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INTRODUCTION
ZOXAN EYE/EAR DROPS contains ciprofloxacin, which belongs to the group of medicines called fluoroquinolone antibiotics. It is used to treat bacterial infection of the eye or the ear in conditions such as corneal ulcers, chronic Suppurative otitis media, external otitis, malignant otitis externa, etc. Symptoms of an eye or ear infection may include red, watery eyes and bloodshot eyes, severe eye pain, pus or discharge and in severe cases can also lead to vision loss and blindness.
ZOXAN EYE/EAR DROPS is also used for the topical treatment of inflammatory ear infections such as Chronic Suppurative otitis media, external otitis, malignant otitis externa and perioperatively in chronic otitis media. This medicine is indicated for use in adults and children above 1 year.
ZOXAN EYE/EAR DROPS on prolonged use can cause an overgrowth of other non-susceptible organisms. Hence, it should be used only for the prescribed time as per your doctor. ZOXAN EYE/EAR DROPS should be used with caution during pregnancy and breastfeeding only if the potential benefit justifies the potential risk to the baby.
ZOXAN EYE/EAR DROPS is not recommended for use by children below 12 months (1 year) of age, including newborns without a doctor’s advice. The most common side effects of using ZOXAN EYE/EAR DROPS are redness, itching, irritation, pain, red eye, and double vision. Consult a doctor immediately if any of the symptoms worsen.
USES OF ZOXAN EYE/EAR DROPS
- Treats eye conditions such as corneal ulcers and superficial infections of the eye caused by bacteria in particular Pseudomonas aeruginosa and other gram-negative bacteria, which are resistant to usual treatments
- Treats inflammatory ear infections such as chronic suppurative otitis media, external otitis, malignant otitis externa and perioperatively in chronic otitis media in adults and children above 1 year
HOW ZOXAN EYE/EAR DROPS WORKS
ZOXAN EYE/EAR DROPS is an antibacterial agent that acts by inhibiting bacterial replication by targeting the essential enzyme (DNA gyrase) inside the bacteria. As a result, it treats and prevents bacterial infections involving the eye and the ear.
DIRECTIONS FOR USE
Always apply ZOXAN EYE/EAR DROPS as directed by your physician. It is for external use only. Wash your hands before applying them to the affected area. Do not wear contact lenses while using this medicine in the eye. Your doctor will prescribe the correct dose and duration according to your age and disease condition.
SIDE EFFECTS OF ZOXAN EYE/EAR DROPS
COMMON
- white deposit on the eye surface (cornea)
- ocular discomfort (stinging, burning, gritty feeling in the eye, irritation)
- redness of the eye
- bad taste/altered taste
UNCOMMON
- damage to the eye surface (cornea)
- sensitivity to light
- blurred vision
- swelling of the eye and eyelids
- pain
- dry eye
- itchiness
- eye discharge
- eyelid crusting
- eyelids scales
- eyelid redness
- poor vision
- watery eyes
- red eyes
- headache
- nausea
RARE
- damage to the eye
- inflammation
- double vision
- decreased eye sensation
- tired eyes
- stye (infection of the eyelashes)
- rhinitis (irritation in the nose, watery discharge)
- hypersensitivity
- dizziness
- ear pain
- inflammation inside the nose
- nasal sinus discharge
- diarrhoea
- abdominal pain
- skin inflammation/dermatitis
- tendon disorder
Stop using ZOXAN EYE/EAR DROPS and consult your doctor immediately if you experience any of the following side effects
- signs of allergic reaction such as skin rash, pain, swelling of face, hands, or feet, wheezing, difficulty in breathing, shortness of breath, nettle rash (severe and sudden onset of pinkish, itchy swelling of the skin)
- any inflammation or inflammatory condition
- white particles in your eyes
WARNING & PRECAUTIONS
PREGNANCY
ZOXAN EYE/EAR DROPS should be used during pregnancy only if the potential benefit justifies the potential risk to the developing baby. Consult your doctor before using ZOXAN EYE/EAR DROPS.
BREASTFEEDING
ZOXAN EYE/EAR DROPS should be used with caution in breastfeeding mothers due to the lack of safety data in topical use. Consult your doctor before using ZOXAN EYE/EAR DROPS.
DRIVING AND USING MACHINES
Do not drive or use machinery after using ZOXAN EYE/EAR DROPS as the medicine could temporarily blur or affect your vision.
ALLERGY
Do not use ZOXAN EYE/EAR DROPS if you are allergic to ciprofloxacin or other quinolone antibiotics or any other ingredients of this medicine.
OTHERS
ZOXAN EYE/EAR DROPS is not recommended for use if
- you are wearing contact lenses during the treatment of the eye
Use in Pediatrics:
ZOXAN EYE/EAR DROPS is generally not recommended for use in children below 1 year of age (12 months) with a doctor’s advice. Consult your doctor before using ZOXAN EYE/EAR DROPS.
Use in Geriatrics:
ZOXAN EYE/EAR DROPS should be used with caution in elderly patients. Consult your doctor before using ZOXAN EYE/EAR DROPS.
INTERACTIONS
A. Drug-Drug interactions:
Before using ZOXAN EYE/EAR DROPS, inform your doctor if you are taking any of the following medicine:
- medicines used to treat pain and inflammation, asthma or skin problems such as corticosteroids (Ex. cortisone, prednisone, prednisolone, methylprednisolone, dexamethasone, betamethasone, hydrocortisone)
Overdosage:
If you or anyone else accidentally put too many drops of ZOXAN EYE/EAR DROPS into the eyes, immediately rinse your eyes with warm water. Consult a doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Ciprofloxacin |
| Pharmacological Category | : | Fluoroquinolone antibiotics |
| Therapeutic Indication | : | Ear or eye inflammatory conditions |
| Dosage Forms | : | Tablets, Injections, Infusions, Drops, Dry Syrup, Eye ointment, Eye drops, Ointment, Ear drops |
MORE INFORMATION
- Keep out of reach from children
- Store at room temperature
FAQs ABOUT ZOXAN EYE/EAR DROPS
Can I wear contact lenses while using [GBNKEYWORD]?
It is not recommended for you to wear contact lenses prior to administration ZOXAN EYE/EAR DROPS for eye conditions as they might change colour due to ingredients present in the medicine. Contact your doctor before using ZOXAN EYE/EAR DROPS.
What are the side effects of ZOXAN EYE/EAR DROPS?
The most common side effects that occur due to ZOXAN EYE/EAR DROPS are white deposits on the cornea, ocular discomfort that includes stinging in the eyes, burning sensation, gritty feeling in the eye, irritation and redness of the eyes, as well as altered taste.
If I start feeling well, can I skip using ZOXAN EYE/EAR DROPS?
ZOXAN EYE/EAR DROPS is an antibiotic, if you fail to complete a course of antibiotics, some of the bacteria causing the infection may survive and could result in resistance to that strain of bacteria. This could lead to the worsening of the symptoms. Hence, you should complete the full course of ZOXAN EYE/EAR DROPS as prescribed by your doctor.
What will happen if I accidentally take overdosage of ZOXAN EYE/EAR DROPS?
If you or anyone else accidentally used too many drops of ZOXAN EYE/EAR DROPS into your eyes, immediately rinse your eyes with warm water. Consult a doctor immediately or visit the nearby hospital.
How does ZOXAN EYE/EAR DROPS work?
ZOXAN EYE/EAR DROPS is an antibacterial agent that acts by inhibiting bacterial replication by targeting the essential enzyme (DNA gyrase) inside the bacteria. As a result, it treats and prevents bacterial infections involving the eye and the ear.
What is ZOXAN EYE/EAR DROPS used for?
It is used to treat eye conditions such as corneal ulcers and superficial infections of the eye caused by bacteria, in particular Pseudomonas aeruginosa and other gram-negative bacteria which are resistant to usual treatment. ZOXAN EYE/EAR DROPS is also used for the topical treatment of inflammatory ear infections such as chronic suppurative otitis media, external otitis, malignant otitis externa and perioperatively in chronic otitis media. This medicine is indicated for use in adults and children above 1 year. Consult your doctor before using ZOXAN EYE/EAR DROPS.
REFERENCES
1. KD Tripathi. Fluoroquinolones antibiotics. Essentials of Medical Pharmacology. 7th Edition, 2013. Page - 709.
2. Redgrave, Liam S., Sam B. Sutton, Mark A. Webber, and Laura JV Piddock. Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success. Trends in microbiology. 2014. [Accessed on 10th June 2022] https://www.cell.com/trends/microbiology/pdf/S0966-842X(14)00089-4.pdf
3. Aldred KJ, Kerns RJ, Osheroff N. Mechanism of quinolone action and resistance. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. 2014. [Accessed on 10th June 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985860/
4. Ciplamed. [Revised in September 2019] [Accessed on 7th July 2022] https://www.ciplamed.com/content/ciplox-eyeear-drops
5. Novartis Pharma AG. [Revised in February 2013] [Accessed on 7th July 2022] https://www.novartis.com/sg-en/sites/novartis_sg/files/CILOXAN%20STERILE%20OPHTHALMIC%20AND%20OTIC%20SOLUTION%200.3%25.pdf
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