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Introduction About ZOSTUM O DRY SYRUP
ZOSTUM O DRY SYRUP contains Cefditoren which belongs to the group of medicines called Antibiotics. It is used to manage mild to moderate infections such as exacerbation of chronic bronchitis (increase in cough), pneumonia (infection of lung tissue), pharyngitis (sore throat)/tonsillitis (inflammation of tonsils), acute sinusitis (sinus infection), skin and soft tissue infection (Ex. muscle infection) in children of (2 months to 12 years of age).
ZOSTUM O DRY SYRUP is not recommended for use if you have carnitine deficiency or inborn errors of metabolism. ZOSTUM O DRY SYRUP should be used with caution in patients with severe kidney disease, colitis. Contact your doctor before taking it.
Inform your doctor before taking ZOSTUM O DRY SYRUP if you are pregnant or breastfeeding women. ZOSTUM O DRY SYRUP should be used with caution in children from 2 months to 12 years of age. Contact your doctor before taking it.
The most common side effects of taking ZOSTUM O DRY SYRUP are diarrhea, rash, urticaria. Contact your doctor if any of the symptoms worsen.
Uses Of ZOSTUM O DRY SYRUP
To manage mild to moderate infections such as:
- exacerbation of chronic bronchitis
- pneumonia
- pharyngitis /tonsillitis
- acute sinusitis
- skin and soft tissue infection
How ZOSTUM O DRY SYRUP Works
ZOSTUM O DRY SYRUP exerts its antibacterial action by inhibiting bacterial cell wall synthesis. Thus, it kills bacteria and manages infections effectively.
How to use ZOSTUM O DRY SYRUP
Take ZOSTUM O DRY SYRUP as advised by your physician. Shake well before use. Add freshly boiled and cooled water up to the ring mark on the bottle & shake well. Add more water if necessary to adjust the volume up to the ring mark.
The reconstituted suspension should be consumed within 7 days of preparation. Your physician will fix the correct dose and frequency for you based on your age, body weight and disease condition.
Side Effects Of ZOSTUM O DRY SYRUP
Common
- diarrhea
- rash, urticaria
Rare
Stop taking ZOSTUM O DRY SYRUP and contact your doctor immediately if you experience any of the following side effects:
- severe allergic reactions (such as sudden wheezing, difficulty in breathing, swelling of the eyelids, face, lips, throat, tongue or limbs, rash or itching (especially affecting your whole body)
- serious peeling or blistering of the skin
- severe diarrhoea, possibly with blood or mucus
- low blood sugar (glucose) level symptoms such as sweating, fast heartbeat, seizures and disturbances of consciousness
How To Manage Side Effects
Diarrhoea:
Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own for managing diarrhoea. Contact your doctor if your diarrhoea did not improve.
Skin rash:
Avoid hot baths because hot water can irritate your skin further. Do not scratch the affected area. Use sunscreen and wear protective clothing while going outside. Use unscented moisturizers to soothe and hydrate the affected area. Contact your doctor if your rashes worsen.
Warning & Precautions
Pregnancy
Inform your doctor before taking ZOSTUM O DRY SYRUP if you are pregnant or planning to be pregnant. Contact your doctor before taking it.
Breastfeeding
Inform your doctor before taking ZOSTUM O DRY SYRUP if you are breastfeeding woman. Contact your doctor before taking it.
Driving and Using Machines
ZOSTUM O DRY SYRUP does not affect your ability to drive or operate machines.
Kidney
ZOSTUM O DRY SYRUP should be used with caution in patients with severe kidney disease. Contact your doctor before taking it.
Allergy
Do not take ZOSTUM O DRY SYRUP if you are allergic to cefditoren, other cephalosporins or to other ingredients of this medicine.
Others
ZOSTUM O DRY SYRUP is not recommended for use if you:
- have carnitine deficiency or inborn errors of metabolism
Before taking ZOSTUM O DRY SYRUP, inform your doctor if you:
- have a history of allergic reactions to penicillins or other drugs
- have a history of gastrointestinal disease, especially inflammation of the colon (colitis)
- are undergoing any blood or urine tests
Use in paediatrics:
ZOSTUM O DRY SYRUP should be used with caution in children from 2 months to 12 years of age. Contact your doctor before taking it.
Interactions
A. Drug-Drug interactions:
Before taking ZOSTUM O DRY SYRUP, inform your doctor if you are taking any of the following medicine:
- medicines used to relieve indigestion and heartburn (aluminium and magnesium hydroxide, famotidine)
- probenecid (medicine used to manage gout)
Overdosage:
If you or anyone else accidentally take too much of ZOSTUM O DRY SYRUP, consult your doctor immediately or visit the nearby hospital.
Synopsis
| Drug | : | Cefditoren |
| Pharmacological Category | : | Cephalosporin Antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Dry Syrup |
More Information
- Keep ZOSTUM O DRY SYRUP out of the sight and reach of children
- Store ZOSTUM O DRY SYRUP in a cool place
FAQs About ZOSTUM O DRY SYRUP
Q: Who should not use ZOSTUM O DRY SYRUP?
A: ZOSTUM O DRY SYRUP is not recommended in patients with carnitine deficiency or inborn errors of metabolism and allergic history to cefditoren, other cephalosporins. Contact your doctor before taking ZOSTUM O DRY SYRUP.
Q: How often can I use ZOSTUM O DRY SYRUP?
A: Take ZOSTUM O DRY SYRUP as advised by your physician. Generally, it will be prescribed thrice daily after meals. Your physician will fix the correct dose and frequency for you based on your age, body weight and disease condition.
Q: Does ZOSTUM O DRY SYRUP cause diarrhoea?
A: Yes. ZOSTUM O DRY SYRUP may cause diarrhoea. Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Do not take any medicine on your own to manage diarrhoea. Contact your doctor if your diarrhoea does not improve.
Q: What If I forget to take ZOSTUM O DRY SYRUP?
A: If you forget to take a dose of ZOSTUM O DRY SYRUP, take it as soon as you remember and then continue your management as usual. Do not take medicine twice to make up for the forgotten dose.
Q: How do you take ZOSTUM O DRY SYRUP?
A: Take ZOSTUM O DRY SYRUP as advised by your physician. Shake well before use. Add freshly boiled and cooled water up to the ring mark on the bottle & shake well. Add more water if necessary to adjust the volume up to the ring mark. The reconstituted suspension should be consumed within 7 days of preparation. Your physician will fix the correct dose and frequency for you based on your age, body weight and disease condition.
References
1. Bertram G. Katzung. Beta-Lactam & Other Cell Wall- & Membrane-Active Antibiotics. Basic & Clinical Pharmacology. Fourteenth Edition. 2018. Page – 804, 805.
2. Wellington K, Curran MP. Cefditoren pivoxil: a review of its use in the treatment of bacterial infections. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. 2004. [Accessed on 24th December 2022] https://pubmed.ncbi.nlm.nih.gov/15516158/
3. Poachanukoon O, Tangsathapornpong A, Tanuchit S. A Comparison of Cefditoren Pivoxil 8-12 mg/kg/day and Cefditoren Pivoxil 16-20 mg/kg/day in Treatment of Children With Acute Presumed Bacterial Rhinosinusitis: A Prospective, Randomized, Investigator-Blinded, Parallel-Group Study. NIH National Library of Medicine, National Center for Biotechnology Information. PubMed Central. June 2015. [Accessed on 24th December 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451537/
4. Zostum-O (Cefditoren). Zuventus Healthcare Limited. [Accessed on 24th December 2022] http://www.zuventus.co.in/patient_wise_products_selected.aspx?Medi_Id=337
Useful Diagnostic Tests
- Complete Blood Count
- Peripheral Smear Examination
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