Ampilox C Drops 10ml

Introduction About AMPILOX C DROPS

AMPILOX C DROPS is a combination of Ampicillin and Cloxacillin which belongs to the group of medicines called Penicillin Antibiotics. It is used to manage respiratory tract infections like bronchopneumonia, acute exacerbations of chronic bronchitis, post-operative wound infections, post-operative lung infections, puerperal fever and other infections such as septicaemia, bone infections like osteomyelitis, ear, nose and throat infections. It is also indicated for the prophylaxis or management of bacterial infections in premature babies or neonates.

Before taking AMPILOX C DROPS inform your doctor if you have liver or kidney disease. There is no proper information on the use of AMPILOX C DROPS during pregnancy and breastfeeding, and therefore consult your doctor before taking.

AMPILOX C DROPS should be used with caution in children. Contact your doctor before taking.

AMPILOX C DROPS should be used with caution in elderly patients aged 65 years and above. Contact your doctor before taking.

The most common side effects of taking AMPILOX C DROPS are nausea, vomiting, diarrhea, skin rash, urticaria and pruritus. Contact your doctor if any of the above side effects worsen.

Uses Of AMPILOX C DROPS

It is used to manage:

• respiratory tract infections like bronchopneumonia, acute exacerbations of chronic bronchitis
• post-operative wound infections
• post-operative lung infections
• puerperal fever
• septicaemia
• bone infections like osteomyelitis
• ear, nose and throat infections

How AMPILOX C DROPS Works

AMPILOX C DROPS is a combination of Ampicillin and cloxacillin where ampicillin has a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It acts through the inhibition of cell wall mucopeptide biosynthesis during the stage of active multiplication. Cloxacillin manages bacteria from reproducing, which allows your body to fight only the existing bacteria.

How to use AMPILOX C DROPS

Take this medicine as advised by your physician. Shake well before use. Measure it with a dropper and take it as directed. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Side Effects Of AMPILOX C DROPS

How To Manage Side Effects

Nausea or Vomiting:

Take this medicine with, or just after meals. Stick to simple meals. Avoid eating oily or spicy foods.

Diarrhoea:

Drink lots of fluids, such as water or fruit juices to keep you hydrated. Do not take any medicine on your own for managing diarrhea. Contact your doctor if the symptom did not improve.

Skin rash:

Avoid hot showers because hot water can further irritate your skin. Do not scratch the affected area. Use protective clothing when going outdoors. Regularly moisturize your skin. Contact your doctor if the symptoms did not resolve.

Warning & Precautions

Pregnancy

There is no proper information on the use of AMPILOX C DROPS during pregnancy and therefore consult your doctor before taking.

Breastfeeding

There is no proper information on the use of AMPILOX C DROPS during breast feeding and therefore consult your doctor before taking.

Driving and Using Machines

AMPILOX C DROPS has no adverse effects on the ability to drive or operate machinery. Consult your doctor before taking.

Kidney

AMPILOX C DROPS should be used with caution in patients with kidney disease. Contact your doctor before taking.

Liver

AMPILOX C DROPS should be used with caution in patients with liver disease. Consult your doctor before taking.

Allergy

Do not take AMPILOX C DROPS if you are allergic to Ampicillin, Cloxacillin or to beta lactam antibiotics (Ex. penicillins, cephalosporins) or to other ingredients of this medicine.

Interactions

A. Drug-Drug interactions:

Inform your physician, if you are taking,

• medicines which inhibit the bacteria growth (Ex. chloramphenicol, erythromycin, sulphonamides and tetracyclines)
• medicines used to manage gout (Ex. probenecid, allopurinol)
• acetylsalicylic acid (medicine used to manage blood clots)
• medicines used to manage pregnancy (Ex. oral contraceptives)

Overdosage:

If you or anyone else accidentally took too much of this medicine, consult your doctor immediately. Symptoms of overdose are gastrointestinal effects such as nausea, vomiting and diarrhea.

Synopsis

More Information

• Keep out of reach of children
• Store AMPILOX C DROPS at 25°C

FAQs About AMPILOX C DROPS

Can I use AMPILOX C DROPS in pregnancy?

There is no proper information on the use of this medicine in pregnancy. Contact your doctor before taking.

Can I use AMPILOX C DROPS for long time?

No. Using AMPILOX C DROPS for a longer time may result in overgrowth of non-susceptible organisms, gastrointestinal infections like severe diarrhea with bleeding, abdominal cramps. Long term or misuse of AMPILOX C DROPS results in resistance of the bacteria and makes the medicine less effective. Therefore, take this medicine as advised by your physician.

Can I take other medicines at the same time while using AMPILOX C DROPS?

No. AMPILOX C DROPS interacts with other medicines. Tell your doctor if you or your children are taking or have recently taken any other medicines, including medicines obtained with or without a prescription, vitamin supplement or herbal products.

What are the side effects of taking AMPILOX C DROPS?

The most common side effects of taking AMPILOX C DROPS are nausea, vomiting, diarrhea, skin rash, urticaria and pruritus. Contact your doctor if any of the symptoms worsen.

Can I stop taking AMPILOX C DROPS when I feel better?

No, do not stop taking this medicine and complete the full course of management even if you feel better. Your symptoms may improve before the infection is completely managed.

References

1. KD. Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page-722 to 723.

2. B. S. Jadhav, Dilip Pawar, Vijay Vare, Kunal Sonawane, Amol Shinde. Mechanism of ampicillin and cloxacillin. International Journal of Medicine. February 2021. [Accessed on 27th May 2022] https://www.researchgate.net/publication/349734144_A_review_of_synergistic_fixed_dose_combination_of_Ampicillin_and_Cloxacillin_for_broad_spectrum_anti-bacterial_activity/link/603f901092851c077f14561e/download

3. MEDREICH LIMITED. Ampicillin and Cloxacillin. [Revised on August 2014] [Accessed on 27th May 2022] https://gskpro.com/content/dam/global/hcpportal/en_NG/PDF/Home/Products/Ampiclox_GA_03.pdf

Useful Diagnostic Tests

• Complete blood count
• Peripheral smear examination

Author Details

Written By Dr. Janet.C - Pharm.D

Reviewed For Accuracy By Dr. Salem Gill - MBBS

Last updated on 23 Nov 2022 | 11:46 PM(IST)