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Zofer MD 4mg Tablet 10'S
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INTRODUCTION
ZOFER MD 4MG TABLET contains Ondansetron, which belongs to a group of medicines called Anti-emetics. It is used to treat and prevent nausea and vomiting induced by chemotherapy or radiotherapy. ZOFER MD 4MG TABLET is also used after surgeries (operation) to prevent nausea and vomiting.
Before taking ZOFER MD 4MG TABLET, inform your doctor if you have severe constipation, heart or liver problems, imbalance with the levels of salts in the blood, such as potassium, sodium and magnesium or if you have been scheduled for any surgery.
ZOFER MD 4MG TABLET is not recommended for use during pregnancy. This medicine may pass through the breast milk hence it is not recommended during breastfeeding. Consult your doctor before taking this medicine.
The dose of ZOFER MD 4MG TABLET will depends on the age, body weight and disease condition of your child. Dosage adjustment is not required in elderly patients, hence consult your doctor before taking ZOFER MD 4MG TABLET.
The most common side effects of taking ZOFER MD 4MG TABLET includes headache, flushing and constipation. Consult your doctor if any of these above symptoms gets worse.
USES OF ZOFER MD 4MG TABLET
- Used to treat and prevent nausea and vomiting induced by chemotherapy, radiotherapy and surgery
HOW ZOFER MD 4MG TABLET WORKS
ZOFER MD 4MG TABLET is a serotonin 5-HT3 receptor antagonist (specific chemical receptor) which works by blocking serotonin receptors in CTZ chemoreceptor trigger zone (zone in the brain that is responsible for causing nausea and vomiting).
DIRECTIONS FOR USE
Take ZOFER MD 4MG TABLET as advised by your physician. It can be taken with or without food.
For Tablet, Capsule: Swallow ZOFER MD 4MG TABLET with a glass of water. Do not crush or chew the medicine.
For Dispersible Tablet: Disperse the medicine in the specified quantity of water as mentioned in the label. Consume the medicine immediately after reconstitution.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and severity of the infection.
SIDE EFFECTS OF ZOFER MD 4MG TABLET
COMMON
- headache
- flushing (feeling of warmth)
- constipation
UNCOMMON
- uncontrolled body movements along with upward rolling movement of the eyeballs
- fits (seizures)
- irregular heartbeat (fast or slow)
- chest pain
- fainting or feeling dizzy (low blood pressure)
- hiccups
RARE
- visual disturbances like blurred vision
- effects of heart rhythms resulting in feeling lightheaded or loss of consciousness
Stop taking ZOFER MD 4MG TABLET and contact your doctor if you experience any of the following side effects:
- sudden wheezing and chest pain or tightness
- swelling of eyelids, face, lips, mouth or tongue
- skin rash, red spots or lumps under your skin (hives) or anywhere on the body
HOW TO MANAGE SIDE EFFECTS
Headache:
Take rest. Have good amount of sleep. Have a balanced diet and at regular intervals. Add more fluids to your diet. Drink plenty of water to replenish water stores.
Constipation:
Eat plenty of fibre rich foods such as fresh fruits, vegetables, and cereals. Drink water and exercise regularly. Contact your doctor if constipation persists.
Dizziness:
Lie down until the dizziness passes and get up slowly. Do not bend down suddenly. Get a lot of rest. Walk slowly and carefully. Take plenty of fluids. Avoid drinking coffee, alcohol or smoking. Consult your doctor if the condition persists for long or gets worsened.
WARNING & PRECAUTIONS
PREGNANCY
ZOFER MD 4MG TABLET is generally not recommended for use during pregnancy unless considered clearly necessary. Consult your doctor before taking ZOFER MD 4MG TABLET.
BREASTFEEDING
ZOFER MD 4MG TABLET is not recommended for use in breastfeeding women as it may pass through the breast milk. Consult your doctor before taking ZOFER MD 4MG TABLET.
DRIVING AND USING MACHINES
Do not drive or operate any machines if you feel dizzy or uneasy after taking ZOFER MD 4MG TABLET.
LIVER
ZOFER MD 4MG TABLET should be used with caution in patients with liver problems. Consult your doctor before taking ZOFER MD 4MG TABLET.
ALLERGY
Do not take ZOFER MD 4MG TABLET if you are allergic to ondansetron, granisetron or palonosetron or to any other ingredients of this medicine.
HEART DISEASE
ZOFER MD 4MG TABLET should be used with caution in patients with heart diseases such as uneven heartbeats (arrhythmias) or congestive heart failure. Consult your doctor before taking ZOFER MD 4MG TABLET.
OTHERS
Before taking ZOFER MD 4MG TABLET, inform your doctor if you:
- have a blockage in your gut
- have problems with the levels of salts in the blood (such as potassium, sodium and magnesium)
- are intolerant to some sugars (Ex. lactose intolerance)
Use in pediatrics:
Your doctor will give the right dose of ZOFER MD 4MG TABLET depends on your child’s age, body weight and disease condition. Consult your doctor before taking ZOFER MD 4MG TABLET.
Use in geriatrics:
Dosage adjustment is not required in elderly patients, hence consult your doctor before taking ZOFER MD 4MG TABLET.
INTERACTIONS
A. Drug-Drug Interactions:
Before taking ZOFER MD 4MG TABLET, inform your doctor, if you are taking any of the following medicine:
- apomorphine (used to treat Parkinson’s disease)
- medicines used to treat epilepsy (Ex. phenytoin, carbamazepine)
- medicines used to treat lung infections like Tuberculosis (Ex. rifampicin)
- tramadol, methadone (medicine used to provide relief from pain)
- medicines used for psychotic disorders (Ex. haloperidol)
- medicines used to treat heart problems such as abnormal heart beats (Ex. amiodarone) and/or high blood pressure (Ex. atenolol, timolol)
- cancer medicines (Ex. doxorubicin, daunorubicin, monoclonal, trastuzumab)
- erythromycin, ketoconazole (used to treat infections)
- medicines used to treat depression and anxiety (ex. fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram, venlafaxine, duloxetine escitalopram)
Overdosage:
If you or anyone else accidentally takes too much of ZOFER MD 4MG TABLET, consult your doctor immediately or visit the nearby hospital.
SYNOPSIS
| Drug | : | Ondansetron |
| Pharmacological Category | : | Serotonin antagonist |
| Therapeutic Indication | : | Nausea and Vomiting in patients (undergoing chemotherapy, radiotherapy, surgery) |
| Dosage Forms | : | Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille |
MORE INFORMATION
- Keep the medicine out of reach in children
- Store ZOFER MD 4MG TABLET at room temperature
FAQs ABOUT ZOFER MD 4MG TABLET
Q: Is ZOFER MD 4MG TABLET a chemo drug?
A: No, it is not a chemo drug. It belongs to a group of medicines called serotonin antagonists and used to treat side effects caused due to chemotherapy.
Q: Is ZOFER MD 4MG TABLET safe in pregnancy?
A: ZOFER MD 4MG TABLET is not recommended for use in pregnancy unless clearly necessary as it is not known whether it may cause harm to the unborn baby. Contact your doctor before taking.
Q: What ZOFER MD 4MG TABLET is used for?
A: ZOFER MD 4MG TABLET is used to treat nausea and vomiting caused by medical treatments like chemotherapy, radiotherapy or surgery.
Q: For how long should you take ZOFER MD 4MG TABLET?
A: Your doctor will advise you on how long you should continue to take ZOFER MD 4MG TABLET. Consult your doctor from time to time to review your treatment and assess your symptoms.
Q: What happens if you take more ZOFER MD 4MG TABLET than your required dose?
A: If you or anyone else accidentally takes too much of ZOFER MD 4MG TABLET, consult your doctor immediately or visit the nearby hospital.
Q: What side effects are seen with ZOFER MD 4MG TABLET?
A: The most common side effects of taking ZOFER MD 4MG TABLET are headaches, flushing (feeling of warmth), constipation. Consult your doctor if above side effects got worse.
REFERENCES
1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.
2. LTS Lohmann Therapie-Systeme AG Lohmannstrasse. Andernach GERMANY [Revised April 2022] [Accessed on 29 September 2022] https://www.medicines.org.uk/emc/files/pil.9595.pdf
3. Koland M, Sandeep V, Charyulu N. Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. J Young Pharm. 2010 Jul;2(3):216-22. [Accessed on 29 September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964757/
4. Kumria R, Gupta V, Bansal S, Wadhwa J, Nair AB. Oral buccoadhesive films of ondansetron: Development and evaluation. Int J Pharm Investig. 2013 Apr;3(2):112-8. [Accessed on 29 September 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757901/
5. Ondansetron Soluble Films. [Accessed on 29 September 2022] https://my.clevelandclinic.org/health/drugs/20819-ondansetron-soluble-films
6. Myoclinic. [Accessed on 29 September 2022] https://www.mayoclinic.org/drugs-supplements/ondansetron-oral-route-oromucosal-route/proper-use/drg-20074421
USEFUL DIAGNOSTIC TESTS
- Complete blood count
AUTHOR DETAILS
Written By Dr. Janet.C, Pharm.D
Last updated on 20 Jan 2023 | 06:15 PM(IST)
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