ACINUAL Tablet 10's

Introduction About ACINUAL TABLET

ACINUAL TABLET contains Bromelain, Papain, Rutoside, and Trypsin which belongs to the group of medicines called Plant derivatives, and Proteolytic enzyme. It is used in the management of inflammation associated with conditions like post-operative (wound after any surgical procedures which is characterised by pain and redness), and traumatic or injury conditions, rheumatic & degenerative conditions like osteoarthritis, and osteoporosis, strain, sprains, and sports injury, low back pain, and spondylopathies. Arthritis is the tenderness or swelling of one or more joints characterized by pain, stiffness, and reduced movements.

ACINUAL TABLET is not recommended for use in patients having liver, and kidney problems and any scheduled surgery. ACINUAL TABLET should be used with caution in patients having asthma. ACINUAL TABLET is not recommended for use during pregnancy and it should be used with caution in breastfeeding women. ACINUAL TABLET is generally not recommended for use in children who are at the age of breastfeeding.

The safety and efficacy of ACINUAL TABLET have not been establishes in children below 18 years of age. The most common side effects of taking ACINUAL TABLET are a burning sensation and constipation. Consult your doctor for advice if any of these worsen or don’t improve.

Uses Of ACINUAL TABLET

• Manage post-operative and traumatic or injury conditions
• Manage rheumatic & degenerative conditions like osteoarthritis, and osteoporosis
• Manage strain, sprains, and sports injury, low back pain, and spondylopathies

How ACINUAL TABLET Works

ACINUAL TABLET helps in managing inflammation associated with various conditions where Bromelain works by inhibiting the substances like prostaglandins, bradykinin and proinflammatory cytokines which are responsible for causing inflammation and thereby speed up the wound healing process.

Papain with its anti-inflammatory effect reduces fluid retention and swelling. Trypsin resolves the signs and symptoms of inflammation by removing the dead tissue cells at the site of trauma and helps in the formation of new tissue or skin growth. Rutoside is an antioxidant, it also restores the strength of blood vessel wall which decrease their ability to break down.

How to use ACINUAL TABLET

Take ACINUAL TABLET as advised by your physician. Swallow the medicine as a whole with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of ACINUAL TABLET for you depending upon your age, body weight and disease condition.

Side Effects Of ACINUAL TABLET

How To Manage Side Effects

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly.

Warning & Precautions

Pregnancy

Contraindicated

ACINUAL TABLET is not recommended for use during pregnancy. Consult with your physician.

Breastfeeding

Use with Caution

ACINUAL TABLET should be taken with caution in a breastfeeding women. Consult with your physician before taking it.

Kidney

Contraindicated

ACINUAL TABLET is not recommended for use in patients having kidney problems. Consult your doctor for advice.

Liver

Contraindicated

ACINUAL TABLET is not recommended for use in patients having liver problems. Consult your doctor for advice.

Allergy

Contraindicated

Do not take ACINUAL TABLET if you are allergic to Bromelain, Papain, Rutoside, Trypsin or latex or any other ingredients of this medicine.

Lungs

Use with Caution

ACINUAL TABLET should be taken with caution in patients having asthma. Consult your doctor for advice.

Use In Pediatrics

Contraindicated

ACINUAL TABLET is generally not recommended for use in children who are at the age of breastfeeding. The safety and efficacy of ACINUAL TABLET have not been established in children below 18 years of age. Consult your doctor before taking it.

Use In Geriatrics

Consult your doctor

There is no information available on the use of ACINUAL TABLET in elderly patients. Consult your doctor before taking it.

Interactions

A. Drug-Drug interactions:

Before taking ACINUAL TABLET, inform your doctor if you are taking any of the following medicine:

• medicines used to manage clotting of blood (Ex. heparin, warfarin, clopidogrel)
• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) like ibuprofen, naproxen and opioids like codeine (used to reduce pain)
• antibiotics like tetracycline, and amoxicillin (used to manage infections)
• chemotherapy drugs like 5-fluorouracil, vincristine (used in cancer management)
• ACE inhibitors like captopril, and lisinopril (used to maintain blood pressure)
• lorazepam, benzodiazepines like diazepam (medicines used to induce sleep)
• antidepressants like doxepin (used to reduce depression)
• barbiturates like phenobarbital (used to manage epilepsy or fits)

B. Drug - Food interaction:

Do not take ACINUAL TABLET if you are allergic to foods like pineapple, wheat, celery, fennel, carrot, grass pollen or cypress pollen. Consult your doctor before taking ACINUAL TABLET.

Overdosage:

If you or anyone else accidentally take too much of ACINUAL TABLET, consult your doctor immediately or visit the nearby hospital.

Synopsis

More Information

• Keep ACINUAL TABLET out of reach from children
• Store ACINUAL TABLET at room temperature

FAQs About ACINUAL TABLET

Q: What are the uses of ACINUAL TABLET?

A: ACINUAL TABLET is used in the management of inflammation associated with the following conditions:

• post-operative and traumatic or injury conditions
• rheumatic & degenerative conditions like osteoarthritis, and osteoporosis
• strain, sprains, and sports injury, low back pain, and spondylopathies

Q: Can ACINUAL TABLET be used in a pregnant woman?

A: ACINUAL TABLET is not recommended for use during pregnancy. ACINUAL TABLET should be used with caution in a breastfeeding woman. Consult with your physician.

Q: Is there any food restrictions while taking ACINUAL TABLET?

A: Do not take ACINUAL TABLET if you are allergic to foods like pineapple, wheat, celery, fennel, carrot, grass pollen or cypress pollen. Consult your doctor before taking ACINUAL TABLET.

Q: Does ACINUAL TABLET causes diarrhoea?

A: Yes, ACINUAL TABLET may cause diarrhoea. Eat plenty of fiber rich foods such as fresh fruits, vegetables, and cereals and drink plenty of water. Exercise more regularly.

Q: What precaution needs to be taken while taking ACINUAL TABLET?

A: ACINUAL TABLET is not recommended for use if any surgery has been scheduled for you. You should avoid taking it at least two weeks before the surgery. Consult your doctor before taking it.

References

1. KD Tripathi. Digestants. Drugs Affecting Coagulation, Bleeding and Thrombosis and Drug Affecting Blood and Blood Formation, Autacoids and Related Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 719. 661.

2. Arka Jyoti Chakraborty, Saikat Mitra, Trina E. Tallei, Abu Montakim Tareq, Firzan Nainu, Donatella Cicia, Kuldeep Dham, Talha Bin, Jesus Simal-Gandara and Raffaele Capasso. Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective. March 2021. [Accessed 15th September 2022] https://www.mdpi.com/2075-1729/11/4/317

3. Trypsin. ScienceDirect. 2014. [Accessed 15th September 2022] https://www.sciencedirect.com/topics/neuroscience/trypsin

4. Aditya Ganeshpurkar and Ajay K. Saluja. The Pharmacological Potential of Rutin. National Library of Medicine, National center for biotechnology information. PubMed Central. February 2017. [Accessed 15th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355559/

5. Papin. ScienceDirect. 2019. [Accessed 15th September 2022] https://www.sciencedirect.com/topics/earth-and-planetary-sciences/papain

6. Bromelain. ScienceDirect. [Accessed 15th September 2022] https://www.sciencedirect.com/topics/neuroscience/bromelain

7. Acinual Tablet. Viilbery Healthcare Pvt Ltd. [Accessed 15th September 2022] https://viilbery.com/products/wound-healing/acinual-tablet.html#parentVerticalTab5

Author Details

Written By Dr. Dhivakaran R - BDS

Reviewed For Accuracy By Dr. Srikar Modepu - MBBS, MD (Diabetology)

Last updated on 04 Mar 2023 | 06:15 PM(IST)