BAXALTA HUMAN ALBUMIN 20% Solution 100ml

INTRODUCTION

BAXALTA HUMAN ALBUMIN 20% SOLUTION contains Human albumin that belongs to the group of medicines called Plasma expanders. It is used to restore and maintain blood volume in hypovolemia (reduced blood volume in the circulatory system or extracellular fluid of the body, characterized by symptoms such as sweating, light-headedness, confusion, fatigue or decreased blood pressure).

BAXALTA HUMAN ALBUMIN 20% SOLUTION is also used to treat hypoalbuminemia (low levels of albumin protein that's responsible for keeping fluid in your blood vessels) in burns, Adult Respiratory Distress Syndrome (ARDS) and nephrosis (excess protein in urine). BAXALTA HUMAN ALBUMIN 20% SOLUTION can also be used during cardiopulmonary bypass surgery and Hemolytic Disease of the Newborn (a blood disorder in a new-born).

BAXALTA HUMAN ALBUMIN 20% SOLUTION is not recommended for use if you have severe anemia or heart failure with normal or increased intravascular volume. Before receiving BAXALTA HUMAN ALBUMIN 20% SOLUTION, inform your doctor if you have high blood pressure, enlarged veins in the gut, water on the lungs, tendency to bleed or decreased or no urine production.

Your doctor will monitor you to check your circulatory situation with the electrolyte balance and blood volume. BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in pregnant and breastfeeding women so, consult your doctor before receiving it. Your doctor will decide a proper dose of BAXALTA HUMAN ALBUMIN 20% SOLUTION for your child based on their body weight.

The most common side effects of receiving BAXALTA HUMAN ALBUMIN 20% SOLUTION are anaphylactoid type reactions (skin reactions like hives, itching and flushed or pale skin, low blood pressure, wheezing and trouble breathing, a weak and rapid pulse). Call your doctor if any of the symptoms get worse over time.

USES OF BAXALTA HUMAN ALBUMIN 20% SOLUTION

Used to treat

• hypovolemia
• hypoalbuminemia in burns, Adult Respiratory Distress Syndrome (ARDS) and nephrosis
• cardiopulmonary bypass surgery
• Hemolytic Disease of the Newborn

HOW BAXALTA HUMAN ALBUMIN 20% SOLUTION WORKS

BAXALTA HUMAN ALBUMIN 20% SOLUTION contains human albumin which has properties that are equivalent to the normal human plasma in equal quantities. It works by increasing the circulating plasma volume by an amount approximately equal to the volume infused. The infused albumin stays for longer hours in the body and takes less time in bringing blood volume to normal levels.

DIRECTIONS FOR USE

BAXALTA HUMAN ALBUMIN 20% SOLUTION will be given to you only by a doctor or a nurse into the vein. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF BAXALTA HUMAN ALBUMIN 20% SOLUTION

HOW TO MANAGE SIDE EFFECTS

Nausea:

Take regular sips of a cold drink. Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. If symptom persists, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in women who are pregnant or planning for pregnancy. Consult your doctor before receiving it.

BREASTFEEDING

BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in breastfeeding mothers. Consult your doctor before receiving it.

DRIVING AND USING MACHINES

BAXALTA HUMAN ALBUMIN 20% SOLUTION has no known effects on the ability to drive or use machines. Consult your doctor for advice.

KIDNEY

BAXALTA HUMAN ALBUMIN 20% SOLUTION is not recommended for use in patients with chronic kidney insufficiencies due to the potential for accumulations of aluminium. BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in patients having renal and post-renal anuria (decreased or no urine production). Consult your doctor before receiving it.

ALLERGY

Do not receive BAXALTA HUMAN ALBUMIN 20% SOLUTION if you are allergic to albumin preparations or any of the other ingredients of this medicine.

LUNGS

BAXALTA HUMAN ALBUMIN 20% SOLUTION is not recommended for use in patients with pulmonary edema (presence of excess fluid in the lungs). Consult your doctor before receiving it.

HEART DISEASE

BAXALTA HUMAN ALBUMIN 20% SOLUTION is not recommended for use in patients suffering from heart failure with normal or increased intravascular volume. BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in patients with high blood pressure. Consult your doctor before receiving it.

INTERACTIONS

A. Drug-Drug Interactions:

Before receiving BAXALTA HUMAN ALBUMIN 20% SOLUTION, inform your doctor if you are taking, have taken or might take any other medicine, including prescription, non-prescription or any herbal medicine.

Overdosage:

BAXALTA HUMAN ALBUMIN 20% SOLUTION will be given to you only by a doctor or nurse in a hospital and so it is unlikely to receive an overdose. However, if you experience any unusual symptoms, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

MORE INFORMATION

• Keep BAXALTA HUMAN ALBUMIN 20% SOLUTION out of reach in children
• Store BAXALTA HUMAN ALBUMIN 20% SOLUTION at room temperature

FAQs ABOUT BAXALTA HUMAN ALBUMIN 20% SOLUTION

Can BAXALTA HUMAN ALBUMIN 20% SOLUTION be given to infants?

The safety of BAXALTA HUMAN ALBUMIN 20% SOLUTION has been demonstrated in children provided the dose is appropriate for body weight. Consult your child’s doctor for advice. The doctor will decide a proper dose or select a suitable alternative treatment for your child.  

What happens if you take more BAXALTA HUMAN ALBUMIN 20% SOLUTION than your required dose?

BAXALTA HUMAN ALBUMIN 20% SOLUTION will be given to you only by a doctor or nurse in a hospital and so it is unlikely to receive an overdose. However, if you experience anything unusual like headache, difficulty breathing, a fluid build-up in a neck vein, increased blood or vein pressure, water on the lungs (symptoms of overdose), consult your doctor immediately or visit the nearby hospital.

What if I miss a dose of BAXALTA HUMAN ALBUMIN 20% SOLUTION?

Please stick to the prescribed schedule as agreed with your doctor for optimal efficacy of BAXALTA HUMAN ALBUMIN 20% SOLUTION treatment. Tell your doctor whenever you miss any dose.

Can I stop receiving BAXALTA HUMAN ALBUMIN 20% SOLUTION on my own?

Continue receiving BAXALTA HUMAN ALBUMIN 20% SOLUTION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. Contact your doctor in such situation.

Is BAXALTA HUMAN ALBUMIN 20% SOLUTION safe to use in pregnancy?

BAXALTA HUMAN ALBUMIN 20% SOLUTION should be used with caution in pregnancy. If you are pregnant, think you may be pregnant or are planning for a baby, contact your doctor before taking it. Inform your doctor immediately if you become pregnant during treatment with BAXALTA HUMAN ALBUMIN 20% SOLUTION.

REFERENCES

1. Sean C Sweetman. Blood Products Plasma Expanders and Haemostatics. Martindale The Complete Drug Reference. 36th edition. Page- 1052.

2. Alejandro Campos Munoz, Nitesh K. Jain, Mohit Gupta. Albumin Colloid. NIH National Library of Medicine. National Centre for Biotechnology Information. PMC PubMed Central. January 2022. [Accessed 13th July 2022]. https://www.ncbi.nlm.nih.gov/books/NBK534241/

3. Ho JJ, Adnan AS, Kueh YC, Ambak NJ, Van Rostenberghe H, Jummaat F. Human albumin infusion for treating oedema in people with nephrotic syndrome (Review). National Library of Medicine. National Centre for Biotechnology Information. Cochrane Library. 2019. [Accessed on 13th July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699680/pdf/CD009692.pdf

4. Biotest Pharma GmbH. European Medicines Agency (EMA). [Revised in February 2020] [Accessed on 13th July 2022]. https://www.medicines.org.uk/emc/files/pil.577.pdf ; https://www.medicines.org.uk/emc/files/pil.581.pdf

5. Baxalta Incorporated. BUMINATE (albumin human injection, solution). [Revised in July 2017] [Accessed on 13th July 2022]. https://www1.ndmctsgh.edu.tw/pharm/pic/medinsert/005HUM01E.pdf

6. Grifols Biologicals LLC. ALBUTEIN 5% (albumin [human]). [Revised in June 2018]. [Assessed 13th July 2022]. https://www.fffenterprises.com/assets/downloads/product-information/grifols/pi-ALBUTEIN-5.pdf

USEFUL DIAGNOSTIC TESTS

• Complete Blood Count (CBC)
• Kidney Function Test

AUTHOR DETAILS

Written By Dr. Aswin Kumar.M.S, BDS
Last updated on 31 Mar 2023 | 04:13 PM(IST)