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INTRODUCTION ABOUT AMINOVEN 5% SOLUTION
AMINOVEN 5% SOLUTION contains Amino acid which are naturally occurring physiological compounds. It is used for management of protein depletion in patients requiring parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or not recommended. AMINOVEN 5% SOLUTION can be used to manage negative nitrogen balance in patients.
AMINOVEN 5% SOLUTION can also be used to manage hepatic encephalopathy in patients with liver scarring or inflammation.
Your doctor might monitor your fluid an electrolyte status and various other functions throughout your management.
AMINOVEN 5% SOLUTION is not recommended for use in patients with amino acid metabolism problems since birth, pulmonary edema, or excess acid in blood due to low cardiac output. Before receiving AMINOVEN 5% SOLUTION, inform your doctor if you have diabetes, kidney, heart, or liver disease.
AMINOVEN 5% SOLUTION should be used in pregnant and breastfeeding women only if considered clearly necessary. AMINOVEN 5% SOLUTION is not recommended for use in children and should be used with caution in elderly patients, therefore consult your doctor before receiving it.
The most common side effects of receiving AMINOVEN 5% SOLUTION are generalized flushing, fever, nausea, and local injection site reactions. Contact your doctor if any of the symptoms worsen.
USES OF AMINOVEN 5% SOLUTION
Prevents and manages,
- protein depletion in patients requiring parenteral nutrition when oral or enteral nutrition is not possible, insufficient, or not recommended
Manages,
- manage negative nitrogen balance
- manage hepatic encephalopathy in patients with liver scarring or inflammation
HOW AMINOVEN 5% SOLUTION WORKS
AMINOVEN 5% SOLUTION acts as a nutrition supplement by providing the structural units that make up proteins and other biomolecules or are oxidized to urea and carbon dioxide as an energy source.
DIRECTIONS FOR USE
AMINOVEN 5% SOLUTION will be given to you only by a doctor or a nurse into a vein as an intravenous infusion. Your doctor will decide the correct dose and duration for you according to your age, body weight and disease condition.
SIDE EFFECTS OF AMINOVEN 5% SOLUTION
COMMON
- generalized flushing
- fever
- nausea
- local injection site reactions
RARE
Stop receiving AMINOVEN 5% SOLUTION and contact your doctor immediately if you experience any of the following side effects:
- signs of pulmonary distress
- hypersensitivity reactions (low or high blood pressure, bluish discoloration of extremities, fast heartbeat, breathlessness, vomiting, nausea, hives, rash, itching, redness, excessive sweating, fever, chills)
- risk of infections and sepsis
- refeeding syndrome (shift in intracellular potassium, phosphorus, and magnesium levels)
- high blood sugar levels
- venous thrombophlebitis (pain, redness, tenderness, palpable veins)
- hepatobiliary disorders and Parenteral Nutrition Associated Liver Disease as seen in liver test abnormalities
- aluminum toxicity
- severely raised electrolyte levels, fluid overload
HOW TO MANAGE SIDE EFFECTS
Nausea:
Have ginger or peppermint tea. Stick to simple meals. Avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.
WARNING & PRECAUTIONS
PREGNANCY
AMINOVEN 5% SOLUTION should be used in pregnant women only if considered clearly necessary. Consult your doctor before receiving it.
BREASTFEEDING
AMINOVEN 5% SOLUTION should be used in breastfeeding women only if considered clearly necessary. Consult your doctor before receiving it.
KIDNEY
AMINOVEN 5% SOLUTION is not recommended for use in patients who are unable to produce urine. AMINOVEN 5% SOLUTION should be used with caution in patients with history of renal disease or renal impairment. Consult your doctor before receiving it.
LIVER
AMINOVEN 5% SOLUTION is not recommended for use in patients with liver diseases such as hepatic coma. AMINOVEN 5% SOLUTION should be taken with caution in patients with severe liver disease. Consult your doctor before receiving it.
ALLERGY
Do not receive AMINOVEN 5% SOLUTION if you are allergic to Amino acid or any of the other ingredients of this medicine.
LUNGS
AMINOVEN 5% SOLUTION is not recommended for use in patients with lung diseases such as pulmonary edema. AMINOVEN 5% SOLUTION should be used with caution in patients with lung disease. Consult your doctor before receiving it.
HEART DISEASE
AMINOVEN 5% SOLUTION should be used with caution in patients with cardiac insufficiency or severe congestive heart failure. Consult your doctor before receiving it.
OTHERS
AMINOVEN 5% SOLUTION is not recommended for use if you have:
- amino acid metabolism problems since birth, due to risk of severe metabolic or neurologic complications
- acidosis (acid build-up)
- metabolic disorders with impaired nitrogen utilization
- azotemia (build-up of nitrogenous products in blood)
Before receiving AMINOVEN 5% SOLUTION, inform your doctor if you have:
- conditions involving edema with sodium retention
- high blood potassium levels or potassium retention
- diabetes or are pre-diabetic
Use in pediatrics:
AMINOVEN 5% SOLUTION is not recommended for use in children as safety and efficacy of the medicine has not been studies in them. Consult your doctor before receiving it.
Use in geriatrics:
AMINOVEN 5% SOLUTION should be used with caution in elderly patients (aged above 65 years). Consult your doctor before receiving it.
INTERACTIONS
A. Drug - Drug interactions:
Before receiving AMINOVEN 5% SOLUTION, inform your doctor if you are taking any of the following medicine:
- tetracycline (used to manage bacterial infections)
Overdosage:
AMINOVEN 5% SOLUTION will be administered to you only by a doctor or a nurse in a hospital, and so you are unlikely to receive an overdose. However, consult your doctor or nurse if you experience any unusual symptoms.
SYNOPSIS
| Drug | : | Amino acid |
| Pharmacological Category | : | Naturally occurring physiological compounds |
| Therapeutic Indication | : | Protein depletion |
| Dosage Forms | : | Injection, Infusion |
MORE INFORMATION
- Keep AMINOVEN 5% SOLUTION out of reach of children
- Store AMINOVEN 5% SOLUTION between 20-25°C
FAQs ABOUT AMINOVEN 5% SOLUTION
Can AMINOVEN 5% SOLUTION be taken in pregnancy?
AMINOVEN 5% SOLUTION should be used in pregnant women only if considered clearly necessary. If you are pregnant, think you may be pregnant or are planning to get pregnant, consult your doctor before receiving this medicine. Inform your doctor immediately if you become pregnant during management with AMINOVEN 5% SOLUTION.
Does AMINOVEN 5% SOLUTION help lose weight?
AMINOVEN 5% SOLUTION may help you lose weight, depending on whether you are deficient or not. It is a simple and effective solution and offers great benefits in achieving weight loss if you are deficient in a key amino acid required for the metabolic process. It can give your body the nutrition it needs so that you feel your best and can burn more calories. Consult your doctor before receiving it.
Can AMINOVEN 5% SOLUTION be stopped by my own?
Continue receiving AMINOVEN 5% SOLUTION until your doctor tells you to stop, unless you experience any unwanted effects, worsening of your condition or any new symptoms. In such case, contact your doctor right away.
Can AMINOVEN 5% SOLUTION be used in diabetic patients?
Administration of AMINOVEN 5% SOLUTION in diabetic patients or patients with impaired glucose tolerance may further increase blood sugar levels. Frequent blood-sugar level measurements should be performed on diabetic patients receiving this medicine.
What precautions do I need to follow while taking AMINOVEN 5% SOLUTION?
Patients receiving AMINOVEN 5% SOLUTION must inform their doctor about their pre-existing conditions like kidney, liver, or heart problems, diabetes, or amino acid metabolism problems since birth. Patients should also inform if they are pregnant, breast-feeding, or having any allergies. Consult your doctor if you experience anything different.
Can AMINOVEN 5% SOLUTION cause nausea?
Nausea is a common side effect of AMINOVEN 5% SOLUTION. If you feel nauseous, take regular sips of a cold drink, or have ginger or peppermint tea. Stick to simple meals and avoid eating oily or spicy foods. If nausea does not improve, contact your doctor.
Can I take other medicines with AMINOVEN 5% SOLUTION?
Before receiving AMINOVEN 5% SOLUTION, inform your doctor if you are taking, have taken, or might take any other medicine, including prescription, non-prescription or any herbal medicine, as these might interact with each other and cause serious side effects.
REFERENCES
1. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo. Care of the Hospitalized Patient. Harrison’s Manual of Medicine. 18th edition. Page- 50.
2. Liebau, F., Sundström, M., van Loon, L.J. et al. Short-term amino acid infusion improves protein balance in critically ill patients. Critical Care. BMC. December 2015. [Accessed on 16th July 2022] https://ccforum.biomedcentral.com/articles/10.1186/s13054-015-0844-6
3. Shi Y, Song H, Liu J, Lin J, Fang L. Comprehensive Evaluation of Clinical Application of Balanced Compound Amino Acid Injection. NIH National Library of Medicine, National Centre for biotechnology information. PubMed Central. June 2022. [Accessed on 16th July 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203120/
4. Baxter Healthcare Corporation. Amino acid. [Revised in October 2020] [Accessed on 16th July 2022] https://www.baxterpi.com/pi-pdf/Travasol_PI.pdf
5. Hospira Healthcare Corporation. Amino acid. [Revised in April 2012] [Accessed on 16th July 2022] https://pdf.hres.ca/dpd_pm/00016324.PDF
6. La Renon Healthcare Pvt. Ltd. Amino acid. [Accessed on 16th July 2022] https://www.larenon.com/wp-content/uploads/2019/01/1.-Lamino-8.pdf
7 Innovative Pharmaceuticals. Amino acid. [Accessed on 16th July 2022] https://www.innovativepharma.in/product/aminozen-infusion/
USEFUL DIAGNOSTIC TESTS
- Total protein test
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