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Zofix 100mg Dry Syrup 30ml
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INTRODUCTION
ZOFIX 100MG DRY SYRUP contains Cefixime which belongs to the group of medicines called Antibiotics. It is used to treat bacterial infections of the ear, nose, throat, sinus, respiratory tract (bronchus, lungs), urinary tract, genital tract and biliary tract in children (aged between 6 months up to 12 years). It can also be used in the treatment of typhoid fever.
A bacterial infection can be defined as a proliferation of various harmful strains of bacteria in the body. They can affect any part(s) of the body including the respiratory tract, urinary tract, reproductive tract, eyes, ears, skin, soft tissue, or bones.
Therapy with ZOFIX 100MG DRY SYRUP should be continued for the stipulated duration instructed by your doctor even if your child feels better during the midway of the therapy. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control.
Prior to the therapy, inform your doctor about the child’s pre-existing disease conditions such as any stomach problems or kidney problems as a precaution. The most common side effects of taking ZOFIX 100MG DRY SYRUP are nausea, vomiting, diarrhea, stomach pain and bloating. Consult your doctor immediately if any of these side effects worsen in your child.
USES OF ZOFIX 100MG DRY SYRUP
It is used in children (aged between 6 months up to 12 years) to treat various bacterial infections such as:
- Ear infections (such as otitis media)
- Sinus infections (such as sinusitis)
- Throat infections (such as tonsillitis and pharyngitis)
- Respiratory tract infections (such as bronchitis and pneumonia)
- Urinary tract infections (such as cystitis and kidney infections)
- Genital tract infection (such as gonococcal urethritis)
- Stomach and biliary tract infections (such as cholecystitis)
- Typhoid fever
HOW ZOFIX 100MG DRY SYRUP WORKS
ZOFIX 100MG DRY SYRUP is a powerful antibiotic with bacteriostatic properties. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis. Unlike other cephalosporins, it can also remain unaffected by the toxic proteins produced by the bacteria (such as beta lactamases). Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication and reduce the severity of the infection.
DIRECTIONS FOR USE
Administer ZOFIX 100MG DRY SYRUP to your child as advised by your physician. It can be taken with or without food.
Shake the bottle well to loosen the dry powder. Add the sterile water provided with this pack up to the ring mark present on the bottle surface. Add extra water if required to adjust the volume up to the ring mark. Close the bottle tightly and shake the mixture well.
The quantity (ml) which is required to be administered to your child will be decided by your doctor. Do not stop therapy with ZOFIX 100MG DRY SYRUP once the symptoms subside in your child. It is important to consume ZOFIX 100MG DRY SYRUP for the stipulated duration recommended by your doctor to achieve control over the infection.
SIDE EFFECTS OF ZOFIX 100MG DRY SYRUP
COMMON
- nausea or vomiting
- stomach pain, indigestion, diarrhoea or wind
- headache, dizziness
- itchiness of the genital (or vaginal) areas
RARE
Stop therapy with ZOFIX 100MG DRY SYRUP and contact your doctor immediately if your child experiences any of the following side effects such as:
- signs of severe allergic reactions (such as skin rash, itching, swelling of the face, lips, throat or tongue causing difficulty in breathing or swallowing)
- severe skin reactions (such as widespread skin rash, blistering, peeling or bleeding on any part of the skin with fever, chills, enlarged lymph nodes and malaise or pink or reddish skin lesions on palms or soles)
- unusual bleeding or bruising, bleeding from the nose or gums with pale skin, tiredness, chills and shortness of breath
- bloody urine or difficulties in urination
- signs of brain damage (such as fits with or without confusion, lack of alertness and unusual muscle movements)
- signs of stomach damage causing severe uncontrollable watery diarrhoea, feeling weak and fever
HOW TO MANAGE SIDE EFFECTS
Nausea or vomiting:
Make sure that your child takes ZOFIX 100MG DRY SYRUP with, or just after meals. Provide your child with simple meals. Avoid them giving oil rich or spicy foods. Please consult your doctor immediately if your child experience severe nausea or vomiting.
Diarrhoea:
Make sure that your child drinks plenty of fluids, such as water or fruit juice to keep themself hydrated. Consuming ORS can also be beneficial. If diarrhea worsens, contact your doctor immediately.
WARNING & PRECAUTIONS
DRIVING AND USING MACHINES
Do not let your child drive or handle any heavy tools if their ability is affected by ZOFIX 100MG DRY SYRUP.
KIDNEY
ZOFIX 100MG DRY SYRUP should be used with caution in children with kidney problems. Therefore, consult your doctor before taking it.
ALLERGY
Do not administer ZOFIX 100MG DRY SYRUP to your child if your child is allergic to Cefixime or to any other cephalosporin antibiotics including penicillins.
OTHERS
Before taking ZOFIX 100MG DRY SYRUP, inform your doctor if your child:
- ever had colitis (inflammation of the colon)
- is going to have any blood or urine test in the upcoming days
Use in paediatrics:
ZOFIX 100MG DRY SYRUP can be used in children (aged between 6 months to 12 years). It is not recommended for use in children aged below 6 months. However, consult your doctor for advice.
INTERACTIONS
A. Drug-Drug interactions:
Before taking ZOFIX 100MG DRY SYRUP, inform your doctor if your child is taking any of the following medicines such as:
- warfarin (medicine used for blood thinning)
- carbamazepine (a medicine used for epilepsy)
Overdosage:
If your child accidentally swallowed more ZOFIX 100MG DRY SYRUP, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Cefixime |
| Pharmacological Category | : | Cephalosporin Antibiotics |
| Therapeutic Indication | : | Bacterial infections |
| Dosage Forms | : | Tablet, Capsule, Dispersible tablet, Drops, Dry Syrup, Oral Suspension |
MORE INFORMATION
- Keep ZOFIX 100MG DRY SYRUP out of reach of children
- Before reconstitution: store ZOFIX 100MG DRY SYRUP at room temperature
- After reconstitution: store ZOFIX 100MG DRY SYRUP in a refrigerator
- Use the reconstituted suspension within 7 days from the date of opening
FAQs ABOUT ZOFIX 100MG DRY SYRUP
What is the use of ZOFIX 100MG DRY SYRUP?
ZOFIX 100MG DRY SYRUP is used to treat bacterial infections of the ear, nose, throat, sinus, respiratory tract (bronchus, lungs), urinary tract, biliary tract and genital tract. It can also be used in the treatment of typhoid fever.
How ZOFIX 100MG DRY SYRUP works in my body?
ZOFIX 100MG DRY SYRUP is a powerful antibiotic with bacteriostatic properties. It kills the susceptible bacteria by blocking the bacterial cell wall synthesis. Unlike other cephalosporins, it can also remain unaffected by the toxic proteins produced by the bacteria (such as beta lactamases). Collectively, these actions destroy the susceptible bacteria, prevent their further growth and multiplication and reduce the severity of the infection.
Can ZOFIX 100MG DRY SYRUP be used in patients with kidney problems?
ZOFIX 100MG DRY SYRUP should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
How should I take ZOFIX 100MG DRY SYRUP?
Shake the bottle well to loosen the dry powder. Add the sterile water provided with this pack up to the ring mark present on the bottle surface. Add extra water if required to adjust the volume up to the ring mark. Close the bottle tightly and shake the mixture well. The quantity (ml) which is required to be administered to your child will be decided by your doctor.
For how long should I take ZOFIX 100MG DRY SYRUP?
ZOFIX 100MG DRY SYRUP should be taken for the stipulated duration prescribed by your doctor. Do not skip the medicine or stop taking it on your own as it may cause the infection to reappear.
What are the common side effects of taking ZOFIX 100MG DRY SYRUP?
The most common side effects of taking ZOFIX 100MG DRY SYRUP are nausea, vomiting, diarrhea, stomach pain and bloating. Consult your doctor immediately if any of these side effects worsen in your child.
Can I stop taking ZOFIX 100MG DRY SYRUP once my symptoms subside?
Do not stop taking ZOFIX 100MG DRY SYRUP once your symptoms subside. It is important to take the full course of ZOFIX 100MG DRY SYRUP to achieve better results. Failing to complete the full course of the therapy or skipping doses in between the therapy may not result in adequate infection control. It may also cause your symptoms to reappear.
Can the use of ZOFIX 100MG DRY SYRUP cause diarrhea?
ZOFIX 100MG DRY SYRUP may cause diarrhea in some children. If your child experiences diarrhea, drink plenty of fluids, such as water or fruit juice to keep yourself hydrated. Consuming ORS can also be beneficial. If diarrhea worsens contact your doctor immediately.
What should I do if I forgot to take a dose of ZOFIX 100MG DRY SYRUP?
If you forgot to take a dose of ZOFIX 100MG DRY SYRUP, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose to compensate the forgotten dose.
REFERENCES
1. K.D. Tripathi. Beta-Lactam Antibiotics. Essentials of Medical Pharmacology. 7th Edition, 2013. Page - 728.
2. Ben JK Tan. Cefixime use in children: When and why. NIH. National Library of Medicine, National Center of biotechnology Information. PubMed Central. July-August 1995. [Accessed on 29th September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327925/
3. Ziprax Dispersible Tablet/Dry Syrup (Cefixime). Cipla Ltd. [Revised in January 2020]. [Accessed on 29th September 2022] https://www.ciplamed.com/content/ziprax-dispersible-tablets-dry-syrup
4. Taxim O Drops. Cefixime For Oral Suspension. Alkem Labs. [Revised in November 2019] [Accessed on 29th September 2022] https://www.alkemlabs.com/pdf/adverse/Taxim-O%20Paedatric%20Drops.pdf
5. Lupin Pharmaceuticals Inc. U.S. Food and Drug Administration. [Revised in May 2012] [Accessed on 29th September 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203195s000lbl.pdf
6. Soigner pharma. Fycep Drops. Cefixime for Oral Suspension. [Accessed on 29th September 2022] https://www.soignerpharma.com/product/cefixime-fycef-drops/
7. Hetero healthcare. Hifen 50mg Dry Syrup. Cefixime 50 mg. [Accessed on 29th September 2022] https://www.heterohealthcare.com/hifen-50mg-dry-syru
8. Cefixime Tablet 200mg and Cefixime Oral Suspension. Central Drugs Standard Control Organization. February 1993. [Accessed on 29th September 2022] https://cdscoonline.gov.in/CDSCO/Drugs
USEFUL DIAGNOSTIC TESTS
- Complete Blood Count
- Peripheral Smear Examination
- Kidney Function Test
AUTHOR DETAILS
Written By Srilekha. R, B.Pharm
Last updated on 03 Oct 2022 | 12:38 PM(IST)
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