AMARYL 2MG TABLET 30'S(L)
Netmeds First Membership
Quick Links
Introduction About AMARYL 2MG TABLET 30'S(L)
AMARYL 2MG TABLET 30'S(L) contains Glimepiride which belongs to the group of medicines called Anti-diabetic agents. It is used for the management of Type II diabetes mellitus when diet and exercise alone does not result in adequate blood sugar control. Type II diabetes mellitus is a chronic disease characterized by abnormally high levels of glucose in the blood. It is caused due to inadequate production of a hormone called insulin (produced by pancreas to metabolize glucose) in the body or due to inadequate sensitivity of body cells to the actions of insulin. Along with the therapy, your doctor might ask you to make certain lifestyle changes such as following a healthy diet, regular physical exercise and quitting alcohol consumption.
Before taking AMARYL 2MG TABLET 30'S(L), inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have any hormonal problems, genetic disorders (such as G6PD deficiency) or if you are malnourished, starved, on an irregular diet. AMARYL 2MG TABLET 30'S(L) is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking AMARYL 2MG TABLET 30'S(L) if you are pregnant or planning to become pregnant or breastfeeding.
The most common side effect of taking AMARYL 2MG TABLET 30'S(L) is hypoglycemia (low blood sugar levels) which can be identified through symptoms such as increased hunger, sweating, shakiness, weakness or an irregular heartbeat. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of AMARYL 2MG TABLET 30'S(L) accordingly. You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypoglycemia. However, consult your doctor if there is no improvement in your condition.
Uses Of AMARYL 2MG TABLET 30'S(L)
- Used to manage Type II diabetes mellitus
How AMARYL 2MG TABLET 30'S(L) Works
AMARYL 2MG TABLET 30'S(L) stimulates the pancreas to secrete more insulin (a hormone involved in glucose metabolism). It also makes our body more sensitive to insulin which helps in digesting the circulating sugars (glucose) in the blood, thereby reducing blood sugar levels.
How to use AMARYL 2MG TABLET 30'S(L)
Take AMARYL 2MG TABLET 30'S(L) preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking AMARYL 2MG TABLET 30'S(L) unless your doctor advice you to stop.
Side Effects Of AMARYL 2MG TABLET 30'S(L)
Common
- hypoglycemia (low blood sugar levels)
Rare
- decrease in RBC, WBC and platelet counts
- taste changes
- weight gain
- hair loss
Stop taking AMARYL 2MG TABLET 30'S(L) and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reaction (including inflammation of blood vessels, skin rash, swelling of the face, eyelids, lips, tongue or throat which causes difficulty in breathing or swallowing, drop in blood pressure)
- signs of liver problems (such as fever, yellowing of skin and whites of the eyes, weakness, fatigue, weight loss and loss of appetite)
- increased skin sensitivity to sun
- signs of severe decrease in blood sugar level (such as confusion, headache, excessive sweating, clammy skin, trembling, weakness, double vision, excessive hunger, nausea, vomiting, problems in sleeping, feeling agitated, unable to concentrate, drowsiness, slowed reactions, depression, trouble seeing or speaking, paralysis, numbness, dizziness, hallucinations, difficulty in breathing, slowed or faster heartbeat with chest pain)
How To Manage Side Effects
Hypoglycemia
Have foods rich in sugars such as fruit juices, glucose drinks, candies, honey or biscuits. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or a drink and check the blood sugar again. Consult your doctor if there is no improvement in your condition.
Warning & Precautions
Pregnancy
ContraindicatedAMARYL 2MG TABLET 30'S(L) is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
ContraindicatedAMARYL 2MG TABLET 30'S(L) is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionDo not drive or operate any heavy tools or machines if your ability is affected by AMARYL 2MG TABLET 30'S(L).
Alcohol
Consult your doctorAvoid consumption of alcohol while taking AMARYL 2MG TABLET 30'S(L) as it may increase the risk of unwanted side effects.
Kidney
Consult your doctorAMARYL 2MG TABLET 30'S(L) is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
Consult your doctorAMARYL 2MG TABLET 30'S(L) is not recommended for use in patients with severe liver problems. It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take AMARYL 2MG TABLET 30'S(L) if you are allergic to Glimepiride or to any other sulfonylureas (Ex. Glyburide, gliclazide) or sulphonamides (Ex. sulfasalazine).
Use In Pediatrics
ContraindicatedAMARYL 2MG TABLET 30'S(L) is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use In Geriatrics
Use with CautionAMARYL 2MG TABLET 30'S(L) should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
Others
AMARYL 2MG TABLET 30'S(L) is not recommended for use if you:
- have type I diabetes mellitus (insulin dependent diabetes)
- have diabetic ketoacidosis (a diabetic complication causing episodes of fatigue, nausea, frequent urination and muscular stiffness)
Before taking AMARYL 2MG TABLET 30'S(L), inform your doctor if you:
- are recovering from any injury, operation, infections or from any form of stress
- have G6PD deficiency
- have sugar intolerance
- are malnourished, starved, on an irregular diet, or feeling weak
- had made any sudden changes to your diet
- are on fasting
- perform extreme physical exercises without proper carbohydrate intake
- have hormonal problems (Ex. disorders of pituitary gland, adrenal cortex or thyroid gland)
- are alcoholic
Interactions
A. Drug-Drug interactions:
Before taking AMARYL 2MG TABLET 30'S(L), inform your doctor if you are taking any of the following medicines:
- other medicines used to manage diabetes mellitus (such as insulin or metformin)
- medicines used for pain and inflammation (Ex. aspirin, ibuprofen, phenylbutazone, azopropazone, oxyphenbutazone)
- medicines used to manage urinary infections (amikacin, nitrofurantoin, sulfamethoxazole)
- medicines used for bacterial infections (such as tetracyclines, chloramphenicol, ciprofloxacin, clarithromycin)
- medicines used for fungal infection (Ex. fluconazole, miconazole)
- medicines used for blood clotting (Ex. warfarin)
- medicines used for muscle build-up (Ex. nandrolone, oxymethalone)
- medicines used for male sex hormone replacement therapy (Ex. testosterone)
- medicines used for depression (such as moclobemide, isocarboxazid, phenelzine, tranylcypromine, fluoxetine)
- medicines used for high blood cholesterol levels (Ex. fenofibrate, nicotinic acid, colesevelam)
- medicines used to manage high blood pressure (Ex. enalapril, lisinopril, ramipril, atenolol, propranolol, telmisartan, olmesartan, clonidine, guanethidine and reserpine)
- disopyramide (used to manage abnormal heartbeat)
- medicines used for gout (Ex. allopurinol, probenecid, sulfinpyrazone)
- medicines used for cancer (Ex. cyclophosphamide, ifosfamide, trofosfamide)
- fenfluramine (used for obesity)
- pentoxifylline (helps to improve blood flow in the body)
- medicines used to manage allergic rhinitis (Ex. tritoqualine)
- alpha blockers (medicines used to manage high blood pressure or prostate problems) Ex. prazosin, doxazosin
- hormonal replacement therapy (used for menstrual disorders in women) Ex. estradiol
- thiazide diuretics (used to manage edema and high blood pressure) Ex. hydrochlorothiazide
- levothyroxine (used for thyroid problems)
- used for mental illness (such as chlorpromazine, prochlorperazine, lithium)
- corticosteroids (for pain and inflammation) Ex. prednisolone, betamethasone
- used for asthma (Ex. salbutamol, terbutaline)
- adrenaline (used in emergency condition)
- medicines used to manage constipation (Ex. lactulose, liquid paraffin)
- medicines used to manage epilepsy (Ex. phenytoin)
- barbiturates (used to induce sleep) Ex. phenobarbital
- medicines used to reduce increased pressure in the eye (Ex. azetazolamide)
- glucagon, diazoxide (medicines used to manage signs of low blood sugar levels)
- cimetidine (a medicine used for stomach ulcers)
Overdosage:
If you or anyone else accidentally took more AMARYL 2MG TABLET 30'S(L), you may experience the signs of hypoglycemia (such as increased hunger, sweating, headache, feeling clammy, restless or aggressive, shakiness, fast heartbeat and confusion). To manage this, consume any sugary food immediately. If the symptom did not improve or worsens contact your doctor immediately.
Synopsis
| Drug | : | Glimepiride |
| Pharmacological Category | : | Sulfonylureas |
| Therapeutic Indication | : | Type 2 diabetes mellitus |
| Dosage Forms | : | Tablet |
More Information
- Keep AMARYL 2MG TABLET 30'S(L) out of reach of children
- Store AMARYL 2MG TABLET 30'S(L) at room temperature
FAQs About AMARYL 2MG TABLET 30'S(L)
Q: What is AMARYL 2MG TABLET 30'S(L) used for?
A: AMARYL 2MG TABLET 30'S(L) is an antidiabetic medicine used to manage Type II diabetes mellitus when diet, exercise and lifestyle changes alone does not result in adequate response.
Q: How and when to take AMARYL 2MG TABLET 30'S(L)?
A: Take AMARYL 2MG TABLET 30'S(L) preferably after meals or as advised by your physician. Swallow the medicine with a glass of water. Do not cursh or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: How long should I take AMARYL 2MG TABLET 30'S(L)?
A: You need to take AMARYL 2MG TABLET 30'S(L) as long as your doctor or physician prescribes you the medicine. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition.
Q: What is the best time to take AMARYL 2MG TABLET 30'S(L)?
A: AMARYL 2MG TABLET 30'S(L) must be taken with meals to avoid gastrointestinal side effects. Consult your doctor for advice.
Q: What to do if I forgot to take a dose of AMARYL 2MG TABLET 30'S(L)?
A: If you forgot to take a dose of AMARYL 2MG TABLET 30'S(L), take it as soon as you remember. However, if it is time for the next dose of AMARYL 2MG TABLET 30'S(L), skip the missed dose and take the next one regularly. Do not take a double dose of AMARYL 2MG TABLET 30'S(L) to compensate the missed ones.
Q: What are the most common side effects of taking AMARYL 2MG TABLET 30'S(L)?
A: The most common side effects of taking AMARYL 2MG TABLET 30'S(L) is hypoglycemia. To avoid this, your doctor will periodically monitor your blood sugar levels and adjust the dose of AMARYL 2MG TABLET 30'S(L) accordingly. You can also carry a sugary snack (such as biscuits, glucose drinks or sweet candies) along with you as a precaution and have them immediately if you experience any signs of hypoglycemia. However, consult your doctor if there is no improvement in your condition.
Q: Can I stop taking AMARYL 2MG TABLET 30'S(L) without consulting your doctor?
A: No. You should not stop taking AMARYL 2MG TABLET 30'S(L) without consulting your doctor because it may lead to reversal of symptoms. If you feel better after using AMARYL 2MG TABLET 30'S(L), consult your doctor for advice.
Q: Will taking a higher dose of AMARYL 2MG TABLET 30'S(L) be more effective?
A: No, taking a higher dose of AMARYL 2MG TABLET 30'S(L) will not be effective rather it can lead to unwanted side effects. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: What precautions do I need to follow while taking AMARYL 2MG TABLET 30'S(L)?
A: Before taking AMARYL 2MG TABLET 30'S(L), inform your doctor if you have any liver or kidney problems. You must also inform your doctor if you have hormonal problems, genetic problems (surgery in the gut) or if you are malnourished. AMARYL 2MG TABLET 30'S(L) is not suitable for use in patients with type I diabetes mellitus. Consult your doctor before taking the medicine.
Q: Can I take medication for high blood pressure along with AMARYL 2MG TABLET 30'S(L)?
A: It is not advisable to take medicines to control blood pressure while taking AMARYL 2MG TABLET 30'S(L) without consulting your doctor. Therefore, consult your doctor before taking any antihypertensive such as beta blockers (Ex. atenolol, propranolol) along with AMARYL 2MG TABLET 30'S(L) as they have known interactions with AMARYL 2MG TABLET 30'S(L).
Q: What should I do if I experience low blood sugar after taking AMARYL 2MG TABLET 30'S(L)?
A: Low blood sugar is a common side effect of taking AMARYL 2MG TABLET 30'S(L). Try to have sugar rich food items such as fruit juice, glucose tablets or gel, soft drinks, honey or sugary candy. Check your blood sugar after 10 minutes. If not gained optimum level, take another sugary snack, or drink, and check the blood sugar levels once again. In case of persistent low blood sugar levels, consult your doctor immediately.
Q: Can AMARYL 2MG TABLET 30'S(L) be taken with insulin?
A: Co-administration of AMARYL 2MG TABLET 30'S(L) with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.
Q: Can AMARYL 2MG TABLET 30'S(L) be used in pregnant women?
A: AMARYL 2MG TABLET 30'S(L) is not recommended for use in pregnant women. Therefore, consult your doctor for advice before taking it.
Q: How to take AMARYL 2MG TABLET 30'S(L)?
A: You must take AMARYL 2MG TABLET 30'S(L) as advised by your physician. Try to take this medicine preferably after meals and swallow it with a glass of water. Do not crush or chew the medicine.
Q: How much AMARYL 2MG TABLET 30'S(L) should I take?
A: AMARYL 2MG TABLET 30'S(L) should be used only under medical supervision. Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body condition and severity of the disease condition.
References
1. KD. Tripathi. Insulin, Oral Hypoglycaemic Drugs and Glucagon. Essentials of medical pharmacology. Seventh edition. 2013. Page – 270.
2. Abdul Basit, Musarrat Riaz and Asher Fawwad. Glimepiride: evidence-based facts, trends, and observations. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. August 2012. [Accessed on 14th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448454/
3. Brown & Burk UK Limited. Electronic Medicines Compendium (EMC). [Revised in December 2020] [Accessed on 14th October 2022] https://www.medicines.org.uk/emc/files/pil.10742.pdf
4. Sanofi India Limited. Amaryl® / Semi-Amaryl® Glimepiride Tablets IP. [Revised in April 2021] [Accessed on 14th October 2022] https://www.sanofi.in/dam/jcr:08a3cd36-a9e7-49eb-887b-9914600a6335/Amaryl%20and%20Semi-Amaryl%20%2005mg%20PI%20-%20rev%20April%202021.pdf
Useful Diagnostic Tests
- HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
- Blood Glucose Fasting (FBS)
- Post Prandial Blood Sugar (PPBS)
- Insulin - Fasting
- Netmeds Diabetic Checkup
- Advance Diabetes Monitoring (Senior Female)
- Jaanch Diabetic Profile Basic
Author Details
