Sun Pharmaceutical Industries Ltd

Benfomet Plus Tablet 10'S

Nootropics And Neuro...
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    Introduction About BENFOMET PLUS TABLET

    BENFOMET PLUS TABLET is a combination of Alpha lipoic acid, Methylcobalamin, Benfotiamine, Pyridoxine which belongs to the group of medicines called Nutritional supplements and Vitamins respectively. It is used to manage diabetic neuropathy and helps to manage blood sugar levels.

    Diabetic neuropathy is a type of nerve damage occurring because of increased blood sugar levels which mainly occurs in feet and legs. Symptoms includes sharp pain, muscle weakness, severe sensitivity to touch, numbness, serious cases ulcers, infections, bone, and joint damages. Your doctor will ask you to monitor blood sugar levels regularly while taking management with BENFOMET PLUS TABLET.

    It is not recommended for use in patients who are pregnant, breastfeeding, and allergic to any of its components. BENFOMET PLUS TABLET is not recommended for use in children. Before taking BENFOMET PLUS TABLET inform your doctor if you have liver disease, thyroid disease, severe diabetes, thiamine deficiency. The most common side effects of taking BENFOMET PLUS TABLET involves nausea, vomiting, skin rashes, loss of appetite with fear of weight gaining (anorexia), loose motions. Consult your doctor if any of the side effects worsen or persists for a long duration.

    Uses Of BENFOMET PLUS TABLET

    • Used to manage diabetic peripheral neuropathy

    How BENFOMET PLUS TABLET Works

    BENFOMET PLUS TABLET is a combination of Alpha lipoic acid, Benfotiamine, Methylcobalamin and Pyridoxine. Alpha-lipoic acid easily enters the brain and the peripheral nerves and penetrates all parts of nerve cells to neutralise free radicals and stop the nerve tissue from ageing too quickly or degenerating chronically. Methylcobalamin improves the metabolism and antioxidant capability of brain and vascular endothelial cells to manage peripheral neuropathy. Pyridoxine helps to protect nerves from further damage, restores its structural and functional integrity and causes a recovery of function. Benfotiamine plays a role in glucose metabolism (conversion of glucose to energy) and helps to reduce blood sugar levels.

    How to use BENFOMET PLUS TABLET

    Take BENFOMET PLUS TABLET as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dosage and duration of BENFOMET PLUS TABLET for you depending on your age, body weight and severity of condition.

    Side Effects Of BENFOMET PLUS TABLET

    Rare

    • nausea
    • rashes
    • hives (urticaria)

    How To Manage Side Effects

    Nausea And Vomiting

    Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Keep yourself hydrated by drinking lots of fluids.

    Warning & Precautions

    Pregnancy

    Contraindicated

    BENFOMET PLUS TABLET is not recommended to take if you are pregnant. Consult your doctor before taking.

    Breastfeeding

    Contraindicated

    BENFOMET PLUS TABLET is not recommended to take if you are a breast-feeding women. Consult your doctor before taking BENFOMET PLUS TABLET.

    Alcohol

    Consult your doctor

    Inform your doctor if you have the habit of drinking too much alcohol before taking BENFOMET PLUS TABLET to avoid unwanted side effects.

    Liver

    Use with Caution

    BENFOMET PLUS TABLET should be used with caution in patients with liver diseases. Consult your doctor before taking BENFOMET PLUS TABLET.

    Allergy

    Contraindicated

    Do not take BENFOMET PLUS TABLET if you are allergic to Alpha lipoic acid, Benfotiamine, Methylcobalamin, Pyridoxine or any other ingredients of this medicine.

    Others

    Before taking BENFOMET PLUS TABLET inform your doctor if you have:

    • thyroid disorder
    • thiamine deficiency
    • high blood sugar levels

    Interactions

    A. Drug-Drug interactions:

    Before taking BENFOMET PLUS TABLET, inform your doctor if you are taking any of the following medicines:

    • medicines used to manage Parkinson’s disease (Ex. levodopa)
    • medicines used to manage tuberculosis (Ex. isoniazid, amino salicylic acid)
    • medicines used for birth control (Ex. estradiol)
    • medicines used to manage arthritis (Ex. penicillamine)
    • medicine used to manage bacterial infection (Ex. Neomycin, chloramphenicol)
    • medicines used to manage gastritis (Ex. cimetidine, ranitidine)
    • medicine used to manage gout (Ex. colchicine)

    B. Drug-Food interaction:

    Avoid taking BENFOMET PLUS TABLET with milk since milk decreases its effectiveness. Consult your doctor before taking.

    Overdosage:

    If you or anyone else accidentally takes too much of BENFOMET PLUS TABLET, consult your doctor immediately or visit the nearby hospital.

    Synopsis

    Drug :   Alpha lipoic acid, Methylcobalamin, Benfotiamine, Pyridoxine
    Pharmacological Category :   Nutritional supplements, Vitamins
    Therapeutic Indication :   Diabetic peripheral neuropathy
    Dosage Forms :   Tablet

    More Information

    • Keep BENFOMET PLUS TABLET out of reach of children
    • Store BENFOMET PLUS TABLET at room temperature

    FAQs About BENFOMET PLUS TABLET

    Q: What is BENFOMET PLUS TABLET used for?

    A: BENFOMET PLUS TABLET is a combination of Alpha lipoic acid, Methylcobalamin, Benfotiamine, Pyridoxine which belongs to the group of medicines called Nutritional supplements and Vitamins respectively. It is used to manage diabetic neuropathy and helps to manage blood sugar levels.

    Q: How BENFOMET PLUS TABLET works?

    A: BENFOMET PLUS TABLET is a combination of Alpha lipoic acid, Benfotiamine, Methylcobalamin and Pyridoxine. Alpha-lipoic acid easily enters the brain and the peripheral nerves and penetrates all parts of nerve cells to neutralise free radicals and stop the nerve tissue from ageing too quickly or degenerating chronically. Methylcobalamin improves the metabolism and antioxidant capability of brain and vascular endothelial cells to manage peripheral neuropathy. Pyridoxine helps to protect nerves from further damage, restores its structural and functional integrity and causes a recovery of function. Benfotiamine plays a role in glucose metabolism (conversion of glucose to energy) and helps to reduce blood sugar levels.

    Q: Is BENFOMET PLUS TABLET a multivitamin?

    A: BENFOMET PLUS TABLET is a multivitamin supplement indicated for neuropathy induced by diabetic peripheral neuropathy. It helps to boost and maintain the activity of damaged neurons.

    Q: Does BENFOMET PLUS TABLET manages nerve pain?

    A: Yes. BENFOMET PLUS TABLET is a dietary supplement that helps to boost and maintain the activity of damaged neurons and it helps to relieve pain. Consult your doctor before taking.

    Q: Does BENFOMET PLUS TABLET helps to manage cholesterol?

    A: BENFOMET PLUS TABLET has no significant effect on cholesterol levels or plasma triglycerides levels. Consult your doctor for advice.

    Q: How to take BENFOMET PLUS TABLET?

    A: Take BENFOMET PLUS TABLET exactly as advised by your doctor. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dosage and duration for you depending on your age, body weight and severity of condition.

    Q: What are the possible side effects of taking BENFOMET PLUS TABLET?

    A: The most possible side effects of taking BENFOMET PLUS TABLET involves nausea, vomiting, skin rashes, loss of appetite with fear of weight gaining (anorexia), diarrhoea. Consult your doctor if any of the symptoms are worsening.

    References

    1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology.6th edition. 2003. Page – 875.

    2. Mijnhout, G. S., A. Alkhalaf, N. Kleefstra, and H. J. Bilo. Alpha lipoic acid: a new treatment for neuropathic pain in patients with diabetes. Netherland Journal of Medicine. [Published in April 2010] [Accessed on 29th September 2022] https://www.researchgate.net/publication/43345855_Alpha_lipoic_acid_A_new_treatment_for_neuropathic_pain_in_patients_with_diabetes

    3. Hiep Nguyen; Vikas Gupta. Alpha-Lipoic Acid. National library of medicine. NIH. National centre for biotechnology information. Pubmed.gov. [Revised on 20th November 2021] [Accessed on 29th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK564301/

    4. Han, Yajuan, Min Wang, Jie Shen, Zhen Zhang, Min Zhao, Jing Huang, Youming Chen, Zhi Chen, Yulan Hu, and Yubing Wang. Differential efficacy of Methylcobalamin and alpha-lipoic acid treatment on symptoms of diabetic peripheral neuropathy. National centre for biotechnology information. pubmed.gov. [Revised on 30th November 2016] [Accessed on 29th September 2022] https://pubmed.ncbi.nlm.nih.gov/27901334/

    5. Levin, Ellis R., Thomas A. Hanscom, Mark Fisher, Walter A. Lauvstad, Alec Lui, Ann Ryan, David Glockner, and Seymour R. Levin. The influence of pyridoxine in diabetic peripheral neuropathy. NIH. National centre for biotechnology information. pubmed.gov (1981). [Accessed on 29th September 2022] https://pubmed.ncbi.nlm.nih.gov/6751736/

    6. Stracke, H., W. Gaus, U. Achenbach, K. Federlin, and R. G. Bretzel. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. NIH. National centre for biotechnology information. pubmed.gov. [Published on 13th May 2008] [Accessed on 29th September 2022] https://pubmed.ncbi.nlm.nih.gov/18473286/

    7. Kathleen A Head. Type-I diabetes: Prevention of the disease and its complications. Thorne research (1998). [Accessed on 29th September 2022] https://altmedrev.com/wp-content/uploads/2019/02/v2-4-256.pdf

    8. Jayaram, S., Akash Khobragade, and Deepak Langade. Methylcobalamin, Pyridoxine and Nicotinamide in Diabetic Neuropathy: A Review. Indian J Clin Practice. (2009). [Accessed on 29th September 2022] https://www.researchgate.net/publication/289916259_Methylcobalamin_pyridoxine_and_nicotinamide_in_diabetic_neuropathy_A_review

    9. NourEldin R. Abosamak; Vikas Gupta. Vitamin B6 (Pyridoxine). Abosamak, NourEldin R., and Vikas Gupta. Vitamin B6 (pyridoxine). National centre for biotechnology information.pubmed.gov. [Published in January 2022] [Accessed on 29th September 2022] https://www.ncbi.nlm.nih.gov/books/NBK557436/

    10. Royal National Institute of Blind People. Electronic Medicines Compendium (EMC). [Revised in March 2015] [Accessed on 29th September2022] https://www.medicines.org.uk/emc/files/pil.1208.pdf

    11. Panacea Biotec Ltd. Methylcobalamin + Benfotiamine + Alpha Lipoic Acid + Folic acid + Pyridoxine Hydrochloride. [Revised on 15th February 2019] [Accessed on 29th September 2022] https://media.panaceabiotec.com/documents/2019/7/27/ProductMonohraph-MYELOGENFORTENU12July2019.pdf

    12. Getz pharma ltd. Methylcobalamin. [Accessed on 29th September 2022] https://getzpharma.com/wp-content/uploads/2016/08/Nervon-Range-Leaflet-Export-GA.pdf

    13. Mauermann Arzneimittel KG. Benfotiamine. [Revised in October 2021] [Accessed on 29th September 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_14350_ENG.pdf

    14. Invacic. sinovi. D.o.o. Alpha lipoic acid. [Accessed on 29th September 2022] http://undoctorenlinea.com/pdf/alphalipoin/Alphalipoin.pdf

    Author Details

    Written By Dr. Janet.C - Pharm.D
    Reviewed For Accuracy By Dr. Sankara Babu Gorle - MBBS, MD (Pharmacology)
    Last updated on 10 Mar 2023 | 09:43 AM(IST)
    Lab updated