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Introduction About ACIBRO 100MG SYRUP
ACIBRO 100MG SYRUP contains Acebrophylline which belongs to the group of medicines called Anti-asthmatic drugs. It is used in the management of asthma and chronic obstructive pulmonary disease (COPD). It can also be used to manage inflammation of the airways (such as bronchitis)
ACIBRO 100MG SYRUP is suitable for use both in adults and in children (aged 6 years or above). Before taking ACIBRO 100MG SYRUP inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have fits, stomach ulcers, viral infections, hypertension or hyperthyroidism as a precaution.
ACIBRO 100MG SYRUP is not recommended for use in pregnant women. It should be used in breastfeeding women only if it is considered necessary by the physician.
The most common side effects of taking ACIBRO 100MG SYRUP are epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation. Consult your doctor if any of these side effects trouble you.
Uses Of ACIBRO 100MG SYRUP
It is used in adults and in children (aged 6 years or above) to manage and prevent:
- Asthma & COPD
- Bronchitis (inflammation of the airways)
How ACIBRO 100MG SYRUP Works
ACIBRO 100MG SYRUP is a bronchodilator with anti-inflammatory properties. It blocks the release of certain chemicals (such as phosphodiesterase) in the respiratory tract that triggers airway inflammation, swelling and narrowing. As a result, it widens the airways, and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
How to use ACIBRO 100MG SYRUP
Take ACIBRO 100MG SYRUP as advised by your physician. Shake the medicine well before use. Measure the required quantity of the medicine in a measuring cup and consume it immediately.
Your doctor will decide the correct dose and duration of therapy depending upon your age, body weight and disease condition.
Do not stop taking ACIBRO 100MG SYRUP once your symptoms subside without consulting your doctor.
Side Effects Of ACIBRO 100MG SYRUP
Common
- stomach pain or discomfort, heartburn, loss of appetite
- transient nausea, dizziness
- vomiting, diarrhoea, constipation
- drowsiness
- skin rash or itching
- breathing difficulties
- nasal inflammation
Rare
- headache
- numbness of arm and legs
- lack of sleep
- fast heart rate
- high or low blood pressure
- sugar in urine
- increased blood sugar levels
How To Manage Side Effects
Nausea and Vomiting
Take ACIBRO 100MG SYRUP with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your symptom worsens.
Dizziness:
Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Warning & Precautions
Pregnancy
ACIBRO 100MG SYRUP is not recommended for use in pregnancy. Therefore, consult your doctor before taking it.
Breastfeeding
It is not known whether ACIBRO 100MG SYRUP can pass through breast milk. Therefore, it should be used in breastfeeding women only if considered necessary by the physician.
Driving and Using Machines
ACIBRO 100MG SYRUP usually does not affect your ability to drive or operate any machinery. However, do not drive or handle any heavy tools or machines if you feel dizzy or drowsy after taking ACIBRO 100MG SYRUP.
Kidney
ACIBRO 100MG SYRUP is not recommended for use in patients with severe kidney problems. It should be used with caution in patients with other kidney problems. Therefore, consult your doctor before taking it.
Liver
ACIBRO 100MG SYRUP is not recommended for use in patients with severe liver problems. It should be used with caution in patients with hepatic dysfunction. Therefore, consult your doctor before taking it.
Allergy
Do not take ACIBRO 100MG SYRUP if you are allergic to Acebrophylline or to any other methylxanthines (such as theophylline, doxophylline).
Heart Disease
ACIBRO 100MG SYRUP is not recommended for use in patients suffering from myocardial infarction or arrythmias. It should be used with caution in patients with heart failure or any other heart problems. Therefore, consult your doctor before taking it.
Others
ACIBRO 100MG SYRUP is not recommended for use if you:
- have hypotension (low blood pressure)
- have fluid and electrolyte imbalance
Before taking ACIBRO 100MG SYRUP, inform your doctor if you:
- have chronic alcoholism (addiction to alcohol)
- have any viral infections
- have an over-active thyroid gland
- have hypertension (high blood pressure)
- have ulcers in the stomach and/or intestines
- have fits (seizures)
Use in paediatrics:
ACIBRO 100MG SYRUP can be used in children and adolescents (aged between 6-18 years) if prescribed by the physician. Therefore, consult your doctor before taking it.
Use in geriatrics:
ACIBRO 100MG SYRUP should be used with caution in the elderly patients. Therefore, consult your doctor before taking it.
Interactions
A. Drug - Drug interactions:
Before taking ACIBRO 100MG SYRUP, inform your doctor if you are taking any of the following medicines such as:
- allopurinol (a medicine used to manage gout)
- cimetidine (a medicine used to manage stomach ulcers)
- medicines used to manage bacterial infections (such as ciprofloxacin, erythromycin, doxycycline, amoxicillin)
- corticosteroids (used to manage pain and inflammation) such as prednisolone
- diltiazem, verapamil (a medicine used to manage heart problems)
- frusemide (a medicine used to reduce edema and blood pressure by increasing urine output)
- isoprenaline (a medicine used to manage slow heart rate)
- oral contraceptives (birth control pills) such as ethinylestradiol
- thiabendazole (a medicine used to manage worm infections)
Overdosage:
If you or anyone else accidentally took more ACIBRO 100MG SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose might include nausea, vomiting, upper stomach pain, restlessness, fits, fast heart rate and hyperactivity.
Synopsis
| Drug | : | Acebrophylline |
| Pharmacological Category | : | Methylxanthines |
| Therapeutic Indication | : | Asthma, COPD, Bronchitis |
| Dosage Forms | : | Tablet, Capsule, Powder, Syrup |
More Information
- Keep ACIBRO 100MG SYRUP out of reach of children
- Store ACIBRO 100MG SYRUP at room temperature
FAQs About ACIBRO 100MG SYRUP
Q: How ACIBRO 100MG SYRUP works?
A: ACIBRO 100MG SYRUP widens the airways and reduces airway inflammation. It also loosens the mucus accumulated in the airways which allows the air to pass through more freely through the airways and makes breathing easier.
Q: What is the use of ACIBRO 100MG SYRUP?
A: ACIBRO 100MG SYRUP is used to manage asthma, COPD and bronchitis (inflammation of the airways).
Q: Can I take ACIBRO 100MG SYRUP daily?
A: ACIBRO 100MG SYRUP is generally prescribed as one or two doses per day. However, your doctor will decide the number of doses per day depending upon your age, body weight and disease condition.
Q: How long does it take for ACIBRO 100MG SYRUP to start working?
A: ACIBRO 100MG SYRUP may start working within 2 hours of oral administration. However, it may take 2 weeks for ACIBRO 100MG SYRUP to show improvements in your condition. Therefore, take ACIBRO 100MG SYRUP regularly as informed by your doctor without fail to achieve better results.
Q: Is ACIBRO 100MG SYRUP effective?
A: Yes. ACIBRO 100MG SYRUP effectively controls the symptoms of asthma, COPD and bronchitis, by blocking the release of certain chemicals (phosphodiesterase) in the respiratory tract that triggers the allergic and inflammatory response. It also loosens the mucus and manages the narrowing of the airway tract which makes breathing easier.
Q: What will happen if I consume a high dose of ACIBRO 100MG SYRUP than prescribed by my doctor?
A: Do not consume a higher dose of ACIBRO 100MG SYRUP than the one prescribed by your doctor, as it may lead to unwanted side effects. Your doctor will decide the correct dose for you, depending on your age and disease condition. If the prescribed dose, is not working for you, consult your doctor for advice.
Q: Is ACIBRO 100MG SYRUP safe?
A: ACIBRO 100MG SYRUP is considered safe at doses prescribed by the physician. However, it may cause few side effects such as epigastric pain, stomach discomfort, nausea, vomiting, dizziness, drowsiness, diarrhea and constipation in some individuals. Consult your doctor if any of these side effects trouble you.
Q: What should I do if I forgot to take a dose of ACIBRO 100MG SYRUP?
A: If you forgot to take a dose of ACIBRO 100MG SYRUP, take it as soon as possible. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of ACIBRO 100MG SYRUP to compensate the missed dose.
Q: Will taking a higher dose of ACIBRO 100MG SYRUP be more effective?
A: No. Do not take a higher dose of ACIBRO 100MG SYRUP than prescribed by your doctor, as it could lead to toxicity. Always consume the dose prescribed by your doctor. If you feel that the prescribed dose is not working for you, consult your doctor for advice.
Q: Can the use of ACIBRO 100MG SYRUP make me feel dizzy?
A: ACIBRO 100MG SYRUP may cause dizziness in some individuals. If you experience dizziness, try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines completely while you are feeling dizzy. Do not consume excessive alcohol, as it could aggravate your dizziness. Consult your doctor if your dizziness worsens.
Q: I’m pregnant. Can I take ACIBRO 100MG SYRUP?
A: ACIBRO 100MG SYRUP is generally not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Q: Can ACIBRO 100MG SYRUP be used in children?
A: ACIBRO 100MG SYRUP can be used in children and adolescents (aged between 6-18 years) if prescribed by the physician. Therefore, consult your doctor before taking it.
Q: Can ACIBRO 100MG SYRUP make you sleepy?
A: Yes. This medicine may make you feel sleepy or drowsy. Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.
Q: Can ACIBRO 100MG SYRUP be used on an asthma attack?
A: No. ACIBRO 100MG SYRUP is only used to manage or manage the symptoms of asthma. If your asthma or breathing gets worse suddenly, contact your doctor immediately or go to the hospital straight away to avoid further exacerbation of the attack. Meanwhile use a fast-acting rescue inhaler along with ACIBRO 100MG SYRUP.
Q: Can I stop using ACIBRO 100MG SYRUP once my symptoms subside?
A: No. Continue to use ACIBRO 100MG SYRUP as long as your doctor prescribes it to you. Do not stop using this medicine or reduce the dose suddenly without consulting your doctor as it may make it less effective.
References
1. KD. Tripathi. Drugs for Cough and Bronchial Asthma. Essentials of medical pharmacology. Seventh edition. 2013. Page – 224.
2. Sumit Roy Tapadar, Maumita Das, Arunabha Datta Chaudhuri, Santanu Basak, and Anil Baran Singha Mahapatra. The Effect of Acebrophylline vs Sustained Release Theophylline in Patients of COPD- A Comparative Study. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2014. [Accessed on 9th January 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225926/
3. Cipla Ltd. Mucophylin Capsules (Acebrophylline). [Revised in November 2013] [Accessed on 9th January 2023] https://www.ciplamed.com/print-product-pdf/24147
4. Central Drugs Standard Control Organization. Acebrophylline Syrup. January and March 2009. [Accessed on 9th January 2023] https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadApprovalMarketingFDC/LIST%20OF%20APPROVED%20DRUG%20FROM%2001-01-2008%20to%2031-12-2008.pdf

