INTRODUCTION
ZENGAT 0.5% EYE DROPS contains Gatifloxacin which belongs to the group of medicines called Antibiotics. It is used to treat bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).
ZENGAT 0.5% EYE DROPS should be used with caution in pregnant and breastfeeding women as insufficient data is available on this.
ZENGAT 0.5% EYE DROPS is not recommended for children below 1 year of age. Therefore, contact your doctor before using.
The most common side effects of using ZENGAT 0.5% EYE DROPS include worsening of conjunctivitis, eye irritation, dysgeusia and eye pain. Contact your doctor if any of the side effects worsen.
USES OF ZENGAT 0.5% EYE DROPS
- Used to treat bacterial conjunctivitis
HOW ZENGAT 0.5% EYE DROPS WORKS
ZENGAT 0.5% EYE DROPS works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).
DIRECTIONS FOR USE
Always use ZENGAT 0.5% EYE DROPS as advised by your physician. It is for ophthalmic use only. Check the label for directions for use. Your doctor will prescribe the right dose depends on your age, body weight and disease condition.
SIDE EFFECTS OF ZENGAT 0.5% EYE DROPS
COMMON
- eye irritation or pain
- dysgeusia (taste disorder)
UNCOMMON
- conjunctival haemorrhage (tiny blood vessel breaks just underneath the clear surface of your eye)
- dry eye
- eye discharge
- eyelid oedema
- headache
- increased lacrimation
- keratitis (inflammation of the cornea)
- red eye
- papillary conjunctivitis (eyelid gets red, swollen and irritated)
- reduced visual acuity
RARE
- steven-johnson syndrome
Stop using ZENGAT 0.5% EYE DROPS and contact your doctor immediately if you experience any of the following side effects:
- anaphylactic reactions (symptoms include eye allergy and allergic dermatitis, nausea, pruritis and blurred vision)
- angioedema
- blepharitis
- dyspnoea
WARNING & PRECAUTIONS
PREGNANCY
There is no proper information about the use of ZENGAT 0.5% EYE DROPS in pregnant women. Consult your doctor before using.
BREASTFEEDING
There is no proper information about the use of ZENGAT 0.5% EYE DROPS in breastfeeding women. Consult your doctor before using.
ALLERGY
Do not use ZENGAT 0.5% EYE DROPS if you are allergic to Gatifloxacin or any other components of this medicine.
OTHERS
Use in pediatrics:
Use of ZENGAT 0.5% EYE DROPS is not recommended in children below 1 year of age as the safety and effectiveness in this age group has not been established. Contact your doctor before using.
INTERACTIONS
A. Drug-Drug Interactions:
Tell your doctor if you are using or taking any other medicines including prescription, non-prescription and herbal supplements.
Overdosage:
If you accidentally uses too much ZENGAT 0.5% EYE DROPS, contact your doctor immediately.
SYNOPSIS
| Drug | : | Gatifloxacin |
| Pharmacological Category | : | Antibiotics |
| Therapeutic Indication | : | Bacterial Conjunctivitis |
| Dosage Forms | : | Drops, Eye drops, Eye/Ear drops, Ophthalmic solution, Solution, Ointment, tablet, Eye Ointment |
MORE INFORMATION
- Keep ZENGAT 0.5% EYE DROPS out of sight and reach of children
- Store ZENGAT 0.5% EYE DROPS below 25°C
FAQs ABOUT ZENGAT 0.5% EYE DROPS
Is ZENGAT 0.5% EYE DROPS safe for use during pregnancy?
ZENGAT 0.5% EYE DROPS should be used with caution in pregnant and breastfeeding women as insufficient data is available on this. Contact your doctor before using.
What are the side effects of ZENGAT 0.5% EYE DROPS?
The most common side effects of using ZENGAT 0.5% EYE DROPS include worsening of conjunctivitis, eye irritation, dysgeusia and eye pain. Contact your doctor if any of the symptoms worsen.
What is ZENGAT 0.5% EYE DROPS used for?
It is used to treat bacterial conjunctivitis caused by strains of aerobic gram-positive bacteria (Ex. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae) and aerobic gram-negative bacteria (Ex. Haemophilus influenzae).
What is the mechanism of action of ZENGAT 0.5% EYE DROPS?
Gatifloxacin works by inhibiting DNA gyrase (an enzyme that helps in replication, transcription and repair of bacterial DNA) and topoisomerase IV (an enzyme that helps in portioning of chromosomal DNA during bacterial cell division).
REFERENCES
1. K.D. Tripathi. Sulfonamides, Cotrimoxazole and Quinolones. Essentials of Medical Pharmacology. 7th Edition. 2013. Page 713.
2. Akorn Pharmaceuticals. U.S. Food and Drugs Administration. [Revised in Mar 2022] [Accessed on 7th Nov 2022] https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=14312de6-67d4-4de2-854c-ef764090dd83
3. Allergan. U.S. Food and Drugs Administration. [Revised in Sep 2016] [Accessed on 7th Nov 2022] https://www.rxabbvie.com/pdf/zymaxid_pi.pdf
PRODUCT DETAILS
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.