This test checks for special proteins called IgG antibodies that your body may make against a substance called cardiolipin, which is found in the walls of your cells and blood platelets. These antibodies can sometimes cause problems with blood clotting. The test helps doctors find out if you have a higher risk of forming blood clots, having repeated miscarriages, or certain autoimmune conditions like antiphospholipid syndrome (APS). It is a simple blood test and does not require fasting.

Why is it Important?

Detects Blood Clotting Risk
This test helps find out if you are at a higher risk for dangerous blood clots, which can block blood flow in your legs, lungs, or other parts of your body.
Helps Diagnose Antiphospholipid Syndrome (APS)
APS is an autoimmune disorder that can cause repeated blood clots or miscarriages. This test is one of the main ways doctors check for APS.
Guides Pregnancy Care
If you have had repeated miscarriages, especially in the second or third trimester, this test can help doctors find out if antibodies are the cause and plan your care during pregnancy.
Monitors Autoimmune Conditions
People with diseases like lupus may need this test to check if they have a higher risk of clotting problems. It helps doctors adjust treatment to keep you safe.
Assists in Finding the Cause of Symptoms
If you have unexplained symptoms like swelling, pain in your legs, or sudden shortness of breath, this test can help doctors find out if blood clots are the reason.

When Should I Get This Test?

If you have had unexplained blood clots in your veins or arteries (like DVT or pulmonary embolism)
If you have had two or more unexplained miscarriages, especially after the first trimester
If you have symptoms of an autoimmune disease (like lupus)
If your doctor finds you have a low platelet count or unusual blood clotting times
If you are being checked for antiphospholipid syndrome (APS) or other clotting disorders

Interpretation of Test Results

Understanding what your results might mean is helpful, but always discuss them with a doctor for a proper diagnosis.

Result Type	What it Means
Normal	No or very low IgG antibodies; low risk for related clotting problems
Borderline	Slightly higher than normal; may need repeat testing or more checks
Abnormal/High	High levels of IgG antibodies; higher risk for blood clots or APS

(Note: Specific normal ranges can vary slightly between labs and depending on individual factors. Always refer to the ranges provided on your report and consult your doctor.)

Additional Information

This test alone cannot diagnose a disease; your doctor will use it along with your symptoms and other tests.
Sometimes, infections or certain medicines can cause a temporary rise in these antibodies.
If your results are abnormal, your doctor may repeat the test after 12 weeks to confirm the diagnosis.

Test Requirements

Sample Type: Blood sample, usually taken from a vein in your arm.
Preparation: No fasting is needed for this test.
Precautions: Tell your doctor about any medicines you are taking, as some can affect the results.

FAQs

Do I need to fast before the Anti Cardiolipin IgG Antibody Test?
No, fasting is not required for this blood test. You can eat and drink as usual before your sample is taken.
What does a high result mean for my health?
A high level of IgG antibodies against cardiolipin may mean you have a higher risk for blood clots or a condition called antiphospholipid syndrome (APS). Your doctor will explain what this means for you and may order more tests.
Can this test be done during pregnancy?
Yes, this test is safe during pregnancy. It is often recommended if you have had repeated miscarriages or other pregnancy problems, as it can help doctors plan your care.
What should I do if my results are abnormal?
If your results are high or abnormal, talk to your doctor. They may repeat the test after 12 weeks and may check for other related antibodies. Never start or stop any medicine without your doctor’s advice.
Can an infection or medicine affect my test results?
Yes, sometimes infections or certain medicines can cause a temporary rise in these antibodies. That’s why doctors may repeat the test later to confirm the results.

For more information, see Netmeds Health Library: Deep Vein Thrombosis: Causes, Symptoms And Treatment

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