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Introduction About ARKAMIN 100MCG TABLET
What is Arkamin 100mcg Tablet?
Arkamin 100mcg is primarily used for the management of hypertension (high blood pressure). It helps lower blood pressure by relaxing blood vessels.
Arkamin 100mcg helps in reducing high blood pressure, manages stroke and heart-related complications and improves overall cardiovascular health.
Take Arkamin Tablet as prescribed by your doctor. Usually, it is taken once or twice daily with or without food.
Before taking Arkamin Tablet, inform your doctor if you have Raynaud’s phenomenon, depression, constipation, altered sensation, diabetes, liver, and/or kidney problems.
The most common side effects of taking Arkamin Tablet are dizziness, dry mouth, fatigue or headache. Consult your doctor if any of the above side effects worsen or persists for a longer duration.
Key Composition
- The primary active ingredient in Arkamin 100mcg Tablet is Clonidine hydrochloride at a strength of 100 mcg per tablet
Uses Of ARKAMIN 100MCG TABLET
- Used to manage hypertension (high blood pressure)
Benefits of ARKAMIN 100MCG TABLET
1. Reduces high blood pressure:
- Arkamin lowers blood pressure by relaxing blood vessels and reducing the heart's workload
- It helps to reduce sudden spikes in blood pressure, ensuring stable circulation
2. Manages stroke and heart-related complications:
- By controlling hypertension, Arkamin reduces the risk of serious conditions like stroke, heart attack, and heart failure
- It lowers excessive stress on the heart and arteries reducing long-term damage
3. Improves overall cardiovascular health:
- Regular use helps maintain healthy blood flow, reducing the chances of artery damage
- Supports better oxygen delivery to vital organs, improving overall circulatory function
How ARKAMIN 100MCG TABLET Works
1. Acts on the Brain:
- Clonidine stimulates alpha-2 adrenergic receptors in the brainstem
- This reduces the release of norepinephrine (Stress hormone), which normally increases blood pressure
2. Lowers sympathetic nervous system activity:
- Arkamin Tablet relaxes blood vessels, making it easier for the heart to pump blood
- Heart rate decreases, leading to lower blood pressure
3. Reduces peripheral resistance:
- Arteries and veins dilate, improving blood flow
- This manages excessive strain on the heart and reduces the risk of complications like stroke and heart failure
How to use ARKAMIN 100MCG TABLET
Arkamin 100mcg Tablet is a prescription medicine which needs to be taken under medical supervision. Always consult your doctor or pharmacist if you have any questions or concerns about taking this medication.
How to take Arkamin 100mcg Tablet:
- Take Arkamin 100mcg Tablet as prescribed by your doctor
- Usually Arkamin 100mcg Tablet is taken once or twice daily with or without food
- Swallow the medicine with a glass of water. Do not crush or chew the medicine
Recommended dosage for Arkamin 100mcg:
- Starting dose: 100 mcg (0.1 mg) twice daily (morning and bedtime)
- Maintenance dose: 200-600 mcg per day, divided into two or three doses
- Maximum dose: 2.4 mg per day (in severe cases, under strict medical supervision)
- Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition
What if I forgot to take ARKAMIN 100MCG TABLET
Missed dose of Arkamin 100mcg Tablet - What to do?
- Take Arkamin 100mcg as soon as you remember
- Skip the missed dose if it is almost time for the next dose
- Do not double the dose to make up for the missed one
- Suddenly stopping Clonidine can cause rebound high blood pressure, anxiety, or rapid heartbeat
Side Effects Of ARKAMIN 100MCG TABLET
Common side effects include:
- dizziness
- dry mouth
- fatigue
- headache
When to consult a doctor?
- signs of pseudo-obstruction of the large bowel such as colicky pain, vomiting and constipation
How To Manage Side Effects

Dizziness Or Drowsiness
- If you feel dizzy, find a safe place to sit or lie down immediately to avoid falls
- Dehydration can worsen dizziness, so drink plenty of water throughout the day
- When moving from a seated or lying position, do so slowly to help your body adjust

Dry Mouth
- Drink plenty of water throughout the day
- Chewing sugar-free gum or sucking on sugar-free hard candies stimulates saliva production
- Over-the-counter artificial saliva sprays or oral moisturizers can provide relief

Headache
- Drink plenty of water throughout the day
- Maintain balanced meals with proteins, healthy fats, and fiber
- Aim for 7-8 hours of restful sleep

Tiredness
- Eat nutrient-rich foods like fruits, vegetables, whole grains, and lean proteins to sustain energy levels
- Aim for 7–9 hours of quality sleep per night to help your body recover
- Fatigue may indicate low blood pressure. Regularly check your BP levels and report any significant drops to your doctor
Warning & Precautions

Pregnancy
Monitoring requiredArkamin 100mcg Tablet is an approved FDA Pregnancy C category, clonidine has shown adverse effects in animal studies, but adequate human studies are limited. Some clinical reports suggest that Clonidine may cross the placenta, leading to transient changes in fetal heart rate and neonatal drowsiness, bradycardia and hypotension after birth. Hence use only if benefits outweigh risks, and under strict medical supervision.

Breastfeeding
ContraindicatedClonidine passes into breast milk and may affect the nursing infant. Some reported effects on infants include drowsiness & sedation, weak sucking reflex (may impact feeding) and lower blood pressure and heart rate. Hence it is not recommended due to potential infant effects. If needed, monitor the baby closely for signs of sedation or feeding difficulties.

Driving and Using Machines
Use with CautionDo not drive or operate any machines if you feel drowsy, dizzy or have some disturbances of vision after taking Arkamin 100mcg.

Alcohol
Consult your doctorAvoid consumption of alcohol while taking Arkamin 100mcg as it may alter the effect of the medicine.

Kidney
Monitoring requiredArkamin Tablet is eliminated through the kidneys, so impaired kidney function can cause drug buildup, leading to excessive drowsiness, low blood pressure, or slow heart rate. Periodic creatinine and kidney function tests (eGFR) should be done to assess drug clearance.

Liver
Monitoring requiredLiver impairment may slow down Arkamin metabolism, increasing side effects like drowsiness, dizziness, and confusion. Liver function tests (LFTs) should be conducted periodically. Clonidine clearance may be reduced, so dose adjustments may be required.

Allergy
ContraindicatedDo not take Arkamin Tablet if you are allergic to Clonidine or any of the other ingredients of this medicine.

Heart Disease
ContraindicatedArkamin Tablet is not recommended for use in patients with problems such as heart failure, slow irregular heart rate.

Use In Pediatrics
ContraindicatedArkamin 100mcg Tablet is not recommended for use in children and adolescents (aged below 18 years).

Use In Geriatrics
Use with CautionArkamin 100mcg Tablet should be used with caution in elderly patients (aged above 60 years).
Other Warnings for ARKAMIN 100MCG TABLET
Before taking Arkamin 100mcg Tablet, inform your doctor if you:
- have signs of Raynaud’s phenomenon
- have or ever had depression
- have constipation
- have altered sensation
- low blood pressure while standing up
- have intolerance or difficulty to digest certain sugars (such as lactose)
- have diabetes
- have signs of phaeochromocytoma (rare tumor of the adrenal gland)
- stroke or transient ischeamic attack (TIA)
Who should not take [GBNKEYWORD
Arkamin 100mcg Tablet is not recommended for use if you:
- have rare hereditary condition of galactose intolerance
Diet and Lifestyle Advice
Food interactions with Arkamin 100mcg Tablet:
- Caffeinated drinks (coffee, tea, energy drinks, soda) - Limit caffeine intake to avoid fluctuations in blood pressure
- High-sodium foods - Follow a low-sodium diet to maximize Arkamin Tablet benefits
- High-fat meals - Opt for heart-healthy fats like nuts, seeds, olive oil, and avocados
- Grapefruit & citrus fruits
- Iron-rich foods & supplements - take clonidine at least 2 hours apart from iron supplements
Drug - Drug interaction
Medications to avoid with Arkamin 100mcg:
1. Blood pressure & heart medications:
- Beta-blockers - Metoprolol, Propranolol, Atenolol
- Calcium channel blockers - Amlodipine, Diltiazem, Verapamil
- Diuretics - Furosemide, Hydrochlorothiazide, Spironolactone
2. Central Nervous System (CNS) Depressants:
- Sedatives & Sleeping Pills - Diazepam, Alprazolam, Zolpidem, Clonazepam
- Opioid painkillers - Morphine, Tramadol, Oxycodone, Codeine
- Antidepressants - Amitriptyline, Sertraline, Fluoxetine, Paroxetine, Mirtazapine
- Antipsychotics - Risperidone, Quetiapine, Olanzapine
3. Stimulants & ADHD medications:
- Methylphenidate, Amphetamines, Modafinil
- Other ADHD Medications (e.g., Atomoxetine, Guanfacine)
4. Blood thinners & Anticoagulants:
- Warfarin, Aspirin, Clopidogrel, Heparin, Dabigatran
Drug - Food interaction
Food interactions with Arkamin 100mcg Tablet:
- Caffeinated drinks (coffee, tea, energy drinks, soda) - Limit caffeine intake to avoid fluctuations in blood pressure
- High-sodium foods - Follow a low-sodium diet to maximize Arkamin Tablet benefits
- High-fat meals - Opt for heart-healthy fats like nuts, seeds, olive oil, and avocados
- Grapefruit & citrus fruits
- Iron-rich foods & supplements - take clonidine at least 2 hours apart from iron supplements
Synopsis
Drug | : | Clonidine |
Pharmacological Category | : | Central alpha agonists |
Therapeutic Indication | : | Hypertension |
Dosage Forms | : | Tablet, Injection |
More Information
Hypertension (High Blood Pressure):
Hypertension, or high blood pressure, is a chronic condition where the force of blood against the artery walls remains too high, increasing the risk of heart disease, stroke, and kidney damage.
1. Causes of Hypertension:
- Primary (Essential) Hypertension – No specific cause, but linked to lifestyle and genetics
- Secondary Hypertension – Caused by an underlying condition like kidney disease, thyroid issues, or certain medications
Common risk factors:
- Unhealthy Diet: High salt, processed foods, or excessive alcohol intake
- Lack of Physical Activity: Leads to weight gain and poor circulation
- Obesity: Extra weight increases strain on the heart
- Smoking & Alcohol: Damages blood vessels and raises BP
- Stress: Triggers hormones that temporarily spike BP
- Genetics: Family history of hypertension increases risk
- Medical Conditions: Diabetes, kidney disease, thyroid disorders
2. Symptoms of high blood pressure:
- Persistent headaches
- dizziness or fainting
- blurred vision
- shortness of breath
- chest pain (severe cases)
- nosebleeds (rare, but possible in extreme bp spikes)
3. Management options for hypertension:
- Lifestyle modifications (first-line approach)
- medications for Hypertension
4. Complications of uncontrolled hypertension:
- Heart disease & stroke – Increased strain on the heart leads to heart attack, heart failure, or stroke
- Kidney damage – High BP weakens kidney function, leading to chronic kidney disease (CKD)
- Vision loss – Hypertension can damage the retinal blood vessels, causing hypertensive retinopathy
- Cognitive decline – Long-term hypertension increases the risk of dementia and memory loss
Arkamin 100mcg and weight gain concerns:
- Slowed Metabolism
- Increased Appetite
- Water Retention
- Fatigue & Reduced Activity
FAQs About ARKAMIN 100MCG TABLET
Q: What is Arkamin 100mcg Tablet used for?
A: Arkamin 100mcg is primarily used for the management of hypertension (high blood pressure). It helps lower blood pressure by relaxing blood vessels.
Q: How does Arkamin 100mcg work?
A: Arkamin 100mcg Tablet is an alpha-2 adrenergic agonist that works by affecting nerve signals in the brain to lower blood pressure.
Q: Can Arkamin 100mcg Tablet be used in children?
A: Arkamin 100mcg Tablet is primarily prescribed for hypertension (high blood pressure) in adults, but it may sometimes be used in children for specific conditions under medical supervision.
Q: Is Arkamin 100mcg habit-forming?
A: No, Arkamin 100mcg Tablet is not considered habit-forming in the traditional sense. However, it can cause physical dependence if used for a long time.
Q: Is Arkamin 100mcg Tablet safe for long-term use?
A: Yes. Arkamin 100mcg should be used under medical supervision. Long-term use should be monitored by a doctor.
Q: Can Arkamin 100mcg be taken with other blood pressure medications?
A: Consult your doctor before combining Arkamin 100mcg with other medications.
Q: Does Arkamin 100mcg cause drowsiness?
A: Yes, Arkamin 100mcg Tablet can cause drowsiness as a common side effect.
Q: Is Arkamin 100mcg safe during pregnancy?
A: Arkamin 100mcg Tablet should be used during pregnancy only if prescribed by a doctor. While it may be used in some cases, there are potential risks to consider.
Q: Can Arkamin 100mcg be taken if I have an intolerance to sugars?
A: It is advisable to consult your doctor before taking Arkamin 100mcg if you have intolerance to certain sugars (such as lactose). It is generally not recommended for use if you have rare hereditary condition of galactose intolerance.
Q: What are the common side effects of Arkamin 100mcg?
A: The most common side effects of taking Arkamin Tablet are dizziness, dry mouth, fatigue or headache.
References
1. K.D. Tripathi. Anti-Hypertensive Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page:565.
2. Abbas Alshami, Carlos Romero, America Avila, and Joseph Varon. Management of hypertensive crises in the elderly. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central. July 2018. [Accessed on 20th March 2025]
3. Clinect Pty Ltd. MEDSAFE (New Zealand Medicines and Medical Devices Safety Authority). [Revised in January 2021] [Accessed on 20th March 2025]
4. Glenwood GmbH. Health Products Regulatory Authority (HPRA). [Revised in December 2021] [Accessed on 20th March 2025]