Zimivir 1000mg Tablet 3'S

Viral infections Rx required

Best Price*  ₹ 175.28
MRP ₹219.10
(Inclusive of all taxes) *3 Tablet(s) in a Strip * Mkt: Glaxosmithkline Pharmaceuticals Ltd * Country of Origin: India * Delivery charges if applicable will be applied at checkout

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INTRODUCTION

ZIMIVIR contains valaciclovir which belongs to the group of medicines called antiviral agents. It is used in the treatment of cold sores (small, fluid-filled, painful blisters around the oral cavity) in adults and in children over 12 years of age. It can also be used to treat initial and recurrent episodes of HSV infections of the eye, skin and genital herpes in adult patients and also prevents its recurrence or transmission. Genital herpes is a sexually transmitted viral infection caused by herpes simplex virus which is characterized by genital pain, sores, ulcers and scabs.

ZIMIVIR can also be used in the treatment of Herpes zoster infection (shingles) in adults and chickenpox in children (aged between 2-18 years). Chicken pox usually causes an itchy, blister-like rash on the face, chest and back, whereas shingles appears as a single stripe of blisters on the left or right side of your body. It can also prevent infection with cytomegalovirus (CMV) after organ transplants in adults and children above 12 years.

Valacyclovir works by killing or stopping the growth and multiplication of virus in human cells. During the treatment, your doctor will regularly monitor the functions of your brain and kidney especially in aged patients (>65 years) to avoid unwanted side effects. It is important to drink plenty of water regularly during the day to reduce the risk of side effects of the brain and kidneys.

This medicine can be taken with or without food. Patients taking ZIMIVIR either for the treatment or for the prevention of recurrence of genital herpes should always practice safe sex methods (including the use of condoms). Patients having genital sores or blisters should not have sex, as a precaution to avoid sexual transmission of the infection. The most common side effects of taking this medicine are nausea, vomiting, diarrhea, dizziness and headache. Contact your doctor if any of the symptoms bothers you. Before taking this medicine, inform your doctor if you have any liver or kidney problems. It is not recommended for use in pregnant or lactating women and in children (aged less than 12 years). Consult your doctor before taking.  

USES OF ZIMIVIR

  • Treats cold sores in adults and in children (aged above 12 years)
  • Treats and prevents HSV infections of the eye, skin and genital herpes in adult patients
  • Treats shingles in adult patients
  • Treats chickenpox in children (aged above 2 years)
  • Prevents cytomegalovirus (CMV) infection after any organ transplants in adults and children above 12 years

HOW ZIMIVIR WORKS

Valacyclovir works by killing or stopping the growth and multiplication of virus in human cells. It gets incorporated into the viral DNA and competitively inhibits the viral DNA polymerase enzyme which stops lengthening of viral DNA strand, prevents further multiplication of new viral cells and clears up your infection.

DIRECTIONS FOR USE

Take ZIMIVIR as directed by your physician. It can be taken with or without meals. Swallow the medicine as whole with a plenty of water. Do not crush or chew the medicine. Drink plenty of water regularly during the day while taking this medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and health condition. Continue to take this medicine, as long as your doctor tells you to do so, to obtain better results.

SIDE EFFECTS OF ZIMIVIR

SERIOUS

  • severe allergic reactions (such as skin rash, itching, swelling of the lips, face, neck and throat, difficulty in breathing and a fall in blood pressure leading to collapse)
  • Drug reaction with eosinophilia and systemic symptoms (DRESS; symptoms includes extended skin rash with fever, increased levels of liver enzymes, eosinophilia and enlarged lymph nodes)

COMMON

  • headache
  • nausea or vomiting
  • dizziness
  • diarrhea
  • photosensitivity (skin reaction after exposure to sunlight)
  • skin rash or itching

RARE

  • ataxia (lack of coordination)
  • dysarthria (slow or slurred speech)
  • fits (seizures)
  • encephalopathy (altered brain function)
  • coma (loss of consciousness)
  • delirium (confused or disturbed thoughts)

HOW TO MANAGE SIDE EFFECTS

Nausea or vomiting:

Try taking this medicine with, or just after meals. Stick to simple meals. Do not eat rich or spicy food.

Diarrhea:

Drink lots of fluids, such as water or juice, to avoid dehydration. Do not take any medicines without speaking to a doctor.

Skin rash or itching:

Avoid hot showers because hot water can irritate the skin. Do not rub or scratch the affected area. Use sunscreen and protective clothing when outdoors. Regularly use moisturizers to soothe and hydrate the affected area. If it does not get better, contact your doctor.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid traveling, driving or operating any tools or machines while you are feeling dizzy. If the symptom still persists, contact your doctor for advice.

WARNING & PRECAUTIONS

PREGNANCY

ZIMIVIR should be used with caution in pregnant women. Consult your doctor before taking this medicine.

BREASTFEEDING

ZIMIVIR should be used with caution in breastfeeding mothers. Consult your doctor before taking this medicine.

DRIVING AND USING MACHINES

Do not drive or operate any machines if your ability is affected by this medicine.

KIDNEY

ZIMIVIR should be taken with caution in patients with kidney problems. Consult your doctor for advice.

LIVER

ZIMIVIR should be taken with caution in patients with liver problems. Consult your doctor for advice.

ALLERGY

Do not take this medicine if you are allergic to valaciclovir or acyclovir.

INTERACTIONS

Talk to your doctor, if you are taking,

  • aminoglycosides (used to treat bacterial infections) e.g. streptomycin, neomycin, kanamycin
  • methotrexate (used to treat psoriasis, arthritis and other autoimmune disease)
  • pentamidine (used to treat pneumonia)
  • foscarnet (used to treat an eye infection called cytomegalovirus retinitis)
  • ciclosporin or tacrolimus (used to prevent graft rejection)
  • probenecid (a medicine used to treat gout)
  • cimetidine (used to treat stomach ulcers)

SYNOPSIS

Drug :   Valaciclovir
Pharmacological Category :   Antiviral agent
Therapeutic Indication :  

Cold sores, HSV infection of eye & skin, Genital herpes, Chicken pox, Shingles, Prevention of CMV infection

Dosage Forms :   Tablet

MORE INFORMATION

Store below 20-25°C and keep out of reach of children.

FAQs ABOUT ZIMIVIR

My age is 70 and I have kidney problems. Can I take ZIMIVIR?

Since you are an elderly patient with kidney problems, your doctor will prescribe a suitable dose for you. However, constant monitoring of kidney function is required for you. Drink plenty of water while taking this medicine as it may reduce the risk of adverse effects. Your doctor will also closely monitor you for signs such as feeling confused, agitated or unusually sleepy. If you develop any of these effects contact your doctor immediately.

Can I take ZIMIVIR for chickenpox?

Yes. It can be used to treat chickenpox only in children (aged between 2-18 years). However, contact your doctor before taking.

What will happen if I accidentally take too much ZIMIVIR?

If you accidentally took too much of this medicine, contact your doctor immediately for help. Symptoms of overdosage might include nausea, vomiting, confusion, agitation, hallucination (seeing or feeling things that are not there), feel less aware or loss of consciousness.

REFERENCES

1. KD. Tripathi. Antiviral Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page - 800.

2. Edward P. Acosta and Charles Flexner. Antiviral agents (non-retroviral). Goodman & Gilman’s: The Pharmacological basics of Therapeutics. 12th Edition. New York McGraw Hill Medical 2011. Page - 1594-1600.

3. GlaxoSmithKline. VALTREX(Valacyclovir) Once Daily for Viral Shedding In Subjects Newly Diagnosed With HSV-2. NIH U.S. National Library of Medicine ClinicalTrials.gov. [Revised on March 2018] [Accessed 26th December 2020] https://clinicaltrials.gov/ct2/show/NCT00306293

4. Spotswood L. Spruance, Terry M. Jones, Mark M. Blatter, Mauricio Vargas-Cortes, Judy Barber, Joanne Hill, Donna Goldstein, Margaret Schultz and Valacyclovir Cold Sore Study Group. High-Dose, Short-Duration, Early Valacyclovir Therapy for Episodic Treatment of Cold Sores: Results of Two Randomized, Placebo-Controlled, Multicenter Studies. NCBI; PMC US National Library of Medicine, National Institute of Health. March 2003. [Accessed 26th December 2020] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149313/

5. Cipla. Ltd. VALCIVIR Tablets (Valacyclovir hydrochloride). Ciplamed.com. [Revised on April 2018] [Accessed 26th December 2020] https://www.ciplamed.com/content/valcivir-tablets

6. APL Swift Services (Malta) Limited. Electronic Medicines Compendium (EMC); [Revised on July 2020] [Accessed 26th December 2020] https://www.medicines.org.uk/emc/files/pil.3037.pdf

7. Sun Pharmaceutical Industries Europe B.V. and Terapia S.A. Electronic Medicines Compendium (EMC); [Revised on May 2019] [Accessed 26th December 2020] https://www.medicines.org.uk/emc/files/pil.4349.pdf

USEFUL DIAGNOSTIC TESTS

  • Herpes Simplex Virus 1 DNA PCR
  • Herpes Simplex Virus 1 IgG
  • Herpes Simplex Virus 2 DNA PCR
  • Herpes Simplex Virus 2 IgG
  • Herpes Simplex Virus 2 IgM

PRODUCT DETAILS

    Net Qty
    1
    Item Weight
    10
    Ingredient
    VALACICLOVIR 1000MG
    Hsn Code
    30049099
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

Zimivir 1000mg Tablet 3'S

Zimivir 1000mg Tablet 3'S Mkt: Glaxosmithkline Pharmaceuticals Ltd

M.R.P.: Rs.219.10
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