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ALPHACYST M Tablet 10's

Diabetes
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    Introduction About ALPHACYST M TABLET

    ALPHACYST M TABLET is a combination of Alpha Lipoic Acid and Metformin, which belongs to the group of medicines called Antidiabetic agents. It is used in the management of diabetes mellitus and polycystic ovarian disease.

    During management with ALPHACYST M TABLET, your doctor will conduct a blood test to check for blood sugar levels and kidney function.

    ALPHACYST M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Inform your doctor if you are pregnant or planning to become pregnant before taking this medicine.

    ALPHACYST M TABLET is not recommended for use if you have severely reduced kidney function, liver disease, acute heart failure, a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties. Consult your doctor before taking it.

    The most common side effects of taking ALPHACYST M TABLET are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, changes in taste, and skin rash. Consult your doctor if any of the side effects worsen.

    Uses Of ALPHACYST M TABLET

    • To manage type II diabetes mellitus and polycystic ovarian disease

    How ALPHACYST M TABLET Works

    ALPHACYST M TABLET effectively controls blood glucose levels and polycystic ovarian disease, where metformin works by decreasing the production of glucose in the liver, decreasing the intestinal absorption of glucose, increasing insulin sensitivity, and allowing better glucose uptake and utilization by the body. Alpha-lipoic acid is an antioxidant that helps protect cells from free radical damage. It helps improve insulin resistance and enhance glucose uptake by the body.

    How to use ALPHACYST M TABLET

    Take ALPHACYST M TABLET, preferably with meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition.

    Side Effects Of ALPHACYST M TABLET

    Common

    • nausea, vomiting, diarrhea, abdominal pain, and loss of appetite
    • changes in taste
    • skin rash
    • symptoms of low vitamin B12 levels in the blood may include extreme tiredness, a sore and red tongue (glossitis), pins and needles (paraesthesia), or pale or yellow skin

    Stop taking ALPHACYST M TABLET and consult your doctor immediately if you experience any of the following side effects:

    • The symptoms of lactic acidosis are vomiting, abdominal pain, muscle cramps, a general feeling of not being well with severe tiredness, difficulty breathing, reduced body temperature, and a slow heartbeat
    • Symptoms of low blood sugar levels such as headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery or light-headedness

    How To Manage Side Effects

    Diarrhea

    Drink lots of fluids, such as water or fruit juices, to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea. Contact your doctor if your diarrhea does not improve.

    Nausea And Vomiting

    Take ALPHACYST M TABLET with a meal. Stick to simple meals. Avoid eating oily or spicy food. Contact your doctor if your nausea and vomiting do not improve.

    Stomach Pain

    Rest and relax. Eat and drink slowly or try to have smaller and more frequent meals. Keep a heating pad on your stomach. Do not self-manage on your own, consult your doctor if the symptom does not improve on its own.

    Warning & Precautions

    Pregnancy

    Consult your doctor

    Inform your doctor if you are pregnant or planning to have a baby before taking this medicine.

    Breastfeeding

    Contraindicated

    ALPHACYST M TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking it.

    Driving and Using Machines

    Use with Caution

    Do not drive or operate any machinery if you have weakness, dizziness, increased sweating, a fast heartbeat, visual problems, or difficulty in concentration after taking ALPHACYST M TABLET.

    Alcohol

    Consult your doctor

    Avoid excessive consumption of alcohol, as it may increase the risk of lactic acidosis.

    Kidney

    Contraindicated

    ALPHACYST M TABLET is not recommended for use if you have severely reduced kidney function. Consult your doctor before taking it.

    Liver

    Contraindicated

    ALPHACYST M TABLET is not recommended for use if you have liver disease. Consult your doctor before taking it.

    Allergy

    Contraindicated

    Do not take ALPHACYST M TABLET if you are allergic to metformin, alpha-lipoic acid, or any of the other ingredients in this medicine.

    Heart Disease

    Contraindicated

    ALPHACYST M TABLET is not recommended for use if you are managed for acute heart failure, a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties. Consult your doctor before taking it.

    Use In Pediatrics

    Consult your doctor

    There is no information on the use of ALPHACYST M TABLET in children. Consult your doctor for advice.

    Use In Geriatrics

    Use with Caution

    ALPHACYST M TABLET should be used with caution only in elderly patients aged 65 years and older. Consult your doctor before taking it.

    Others

    ALPHACYST M TABLET is not recommended for use if you:

    • have uncontrolled diabetes mellitus with lactic acidosis, or ketoacidosis
    • have dehydration due to severe diarrhea and vomiting
    • have severe infections in the lungs and kidneys
    • are scheduled for lab testing
    • are planned for surgery

    Before taking ALPHACYST M TABLET, inform your doctor if you:

    • have thyroid disease
    • have vitamin B1 deficiency

    Interactions

    A. Drug-Drug interactions:

    Before taking ALPHACYST M TABLET, inform your doctor if you are taking any of the following medicines, such as:

    • sulphonylureas, insulin, and meglitinides (other medicines used to manage diabetes) Ex. glimepiride, repaglinide
    • medicines that increase urine production (diuretics) Ex. chlorothiazide
    • beta-2 agonists such as salbutamol or terbutaline (used to manage asthma)
    • corticosteroids (used to manage severe inflammation of the skin or asthma), Ex. dexamethasone
    • verapamil (medicine used to manage blood pressure)
    • rifampicin (a medicine used to manage tuberculosis)
    • cimetidine (a medicine used to manage stomach problems)
    • dolutegravir (a medicine used to manage viral infections)
    • ranolazine (medicine used to manage chest pain)
    • trimethoprim, neomycin, and aminosalicylic acid (medicine used to manage bacterial infections)
    • vandetanib, crizotinib, and olaparib (medicine used to manage cancer)
    • isavuconazole (a medicine used to manage fungal infections)
    • medicines used to manage pain and inflammation (NSAIDs and COX-2-inhibitors, such as ibuprofen and celecoxib)
    • certain medicines for the management of high blood pressure (ACE inhibitors and angiotensin II receptor antagonists) Ex. enalapril, candesartan
    • medicines to manage hypothyroidism Ex. levothyroxine

    Overdosage:

    If you or anyone else accidentally took more ALPHACYST M TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage may cause lactic acidosis, and symptoms include vomiting, abdominal pain with muscle cramps, a general feeling of not being well with severe tiredness, and difficulty breathing. Further symptoms include a reduced body temperature and heartbeat.

    Synopsis

    Drug :   Alpha lipoic acid and Metformin
    Pharmacological Category :   Antioxidants, Biguanides
    Therapeutic Indication :   Type II diabetes mellitus, Polycystic Ovarian Disease         
    Dosage Forms :   Tablet

    More Information

    • Keep ALPHACYST M TABLET out of the sight and reach of children
    • Store ALPHACYST M TABLET below 30°C

    FAQs About ALPHACYST M TABLET

    Q: What if I forget to take ALPHACYST M TABLET?

    A: If you forgot to take a dose of ALPHACYST M TABLET, take it as soon as you remember. However, if it is time for the next dose of ALPHACYST M TABLET, skip the missed dose and take the next one regularly. Do not take a double dose of ALPHACYST M TABLET to compensate for the missed ones.

    Q: Is ALPHACYST M TABLET safe in pregnancy?

    A: Inform your doctor if you are pregnant or planning to become pregnant before taking this medication.

    Q: Who should not take ALPHACYST M TABLET?

    A: ALPHACYST M TABLET is not recommended for use if you have severely reduced kidney function, liver disease, acute heart failure or a recent history of heart attack, or severe problems with blood circulation (such as shock) or have breathing difficulties, have uncontrolled diabetes mellitus with lactic acidosis or ketoacidosis, have dehydration due to severe diarrhea and vomiting, or have severe infections in the lungs and kidneys. Consult your doctor before taking it.

    Q: What are the side effects of taking ALPHACYST M TABLET?

    A: The most common side effects of taking ALPHACYST M TABLET are nausea, vomiting, diarrhea, abdominal pain, loss of appetite, changes in taste, and skin rash. Consult your doctor if any of the side effects worsen.

    Q: What should I avoid while taking ALPHACYST M TABLET?

    A: Avoid excessive consumption of alcohol while taking ALPHACYST M TABLET, as it may increase the risk of lactic acidosis.

    References

    1. KD. Tripathi. Insulin, Oral Antidiabetic Drugs and Glucagon. Essentials of medical pharmacology. Eight edition. 2019. Page – 299.

    2. Guarano A, Capozzi A, Cristodoro M, Di Simone N, Lello S. Alpha Lipoic Acid Efficacy in PCOS Treatment: What Is the Truth? Nutrients. 2023. [Accessed on 3rd January 2024] https://doi.org/10.3390/nu15143209

    3. A.S. Laganà, N. Monti, V. Fedeli, G. Gullo, M. Bizzarri. Does Alpha-lipoic acid improve effects on polycystic ovary syndrome? European review for Medical and Pharmacological Sciences.2022. [Accessed on 3rd January 2024] https://www.europeanreview.org/article/28116

    4. Brown & Burk UK Ltd. Electronic Medicines Compendium (EMC) [Revised in May 2022] [Accessed on 3rd January 2024] https://www.medicines.org.uk/emc/files/pil.10760.pdf

    5. Metmin A Tablet (Methylcobalamin+Alpha lipoic acid). Jenburkt Pharmaceuticals Ltd. [Accessed on 3rd January 2024] https://jenburkt.com/brands/metmin

    6. Drugs.com. Alpha lipoic acid. [Accessed on 3rd January 2024] https://www.drugs.com/mtm/alpha-lipoic-acid.html, https://www.drugs.com/npp/alpha-lipoic-acid.html

    Useful Diagnostic Tests

    • HbA1C, Also known as Glycated Hemoglobin, Glycosylated Hemoglobin
    • Blood Glucose Fasting (FBS)
    • Random Blood Sugar (RBS)
    • Post Prandial Blood Sugar (PPBS)
    • Insulin-Fasting
    • Insulin Postprandial (PP)
    • Vital Diabetes Care
    • Extended Diabetes Care
    • Advance Diabetes Care
    • Comprehensive Diabetes Care

    Author Details

    Written By Dr. N. Sai Swaroop - Pharm.D
    Reviewed For Accuracy By Dr. Jaya Prabakaran - MBBS, MD (Diabetology and Family Medicine)
    Last updated on 11 Jan 2024 | 12:17 PM(IST)
    Lab updated