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Introduction About ACIVIR SYRUP
ACIVIR SYRUP contains Acyclovir which belongs to the group of medicines called Antivirals. It is used for the management of chickenpox, shingles, cold sores, genital herpes and other herpes simplex infections. It is also used to manage recurrent attacks and herpes infections in people with low immunity.
Chickenpox is an infection caused by the varicella-zoster virus and symptoms include an itchy rash with small, fluid-filled blisters. Shingles are defined as the reaction of the chicken pox virus in the body causing a painful rash. Cold sores, (a virus causing contagious sores, most often around the mouth or on the genitals), genital herpes (a common sexually transmitted infection caused by the herpes simplex virus) and symptoms include genital pain and sores, pain, itching and small sores.
Before taking ACIVIR SYRUP inform your doctor if you have kidney problems or dehydration. ACIVIR SYRUP should be used with caution by pregnant and breastfeeding women only if recommended by your doctor. ACIVIR SYRUP should be used with caution in children under 12 years of age and elderly over 65 years of age. The most common side effects of taking ACIVIR SYRUP are headache and dizziness. Contact your doctor if the symptom gets worse or persists.
Uses Of ACIVIR SYRUP
It is indicated for the management of the following viral infections:
- Manage chickenpox and shingles
- Manage cold sores, genital herpes and other herpes simplex infections
- Prevents recurrent attacks and herpes simplex infection in people with low immunity
How ACIVIR SYRUP Works
ACIVIR SYRUP works by killing or stopping the growth of viruses (herpes virus DNA). Acyclovir has a higher affinity for viral DNA cells than human DNA cells and incorporates into the viral DNA and causes DNA chain termination and inactivation, leading to the death of cells.
How to use ACIVIR SYRUP
Take ACIVIR SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending on your age, body weight and disease condition.
Side Effects Of ACIVIR SYRUP
Common
- headache, dizziness, nausea, vomiting, diarrhoea, stomach pain
- rash
- photosensitivity (skin reaction after exposure to light), itching
- feeling tired
- unexplained fever (high temperature), feeling faint, especially when standing up.
Uncommon
- itchy, redness of the skin, hive-like rash
- hair loss.
Rare
- shortness of breath
- fall in the number of white blood cells
- changes in results of blood, kidney and liver function test
- swelling of the face, lips, tongue or throat
- increase in liver enzymes
Stop taking ACIVIR SYRUP and contact your doctor immediately if you experience any of the following side effects:
- Kindly update like this
- allergic reaction symptoms such as skin rash, flaking skin, boils or sore lips and mouth, swelling of the face, lips, tongue, throat or other parts of your body. difficulty breathing, Shortness of breath, swallowing, sudden wheezing, fluttering or tightness of the chest or collapse
- signs of liver problems like hepatitis, hyperbilirubinemia, jaundice (yellowing of the skin and the whites of the eyes)
How To Manage Side Effects
Headache:
Rest and relax. Drink plenty of fluids such as water or ORS. Apply a pain-relieving balm on the head if necessary. Contact your doctor if the symptom does not improve.
Nausea or vomiting:
Take simple meals and do not eat rich or spicy food.
Diarrhoea:
Drink lots of fluids, such as water or fruit juice to keep you hydrated. Do not consume any medicine on your own without consulting your doctor.
Stomach pain:
Try to rest and relax. Try to have smaller meals but take them frequently. Keep a heating pad on your stomach. If the symptom does not improve, contact your doctor.
Dizziness:
If ACIVIR SYRUP makes you feel dizzy, take rest until you feel better. Do not drive or operate machines.
Itchy skin:
Try to use an unscented moisturiser. If the symptom does not improve, contact your doctor immediately.
Warning & Precautions
Pregnancy
ACIVIR SYRUP should be used with caution by pregnant women only if recommended by your doctor. Consult your doctor before taking ACIVIR SYRUP.
Breastfeeding
ACIVIR SYRUP should be used with caution by breastfeeding women only if recommended by your doctor Consult your doctor before taking ACIVIR SYRUP.
Driving and Using Machines
Do not drive or operate any machines if you feel dizzy, drowsiness or sleepy after taking ACIVIR SYRUP.
Kidney
ACIVIR SYRUP should be used with caution in patients with kidney problems. Consult your doctor before taking ACIVIR SYRUP.
Allergy
Do not take ACIVIR SYRUP if you are allergic to Acyclovir or valacyclovir or any of the other ingredients of this medicine.
Others
Before taking ACIVIR SYRUP, inform your doctor:
- dehydration
Use in pediatrics:
ACIVIR SYRUP should be used with caution in children under 12 years of age. Consult your doctor before taking ACIVIR SYRUP.
Use in geriatrics:
ACIVIR SYRUP should be used with caution in elderly patients (aged 65 years and above). Consult your doctor before taking ACIVIR SYRUP.
Interactions
A. Drug-Drug interactions:
Before receiving ACIVIR SYRUP, inform your doctor if you are taking any of the following medicine:
- probenecid ( used to manage gout)
- cimetidine (used to manage stomach ulcers)
- drugs acting on the immune system (Ex. mycophenolate mofetil, cyclosporine and tacrolimus)
Overdosage:
If you or anyone else accidentally take too much of ACIVIR SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are coma, seizures, agitation and lethargy etc.
Synopsis
| Drug | : | Acyclovir |
| Pharmacological Category | : | Antivirals |
| Therapeutic Indication | : |
Chickenpox, shingles, cold sores, genital herpes and other herpes simplex virus infection |
| Dosage Forms | : |
Tablet, Suspension, Syrup, Infusion, Injection, Cream, Ointment, Eye- ointment |
More Information
- Keep ACIVIR SYRUP out of the sight and reach from children
- Store ACIVIR SYRUP below 25°C
FAQs About ACIVIR SYRUP
Can I use ACIVIR SYRUP in children?
Yes. ACIVIR SYRUP is used for the management of chickenpox and herpes simplex virus in children. Consult your doctor before taking ACIVIR SYRUP.
Can I take ACIVIR SYRUP with milk?
No. Taking ACIVIR SYRUP with milk may lead to unwanted effects. Consult your doctor before taking ACIVIR SYRUP.
Does ACIVIR SYRUP cause photosensitivity?
Yes. ACIVIR SYRUP can cause photosensitivity. However, it does not affect every individual. Stay out of the bright sun and use sun creams (SPF-15) when going outside. If the symptom does not improve, contact your doctor.
Can ACIVIR SYRUP cause acne?
No. ACIVIR SYRUP does not cause acne. However, if you experience any side effects after taking ACIVIR SYRUP, consult your doctor.
References
1. KD Tripathi. Antiviral drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 799.
2. Rosemont Pharmaceuticals Ltd. Electronic Medicines Compendium (EMC). [Revised in September 2020] [Accessed on 21st April 2022] https://www.medicines.org.uk/emc/files/pil.77.pdf
3. GlaxoSmithKline. U.S. Food & Drug Administration. [Revised in June 2005] [Accessed on 21st April 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/018828s030,020089s019,019909s020lbl.pdf
4. Hi-Tech Pharmacal Co., Inc, Acyclovir. [Revised on March 2022] [Accessed on 21st April 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=62bdcf22-51f3-4c81-9bd4-a2dc48bec580
5. Syri Limited t/a Thame Laboratories. Health Products Regulatory Authority (HPRA). [Revised in April 2021] [Accessed on 21st April 2022] http://www.hpra.ie/img/uploaded/swedocuments/7648f1e3-b556-4fea-85a8-54b78d7a386b.pdf
Useful Diagnostic Tests
- Herpes Simplex Virus 1 DNA PCR
- Herpes Simplex Virus 1 IgG
- Herpes Simplex Virus 2 DNA PCR
- Herpes Simplex Virus 2 IgG
- Herpes Simplex Virus 2 IgM
- Varicella Zoster IgG
- Varicella Zoster IgM
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