Before receiving BESTOMAX IV INJECTION, inform your doctor if you have glandular fever, not been urinating regularly, convulsions (fits), large intestine inflammation, or suffering from kidney problems or liver disease.
Q: Is BESTOMAX IV INJECTION safe for kids?
A: BESTOMAX IV INJECTION should be used with caution in children as it may require dose modification.
Q: What should I do if I experience an allergic reaction after receiving BESTOMAX IV INJECTION?
A: Signs of an allergic reaction include rash, swelling of the face, lips, or throat, difficulty breathing, and joint pain. If you experience any of these symptoms, stop receiving the injection and seek immediate medical help.
Q: Can I drive after receiving BESTOMAX IV INJECTION?
A: It is advised not to drive or operate heavy machinery after receiving this injection, as it may cause dizziness or other side effects that impair your ability to perform such tasks.
Q: What happens if I miss a dose of BESTOMAX IV INJECTION?
A: Since the injection is administered by a healthcare professional, it’s unlikely you will miss a dose. However, if you are receiving treatment on an outpatient basis and miss a scheduled appointment, contact your healthcare provider for guidance.
Q: What should I do if I accidentally receive an overdose of BESTOMAX IV INJECTION?
A: Although this injection is administered by a healthcare professional, if an overdose occurs, symptoms such as nausea, diarrhea, or convulsions may appear. Contact your healthcare provider immediately for further management
References
1. KD Tripathi. Antimicrobial Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page-723, 724.
2. Justin Evans, Maryam Hannoodee, and Micah Wittler. Amoxicillin Clavulanate. National Centre for Biotechnology. NLM. National Institute of Health. stat pearls. December 2021. [Accessed on 8th October 2024] click here
3. GlaxoSmithKline Trading Services Limited Human Products and Regulatory Authority (HPRA). [Revised in March 2019] [Accessed on 8th October 2024] click here
4. Antibiotice SA. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 8th October 2024] click here
5. Istituto Biochimico Italiano G. Lorenzini S.p.A. Human Products and Regulatory Authority (HPRA). [Revised in May 2023] [Accessed on 8th October 2024] click here
6. GlaxoSmithKline Pharmaceuticals Limited. Amoxicillin + Clavulanic acid. [Revised in July 2022] [Accessed on 8th October 2024] click here
7. Medreich Limited. Amoxicillin + Clavulanic acid. [Revised in June 2015] [Accessed on 8th October 2024] click here
8. Cipla Limited. Amoxicillin + Clavulanic acid. [Revised in September 2019] [Accessed on 8th October 2024] click here
9. Augpen Injection (Amoxicillin + Clavulanic acid). Zuventus Healthcare Limited. [Accessed on 8th October 2024] click here
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