Glenmark Pharmaceuticals Ltd

Ascoril LS Expectorant 100ml

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    Introduction About ASCORIL LS EXPECTORANT

    Ascoril LS Expectorant 100 ml is a commonly prescribed cough formulation designed for situations where cough is associated with thick mucus and breathing discomfort. It contains a combination of Ambroxol, Guaiphenesin, and Levosalbutamol, which together support mucus loosening, mucus clearance, and airway comfort. This expectorant is often recommended when chest congestion, wheezing, or difficulty in clearing phlegm affects daily breathing comfort, especially during respiratory infections or airway irritation.

    The formulation works by addressing multiple aspects of mucus-related cough. Ambroxol helps reduce the thickness of mucus, making it easier to clear from the airways. Guaiphenesin supports the natural expulsion of loosened mucus by increasing airway secretions, while Levosalbutamol helps relax airway muscles, which may improve airflow and ease breathing effort. Because of this combined action, Ascoril LS Expectorant is generally considered suitable for individuals experiencing productive cough with chest tightness or bronchospasm-like symptoms, as advised by a healthcare professional.

    Ascoril LS Expectorant should be taken exactly as directed by a doctor. The bottle should be shaken well before use, and the dose is usually measured using a calibrated cup or spoon. The timing and quantity depend on factors such as age, body weight, and clinical condition. It can be taken with or without food but following consistent timing may help maintain regular symptom control. Patients are advised not to exceed the recommended dose and to avoid self-adjusting the duration of use without medical guidance.

    Certain precautions are important while using this medicine. Caution is advised in individuals with heart conditions, high blood pressure, thyroid disorders, diabetes, liver or kidney concerns, or seizure disorders. Use during pregnancy or breastfeeding should only be considered if the expected benefit outweighs potential risks and under medical supervision. Commonly reported side effects may include nausea, vomiting, headache, dizziness, or mild drowsiness, which are usually temporary. If symptoms persist or worsen, medical advice should be sought promptly.

    Uses Of ASCORIL LS EXPECTORANT

    • Relief from productive (wet) cough with thick, sticky mucus
    • Helps reduce chest congestion and ease breathing discomfort
    • Used in respiratory conditions such as bronchitis and other lower respiratory tract infections

    Benefits of ASCORIL LS EXPECTORANT

    Ascoril LS Expectorant for Cough Management

    Ascoril LS Expectorant is commonly used as part of cough care where mucus build-up contributes to discomfort. It supports cough management by helping reduce chest congestion and improving airflow through the airways. By making mucus easier to move, it allows coughing to feel more productive rather than frequent and tiring. This supportive action helps reduce throat irritation caused by repeated coughing. It is often considered in situations where cough is associated with thick respiratory secretions.

    Ascoril LS Expectorant for Mucus Clearance

    Ascoril LS Expectorant plays an important role in supporting mucus clearance from the respiratory tract. It helps reduce the thickness and stickiness of mucus, allowing it to move more freely within the airways. Improved mucus movement supports natural clearance through coughing and breathing. This process helps keep air passages clearer and reduces the sensation of chest heaviness. Effective mucus clearance also supports more comfortable breathing during respiratory discomfort.

    How ASCORIL LS EXPECTORANT Works

    Mechanism of Action of Ascoril LS Expectorant

    Ascoril LS Expectorant works through a combination-based approach that targets thick mucus and breathing difficulty in the airways. Each active component plays a distinct role to support smoother airflow. One component helps thin and loosen mucus, making it less sticky. Another supports the movement of loosened mucus upward through the respiratory tract. Additionally, a bronchodilating component helps relax the airway muscles, allowing air to pass more freely. Together, these actions improve mucus clearance and support easier breathing. 

    How to use ASCORIL LS EXPECTORANT

    How to Take Ascoril LS Expectorant 100ml

    • Take the syrup exactly as prescribed by your healthcare professional.
    • Use a measuring cup or spoon to ensure the correct dose.
    • Shake the bottle well before each use to mix the ingredients evenly.
    • Take the syrup orally, directly from the measuring device.
    • Follow the prescribed frequency and timing (morning, afternoon, evening) as advised.
    • Do not exceed the recommended dose without consulting your doctor.

    What if I forgot to take ASCORIL LS EXPECTORANT

    • Take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose.
    • Do not double the dose to make up for the missed one. 
    • Continue with your regular dosing schedule as advised by your healthcare professional.
    • If you are unsure what to do, consult your doctor or pharmacist for guidance.

    Overdose

    If someone accidentally takes more than the recommended amount of Ascoril LS Expectorant, seek medical advice immediately or visit the nearest healthcare facility. 

    Side Effects Of ASCORIL LS EXPECTORANT

    Common Side Effects of Ascoril LS Expectorant

    • increased heart rate
    • dizziness, drowsiness
    • headache
    • nausea, vomiting
    • sweating

    When to Seek Medical Attention?

    Stop taking Ascoril LS Expectorant and inform your doctor immediately if you experience any of the following side effects:

    • severe skin lesions such as Stevens-Johnson syndrome and toxic epidermal necrolysis (TEN, Lyell's syndrome)

    How To Manage Side Effects

    Dizziness Or Drowsiness

    • Stay well-hydrated: Drink enough water throughout the day. Dehydration is one of the most common causes of dizziness.
    • Eat regular meals: Low blood sugar can trigger dizziness, so avoid skipping meals and include healthy snacks like fruits or nuts.
    • Sit or lie down immediately: If you feel dizzy, rest in a comfortable position to prevent falls or injuries.
    • Take slow, deep breaths: This helps improve oxygen flow and reduces dizziness caused by anxiety or stress.
    • Have an electrolyte-rich drink: Coconut water or oral rehydration solutions can help restore salt and mineral balance.
    • Use a cool compress: Applying a damp, cool cloth to your forehead may help calm dizziness.
    • Practice balance exercises: Gentle movements like yoga or tai chi can help improve body coordination over time.
    • Avoid sudden movements: Stand up slowly from sitting or lying positions to prevent a sudden drop in blood pressure.

    Nausea And Vomiting

    • Ginger: Ginger tea, ginger water, or a small piece of fresh ginger can help calm the stomach and reduce the urge to vomit.
    • Lemon: Sipping warm lemon water or smelling fresh lemon may help ease nausea and freshen the stomach.
    • Mint (Pudina): Mint tea or chewing fresh mint leaves may help soothe the stomach and reduce queasiness.
    • Cold Water or Ice Chips: Taking small sips of cold water or sucking on ice chips can help reduce nausea.
    • Fennel Seeds (Saunf): Chewing fennel seeds or drinking fennel seed water may help relieve nausea and bloating.
    • Clove: Sucking on a clove or drinking clove tea can help reduce the uneasy feeling in the stomach.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    Ascoril LS Expectorant should be used during pregnancy only if a healthcare professional determines that the potential benefits outweigh the potential risks to the foetus.       

    Breastfeeding

    Consult your doctor

    Limited information is available regarding the use of Ascoril LS Expectorant in breastfeeding women. Medical guidance is advised before use.

    Driving and Using Machines

    Use with Caution

    This medicine may cause dizziness in some individuals. If you experience dizziness, avoid driving or operating machinery that requires full attention. 

    Kidney

    Use with Caution

    Ascoril LS Expectorant should be used carefully in patients with kidney disease under medical supervision.  

    Liver

    Use with Caution

    Patients with liver conditions should use this medicine with caution and follow their healthcare provider’s guidance. 

    Allergy

    Contraindicated

    Do not use Ascoril LS Expectorant if you are allergic to Ambroxol, Guaiphenesin, Levo salbutamol, or any other ingredient in the syrup. 

    Lungs

    Use with Caution

    Patients with acute severe asthma or chronic impairment of mucus production should use this medicine carefully and under medical advice. 

    Heart Disease

    Consult your doctor

    Ascoril LS Expectorant is not recommended for patients with heart disease or at risk of heart attack. Patients with high blood pressure should also use it cautiously under supervision. 

    Use In Pediatrics

    Consult your doctor

    The appropriate dose for children depends on age, body weight, and symptom severity, and should be prescribed by a healthcare professional. 

    Use In Geriatrics

    Consult your doctor

    Clinical studies did not include enough patients aged 65 and above to confirm if their response differs from younger adults. Medical guidance is recommended.

    Other Warnings for ASCORIL LS EXPECTORANT

    Before taking Ascoril LS Expectorant, inform your doctor if you:

    • Have uncontrolled juvenile diabetes mellitus
    • Have hyperthyroidism
    • Have seizures  
    • Have gastric ulcers

    Who should not take ASCORIL LS EXPECTORANT

    Ascoril LS Expectorant is not recommended for use if you:

    • Have thyrotoxicosis
    • Have hereditary problems with fructose intolerance
    • Have porphyria  

    Safety Advice

    • Avoid self-adjusting the dose: Never change the dose or frequency on your own. Always follow your doctor’s instructions.
    • Check for interactions: Inform your doctor if you are taking other medicines, including over-the-counter cough or cold products, to prevent potential interactions.
    • Monitor symptoms: If symptoms persist or worsen, contact your healthcare professional promptly.
    • Do not share your medicine: This syrup is prescribed for individual use only and should not be shared with others.
    • Avoid expired medication: Do not use the syrup past its expiry date.
    • Use proper measuring devices: Avoid using household spoons; always use the calibrated cup or spoon provided to ensure accurate dosing.
    • Observe for unusual reactions: If you notice unexpected reactions such as severe dizziness, rash, or unusual breathing difficulty, seek medical attention immediately.

    Diet and Lifestyle Advice

    • Stay hydrated: Drink plenty of water and fluids throughout the day to help keep mucus thin and easier to clear.
    • Maintain a balanced diet: Include fruits, vegetables, and fibre-rich foods to support overall respiratory and immune health.
    • Avoid irritants: Minimize exposure to smoke, dust, strong fragrances, and polluted environments, which can aggravate cough or mucus production.
    • Rest adequately: Ensure sufficient sleep and rest to support the body’s natural recovery processes.
    • Humidify the air: Using a humidifier or taking warm showers may help keep the airways moist and reduce discomfort.
    • Limit mucus-thickening foods: Some people find that very fatty, fried, or dairy-heavy meals can make mucus thicker; observe how your body responds.
    • Regular gentle activity: Mild physical activity, as advised by your doctor, can help maintain lung function and overall health.
    • Follow medical instructions: Always take the syrup as prescribed and consult your doctor before making lifestyle changes.

    1. Ascoril LS Expectorant vs Ambroxol Syrup

    Aspect

    Ascoril LS Expectorant

    Ambroxol Syrup

    Type of formulation

    Combination expectorant with bronchodilator support

    Single-ingredient mucolytic syrup

    Key ingredients

    Ambroxol + Guaifenesin + Levosalbutamol

    Ambroxol only

    How it works (mechanism context)

    Works through multiple actions mucus thinning, mucus clearance support, and relaxation of airway smooth muscles

    Works mainly by reducing the thickness and stickiness of mucus

    Action focus

    Acts on mucus consistency, airway clearance, and airflow comfort

    Acts primarily on mucus breakdown

    Central vs airway action

    Supports both airway muscle relaxation and mucus movement

    Focuses on mucus handling within the airways

    Suitability context

    Commonly considered when cough is associated with thick mucus and breathing discomfort

    Commonly considered when mucus is thick but breathing effort is not prominent

    Complexity of formulation

    Multi-component formulation requiring careful dosing

    Simpler formulation with a single active ingredient

    Use guidance

    Should be taken strictly as advised by a healthcare professional due to combination ingredients

    Dosing is generally simpler but still requires medical advice

    Patient decision consideration

    Chosen when broader respiratory support is required

    Chosen when targeted mucus thinning support is sufficient

    Drug - Drug interaction

    1. Beta-blockers (e.g., propranolol, atenolol)

    • Interaction: Beta-blockers may reduce the airway-relaxing effect of levosalbutamol, potentially limiting breathing comfort.
    • Management: Doctors may avoid combining these medicines or closely monitor breathing symptoms and heart function if both are required.

    2. Other bronchodilators or asthma medicines

    • Interaction: Using multiple bronchodilators together may increase the risk of palpitations, tremors, or restlessness.
    • Management: Dose adjustment and monitoring are usually recommended. Patients should avoid adding inhalers or syrups without medical advice.

    3. Monoamine oxidase inhibitors (MAOIs) and certain antidepressants

    • Interaction: These medicines may enhance the cardiovascular effects of levosalbutamol, such as increased heart rate or blood pressure changes.
    • Management: A sufficient gap between therapies is often advised. Inform your doctor if you have recently used antidepressants.

    4. Diuretics (water tablets)

    • Interaction: Combined use may increase the risk of low potassium levels, which can affect muscle and heart function.
    • Management: Doctors may monitor electrolyte levels and advise dietary or medical adjustments if needed.

    5. Cardiac medicines (e.g., digoxin)

    • Interaction: Changes in potassium levels due to levosalbutamol may influence the effects of certain heart medicines.
    • Management: Regular monitoring and dose review may be required in patients with existing heart conditions.

    6. Cough suppressants (antitussives)

    • Interaction: Using cough suppressants alongside Ascoril LS may interfere with mucus clearance from the airways.
    • Management: Such combinations are generally avoided unless specifically advised by a healthcare professional.

    7. Antibiotics

    • Interaction: Ambroxol may increase lung tissue penetration of some antibiotics, altering their distribution.
    • Management: This interaction is usually considered clinically acceptable but should still be supervised by a doctor.

    Drug - Food interaction

    1. Caffeine-containing foods and beverages (coffee, tea, energy drinks)

    • Interaction: Caffeine may increase restlessness, nervousness, or a fast heartbeat when taken along with levosalbutamol.
    • Management: Limit excessive caffeine intake during the course of use, especially if you notice palpitations or shakiness.

    2. High-sugar foods

    • Interaction: The syrup formulation contains sweeteners, which may affect blood sugar control when combined with high-sugar foods, particularly in people with diabetes.
    • Management: Monitor blood sugar levels as advised and maintain a balanced diet. Inform your doctor if you have diabetes.

    3. Very cold foods or drinks

    • Interaction: Cold foods or beverages may temporarily irritate the throat and airways, increasing cough sensitivity in some individuals.
    • Management: Opt for room-temperature or warm fluids to support throat comfort and mucus clearance.

    Synopsis

    Drug

    Ambroxol, Guaiphenesin, Levosalbutamol

    Pharmacological Category

    Mucolytic, Expectorant, Bronchodilators

    Therapeutic Indication

    Productive cough

    Dosage Forms

    Expectorant, Syrup

    More Information

    Storage

    • Keep in a cool, dry place
    • Store out of reach of children and pets

    FAQs About ASCORIL LS EXPECTORANT

    Q: What is Ascoril LS Expectorant used for?

    A: Ascoril LS Expectorant is commonly used to relieve productive coughs associated with conditions like bronchitis and bronchial asthma. It is also suitable for situations where thick mucus, wheezing, or chest congestion is present, helping to make mucus easier to clear from the airways.

    Q: How should Ascoril LS Expectorant be taken?

    A: Take Ascoril LS Expectorant exactly as prescribed by your doctor. Shake the bottle well before each use. The correct dose and duration will depend on your child’s age, body weight, and health condition. Always follow the instructions provided by your healthcare professional.

    Q: What are the possible side effects of Ascoril LS Expectorant?

    A: Some patients may experience mild side effects such as dizziness, drowsiness, headache, nausea, or vomiting. If any side effects become severe or persistent, consult your doctor promptly.

    Q: Can Ascoril LS Expectorant be used during pregnancy?

    A: Ascoril LS Expectorant should only be used during pregnancy if a doctor determines that the potential benefit outweighs any possible risk to the baby. Always consult a healthcare professional before use.

    Q: What precautions should be taken while using Ascoril LS Expectorant?

    A: Use Ascoril LS Expectorant with caution if you have kidney or liver problems, acute severe asthma, high blood pressure, uncontrolled diabetes, hyperthyroidism, seizures, gastric ulcers, or any condition affecting mucus production or clearance. Always follow your doctor’s guidance in such cases.

    Q: Who should avoid Ascoril LS Expectorant?

    A: Avoid Ascoril LS Expectorant if you are allergic to Ambroxol, Guaifenesin, or Levosalbutamol. It is also not recommended for people with heart disease, risk of heart attack, thyrotoxicosis, hereditary fructose intolerance, or porphyria. Always consult your doctor before use if any of these conditions apply.

    Q: Can Ascoril LS Expectorant cause nausea or vomiting?

    A: Some patients may experience mild nausea or vomiting due to the medicine’s bitter taste. To make it easier to take, the syrup can be mixed with fruit juice before consumption.

    Q: Does Ascoril LS Expectorant cause weight changes?

    A: Ascoril LS Expectorant is not known to cause changes in body weight. Most patients do not experience weight gain or loss as a result of taking this medicine. If you notice any unusual changes in weight while using it, discuss them with your healthcare professional for proper evaluation.

    Q: Can I take other medicines along with Ascoril LS Expectorant?

    A: Before taking Ascoril LS Expectorant, inform your doctor about any other medicines you are taking, including prescription drugs, over-the-counter medicines, or herbal supplements. Certain combinations may interact, so medical guidance is important.

    References

    1. KD. Tripathi. Drugs for cough and bronchial asthma. Essentials of Medical Pharmacology. Eighth Edition. 2019. Page – 238, 240.

    2. Zaitsev AA, Leshchenko IV, Esaulova NA, Viktorova IA. [Evaluation of the efficacy and safety of a combination drug containing ambroxol, guaifenesin, and levosalbutamol versus a fixed-dose combination of bromhexine/guaifenesin/salbutamol in the treatment of productive cough in adult patients with acute bronchitis. [Accessed on 6th February 2026] 

    3. Centaur Pharma. Ambroxol+Guaiphenesin+Levosalbutamol. [Revised in January 2021] [Accessed on 6th February 2026] 

    4. Cachet Pharmaceuticals Pvt. Ltd. [Revised on July 01, 2023] [Accessed on 6th February 2026]

    Useful Diagnostic Tests

    Author Details

    Written By Srilekha. R - B.Pharm
    Reviewed For Accuracy By Dr. Rajnikant - MBBS, MD (Physiology)
    Last updated on 19 Nov 2024 | 12:17 PM(IST)
    Lab updated