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Introduction About BANDRONE 6MG INJECTION
BANDRONE 6MG INJECTION contains Ibandronic acid, which belongs to the group of medicines called Bisphosphonates. It is used in adults with breast cancer that has spread to bones to manage bone fractures and other bone problems that may need surgery or radiotherapy. Breast cancer is a cancer that forms in the cells of the breasts. Symptoms include lumps in the breast and changes in size, shape, and skin over the breast.
BANDRONE 6MG INJECTION is not recommended for use in patients who have or have had low blood calcium levels. Before receiving BANDRONE 6MG INJECTION, inform your doctor if you have or have ever had problems with your mouth or teeth (poor dental health or gum disease), have not had a dental checkup for a long time, are a smoker, have cancer, high or low levels of vitamin D, calcium, or other minerals, and have kidney disease or heart problems.
Prior to the management, your doctor may ask you to undergo a dental examination and advise you to maintain good oral hygiene, such as regular teeth brushing, and receive routine dental check-ups.
BANDRONE 6MG INJECTION is not recommended for use by pregnant and breastfeeding women. BANDRONE 6MG INJECTION is not recommended for use in children below 18 years of age.
The most common side effects of receiving BANDRONE 6MG INJECTION are flu-like symptoms, stomach pain, headache, bruising, tooth, and skin problems. Inform your physician if any of the symptoms worsen.
Uses Of BANDRONE 6MG INJECTION
It is used by adults to manage:
- breast cancer that has spread to bones
- bone fracture
- bone problems that may need surgery
How BANDRONE 6MG INJECTION Works
BANDRONE 6MG INJECTION works by reducing the amount of calcium that is lost from bones, inhibiting osteoclast activity, and reducing bone resorption and turnover, with a net gain in bone mass. Thus, it helps to stop your bones from getting weaker.
How to use BANDRONE 6MG INJECTION
BANDRONE 6MG INJECTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the right dose and duration depending on your age, body weight, and disease condition.
Side Effects Of BANDRONE 6MG INJECTION
Common
- flu-like symptoms (fever, shaking and shivering, feeling of discomfort, fatigue, bone pain, and aching muscles and joints)
- rise in body temperature.
- stomach pain, indigestion, vomiting, or diarrhea
- low calcium or phosphate levels in the blood
- heart rhythm problems
- pain in bones or muscles
- headache, feeling dizzy or weak
- thirsty, sore throat, taste changes
- swollen legs or feet
- joint pain, arthritis, and other joint problems
- problems with the parathyroid gland
- bruising and infections
- cataract of the eye
- skin and tooth problems
Uncommon
- shaking or shivering
- low body temperature
- cerebrovascular disorder (stroke or brain bleeding)
- heart and circulatory problems (including palpitations, heart attacks, high blood pressure, and varicose veins)
- anemia
- lymphoedema (swelling in the body’s tissues)
- fluid in the lungs
- gastroenteritis or gastritis
- gallstones
- unable to pass urine
- cystitis (inflammation of the bladder)
- migraine
- pain in the nerves (damaged nerve root)
- deafness
- increased sensitivity to sound, taste, touch, or smell
- difficulty swallowing
- mouth ulcers, swollen lips, oral thrush
- itching or tingling skin around the mouth
- pelvic pain, or discharge, pain in the vagina, itching.
- benign skin neoplasm (skin growth)
- memory loss
- difficulty sleeping, anxiety, change in mood, emotional instability
- skin rash
- weight loss
- injury or pain at the site of the injection
- hair loss
Rare
- persistent eye pain and inflammation
- new pain, weakness, or discomfort in the thigh, hip, or groin, and early signs of a possible unusual fracture of the thigh bone.
Consult your doctor if you experience any of the following side effects:
- shortness of breath, a tight feeling in the throat, swelling of the tongue, dizziness, loss of consciousness, redness or swelling of the face, body rash, nausea, and vomiting
- persistent eye pain and inflammation.
- new pain, weakness, or discomfort in your thigh, hip, or groin (possible unusual fracture of the thigh bone)
- any problems with the mouth or teeth (loose teeth, pain or swelling, or non-healing of sores or discharge could be signs of osteonecrosis of the jaw)
How To Manage Side Effects
Diarrhea
Drink lots of fluids, such as water, to keep yourself hydrated. Inform your doctor if diarrhea does not improve.
Dizziness Or Drowsiness
Lie down until dizziness passes away, then move slowly and carefully. Take plenty of rest and drink plenty of fluids. If the symptom does not improve, inform your doctor.
Headache
Apply a hot or cold water bag to your head. Try taking enough rest and sleeping. Avoid watching a bright screen for a long time. If the symptom does not improve, inform your doctor.
Nausea And Vomiting
Stick to a simple meal plan. Avoid eating oily, fried, or spicy foods. Don’t lie down or sleep immediately after eating. If the symptom does not improve, inform your doctor.
Stomach Pain
Try to take a rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, inform your doctor.
Warning & Precautions
Pregnancy
ContraindicatedBANDRONE 6MG INJECTION is not recommended for use by pregnant women. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Breastfeeding
ContraindicatedBANDRONE 6MG INJECTION is not recommended for use by breastfeeding women. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Driving and Using Machines
Use with CautionBANDRONE 6MG INJECTION has no effect on your ability to drive and use machines. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Kidney
Use with CautionBANDRONE 6MG INJECTION should be used with caution in patients with kidney disease. Your dose will be adjusted in case of moderate to severe kidney disease. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Liver
Use with CautionBANDRONE 6MG INJECTION should be used with caution in patients with liver disease. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Allergy
ContraindicatedDo not receive BANDRONE 6MG INJECTION if you are allergic to Ibandronic acid or any of the other ingredients in this medicine.
Lungs
Use with CautionBANDRONE 6MG INJECTION should be used with caution in patients with lung diseases. Contact your doctor before receiving BANDRONE 6MG INJECTION.
Heart Disease
Use with CautionBANDRONE 6MG INJECTION should be used with caution in patients with heart problems. Consult your doctor before receiving BANDRONE 6MG INJECTION.
Use In Pediatrics
ContraindicatedBANDRONE 6MG INJECTION is not recommended for use in children and adolescents below 18 years of age. Consult the child’s doctor for advice.
Others
BANDRONE 6MG INJECTION is not recommended for use if you:
- have low blood calcium levels
Before receiving BANDRONE 6MG INJECTION, inform your doctor if you:
- have any problems with the mouth or teeth (poor dental health or gum disease)
- have not had a dental check-up or not received dental care for a long time
- are a smoker
- have cancer
- are under dental management or will undergo dental surgery (like tooth extractions)
- have abnormal levels of vitamin D, calcium, or other minerals
Interactions
A. Drug-Drug interactions:
Before receiving BANDRONE 6MG INJECTION, inform your doctor if you have received or are taking any of the following medicines:
- corticosteroids Ex. prednisolone or dexamethasone (medicines used to manage inflammation)
- aminoglycoside Ex. gentamicin injection (medicines used for bacterial infections)
Overdosage:
BANDRONE 6MG INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. However, contact your physician or nurse if you experience any unusual symptoms.
Synopsis
| Drug | : | Ibandronic acid |
| Pharmacological Category | : | Bisphosphonates |
| Therapeutic Indication | : | Breast cancer spreads to bones, reduces bone fracture, and Bone problems needing surgery |
| Dosage Forms | : | Tablet, Injection |
More Information
- Store at room temperature
FAQs About BANDRONE 6MG INJECTION
Q: What lifestyle changes should I follow while receiving BANDRONE 6MG INJECTION?
A: While receiving BANDRONE 6MG INJECTION, your doctor might advise you to maintain a healthy lifestyle, like eating a balanced diet rich in calcium and vitamin D, walking or any other weight-bearing exercise, maintaining good oral hygiene, and avoiding smoking and alcohol consumption.
Q: How does BANDRONE 6MG INJECTION work?
A: BANDRONE 6MG INJECTION works by reducing the amount of calcium that is lost from bones, inhibiting osteoclast activity, and reducing bone resorption and turnover, with a net gain in bone mass. Thus, it helps to stop your bones from getting weaker.
Q: Can BANDRONE 6MG INJECTION be used with children?
A: No, BANDRONE 6MG INJECTION is not recommended for use in children and adolescents below 18 years of age, as the safety and effectiveness of this medicine have not been established. Consult the child’s doctor for advice.
Q: Can BANDRONE 6MG INJECTION be used in pregnant women?
A: No, BANDRONE 6MG INJECTION is not recommended for use in pregnant and breastfeeding women. If you think you are pregnant or are planning to get pregnant, inform your doctor before receiving BANDRONE 6MG INJECTION.
Q: Is BANDRONE 6MG INJECTION safe to use in kidney patients?
A: BANDRONE 6MG INJECTION should be used with caution in patients with kidney disease. Your dose will be adjusted in case of moderate to severe kidney disease. Consult your doctor before receiving it.
References
1. KD. Tripathi. Drugs Affecting Calcium Balance. Essentials of medical pharmacology. Seventh edition. 2013. Page-343.
2. Maurizio Rossini, Giovanni Orsolini, Silvano Adami, Vidya Kunnathully, Davide Gatti. Osteoporosis treatment: why ibandronic acid. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. July 2013 [Accessed on 2nd February 2024] https://pubmed.ncbi.nlm.nih.gov/23650954/
3. Chugai Pharmaceutical. Phase II/III Clinical Study of R484iv (Ibandronic Acid) for Primary Osteoporosis. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised in August 2012] [Accessed on 2nd February 2024] https://clinicaltrials.gov/ct2/show/NCT00447915
4. Atnahs Pharma Denmark ApS. Electronic Medicines Compendium (EMC). [Revised in January 2023] [Accessed on 2nd February 2024] https://www.medicines.org.uk/emc/files/pil.9375.pdf
Useful Diagnostic Tests
- Calcium
- Vitamin D 1,25 Dihydroxy
- Extended Arthritis Care
- Comprehensive Arthritis Care
- Basic Bone Care
- Advance Bone Care
- Comprehensive Bone Care
- Esr Automated
- Phosphorus-Inorganic, Serum
- Basic Arthritis Care Plan
- Bone Strength Package
- Arthritis Profile-Basic
- Arthritis Profile-Advanced
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