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Introduction About AMBRODIL PLUS RF SYRUP
AMBRODIL PLUS RF SYRUP contains Ambroxol, Chlorpheneramine maleate, Pseudoephedrine which belongs to the group of medicines called mucolytic agents, antihistamines, and nasal decongestants. It is used in adults and children above 6 years to manage the symptoms of the common cold, flu and allergy such as sneezing, running nose, nasal block, watery eyes, itching, cough, and sinus block.
Additionally, GBNKEYWORD] loosens and thins up the mucus, so it helps to cough out mucus easily. AMBRODIL PLUS RF SYRUP can also be used to relieve redness, itching, and swelling of the skin associated with insect bites, food allergies, and hay fever (seasonal allergy).
AMBRODIL PLUS RF SYRUP is also not recommended in patients suffering from high blood pressure, heart diseases, diabetes, severe kidney diseases, an overactive thyroid gland, glaucoma (an eye disease), a tumour that affects blood pressure and heart rate (phaeochromocytoma), asthma attacks, etc.
Before taking AMBRODIL PLUS RF SYRUP, inform your doctor if you have kidney diseases, serious liver diseases, blockages in blood vessels, thyroid diseases, peptic ulcers, an enlarged prostate gland, fits, intestinal obstruction, etc. AMBRODIL PLUS RF SYRUP is not recommended for use in patients who are pregnant (especially in the first trimester), breastfeeding, or in children below the age of 6 years.
The most common side effects of taking AMBRODIL PLUS RF SYRUP are headache, nausea, dry mouth, dizziness, nervousness, difficulty sleeping, altered taste, etc. Consult your doctor if any of the symptoms are worsening.
Uses Of AMBRODIL PLUS RF SYRUP
It is used in adults and children above 6 years to manage symptoms of:
- common cold, flu and allergies (symptoms include includes red, itchy, watery eyes, sneezing, itchy nose, or throat, running nose, blocked or stiffed nose, throat pain, dry cough, sinus block etc.)
- food allergy, hay fever (seasonal allergy) and insect bite (symptoms such as hives and rashes, itching and swelling)
- to eliminate (cough out)phlegm in respiratory diseases like pneumonia
How AMBRODIL PLUS RF SYRUP Works
AMBRODIL PLUS RF SYRUP contains ambroxol, chlorpheneramine maleate, and pseudoephedrine. Ambroxol is a mucolytic agent that manages the excess secretion of mucus, lowers phlegm viscosity, and improves the mucociliary transport of bronchial secretions. Thus, it helps in the removal of phlegm associated with respiratory diseases by coughing it out.
Chlorpheniramine is an antihistamine that blocks the effect of histamines (chemicals produced by the body in response to allergens) and manages the release of allergy-causing chemicals that are responsible for the symptoms of itching in the eyes, watery eyes, sneezing, running or blocked nose, and skin rashes. Pseudoephedrine works by reducing the swelling of the blood vessels in the nose. This helps mucus and air movement in the sinuses (the nasal air cavity) and helps people breathe easier.
How to use AMBRODIL PLUS RF SYRUP
Take AMBRODIL PLUS RF SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of AMBRODIL PLUS RF SYRUP
Common
- headache
- dry mouth
- nausea
- dizziness
- nervousness
- difficulty getting sleep
- altered taste
- numbness in throat and mouth
Uncommon
- vomiting
- loose motions
- digestive problems
- dryness in the mouth
- stomach pain
Rare
- rashes
- hives (urticaria)
- hypersensitivity reactions
- constipation
- weakness and vomiting
- dryness in mouth (xerostomia)
- running nose
Stop taking AMBRODIL PLUS RF SYRUP and contact your doctor immediately if you experience any of the following effects:
- pain in the chest, neck, back, jaw, shoulders, or arms (symptoms of reduced blood supply to heart- angina) or heart attack
- weakness in the face, tiredness, difficulty walking and speaking (symptoms of stroke)
- skin rash that may be itchy, red, swollen, blistered or peeling skin (symptoms of serious skin reactions like toxic epidermal necrolysis, Steven’s johns’ disease etc)
- sudden onset of fever, severe headache, tiredness, vomiting, confusion, fits, vision disturbances
- dryness in the throat
- swelling in face, lip, tongue, mouth, and throat with difficulty in swallowing and breathing (symptoms of angioedema)
- seeing, hearing, and smelling of things that are not there (hallucinations) and irrational feelings and thoughts
- stomach pain and rectal bleeding (symptoms of inflammation of the colon)
- sudden loss or decrease in seeing (symptoms of optic nerve damage- ischaemic optic neuropathy)
- lesions in the inner lining of the mouth, throat, nose eyes and genitals
- increased heart rate, fall in blood pressure, difficulty standing up, loss of consciousness etc (symptoms of anaphylactic shock)
- Difficulty concentrating, irritability, depression
- Hyperactivity in children
- Restlessness and disturbed sleep
- Yellowing of skin and eyes (symptoms of liver problems)
- Difficulty to pass urine
How To Manage Side Effects
Diarrhea
Keep yourself hydrated by drinking plenty of fluids and electrolytes such as ORS. Consult a doctor before taking any medication.
Dry Mouth
Drink plenty of fluids and stay hydrated. Chew sugar-free gums or chocolates that stimulate saliva production. Consult a doctor before starting any medication.
Headache
Drink plenty of fluids and stay hydrated. Try to be tension free and relaxed. Take adequate sleep and rest. Avoid consumption of alcohol. Apply pain balm if required. Consult your doctor if it is getting worsened.
Nausea And Vomiting
Avoid eating fried and greasy food. Take simple, light, small meals at frequent intervals. Keep yourself hydrated by drinking lots of fluids.
Warning & Precautions
Pregnancy
ContraindicatedAMBRODIL PLUS RF SYRUP is not recommended if you are pregnant, especially in the first trimester. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Breastfeeding
ContraindicatedAMBRODIL PLUS RF SYRUP is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Driving and Using Machines
Use with CautionDo not drive or operate any machines while taking AMBRODIL PLUS RF SYRUP as it may make you sleepy during the daytime, dizzy, drowsy, blurred vision, unable to concentrate or make decisions, clumsy, and have altered visual-motor coordination. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Alcohol
ContraindicatedDo not consume alcohol while taking AMBRODIL PLUS RF SYRUP as it may make you sleepier. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Kidney
Consult your doctorAMBRODIL PLUS RF SYRUP is not recommended in patients with severe kidney diseases. AMBRODIL PLUS RF SYRUP should be used with caution in patients with kidney diseases like difficulty passing urine or impaired renal function. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Liver
Use with CautionAMBRODIL PLUS RF SYRUP should be taken with caution in patients diagnosed with serious liver diseases (moderate to severe liver failure). Consult your doctor before taking it.
Allergy
ContraindicatedDo not take AMBRODIL PLUS RF SYRUP if you are allergic to ambroxol, chlorpheneramine maleate, or pseudoephedrine. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Lungs
Consult your doctorAMBRODIL PLUS RF SYRUP is not recommended for use in patients suffering from asthmatic attacks. AMBRODIL PLUS RF SYRUP should be taken with caution in children suffering from asthma, bronchitis, bronchiectasis, bronchial motor activity disorder, or large production of secretion or mucus. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Heart Disease
ContraindicatedAMBRODIL PLUS RF SYRUP is not recommended in patients with heart diseases, high blood pressure, or pheochromocytoma (a tumour that affects heart rate and blood pressure). Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Use In Pediatrics
ContraindicatedAMBRODIL PLUS RF SYRUP is not recommended to take in children below 6 years of age. Consult a doctor before taking AMBRODIL PLUS RF SYRUP.
Use In Geriatrics
ContraindicatedAMBRODIL PLUS RF SYRUP is not recommended to use in weak elderly patients due to the experience of serious side effects such as confusion. Consult a doctor before taking AMBRODIL PLUS RF SYRUP.
Others
AMBRODIL PLUS RF SYRUP is not recommended to take if you have:
- diabetes
- overactive thyroid gland
- glaucoma (increased pressure inside eyes)
- taking other cough syrups
Before taking AMBRODIL PLUS RF SYRUP, inform your doctor if you have:
- allergy to any food or medicine
- fits
- enlarged prostate
- overactive thyroid gland
- ulcer in the stomach or intestine
- block in blood vessels
- obstruction to the intestine
- blood disorders like porphyria
- sugar intolerance
- weakness due to old age
- glaucoma
Interactions
A. Drug-Drug interactions:
Before taking AMBRODIL PLUS RF SYRUP inform your doctor if you are taking the following medicines:
- medicines used to manage depression (ex. tricyclic antidepressants such as nortriptyline, desipramine etc and monoamine oxidase inhibitors such as tranylcypromine, isocarboxacid etc)
- medicines used to manage cramps (ex. anticholinergic drugs like atropine, scopolamine etc)
- medicines used to manage increased blood pressure (ex. methyldopa, atenolol, propranolol, guanethidine, debrisoquine, bretylium and betanidine etc)
- medicine used to manage mood disorders (moclobemide)
- medicine used to manage heart problems (ex. atropine, digoxin, amiodarone)
- medicines used to manage migraine (ex. ergotamine and methysergide)
- medicine used to control pregnancy (ex. ethinylestradiol, oxytocin)
- medicines used to manage chest congestion and asthma (ex. budesonide, prednisolone)
- medicines used to manage cough and cold (ex. dextromethorphan, oxymetazoline)
- medicines used to get sleep and relaxation (ex. clonazepam, triazolam, zolpidem, barbiturates, diazepam etc)
- medicines used to relieve pain (ex. tramadol, methadone etc)
- medicines used to manage allergy (ex. antihistamines like diphenhydramine, cetirizine etc)
- medicine used to manage fits (phenytoin)
- medicines used to manage mood disorders (ex. diazepam, clonazepam etc)
- medicines used to manage bacterial infections (ex. amoxycillin, erythromycin, doxycycline, cefuroxime)
- medicines containing alcohol as an ingredient (ex. cough syrups like Benadryl)
- any herbal or homoeopathic medicines
Overdosage:
If you or anyone else accidentally took too more of this medicine, consult your doctor immediately. Symptoms include nausea, vomiting , and stomach pain.
Synopsis
| Drug | : | Ambroxol, Chlorpheneramine maleate, Pseudoephedrine |
| Pharmacological Category | : | Mucolytics, Antihistamines, Nasal decongestants |
| Therapeutic Indication | : | Used to manage symptoms cold, allergies and flu, insect bite, food allergy , hay fever(seasonal allergy) and other respiratory diseases |
| Dosage Forms | : | Syrup |
More Information
- Keep AMBRODIL PLUS RF SYRUP out of reach of children
- Store AMBRODIL PLUS RF SYRUP at room temperature
FAQs About AMBRODIL PLUS RF SYRUP
Q: What is AMBRODIL PLUS RF SYRUP used for?
A: AMBRODIL PLUS RF SYRUP is used in adults and children above 6 years old to manage the symptoms of a common cold, flu, and allergy, such as sneezing, running nose, nasal block, watery eyes, itching, coughing, and sinus block. Additionally, GBNKEYWORD] loosens and thins up the mucus, so it helps to cough out mucus easily. AMBRODIL PLUS RF SYRUP can also be used to relieve redness, itching, and swelling of the skin associated with insect bites, food allergies, and hay fever (seasonal allergy).
Q: What are the common side effects of taking AMBRODIL PLUS RF SYRUP?
A: The most common side effects of taking AMBRODIL PLUS RF SYRUP are headache, nausea, dry mouth, dizziness, nervousness, difficulty sleeping, altered taste, etc. Consult your doctor if any of the symptoms are worsening while taking AMBRODIL PLUS RF SYRUP.
Q: Can I use AMBRODIL PLUS RF SYRUP for managing rashes and itching due to insect bites?
A: AMBRODIL PLUS RF SYRUP contains chlorpheneramine as an ingredient. Chlorpheneramine is an antihistamine that blocks the effect of histamines (chemicals produced by the body in response to allergens) and manages the release of allergy-causing chemicals, which are responsible for the symptoms of itching and rashes. So, it can be used for the management of insect bites. Consult a doctor before taking AMBRODIL PLUS RF SYRUP.
Q: Can I drive a car or bike while taking AMBRODIL PLUS RF SYRUP?
A: Do not drive or operate any machines while taking AMBRODIL PLUS RF SYRUP as it may make you sleepy during the daytime, dizzy, drowsy, blurred vision, unable to concentrate or make decisions, clumsy, and have altered visual-motor coordination. Consult your doctor before taking AMBRODIL PLUS RF SYRUP.
Q: Can I use AMBRODIL PLUS RF SYRUP during pregnancy?
A: AMBRODIL PLUS RF SYRUP is not recommended for use in pregnancy, especially in the first trimester. Consult a doctor before taking AMBRODIL PLUS RF SYRUP.
References
1. KD Tripathi. Autocoids and related drugs. Essentials of Medical Pharmacology. 8th edition. 2019. Page – 238, 239.
2. Tashiro, Manabu, Yumiko Sakurada, Hideki Mochizuki, Etsuo Horikawa, Masahiro Maruyama, Nobuyuki Okamura, Shoichi Watanuki, Hiroyuki Arai, Masatoshi Itoh, and Kazuhiko Yanai. Effects of a sedative antihistamine, d-chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving. Tashiro, Manabu, Yumiko Sakurada, Hideki Mochizuki, Etsuo Horikawa, Masahiro Maruyama, Nobuyuki Okamura, Shoichi Watanuki, Hiroyuki Arai, Masatoshi Itoh, and Kazuhiko Yanai. Effects of a sedative antihistamine, d-chlorpheniramine, on regional cerebral perfusion and performance during simulated car driving. Human Psychopharmacology: Clinical and Experimental 23, no. 2 (2008). [Published on 8th January 2008] [Accessed on 26th August 2022] https://onlinelibrary.wiley.com/doi/abs/10.1002/hup.909
3. Delpharm Orleans. Electronic Medicines Compendium (EMC). [Revised in May 2022] [Accessed on 26th August 2022] https://www.medicines.org.uk/emc/files/pil.6198.pdf
4. The Boots Company. Electronic Medicines Compendium (EMC). [Accessed on 26th August 2022] https://www.medicines.org.uk/emc/files/pil.3866.pdf
5. Rotapharm. Ambroxol. [Accessed on 26th August 2022] http://www.rotapharm.co.uk/wp-content/uploads/Bronolac.pdf
6. CINFA, S.A. Ambroxol. [Revised in May 2016] [Accessed on 26th August 2022] https://www.cinfainternational.com/wp-content/uploads/PIL_ambroxol_HK.pdf
7. Sandoz d.d. Ambroxol. [Revised in June 2016] [Accessed on 26th August 2022] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_10403_ENG.pdf
8. Johnson & Johnson (Ireland) Ltd. Pseudoephedrine. [Revised in February 2021] [Accessed on 26th August 2022] https://www.medicines.ie/medicines/non-drowsy-sudafed-decongestant-30mg-5ml-syrup-33105/patient-info#tabs
Useful Diagnostic Tests
- Blood examination
- Sputum tests
- Chest x-ray
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