New Revised MRP, 100% GST benefit passed ALTONIL PLUS 5 Tablet 15's
Netmeds First Membership
Quick Links
Introduction About ALTONIL PLUS 5 TABLET
ALTONIL PLUS 5 TABLET is a combination of Clonazepam and Melatonin which belongs to the group of medicines called Anticonvulsants and Sedatives respectively. It is used to manage epilepsy (fits), panic disorder, and certain types of phobia (fears). It can also be used in the management of sleep disorders (such as jet lag or sleeplessness (insomnia)) that is caused due to disturbance in the body’s biological day- and night- rhythm.
It also helps the children with autism or Smith-Magenis syndrome (a genetic brain disease) to sleep faster and longer. Take ALTONIL PLUS 5 TABLET before meals or as directed by your physician.
Before taking ALTONIL PLUS 5 TABLET, inform your doctor if you have any problems in your liver, kidney or heart. You must also inform your doctor if you have diabetes, weak muscles, any autoimmune disease, trouble breathing, previous history of drug abuse, alcohol abuse or depression as a precaution.
Do not take ALTONIL PLUS 5 TABLET without consulting your doctor if you are pregnant or breastfeeding. The most common side effects of taking ALTONIL PLUS 5 TABLET are dizziness, drowsiness, tiredness, weak muscles, memory loss, headache, nausea, stomach upset, hair loss and low sex drive. Consult your doctor if any of these side effect troubles you.
You must also inform your doctor immediately if you experience worsening of depression along with suicidal thoughts as a precaution.
Uses Of ALTONIL PLUS 5 TABLET
- Manage and manages epilepsy (fits)
- Manage panic disorder and phobias (fear)
- Induces sleep and regulates sleep-wake up cycle
How ALTONIL PLUS 5 TABLET Works
ALTONIL PLUS 5 TABLET contains two medicines namely clonazepam and melatonin. Clonazepam is an anticonvulsant medication. It works by suppressing the abnormal electrical activity within the brain cells. It reduces seizure outbursts, anxiousness and induces calmness.
Melatonin helps in synchronizing the body’s sleep wakefulness cycle (day- and night- rhythm). This reduces the signs of sleep disorders and corrects sleep cycle among people travelling across different time zones. Collectively, this medicine calms your brain and helps you fall asleep.
How to use ALTONIL PLUS 5 TABLET
Take ALTONIL PLUS 5 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. It must be taken either 2 hours before or after a meal.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease conditions.
Side Effects Of ALTONIL PLUS 5 TABLET
Common
- dizziness, drowsiness, tiredness
- weak muscles, poor muscle control, loss of balance
- poor concentration, confusion, memory loss, restlessness
- headache
- slow or difficult speech
- urge to pass urine
- blood problems (causing tiredness, bruising, shortness of breath and nose bleeds)
- nausea, stomach upset
- blurred vision
- skin rash or itching
- hair loss
- low sex drive, difficulty in erection
Uncommon
- feeling irritated, nervous or restless
- abnormal dreams, anxiety
- high blood pressure
- upper stomach pain, indigestion
- mouth ulcers, dry mouth
- dry skin
- sugar in protein
- excess protein in the urine
- weight gain
Rare
- high lipid levels in blood
- increased sex drive
- watery eyes, hot flushes
- excess saliva, bad breath
- nail disorder
- joint pain, muscle spasms
- passing large amount of urine, thirst
Stop taking ALTONIL PLUS 5 TABLET and contact your doctor immediately if you experience any of the following side effects:
- suicidal thoughts and behaviour
- signs of allergic reactions (such as skin rash, itching, swellling of the face, lips, tongue and throat which causes difficulty in breathing or swallowing)
- changes in behavior (such as feeling agitated, restless, aggressive, irritable, violent or angry, false beliefs, nightmares and hallucinations or other inappropriate behavior)
- fits
- signs of heart problems (such as fast or irregular heart rate, chest pain, swollen ankles, fainting, dizziness upon standing)
- breathing difficulties, chest pain, fast heartbeat
- low RBC, WBC and platelet count in blood
- excessive sleepiness
- prolonged painful erections
How To Manage Side Effects
Dizziness Or Drowsiness
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Consult your doctor if your dizziness worsens.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take ALTONIL PLUS 5 TABLET with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedALTONIL PLUS 5 TABLET is generally not recommended for use in pregnant women, as it may harm the growing baby. Therefore, inform your doctor before taking it. Women of childbearing potential must use a suitable contraceptive method to avoid pregnancy while taking this medicine.
Breastfeeding
ContraindicatedALTONIL PLUS 5 TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk to the nursing infant. Therefore, consult your doctor before taking it.
Driving and Using Machines
Use with CautionALTONIL PLUS 5 TABLET may cause sleepiness or dizziness. Therefore, do not drive or handle any heavy tools or machines if your ability is affected by ALTONIL PLUS 5 TABLET.
Alcohol
Consult your doctorAvoid consumption of alcohol while taking ALTONIL PLUS 5 TABLET as it might make this medicine less effective.
Kidney
Use with CautionALTONIL PLUS 5 TABLET should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
Consult your doctorALTONIL PLUS 5 TABLET is not recommended for use in patients with severe liver problems (such as liver cirrhosis). It should be used with caution in patients with other liver problems. Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take ALTONIL PLUS 5 TABLET if you are allergic to Clonazepam, Melatonin or to any other benzodiazepines (such as lorazepam, nitrazepam, etc.).
Lungs
Consult your doctorALTONIL PLUS 5 TABLET is not recommended for use in patients with severe lung problems (such as pulmonary insufficiency or respiratory insufficiency). It should be used with caution in patients with COPD. Therefore, consult your doctor before taking it.
Use In Pediatrics
ContraindicatedALTONIL PLUS 5 TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Use In Geriatrics
Use with CautionALTONIL PLUS 5 TABLET should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it.
Others
ALTONIL PLUS 5 TABLET is not recommended for use if you:
- have myasthenia gravis (severe muscle weakness)
- have sleep apnea (breathing stops and starts during sleep)
- have an history of alcoholism or drug abuse
Before taking ALTONIL PLUS 5 TABLET, inform your doctor if you:
- have previously experienced depression with thoughts of committing suicide
- are an alcoholic
- have poor muscle control caused due to problems in nervous system
- have porphyria (a rare inherited blood disorder)
- are scheduled for any operation in the upcoming days
- have an auto-immune disease
- have diabetes
- have an habit of smoking
Interactions
A. Drug-Drug interactions:
Before taking ALTONIL PLUS 5 TABLET, inform your doctor if you are taking any of the following medicine such as:
- medicines used to manage epilepsy (such as carbamazepine, phenytoin, phenobarbital, sodium valproate, primidone)
- medicines used for pain relief (such as aspirin, celecoxib, tramadol, ibuprofen, diclofenac)
- medicines used to manage high blood pressure (such as ramipril, candesartan, amlodipine, doxazosin)
- medicines used to reduce anxiety and to induce sleep (such as alprazolam, midazolam, lorazepam, nitrazepam, temazepam, zaleplon, zolpidem, zopiclone)
- muscle relaxants (used for muscle relaxation prior to surgeries) such as tubocurarine
- cimetidine (a medicine used for managing stomach ulcers)
- rifampicin (a medicine used to manage tuberculosis)
- opioid analgesic medications (such as buprenorphine, morphine, codeine or propoxyphene, pethidine, fentanyl etc.)
- cough medicines
- fluvoxamine (an antidepressant)
- psoralens (used for the management of skin disorders)
- estrogens (used in contraceptives or hormone replacement preparations) such as estradiol, ethinylestradiol
- quinolones (used in the management of bacterial infections) such as ciprofloxacin
- warfarin (a medicine used to manage blood clots)
B. Drug-Food interactions:
ALTONIL PLUS 5 TABLET should not be taken with food.
Overdosage:
If you or anyone else accidentally took more ALTONIL PLUS 5 TABLET, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include drowsiness, dizziness, headache, nausea low blood pressure and breathing difficulties.
Synopsis
| Drug | : | Clonazepam, Melatonin |
| Pharmacological Category | : | Benzodiazepines, Biogenic amine |
| Therapeutic Indication | : | Epilepsy, Panic attacks, Phobias, Sleep disorders |
| Dosage Forms | : | Tablet |
More Information
- Keep ALTONIL PLUS 5 TABLET out of reach of children
- Store ALTONIL PLUS 5 TABLET at room temperature
FAQs About ALTONIL PLUS 5 TABLET
Q: What is the use of ALTONIL PLUS 5 TABLET?
A: ALTONIL PLUS 5 TABLET is used to manage epilepsy (fits), panic disorder, and certain types of phobia (fears). It can also be used in the management of sleep disorders (such as jet lag or sleeplessness (insomnia)) that is caused due to disturbance in the body’s biological day- and night- rhythm and helps helps the children with autism or Smith-Magenis syndrome (a genetic brain disease) to sleep faster and longer.
Q: How ALTONIL PLUS 5 TABLET works in my body?
A: ALTONIL PLUS 5 TABLET suppresses the abnormal electrical activity within the brain. It reduces seizure outbursts and induces calmness. It also helps in synchronizing the body’s sleep wakefulness cycle (day- and night- rhythm) which reduces the signs of sleep disorders and corrects sleep cycle among people travelling across different time zones.
Q: Can ALTONIL PLUS 5 TABLET be used in children?
A: ALTONIL PLUS 5 TABLET is not recommended for use in children and adolescents (aged below 18 years). Therefore, consult your doctor before taking it.
Q: Can ALTONIL PLUS 5 TABLET be used during pregnancy?
A: ALTONIL PLUS 5 TABLET is generally not recommended for use in pregnant women, as it may harm the growing baby. Therefore, inform your doctor before taking ALTONIL PLUS 5 TABLET if you are pregnant, think you might be pregnant or planning to have a baby.
Q: Will the use of ALTONIL PLUS 5 TABLET cause sleepiness?
A: Yes, ALTONIL PLUS 5 TABLET can make your feel sleepy, drowsy, or tired. Therefore, do not drive or handle heavy machines or tool if you feel drowsy or sleepy. Avoid consumption of alcohol as it can aggravate your drowsiness.
Q: Can I consume alcohol while taking ALTONIL PLUS 5 TABLET?
A: Avoid consumption of alcohol while taking this medicine as it may make this medicine less effective.
Q: What to do if I forget to take a dose of ALTONIL PLUS 5 TABLET?
A: If you forget to take a dose of ALTONIL PLUS 5 TABLET, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of ALTONIL PLUS 5 TABLET to compensate a missed dose, as it could lead to toxicity.
Q: Will taking a higher dose of ALTONIL PLUS 5 TABLET than the prescribed one be beneficial?
A: No, taking a higher dose of ALTONIL PLUS 5 TABLET will not be effective rather it can lead to toxicity. Always take the dose prescribed by your doctor. If the prescribed dose is not effective for you, consult your doctor for advice. Your doctor might increase the dose or suggest an alternative therapy.
Q: Can ALTONIL PLUS 5 TABLET be taken daily?
A: Yes. ALTONIL PLUS 5 TABLET can be taken daily as per your doctor’s instruction. However, if you are doubtful, consult your doctor.
Q: What are the common side effects of taking ALTONIL PLUS 5 TABLET?
A: The most common side effects of taking ALTONIL PLUS 5 TABLET are dizziness, drowsiness, tiredness, weak muscles, memory loss, headache, nausea, stomach upset, hair loss and low sex drive.
Q: Will ALTONIL PLUS 5 TABLET reduce my sex drive?
A: Yes. ALTONIL PLUS 5 TABLET may affect your sexual life. It may decrease sex drive or cause problems in orgasm, ejaculation or erection. Therefore, consult your doctor if you experience any such symptoms.
References
1. KD. Tripathi. Drugs Acting on Central Nervous System. Sedatives and Hypnotics. Antiepileptic Drugs. Essentials of Medical Pharmacology. 7th Edition. Page – 409 & 418.
2. Hajira Basit; Chadi I. Kahwaji. Clonazepam. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2022. [Accessed on 27th February 2023] https://www.ncbi.nlm.nih.gov/books/NBK556010/
3. W. Shin, J.I. Byun. Efficacy of prolonged-release melatonin versus clonazepam for REM sleep without atonia in patients with newly diagnosed idiopathic REM sleep behavior disorder. Journal of the Neurological Sciences 405S (2019) 105467. [Accessed on 27th February 2023] https://www.jns-journal.com/article/S0022-510X(19)32281-6/pdf
4. Neuraxpharm UK Limited. Clonazepam Neuraxpharm 0.5 mg, 1 mg and 2 mg. Electronic Medicines Compendium. [Revised in October 2021]. [Accessed on 27th February 2023] https://www.medicines.org.uk/emc/files/pil.13633.pdf
5. Colonis Pharma Ltd. Melatonin 2 mg, 3 mg, 5 mg Hard Capsules. Electronic Medicines Compendium. [Revised in August 2021]. [Accessed on 27th February 2023] https://www.medicines.org.uk/emc/files/pil.11967.pdf
6. Iberfar – Indústria. slenyto 1 and 5mg prolonged-release tablets. Melatonin. Electronic Medicines Compendium. [Revised in October 2021]. [Accessed on 27th February 2023] https://www.medicines.org.uk/emc/files/pil.10024.pdf
Author Details
