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Introduction About ABSENZ SYRUP
ABSENZ SYRUP contains Ethosuximide which belongs to a group of medicines called Anti-epileptics. It is used in the management of epilepsy. It controls brief, sudden loss of consciousness (absence seizures or petit mal seizures) and uncontrolled jerking movements (myoclonic seizure).
Epilepsy is a condition of central nervous system in which the brain activity becomes abnormal causing seizures (fits), episodes of unusual behaviour, sensations and loss of awareness.
Prior to the management with ABSENZ SYRUP your doctor might ask you to take several diagnostic tests to better assess your condition.
Before taking ABSENZ SYRUP inform your doctor if you have porphyria (metabolism disorder), liver or kidney disease.
ABSENZ SYRUP should be taken with doctor’s consultation in pregnant women. It is not recommended to take ABSENZ SYRUP in breast feeding women. Consult your doctor before taking the medicine.
The most common side effects of taking ABSENZ SYRUP are decreased appetite, headache, difficulty in controlling movements, dizziness, drowsiness, stomachache and cramps, feeling sick, vomiting, skin rash. Consult your doctor if any of these side effects worsen.
Uses Of ABSENZ SYRUP
- Used to manage epilepsy (fits)
How ABSENZ SYRUP Works
ABSENZ SYRUP works by acting on the central nervous system and blocks the abnormal activity of nerve cells and manages the unusual build-up of electrical signals in the brain.
How to use ABSENZ SYRUP
Take ABSENZ SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Side Effects Of ABSENZ SYRUP
Common
- decreased appetite
- headache
- unsteadiness
- difficulty in controlling movements
- dizziness
- drowsiness
- stomachache, cramps
- vomiting
- skin rash including measles-like reactions
Uncommon
- aggressive behaviour
- nightmares
- depression
- suicidal thoughts
- psychotic disorder
- disturbance to sleep patterns
- sluggishness
- inability to concentrate
- short sightedness
- hiccups
- diarrhoea
- enlarged gums, swollen tongue
- blood in the urine
- vaginal bleeding
- fatigue, irritability
- weight loss
- feelings of persecution
- hyperactivity
Rare
Stop taking ABSENZ SYRUP and contact your doctor immediately if you experience any of the following side effects:
- red patches on the body, the patches are target-like circular, often with central blisters, skin peeling, ulcers in mouth, throat, nose, genitals and eyes (stevens-johnson syndrome)
- widespread rash, raised body temperature and enlarged lymph nodes (drug reaction with eosinophilia and systemic symptoms)
- pain and inflammation of the joints with fever and rash (systemic lupus erythematosus)
- bruising or bleeding more easily, fever, paleness or severe sore throat, mouth ulcers, fatigue, repeated infections
- increase in the number of fits (tonic-clonic seizures)
How To Manage Side Effects
Headache:
Rest and relax. Apply a pain-relieving bam on your forehead. If the symptom does not improve, contact your doctor.
Drowsiness:
Take adequate sleep. Do not involve in rigorous activities. Do not interfere with your sleep cycle. Talk to your doctor if the symptom doesn’t improve.
Diarrhea:
Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor.
Stomach pain:
Try to rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. If the symptom does not improve, contact your doctor.
Warning & Precautions
Pregnancy
ABSENZ SYRUP should be taken with caution in pregnant women unless considered clearly necessary. Consult your doctor before taking it.
Breastfeeding
ABSENZ SYRUP is not recommended for use in breastfeeding women. Consult your doctor before taking it.
Driving and Using Machines
Do not drive or operate any machines if you feel drowsy after taking ABSENZ SYRUP.
Kidney
ABSENZ SYRUP should be taken with caution in patients with kidney disease. Consult your doctor before taking.
Liver
ABSENZ SYRUP should be taken with caution in patients with liver disease. Consult your doctor before taking.
Allergy
Do not take ABSENZ SYRUP if you are allergic to Ethosuximide or any other ingredients of this medicine.
Others
ABSENZ SYRUP is not recommended for use if you:
- have porphyria
- have blood disorder
Use in Pediatrics:
Your doctor will prescribe the right dose of ABSENZ SYRUP depending on your child’s age, body weight and disease condition. Consult your doctor before taking.
Use in Geriatrics:
Your doctor will decide the right dose depends on your age, body weight and disease condition. Consult your doctor before taking.
Interactions
A. Drug - Drug Interactions:
Before taking ABSENZ SYRUP inform your doctor if you are taking any of the following medicine:
- medicine used for certain types of infections (Ex. isoniazid)
- medicines used for epilepsy (Ex. phenytoin, carbamazepine, sodium valproate and valproic acid)
Overdosage:
If you or anyone else accidentally takes too much of ABSENZ SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose are extreme drowsiness and confusion.
Synopsis
| Drug | : | Ethosuximide |
| Pharmacological Category | : | Anti-epileptics |
| Therapeutic Indication | : | Epilepsy |
| Dosage Forms | : | Syrup |
More Information
- Keep ABSENZ SYRUP out of reach of children
- Store below 30°C
FAQs About ABSENZ SYRUP
What is ABSENZ SYRUP used for?
ABSENZ SYRUP contains Ethosuximide which belongs group of medicines called anti-epileptics. It is used to control epilepsy(fits) in children and adults and is considered as the drug of choice in the management of absence seizures (or petit-mal seizures). Consult your doctor regarding the severity of the disease condition for correct dosage and duration of ABSENZ SYRUP.
What if I forget to take ABSENZ SYRUP?
If you miss your ABSENZ SYRUP dose at the usual time, take it immediately and then return to your routine dosing time. If it is almost time for your next dose, just skip the missed dose and take your next dose at the regular time of dosage. Do not take two doses of ABSENZ SYRUP at the same time to make up for the missed dose.
Can I stop taking ABSENZ SYRUP if I feel better?
Do not alter or discontinue the daily dose of ABSENZ SYRUP after feeling better without consulting your doctor as it may lead to seizures. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.
Is ABSENZ SYRUP safe to use in pregnancy or breast feeding?
ABSENZ SYRUP must be used with caution in pregnant and in women who are planning to become pregnant. It is not recommended for use in breast feeding women. Consult your doctor before taking it.
Can ABSENZ SYRUP cause headache?
Yes, headache is one of the most common side effects of taking ABSENZ SYRUP. In case if you are experiencing a headache after taking ABSENZ SYRUP, try to rest and relax. Keep drinking plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol. Consult your doctor if headache persists for a long time.
Can I drive a car after taking ABSENZ SYRUP?
It’s advisable not to drive as ABSENZ SYRUP may cause drowsiness or dizziness which could change your reactivity and may impair your reactions while driving. Consult your doctor before using ABSENZ SYRUP.
Can I take other epileptic medicines with ABSENZ SYRUP?
It is advisable not use other epileptic drugs (such as carbamazepine, phenytoin, sodium valproate and valproic acid) with ABSENZ SYRUP unless advised by the doctor. Your doctor may need to test the amount of these medicines in your blood to help decide if any of these medicines are affecting your management.
References
1. KD. Tripathi. Drugs Acting on Central Nervous System. Seventh edition. 2013. Page – 416.
2. Brian Hanrahan; Robert P. Carson. Ethosuximide. NIH. National Library of Medicine, National center for biotechnology information. Dec 2021. [Accessed on 29th April 2022] https://www.ncbi.nlm.nih.gov/books/NBK544244/
3. Delpharm Bladel B.V. Electronic Medicines Compendium (EMC). [Revised in Sept 2021] [Accessed 28th April 2022] https://www.medicines.org.uk/emc/files/pil.10195.pdf
4. Medlineplus. [Accessed 28th April 2022] https://medlineplus.gov/druginfo/meds/a682327.html#:~:text=Ethosuximide%20is%20used%20to%20control,class%20of%20medications%20called%20anticonvulsants.
5. Sciencedirect.com. [Accessed 28th April 2022] https://www.sciencedirect.com/topics/medicine-and-dentistry/ethosuximide#:~:text=Childhood%20Absence%20Epilepsy,risk%20of%20serious%20adverse%20effects.
6. Drugbank. com. [Accessed 28th April 2022] https://go.drugbank.com/drugs/DB00593
Useful Diagnostic Tests
- EEG (Electroencephalogram)
- CBC (Complete Blood Count)
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