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Introduction About AMPILON INJECTION
AMPILON INJECTION contains Ampicillin which belongs to the group of medicines called Antibiotics. It is used to manage bacterial infections of the ear, nose, throat, respiratory tract (bronchus, lungs), urinary tract, genital tract, stomach, blood, brain and skin or soft tissues.
It can also be used to manage typhoid fever, meningitis (inflammation of the lining of the brain), peritonitis (inflammation of the lining of the stomach) and endocarditis (inflammation of the lining of the heart and its valves).
AMPILON INJECTION should be used under medical supervision. Do not stop receiving AMPILON INJECTION even if you feel better during the midway of the therapy. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control.
During therapy with AMPILON INJECTION, your doctor will periodically monitor your health condition through several blood tests/urine tests to access the improvement in your condition and to reduce the risk of unwanted side effects. AMPILON INJECTION is suitable for use in adults and in children (aged 10 years or older; weighing 20 kg or more).
Before receiving AMPILON INJECTION inform your doctor if you have any kidney problems. You must also inform your doctor if you have blood cancer or any viral infections (such as cytomegalovirus infection) as a precaution.
AMPILON INJECTION should be used in pregnant or breastfeeding women only if considered necessary by the physician. The most common side effects of receiving AMPILON INJECTION are nausea, vomiting and diarrhea. Inform your doctor if they trouble you.
Uses Of AMPILON INJECTION
It is used to manage various bacterial infections such as:
- Ear infections (Ex. otitis media)
- Nose or throat infections
- Respiratory tract infections (Ex. bronchitis and pneumonia)
- Urinary tract infections (Ex. cystitis and kidney infections)
- Genital tract infections (Ex. gonorrhoea)
- Stomach infections (Ex. peritonitis)
- Blood infections (Ex. sepsis)
- Skin or soft tissue infections (Ex. acne)
- Meningitis (inflammation of the protective layer surrounding the brain)
- Endocarditis (inflammation of the protective layer surrounding the heart)
- Typhoid fever
How AMPILON INJECTION Works
AMPILON INJECTION is a bactericidal agent. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis that is essential for the bacterial cell to survive. This action destroys the susceptible bacteria, manage their further growth and multiplication and reduce the severity of the infection.
How to use AMPILON INJECTION
AMPILON INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously) or into the muscles (intramuscularly).
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
Do not miss a dose or stop receiving AMPILON INJECTION without consulting your doctor as it may worsen your condition.
Side Effects Of AMPILON INJECTION
Common
- diarrhoea
- nausea, vomiting
Rare
Stop receiving AMPILON INJECTION and contact your doctor immediately if you experience any of the following side effects:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- stomach pain with uncontrollable watery diarrhoea, feeling weak and fever
- severe skin reactions (such as widespread skin rash with blistering and peeling of skin around the mouth, face and genitals)
- signs of liver problems (such as yellowing of skin and whites of the eye, pale faeces, dark urine, persistent nausea, loss of appetite, unusual tiredness)
- unusual bleeding or bruising
- fever, sore throat, mouth ulcers, repeated infections
- signs of kidney problems (such as passing low urine, passing urine at night, tiredness, breathlessness, pale skin, fever, skin rash, nausea, pains)
How To Manage Side Effects
Nausea or vomiting:
Take AMPILON INJECTION with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Please consult your doctor immediately if you experience severe nausea and vomiting.
Diarrhoea:
Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens, contact your doctor immediately.
Warning & Precautions
Pregnancy
AMPILON INJECTION should be used with caution in pregnant women. Therefore, consult your doctor before receiving it.
Breastfeeding
AMPILON INJECTION should be used with caution in breastfeeding women as it may pass through the breast milk. Therefore, consult your doctor before receiving it.
Driving and Using Machines
AMPILON INJECTION is unlikely to affect your ability to drive or operate any heavy tools or machines.
Kidney
AMPILON INJECTION should be used with caution in patients suffering from kidney problems. Therefore, consult your doctor before receiving it.
Allergy
Do not receive AMPILON INJECTION if you are allergic to Ampicillin, or to any other beta lactam antibiotics (such as amoxicillin) or cephalosporin antibiotics (such as cefixime).
Others
Before receiving AMPILON INJECTION, inform your doctor if you:
- have glandular fever
- have lymphatic leukaemia (cancer or blood or bone marrow)
- have cytomegalovirus (CMV) infection
Use in pediatrics:
AMPILON INJECTION can be used in children and adolescents (aged 10 years or older; weighing 20 kg or more) if prescribed by the physician. However, consult your doctor for advice.
Use in geriatrics:
AMPILON INJECTION should be used with caution in the elderly patients. Therefore, consult your doctor for advice before receiving it.
Interactions
A. Drug-Drug interactions:
Before receiving AMPILON INJECTION, inform your doctor if you are taking any of the following medicine:
- oral contraceptives (birth control pills) Ex. drospirenone, ethinyl Estradiol
- allopurinol, sulfinpyrazone or probenecid (medicines used to manage gout)
- other antibiotics (used to manage bacterial infections) such as tetracycline, erythromycin, and chloramphenicol
- anticoagulants such as warfarin or phenindione
Overdosage:
AMPILON INJECTION will be administered to you only by a doctor or a nurse in a hospital, and so it is unlikely to receive an overdose. Symptoms of overdosage might include gastrointestinal effects such as nausea, vomiting and diarrhoea.
Synopsis
| Drug | : | Ampicillin |
| Pharmacological Category | : | Penicillin Antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Injection, Drops, Dry Syrup |
More Information
- Keep AMPILON INJECTION out of reach of children
- Store AMPILON INJECTION at room temperature
FAQs About AMPILON INJECTION
What is the use of AMPILON INJECTION?
AMPILON INJECTION is used to manage bacterial infections of the ear, respiratory tract (bronchus, lungs), urinary tract, genital tract, stomach, blood, brain or skin and soft tissues. It can also be used to manage typhoid fever, meningitis, peritonitis and endocarditis.
How AMPILON INJECTION works in my body?
AMPILON INJECTION is a bactericidal agent. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis that is essential for the bacterial cell to survive. This action destroys the susceptible bacteria, manage their further growth and multiplication and reduce the severity of the infection.
Can AMPILON INJECTION be used in patients with kidney problems?
AMPILON INJECTION should be used with caution in patients with kidney problems. Therefore, consult your doctor before receiving it.
How AMPILON INJECTION is administered?
AMPILON INJECTION will be given to you only by a doctor or a nurse into the vein (intravenously) or into the muscles (intramuscularly).
For how long should I take AMPILON INJECTION?
Take AMPILON INJECTION for the stipulated duration as prescribed by your doctor. Do not skip the medicine or stop receiving it on your own as it may cause the infection to become severe.
Can AMPILON INJECTION be given to pregnant women?
AMPILON INJECTION should be used with caution in pregnant women. Therefore, consult your doctor before receiving it.
What precautions should I follow while receiving AMPILON INJECTION?
Before receiving AMPILON INJECTION inform your doctor if you have any kidney problems. You must also inform your doctor if you have blood cancer, any viral infections (such as cytomegalovirus infection) or if you are pregnant or breastfeeding as a precaution. Regularly visit your doctor for check-up and perform all medical tests recommended by your doctor without fail. Take AMPILON INJECTION for the stipulated duration recommended by your doctor to achieve better results. Failing to do so may cause the symptom to re-occur.
What are the common side effects of receiving AMPILON INJECTION?
The most common side effects of receiving AMPILON INJECTION are nausea, vomiting and diarrhea. Inform your doctor if they trouble you.
Can I stop receiving AMPILON INJECTION once my symptoms subside?
Do not stop receiving AMPILON INJECTION once your symptoms subside. It is important to take the full course of AMPILON INJECTION to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.
Can the use of AMPILON INJECTION cause diarrhea?
AMPILON INJECTION may cause diarrhea in some individuals. If you experience diarrhea, drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens contact your doctor immediately.
What kind of infections that AMPILON INJECTION can manage?
AMPILON INJECTION is an antibiotic. It is used to manage infections caused by bacteria. It kills harmful bacteria by binding to the bacterial cell and interfering with cell wall synthesis. It can manage bacterial infections of the ear, nose, throat, respiratory tract, urinary tract, genital tract, stomach, brain, blood and skin or soft tissues.
Who should not take AMPILON INJECTION?
AMPILON INJECTION is not recommended for use in patients allergic to penicillin antibiotics (such as amoxicillin). It should be used with caution in patients with kidney problems and in children. Inform your doctor if you are pregnant or planning to become pregnant or breastfeeding before receiving AMPILON INJECTION.
Is AMPILON INJECTION a steroid?
No. AMPILON INJECTION is an antibiotic and not a steroid medicine.
Can AMPILON INJECTION manage viral infections?
No. AMPILON INJECTION cannot manage viral infections. It manages only bacterial infections of upper respiratory tract, urinary tract, and skin infections. It acts by killing the susceptible bacteria which are responsible for causing infections, and therefore not effective against any viral infections.
Can AMPILON INJECTION cause fever?
AMPILON INJECTION may rarely cause a mild fever in some individuals. However, if you experience heavy fever accompanied with general weakness, sore throat or mouth and problems in passing urine consult your doctor immediately.
References
1. KD. Tripathi. Beta-Lactam Antibiotics. Essentials of medical pharmacology. Seventh edition. 2013. Page – 722.
2. Basil V. Peechakara; Hajira Basit; Mohit Gupta. Ampicillin. NCBI; US National Library of Medicine, National Institute of Health. 5 Nov 2021. [Accessed on 9th November 2022] https://www.ncbi.nlm.nih.gov/books/NBK519569/
3. Keith Kleinman MD. Ampicillin. Sciece direct. [Accessed on 9th November 2022] https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/ampicillin
4. Laboratorio Reig Jofre, S.A; Electronic Medicines Compendium (EMC) [Revised in September 2018] [Accessed on 9th November 2022] https://www.medicines.org.uk/emc/files/pil.12892.pdf
5. G.C. Hanford. (FDA). [Revised in October 2017]. [Accessed on 9th November 2022] https://www.fda.gov/media/127633/download
6. Pfizer Labs. (MFG). [Revised in September 2010] [Accessed on 9th November 2022] https://cdn.pfizer.com/pfizercom/products/uspi_ampicillin_10g_bulk.pdf
Useful Diagnostic Tests
- Complete Blood Count
- Peripheral Smear Examination
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