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Introduction About ABACAVEX 300 TABLET
ABACAVEX 300 TABLET contains Abacavir which belongs to the group of medicines called Anti-viral agents. It is used to manage HIV infection. HIV (Human Immunodeficiency Virus) infection is a viral infection that damages our immune system and weakens our body’s ability to fight against various other opportunistic infections.
Do not take ABACAVEX 300 TABLET if you are allergic to abacavir. Before taking ABACAVEX 300 TABLET inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have diabetes, high blood pressure or high blood cholesterol levels as a precaution.
While undergoing therapy with ABACAVEX 300 TABLET, it is important for you to follow certain measures to manage the spread of infections to the other people (such as avoid having unprotected sexual intercourse or sharing needles or personal items like toothbrush, razors etc with other people). ABACAVEX 300 TABLET is not recommended for use in pregnant or breastfeeding women.
ABACAVEX 300 TABLET cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level. During management with ABACAVEX 300 TABLET your doctor will closely monitor your body weight, blood cholesterol levels and blood sugar levels to reduce the risk of unwanted side effects.
The most common side effects of taking ABACAVEX 300 TABLET are fever, skin rash, nausea, stomach pain, headache and tiredness. Consult your doctor if any of these side effects worsens.
Uses Of ABACAVEX 300 TABLET
- Manage HIV infection
How ABACAVEX 300 TABLET Works
ABACAVEX 300 TABLET is an anti-viral medicine. It controls the multiplication of viral cell within the body, by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. It can also improve immunity in the affected patients by increasing the numbers of certain types of white blood cells (CD4) in the body which is required to fight against various infections.
How to use ABACAVEX 300 TABLET
Take ABACAVEX 300 TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABACAVEX 300 TABLET can be taken with or without meals.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection. Do not stop taking ABACAVEX 300 TABLET without consulting your doctor as it may reduce its effectiveness.
Side Effects Of ABACAVEX 300 TABLET
Common
- headache, tiredness
- nausea, vomiting, diarrhoea
- fever, skin rash
- stomach pain
- loss of appetite
- joint pain, muscle pain
Rare
Stop taking ABACAVEX 300 TABLET and contact your doctor immediately if you experience any of the following side effects:
- signs of allergic reactions (such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck, difficulty in breathing, mouth ulcers, occasional headaches, inflammation of the eye, low blood pressure, sense of tingling or numbness of hands or feet)
How To Manage Side Effects
Diarrhea
Drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. Do not consume any medicine on your own without consulting your doctor. If your diarrhea worsens, contact your doctor immediately.
Headache
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Nausea And Vomiting
Take ABACAVEX 300 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if your nausea worsens.
Warning & Precautions
Pregnancy
ContraindicatedABACAVEX 300 TABLET is not recommended for use in pregnant women. Therefore, consult your doctor before taking it.
Breastfeeding
Consult your doctorBreastfeeding should be discontinued in mothers infected with HIV infection. Therefore, consult your doctor for advice.
Driving and Using Machines
Use with CautionDo not drive or operate any machines if your ability is affected by ABACAVEX 300 TABLET.
Alcohol
Use with CautionAvoid consumption of alcohol while taking ABACAVEX 300 TABLET.
Kidney
Use with CautionABACAVEX 300 TABLET should be used with caution in patients with severe kidney problems. Therefore, consult your doctor before taking it.
Liver
Use with CautionABACAVEX 300 TABLET should be used with caution in patients with moderate to severe liver diseases (including previous history of Hepatitis B or C infection). Therefore, consult your doctor before taking it.
Allergy
ContraindicatedDo not take ABACAVEX 300 TABLET if you are allergic to abacavir.
Heart Disease
Use with CautionABACAVEX 300 TABLET should be used with caution in patients with heart problems. Therefore, consult your doctor before taking it.
Use In Pediatrics
Consult your doctorABACAVEX 300 TABLET can be used in children who weigh at least 14 kg or more if prescribed by the physician. Therefore, consult your doctor before taking it.
Use In Geriatrics
Use with CautionABACAVEX 300 TABLET should be used with caution in elderly people. Therefore, consult your doctor before taking it.
Others
ABACAVEX 300 TABLET is not recommended for use if you:
- have a genetic problem (called as HLA-B*5701 allele)
Before taking ABACAVEX 300 TABLET inform your doctor if you:
- are overweight
- have diabetes
- have high blood cholesterol levels
- have high blood pressure
- smoke
Interactions
A. Drug-Drug interactions:
Before taking ABACAVEX 300 TABLET inform your doctor if you are taking any of the following medicines such as:
- phenytoin (a medicine used to manage epilepsy)
- methadone (a medicine used for pain relief)
- riociguat (a medicine used to manage increased pressure in the lungs)
Overdosage:
If you or anyone else accidentally took more ABACAVEX 300 TABLET, consult your doctor immediately.
Synopsis
| Drug | : | Abacavir |
| Pharmacological Category | : | Nucleoside Reverse transcriptase inhibitors |
| Therapeutic Indication | : | HIV infection |
| Dosage Forms | : | Tablet |
More Information
Storage
- Keep ABACAVEX 300 TABLET out of reach of children
- Store ABACAVEX 300 TABLET at room temperature
FAQs About ABACAVEX 300 TABLET
Q: What is ABACAVEX 300 TABLET?
A: ABACAVEX 300 TABLET is an antiviral medicine used to manage HIV infection. It acts by reducing the multiplication of viral cells within the body. It also improves immunity by increasing the numbers of certain white blood cells (CD4) in the body which is required to fight against various infections.
Q: Is ABACAVEX 300 TABLET safe?
A: ABACAVEX 300 TABLET is safe at doses prescribed by the physician.
Q: How does ABACAVEX 300 TABLET work in our body?
A: ABACAVEX 300 TABLET acts by blocking the actions of certain viral enzymes (HIV-reverse transcriptase) that is required for the viral cell to grow and multiply. This reduces multiplication of viral cells. It can also offer immunity in the affected patients by increasing the number of certain types of white blood cells (CD4) in the body which is required to fight against various infection.
Q: What are the signs of hypersensitive reaction that is possible after taking ABACAVEX 300 TABLET?
A: ABACAVEX 300 TABLET may cause certain signs of infections or hypersensitive reactions such as skin rash, fever, accompanied with sore throat, cough, nausea, vomiting, stomach pain, diarrhea, tiredness, joint pain, muscle pain, swelling of the neck or difficulty in breathing. If you experience any of these side effects, stop taking ABACAVEX 300 TABLET and consult your doctor immediately.
Q: Can I stop taking ABACAVEX 300 TABLET if I feel unwell?
A: No. Do not stop taking ABACAVEX 300 TABLET without consulting your doctor. Take ABACAVEX 300 TABLET regularly, because if you miss a dose of ABACAVEX 300 TABLET or take it at irregular intervals, you may experience some unpleasant reactions. If you wish to discontinue ABACAVEX 300 TABLET due to unpleasant symptoms, consult your doctor for advice.
Q: What to do if I forget to take a dose of ABACAVEX 300 TABLET?
A: If you miss a dose of ABACAVEX 300 TABLET take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular time. Do not take a double dose of ABACAVEX 300 TABLET to compensate the missed dose.
Q: Can ABACAVEX 300 TABLET manage HIV completely?
A: No. ABACAVEX 300 TABLET cannot not manage HIV infection completely. It can reduce only the number of viral cells present in the body and maintains them at a lower level.
Q: What are the precautions to be followed while taking ABACAVEX 300 TABLET?
A: Before taking ABACAVEX 300 TABLET inform your doctor if you have diabetes or any liver (hepatitis C or B infection), kidney or heart problems. Regularly visit your doctor and take all the blood tests recommended for you. Consult your doctor before taking ABACAVEX 300 TABLET if you are pregnant or breastfeeding. Do not stop taking ABACAVEX 300 TABLET without consulting your doctor. inform your doctor immediately if you experience any signs of allergic reactions after taking ABACAVEX 300 TABLET.
Q: Can ABACAVEX 300 TABLET be used in children?
A: ABACAVEX 300 TABLET can be used in children who weigh at least 14 kg or more if prescribed by the physician. Therefore, consult your doctor before taking it.
Q: How to take ABACAVEX 300 TABLET?
A: Take ABACAVEX 300 TABLET as directed by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. ABACAVEX 300 TABLET can be taken with or without meals. Continue to take ABACAVEX 300 TABLET regularly as advised by your physician for maximum benefits.
Q: Is ABACAVEX 300 TABLET safe in pregnancy?
A: ABACAVEX 300 TABLET is not recommended for use during pregnancy. It may affect the growth of the unborn baby. Therefore, consult your doctor before taking it.
Q: Can ABACAVEX 300 TABLET cause diarrhea?
A: Yes. Diarrhea is a common side effect of ABACAVEX 300 TABLET. Drink lots of fluids, such as water or fruit juice to keep yourself hydrated. Do not consume any medicine on your own without consulting your doctor. If you experience persistent diarrhea, consult your doctor.
References
1. KD. Tripathi. Antiviral Drugs. Essentials of Medical Pharmacology. 7th Edition. 2013. Page – 808.
2. Jared Vincent Fernandez; Ahmed Munir. Abacavir. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. May 2022. [Accessed on 13th August 2024] https://www.ncbi.nlm.nih.gov/books/NBK537117/
3. P S Hervey, C M Perry. Abacavir: a review of its clinical potential in patients with HIV infection. NIH. National Library of Medicine. National Center for Biotechnology Information. Pubmed.gov. August 2000. [Accessed on 13th August 2024] https://pubmed.ncbi.nlm.nih.gov/10983741/
4. Dr. Reddy’s Laboratories (UK) Ltd. Electronic Medicines Compendium (EMC). [Revised in December 2021] [Accessed on 13th August 2024] https://www.medicines.org.uk/emc/files/pil.10525.pdf
5. Cipla Ltd. Abamune Tablets. Ciplamed.com. [Revised in November 2018] [Accessed on 13th August 2024] https://www.ciplamed.com/product-index/abamune-tablets
Useful Diagnostic Tests
- Complete Blood Count (CBC)/ Hemogram
- Liver Function Test (LFT)
- Cd4 Absolute Count
- Hiv Preventive Package
- HIV 1&2 Antibodies
- HIV Viral Load (Quantitative) Test
- Western Blot For Hiv
- HIV-Dna Pcr - Qualitative
- HIV-Rna Pcr - Qualitative
- HIV Monitoring - I
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