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Introduction About ALBEFLUCO 150 TABLET
ALBEFLUCO 150 TABLET is used to manage various fungal infections such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis. Also, it manages fungal infections in immunocompromised patients considered at risk as a consequence of HIV infection or low white blood cell count after cytotoxic chemotherapy, radiotherapy or bone marrow transplant. It contains Fluconazole which belongs to the group of medicines called Anti-fungal agents. ALBEFLUCO 150 TABLET works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability.
Before taking ALBEFLUCO 150 TABLET, inform your doctor if you have liver, kidney or heart problems, abnormal levels of potassium, calcium, or magnesium in your blood, are prone to develop severe skin reactions or have a history of adrenal insufficiency. ALBEFLUCO 150 TABLET is not recommended for use in pregnant and breast-feeding women unless clearly advised by the doctor.
ALBEFLUCO 150 TABLET should be used with caution in children and adolescents (from birth to 17 years of age). ALBEFLUCO 150 TABLET should be used with caution in elderly patients particularly with renal impairment. The most common side effects of taking ALBEFLUCO 150 TABLET are headache, nausea, vomiting diarrhea, abdominal pain, and indigestion. Consult your doctor if any of the side effect gets worse.
Uses Of ALBEFLUCO 150 TABLET
- ALBEFLUCO 150 TABLET is used to manage various fungal infections such as systemic candidiasis, mucosal candidiasis, cryptococcosis and vaginal candidiasis
How ALBEFLUCO 150 TABLET Works
ALBEFLUCO 150 TABLET works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stops the fungal growth. This type of action is useful in managing and managing various fungal infections.
How to use ALBEFLUCO 150 TABLET
Take ALBEFLUCO 150 TABLET as advised by your physician. Swallow ALBEFLUCO 150 TABLET with a glass of water and do not chew or crush the medicine. The correct dose and duration for you will be decide by the doctor depending upon your age, body weight and type of infection.
Side Effects Of ALBEFLUCO 150 TABLET
Common
- headache
- nausea
- vomiting
- diarrhea
- abdominal pain
- indigestion
- acne
Uncommon
- seizures
- dizziness
- altered nerve sensation and taste
- skin rash with itching, abnormal odor from skin and dry skin
- abnormal changes in vision
- constipation
- flatulence
- dry mouth
- thirst, tiredness, body pain and fever
- weakness, general feeling of discomfort, rigor
- pharyngitis, herpes simplex viral infection
- loss of appetite
- back, muscle pain, muscle spasm
- renal pain
- head spinning sensation (vertigo)
- insomnia, and nervousness
- muscle overactivity (hypertonia)
- increased urine output
- abnormal or heavy vaginal bleeding, painful menses, vaginal discharge and disorder, uterine spasm, female sexual dysfunction
- hot flushes
- excess sleepiness
- deafness, increased blood pressure, low oxygen levels, intolerance to oral intake, inflamed and sore mouth (children)
Rare
- allergic reactions
- low white blood cells and platelet count
- hair loss
- damage to liver causing liver failure, hepatitis, and necrosis
- skin reactions (steven johnson syndrome and toxic epidermal necrolysis)
- shaking
- change in heart rate or rhythm
Stop taking ALBEFLUCO 150 TABLET and contact your doctor immediately if you experience any of the following side effects:
- sudden wheezing, difficulty in breathing or tightness in the chest, swelling of eyelids, face or lips, itching all over the body, reddening of the skin or itchy red spots
- skin rash that causes blistering in mouth and tongue
- signs of liver problems (tiredness, loss of appetite, vomiting and yellowing of the skin or whites of the eyes)
- signs of DRESS syndrome or drug hypersensitivity syndrome (widespread rash, high body temperature and enlarged lymph nodes)
How To Manage Side Effects
Diarrhea
Drink lot of fluids, such as water or fruit juice to keep yourself hydrated. Do not take any medicine on your own to manage diarrhea without consulting your doctor.
Dizziness Or Drowsiness
Lie down until dizziness is gone, then get up slowly. Move slowly and carefully, do not hurry. Get adequate rest. Drink plenty of water and other fluids. Avoid coffee, cigarettes, alcohol, and drugs. Consult your doctor if the symptom gets worse.
Headache
Drink ample amount of water and avoid skipping meals. Get adequate rest. Try to be relaxed and stress free. Apply pain relieving balm on your forehead if necessary. Consult your doctor if the symptom does not improve.
Nausea And Vomiting
Stick to simple meals while taking this medicine. Avoid eating oily rich, fried or spicy foods. Do not lie down or sleep immediately after eating. Consult your doctor if the symptom does not improve.
Stomach Pain
Try to take rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
Monitoring requiredALBEFLUCO 150 TABLET is not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking ALBEFLUCO 150 TABLET.
Breastfeeding
ContraindicatedALBEFLUCO 150 TABLET is not recommended for use in breastfeeding women after repeated use or after high dose of this medicine. You may continue breast-feeding after single dose of ALBEFLUCO 150 TABLET. Consult your doctor before taking ALBEFLUCO 150 TABLET.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if you experience dizziness or fits after taking ALBEFLUCO 150 TABLET.
Kidney
Use with CautionALBEFLUCO 150 TABLET should be used with caution in patients with kidney dysfunction. Consult your doctor before taking ALBEFLUCO 150 TABLET.
Liver
Use with CautionALBEFLUCO 150 TABLET should be used with caution in patients with liver dysfunction. Consult your doctor before taking ALBEFLUCO 150 TABLET.
Allergy
ContraindicatedALBEFLUCO 150 TABLET is not recommended for use if you are allergic to Fluconazole or other azole anti-fungals (such as itraconazole or posaconazole).
Heart Disease
Use with CautionALBEFLUCO 150 TABLET should be used with caution in patients with heart rhythm problems. Consult your doctor for advice before taking ALBEFLUCO 150 TABLET.
Use In Pediatrics
Use with CautionALBEFLUCO 150 TABLET should be used with caution in children and adolescents (from birth to 17 years of age). Consult your child’s doctor for advice before administration of ALBEFLUCO 150 TABLET to your child.
Use In Geriatrics
Use with CautionALBEFLUCO 150 TABLET should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking ALBEFLUCO 150 TABLET.
Others
ALBEFLUCO 150 TABLET is not recommended for use if you:
- have hereditary problems of galactose intolerance, Lapp lactase deficiency or glucose-galactose malabsorption
Before taking ALBEFLUCO 150 TABLET, inform your doctor if you:
- have abnormal levels of potassium, calcium, or magnesium in your blood
- are prone to develop severe skin reactions (itching, reddening of the skin or difficulty in breathing)
- have a history of adrenal insufficiency
- have no improvement in fungal infection
Interactions
A. Drug-Drug Interactions:
- Antidiabetics (Ex. glyburide, tolbutamide, glipizide, chlorpropamide)
- Anti-hypertensives (Ex. hydrochlorothiazide, nifedipine, isradipine, amlodipine, felodipine and losartan)
- Coumarin derivatives (Ex. warfarin)
- Immunosuppressants (Ex. cyclosporine, tacrolimus, sirolimus)
- Anti-TB medicines (Ex. Rifampicin or rifabutin)
- Anti-histamine (Ex. astemizole, terfenadine)
- Anticonvulsants (Ex. phenytoin or carbamazepine)
- Xanthine (Ex. Theophylline)
- Gastroprokinetic agent (Ex. cisapride)
- Anti-arrythmia agents (Ex. quinidine, amiodarone)
- Antidepressants (Ex. amitriptyline, nortriptyline)
- Diphenylbutylpiperidine (Ex. Pimozide)
- Antifungal agents (Ex. Amphotericin B, voriconazole)
- Antibiotics (Ex. Erythromycin)
- Alkylating agents (Ex. Cyclosphosphamide, vincristine or vinblastine)
- Alfentanil, fentanyl (used as general anesthetic)
- Phenanthrene class (Ex. Halofantrine)
- HMG-CoA reductase inhibitors (Ex. atorvastatin, simvastatin, and fluvastatin)
- COX-2 inhibitors (Ex. celecoxib, ibuprofen, and naproxen)
- Corticosteroid (Ex. Prednisone)
- Antivirals agents (Ex. saquinavir, zidovudine)
- Kinase (JAK) inhibitor (Ex. Tofacitinib)
- Quinolone (Ex. Ivacaftor)
- Ibrutinib (used for managing blood cancer)
- Benzodiazepines (Ex. midazolam, triazolam or similar medicines)
- Selective and potent inhibitor (Ex. olaparib)
- Opiate (narcotic) analgesics (Ex. Methadone)
Overdosage:
If you or anyone else accidentally takes too much of ALBEFLUCO 150 TABLET, consult your doctor immediately or visit the nearby hospital. Overdosage symptoms of ALBEFLUCO 150 TABLET are hearing, seeing, feeling and thinking things that are not real (hallucination and paranoid behaviour).
Synopsis
| Drug | : | Fluconazole |
| Pharmacological Category | : | Triazoles |
| Therapeutic Indication | : | Used to manage various fungal infections |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep ALBEFLUCO 150 TABLET out of reach of children
- Store ALBEFLUCO 150 TABLET at room temperature
FAQs About ALBEFLUCO 150 TABLET
Q: How does ALBEFLUCO 150 TABLET work?
A: ALBEFLUCO 150 TABLET works by stopping the action of an enzyme called ergosterol, which is an integral part of the fungal cell membrane to increase its cellular permeability. Thereby, making the cell membrane more permeable and stops the fungal growth. This type of action is useful in managing and managing various fungal infections.
Q: What if I forget to take a dose of ALBEFLUCO 150 TABLET?
A: If you have missed a dose of ALBEFLUCO 150 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose of ALBEFLUCO 150 TABLET to make up for the missed one as this may increase the chances of developing side effects.
Q: What are the common side effects of ALBEFLUCO 150 TABLET?
A: The common side effects of taking ALBEFLUCO 150 TABLET are headache, nausea, vomiting, diarrhea, abdominal pain, indigestion and acne. Consult your doctor if any of the symptom gets worse or does not improve over the time.
Q: Can ALBEFLUCO 150 TABLET be used in elderly patients?
A: ALBEFLUCO 150 TABLET should be used with caution in elderly patients particularly with renal impairment. Your doctor may adjust the dose depending upon kidney function. Consult your doctor for advice before taking ALBEFLUCO 150 TABLET.
Q: Is ALBEFLUCO 150 TABLET safe to use during pregnancy?
A: ALBEFLUCO 150 TABLET is not recommended for use during pregnancy unless clearly advised by the doctor. Consult your doctor before taking ALBEFLUCO 150 TABLET if you are pregnant or planning to get pregnant.
Q: Does ALBEFLUCO 150 TABLET work in 24 hours?
A: For a vaginal yeast infection, it may start to work within 24 hours. For other infections, it may take several days for you to notice improvement in your symptoms.
Q: Can I take ALBEFLUCO 150 TABLET daily?
A: The doctor will decide the dose depending on the type and severity of the infection. Take the exact dose for a specific duration. If you do not feel any improvement, inform your doctor but do not take it endlessly on your own without consulting a doctor.
Q: Is 3 days of ALBEFLUCO 150 TABLET enough?
A: If a single dose does not completely relieve symptoms, or the infection is severe. This medicine can be prescribed as three consecutive doses given three days apart. With this regimen it's expected that symptoms should improve within one to two weeks.
Q: Can I take ALBEFLUCO 150 TABLET at night?
A: One ALBEFLUCO 150 TABLET provides a full course of therapy sufficient to manage most vaginal yeast infections. It can be taken at any time of day or night, with or without food.
Q: What should I eat after taking ALBEFLUCO 150 TABLET?
A: Stick to simple meals and do not eat rich or spicy food. It might help to take your medicine after a meal or snack. If you're being sick, try small, frequent sips of water to avoid dehydration.
References
1. KD. Tripathi. Section, Antifungal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page-787.
2. Ameish Govindarajan; Karlyle G. Bistas; Curtis J. Ingold; Ayham Aboeed. NIH National Library of Medicine, National center for biotechnology information. June 2022. [Accessed on June 3rd, 2024] https://www.ncbi.nlm.nih.gov/books/NBK537158
3. Josilene Chaves Ruela Corrra & Herida Regina Nunes Salgado. Review of Fluconazole Properties and Analytical Methods for Its Determination, Critical Reviews in Analytical Chemistry. May 2011. [Accessed on June 3rd, 2024] https://www.tandfonline.com/doi/abs/10.1080/10408347.2011.557980?journalCode=batc20
4. Viatris Ltd. Fluconazole. [Revised in March 2022] [Accessed on June 3rd, 2024] https://www.medsafe.govt.nz/profs/datasheet/f/fluconazolecapmylan.pdf
5. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in April 2021] [Accessed on June 3rd, 2024] https://www.medicines.org.uk/emc/files/pil.6086.pdf
6. FDC limited. Zocon (Fluconazole tablets). [Revised in July 2022] [Accessed on June 3rd, 2024] http://fdcindia.com/PackageInsert/ZoconTablets.pdf
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Platelet Count/Thrombocyte Count
- Netmeds Immunity Care
- Full Body Checkup Essential
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