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INTRODUCTION ABOUT AMINOWEL INFUSION
AMINOWEL INFUSION contains Amino acid which are naturally occurring physiological compounds. It is used for management of protein depletion in patients requiring parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or not recommended. AMINOWEL INFUSION can be used to manage negative nitrogen balance in patients.
AMINOWEL INFUSION can also be used to manage hepatic encephalopathy in patients with liver scarring or inflammation.
Your doctor might monitor your fluid an electrolyte status and various other functions throughout your management.
AMINOWEL INFUSION is not recommended for use in patients with amino acid metabolism problems since birth, pulmonary edema, or excess acid in blood due to low cardiac output. Before receiving AMINOWEL INFUSION, inform your doctor if you have diabetes, kidney, heart, or liver disease.
AMINOWEL INFUSION should be used in pregnant and breastfeeding women only if considered clearly necessary. AMINOWEL INFUSION is not recommended for use in children and should be used with caution in elderly patients, therefore consult your doctor before receiving it.
The most common side effects of receiving AMINOWEL INFUSION are generalized flushing, fever, nausea, and local injection site reactions. Contact your doctor if any of the symptoms worsen.
USES OF AMINOWEL INFUSION
Prevents and manages,
- protein depletion in patients requiring parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or not recommended
Manages,
- manage negative nitrogen balance
- manage hepatic encephalopathy in patients with liver scarring or inflammation
HOW AMINOWEL INFUSION WORKS
AMINOWEL INFUSION acts as a nutrition supplement by providing the structural units that make up proteins and other biomolecules or are oxidized to urea and carbon dioxide as an energy source.
DIRECTIONS FOR USE
AMINOWEL INFUSION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you according to your age, body weight and disease condition.
SIDE EFFECTS OF AMINOWEL INFUSION
COMMON
- generalized flushing
- fever
- nausea
- local injection site reactions
RARE
Stop receiving AMINOWEL INFUSION and contact your doctor immediately if you experience any of the following side effects:
- signs of pulmonary distress
- hypersensitivity reactions (low or high blood pressure, bluish discoloration of extremities, fast heartbeat, breathlessness, vomiting, nausea, hives, rash, itching, redness, excessive sweating, fever, chills)
- risk of infections and sepsis
- refeeding syndrome (shift in intracellular potassium, phosphorus, and magnesium levels)
- high blood sugar levels
- venous thrombophlebitis (pain, redness, tenderness, palpable veins)
- hepatobiliary disorders and Parenteral Nutrition Associated Liver Disease as seen in liver test abnormalities
- aluminum toxicity
- severely raised electrolyte levels, fluid overload
HOW TO MANAGE SIDE EFFECTS
Nausea:
Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
AMINOWEL INFUSION should be used in pregnant women only if considered clearly necessary. Consult your doctor before receiving it.
BREASTFEEDING
AMINOWEL INFUSION should be used in breastfeeding women only if considered clearly necessary. Consult your doctor before receiving it.
KIDNEY
AMINOWEL INFUSION is not recommended for use in patients who are unable to produce urine. AMINOWEL INFUSION should be used with caution in patients with history of renal disease or renal impairment. Consult your doctor before receiving it.
LIVER
AMINOWEL INFUSION is not recommended for use in patients with liver diseases such as hepatic coma. AMINOWEL INFUSION should be taken with caution in patients with severe liver disease. Consult your doctor before receiving it.
ALLERGY
Do not receive AMINOWEL INFUSION if you are allergic to Amino acid or any of the other ingredients of this medicine.
LUNGS
AMINOWEL INFUSION is not recommended for use in patients with lung diseases such as pulmonary edema. AMINOWEL INFUSION should be used with caution in patients with lung disease. Consult your doctor before receiving it.
HEART DISEASE
AMINOWEL INFUSION should be used with caution in patients with cardiac insufficiency or severe congestive heart failure. Consult your doctor before receiving it.
OTHERS
AMINOWEL INFUSION is not recommended for use if you have:
- amino acid metabolism problems since birth, due to risk of severe metabolic or neurologic complications
- acidosis (acid build-up)
- metabolic disorders with impaired nitrogen utilization
- azotemia (build-up of nitrogenous products in blood)
Before receiving AMINOWEL INFUSION, inform your doctor if you have:
- conditions involving edema with sodium retention
- high blood potassium levels or potassium retention
- diabetes or are pre-diabetic
Use in pediatrics:
AMINOWEL INFUSION is not recommended for use in children as safety and efficacy of the medicine has not been studies in them. Consult your doctor before receiving it.
Use in geriatrics:
AMINOWEL INFUSION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving it.
INTERACTIONS
A. Drug - Drug interactions:
Before receiving AMINOWEL INFUSION, inform your doctor if you are taking any of the following medicine:
- tetracycline (used to manage bacterial infections)
Overdosage:
AMINOWEL INFUSION will be administered to you only by a doctor or a nurse in a hospital, and so you are unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Amino acid |
| Pharmacological Category | : | Naturally occurring physiological compounds |
| Therapeutic Indication | : | Protein depletion |
| Dosage Forms | : | Injection, Infusion |
MORE INFORMATION
- Keep AMINOWEL INFUSION out of reach of children
- Store AMINOWEL INFUSION between 20-25°C
FAQs ABOUT AMINOWEL INFUSION
Can AMINOWEL INFUSION be taken in pregnancy?
AMINOWEL INFUSION should be used in pregnant women only if considered clearly necessary. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before receiving this medicine. Inform your doctor immediately if you become pregnant during management with AMINOWEL INFUSION.
Does AMINOWEL INFUSION help lose weight?
AMINOWEL INFUSION may help you lose weight, depending on whether you are deficient or not. It is a simple and effective solution and offers great benefits in achieving weight loss if you are deficient in a key amino acid required for the metabolic process. It can give your body the nutrition it needs so that you feel your best and can burn more calories. Consult your doctor before receiving it.
Can AMINOWEL INFUSION be stopped by my own?
Continue receiving AMINOWEL INFUSION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such case, contact your doctor right away.
Can AMINOWEL INFUSION be used in diabetic patients?
Administration of AMINOWEL INFUSION in diabetic patients or patients with impaired glucose tolerance may further increase blood sugar levels. Frequent blood-sugar level measurements should be performed on diabetic patients receiving this medicine.
What precautions do I need to follow while taking AMINOWEL INFUSION?
Patients receiving AMINOWEL INFUSION must inform their doctor about their pre-existing conditions like kidney, liver, or heart problems, diabetes, or amino acid metabolism problems since birth. Patients should also inform if they are pregnant, breast-feeding, or having any allergies. Consult your doctor if you experience anything different.
Can AMINOWEL INFUSION cause nausea?
Nausea is a common side effect of AMINOWEL INFUSION. If you feel nauseous, take regular sips of a cold drink, or have ginger or peppermint tea. Stick to simple meals and avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.
Can I take other medicines with AMINOWEL INFUSION?
Before receiving AMINOWEL INFUSION, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine, as these might interact with each other and cause serious side effects.
REFERENCES
1. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo. Care of the Hospitalized Patient. Harrison’s Manual of Medicine. 18th edition. Page- 50.
2. Liebau, F., Sundström, M., van Loon, L.J. et al. Short-term amino acid infusion improves protein balance in critically ill patients. Critical Care. BMC. December 2015. [Accessed on 16th July 2022] https://ccforum.biomedcentral.com/articles/10.1186/s13054-015-0844-6
3. Shi Y, Song H, Liu J, Lin J, Fang L. Comprehensive Evaluation of Clinical Application of Balanced Compound Amino Acid Injection. NIH National Library of Medicine, National Centre for biotechnology information. PubMed Central. June 2022. [Accessed on 16th July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203120/
4. Baxter Healthcare Corporation. Amino acid. [Revised in October 2020] [Accessed on 16th July 2022] https://www.baxterpi.com/pi-pdf/Travasol_PI.pdf
5. Hospira Healthcare Corporation. Amino acid. [Revised in April 2012] [Accessed on 16th July 2022] https://pdf.hres.ca/dpd_pm/00016324.PDF
6. La Renon Healthcare Pvt. Ltd. Amino acid. [Accessed on 16th July 2022] https://www.larenon.com/wp-content/uploads/2019/01/1.-Lamino-8.pdf
7 Innovative Pharmaceuticals. Amino acid. [Accessed on 16th July 2022] https://www.innovativepharma.in/product/aminozen-infusion/
USEFUL DIAGNOSTIC TESTS
- Total protein test
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